RU2726777C2 - Селективные соединения пептида yy и их применения - Google Patents
Селективные соединения пептида yy и их применения Download PDFInfo
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- RU2726777C2 RU2726777C2 RU2017145348A RU2017145348A RU2726777C2 RU 2726777 C2 RU2726777 C2 RU 2726777C2 RU 2017145348 A RU2017145348 A RU 2017145348A RU 2017145348 A RU2017145348 A RU 2017145348A RU 2726777 C2 RU2726777 C2 RU 2726777C2
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- Prior art keywords
- ethoxy
- carboxy
- amino
- butanoyl
- hpyy
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- A61P19/00—Drugs for skeletal disorders
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
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| SMT201800491T1 (it) | 2012-03-22 | 2018-11-09 | Novo Nordisk As | Composizioni di peptidi glp-1 e relativa preparazione |
| ES2688462T3 (es) | 2013-05-02 | 2018-11-02 | Novo Nordisk A/S | Dosificación oral de compuestos de GLP-1 |
| US10583172B2 (en) | 2013-11-15 | 2020-03-10 | Novo Nordisk A/S | HPYY(1-36) having a beta-homoarginine substitution at position 35 |
| JP6602760B2 (ja) * | 2013-11-15 | 2019-11-06 | ノヴォ ノルディスク アー／エス | 選択的なｐｙｙ化合物及びその使用 |
| US11229229B2 (en) | 2016-06-14 | 2022-01-25 | Purecircle Usa Inc. | Steviol glycosides compositions, production methods and uses |
| EP3746111B1 (en) | 2018-02-02 | 2023-07-19 | Novo Nordisk A/S | Solid compositions comprising a glp-1 agonist, a salt of n-(8-(2-hydroxybenzoyl)amino)caprylic acid and a lubricant |
| TWI749381B (zh) | 2018-11-01 | 2021-12-11 | 美商美國禮來大藥廠 | 蛋白質酪胺酸-酪胺酸類似物及其使用方法 |
| CN116726361A (zh) | 2018-11-19 | 2023-09-12 | 比奥拉治疗股份有限公司 | 用生物治疗剂治疗疾病的方法和装置 |
| JP2022543826A (ja) * | 2019-08-07 | 2022-10-14 | ノヴォ ノルディスク アー／エス | Ｐｙｙ化合物とｎ－（８－（２－ヒドロキシベンゾイル）アミノ）カプリル酸の塩とを含む固形組成物 |
| PH12022551101A1 (en) | 2019-11-11 | 2023-11-13 | Boehringer Ingelheim Int | Npy2 receptor agonists |
| US11707610B2 (en) | 2019-12-13 | 2023-07-25 | Biora Therapeutics, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
| WO2022029231A1 (en) * | 2020-08-07 | 2022-02-10 | Boehringer Ingelheim International Gmbh | Soluble npy2 receptor agonists |
| CN116745310A (zh) * | 2020-11-09 | 2023-09-12 | 艾巴克生物科技有限公司 | 化合物及其在治疗速激肽受体介导的病症中的用途 |
| IL304214B2 (en) | 2021-01-20 | 2025-01-01 | Viking Therapeutics Inc | Compositions and methods for treating metabolic and liver disorders |
| KR102873595B1 (ko) | 2021-09-15 | 2025-10-22 | 바이킹 테라퓨틱스 인코포레이티드 | 대사 및 간 장애의 치료를 위한 조성물 및 방법 |
| EP4299057A1 (en) | 2022-06-30 | 2024-01-03 | Adocia | Solid compositions comprising a peptide or a protein and an acylated amino acid |
| EP4180060A1 (en) | 2021-11-15 | 2023-05-17 | Adocia | Solid compositions comprising a peptide or a protein and an acylated amino acid |
| US20250000948A1 (en) | 2021-11-15 | 2025-01-02 | Adocia | Solid compositions comprising a peptide or a protein and an acylated amino acid |
| EP4299052A1 (en) | 2022-06-30 | 2024-01-03 | Adocia | Solid compositions comprising a peptide or a protein and a permeation enhancer |
| EP4299071A1 (en) | 2022-07-01 | 2024-01-03 | Adocia | Compositions comprising a peptide or a protein and an acylated amino acid |
| JP2025526148A (ja) | 2022-08-18 | 2025-08-07 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 長時間作用型ｇｌｐ－１／グルカゴン受容体アゴニスト及びｎｐｙ２受容体アゴニストを含む組合せ治療 |
| CN115960258B (zh) * | 2022-09-30 | 2024-01-12 | 广西医科大学附属肿瘤医院 | 一类GLP-1/glucagon/Y2受体三重激动剂及其应用 |
| WO2025128626A1 (en) * | 2023-12-12 | 2025-06-19 | Carmot Therapeutics, Inc. | Hybrid peptide compounds having a modified lysine residue |
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- 2016-06-13 TW TW105118511A patent/TWI694082B/zh not_active IP Right Cessation
- 2016-06-13 BR BR112017025108A patent/BR112017025108A2/pt not_active Application Discontinuation
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- 2016-06-13 MX MX2017015105A patent/MX392572B/es unknown
- 2016-06-13 KR KR1020177037622A patent/KR102476550B1/ko active Active
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- 2016-06-13 MY MYPI2017704318A patent/MY187047A/en unknown
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- 2017-11-20 IL IL255781A patent/IL255781B/en unknown
- 2017-11-30 SA SA517390445A patent/SA517390445B1/ar unknown
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| MX2017015105A (es) | 2018-05-07 |
| EP3307768A1 (en) | 2018-04-18 |
| ZA201707782B (en) | 2019-08-28 |
| CA2988500A1 (en) | 2016-12-15 |
| TW201710284A (zh) | 2017-03-16 |
| EP3307768C0 (en) | 2025-01-29 |
| SA517390445B1 (ar) | 2020-12-21 |
| US10005824B2 (en) | 2018-06-26 |
| IL255781B (en) | 2021-10-31 |
| RU2017145348A (ru) | 2019-07-12 |
| EP3307768B1 (en) | 2025-01-29 |
| JP6731958B2 (ja) | 2020-07-29 |
| MA43205A (fr) | 2018-09-19 |
| BR112017025108A2 (pt) | 2018-07-31 |
| AU2016275735A1 (en) | 2017-12-07 |
| KR102476550B1 (ko) | 2022-12-13 |
| CN107849110A (zh) | 2018-03-27 |
| JP2018522843A (ja) | 2018-08-16 |
| AR104984A1 (es) | 2017-08-30 |
| RU2017145348A3 (OSRAM) | 2019-09-09 |
| TWI694082B (zh) | 2020-05-21 |
| US20170313750A1 (en) | 2017-11-02 |
| IL255781A (en) | 2018-04-30 |
| MY187047A (en) | 2021-08-27 |
| CN107849110B (zh) | 2021-11-26 |
| KR20180019616A (ko) | 2018-02-26 |
| ES3019234T3 (en) | 2025-05-20 |
| AU2016275735B2 (en) | 2020-02-06 |
| MX392572B (es) | 2025-03-24 |
| WO2016198682A1 (en) | 2016-12-15 |
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