RU2743347C2 - Пролекарства карбидопа и l-dopa и их применение для лечения болезни паркинсона - Google Patents
Пролекарства карбидопа и l-dopa и их применение для лечения болезни паркинсона Download PDFInfo
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- RU2743347C2 RU2743347C2 RU2017117413A RU2017117413A RU2743347C2 RU 2743347 C2 RU2743347 C2 RU 2743347C2 RU 2017117413 A RU2017117413 A RU 2017117413A RU 2017117413 A RU2017117413 A RU 2017117413A RU 2743347 C2 RU2743347 C2 RU 2743347C2
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- compound
- formula
- pharmaceutically acceptable
- dopa
- carbidopa
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- 208000018737 Parkinson disease Diseases 0.000 title claims abstract description 53
- WTDRDQBEARUVNC-LURJTMIESA-N L-DOPA Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-LURJTMIESA-N 0.000 title abstract description 327
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 title abstract description 327
- TZFNLOMSOLWIDK-JTQLQIEISA-N carbidopa (anhydrous) Chemical compound NN[C@@](C(O)=O)(C)CC1=CC=C(O)C(O)=C1 TZFNLOMSOLWIDK-JTQLQIEISA-N 0.000 title abstract description 323
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| RS58972B1 (sr) | 2014-10-21 | 2019-08-30 | Abbvie Inc | Karbidopa i l-dopa prolekovi i njihova primena za lečenje parkinsonove bolesti |
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| MX2020005366A (es) | 2017-11-24 | 2020-08-13 | H Lundbeck As | Nuevos profarmacos de catecolamina para uso en el tratamiento de la enfermedad de parkinson. |
| CN110294789A (zh) * | 2018-03-21 | 2019-10-01 | 海南大学 | 含多巴寡肽的合成方法及其在抗帕金森病前药方面的应用 |
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| CN113727712B (zh) | 2019-05-21 | 2024-11-15 | H.隆德贝克有限公司 | 用于治疗帕金森病的儿茶酚胺氨基甲酸酯前药 |
| CN113677675B (zh) | 2019-05-21 | 2024-07-26 | H.隆德贝克有限公司 | 用于治疗帕金森病的新儿茶酚胺前药 |
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| US11844754B2 (en) | 2020-11-17 | 2023-12-19 | Neuroderm, Ltd. | Methods for treatment of Parkinson's disease |
| US11331293B1 (en) | 2020-11-17 | 2022-05-17 | Neuroderm, Ltd. | Method for treatment of Parkinson's disease |
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| EP4223288B1 (en) | 2022-02-07 | 2024-03-06 | Berlirem GmbH | Novel kit of pharmaceutical preparations for the treatment of parkinson's disease |
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| EP0393781A2 (en) * | 1989-04-20 | 1990-10-24 | ZAMBON GROUP S.p.A. | Dopamine pro-drug |
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