RU2724190C2 - Способы лечения болезни альцгеймера - Google Patents

Способы лечения болезни альцгеймера Download PDF

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RU2724190C2
RU2724190C2 RU2016136081A RU2016136081A RU2724190C2 RU 2724190 C2 RU2724190 C2 RU 2724190C2 RU 2016136081 A RU2016136081 A RU 2016136081A RU 2016136081 A RU2016136081 A RU 2016136081A RU 2724190 C2 RU2724190 C2 RU 2724190C2
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antibody
present
patient
antibodies
disease
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RU2016136081A
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Russian (ru)
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RU2016136081A (ru
RU2016136081A3 (cg-RX-API-DMAC7.html
Inventor
Уилльям ЧО
Мишель ФРИЗЕНХАН
Роберт ПОЛ
Майкл Уорд
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Дженентек, Инк.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU2016136081A 2014-02-08 2015-02-06 Способы лечения болезни альцгеймера RU2724190C2 (ru)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201461937472P 2014-02-08 2014-02-08
US61/937,472 2014-02-08
US201461971479P 2014-03-27 2014-03-27
US61/971,479 2014-03-27
US201462010259P 2014-06-10 2014-06-10
US62/010,259 2014-06-10
US201462081992P 2014-11-19 2014-11-19
US62/081,992 2014-11-19
PCT/US2015/014758 WO2015120233A1 (en) 2014-02-08 2015-02-06 Methods of treating alzheimer's disease

Publications (3)

Publication Number Publication Date
RU2016136081A RU2016136081A (ru) 2018-03-13
RU2016136081A3 RU2016136081A3 (cg-RX-API-DMAC7.html) 2018-09-28
RU2724190C2 true RU2724190C2 (ru) 2020-06-23

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RU2016136081A RU2724190C2 (ru) 2014-02-08 2015-02-06 Способы лечения болезни альцгеймера

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US (3) US20150246963A1 (cg-RX-API-DMAC7.html)
EP (2) EP3102231B1 (cg-RX-API-DMAC7.html)
JP (4) JP6685912B2 (cg-RX-API-DMAC7.html)
KR (4) KR20160111039A (cg-RX-API-DMAC7.html)
CN (1) CN106163548A (cg-RX-API-DMAC7.html)
AU (1) AU2015214058B2 (cg-RX-API-DMAC7.html)
BR (1) BR112016018170A2 (cg-RX-API-DMAC7.html)
CA (1) CA2938466C (cg-RX-API-DMAC7.html)
CL (2) CL2016001979A1 (cg-RX-API-DMAC7.html)
HK (1) HK1231401A1 (cg-RX-API-DMAC7.html)
IL (1) IL246999B (cg-RX-API-DMAC7.html)
MX (1) MX380252B (cg-RX-API-DMAC7.html)
MY (1) MY179105A (cg-RX-API-DMAC7.html)
NZ (1) NZ723884A (cg-RX-API-DMAC7.html)
RU (1) RU2724190C2 (cg-RX-API-DMAC7.html)
SG (2) SG11201606316XA (cg-RX-API-DMAC7.html)
TW (1) TWI705824B (cg-RX-API-DMAC7.html)
WO (1) WO2015120233A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201605341B (cg-RX-API-DMAC7.html)

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ES2952727T3 (es) * 2015-09-10 2023-11-03 Alzheon Inc Tratamiento de la enfermedad de Alzheimer en una población de pacientes particular
EP3368563A1 (en) 2015-10-28 2018-09-05 The Trustees Of The University Of Pennsylvania Intrathecal administration of adeno-associated-viral vectors for gene therapy
CA3011739A1 (en) * 2016-01-20 2017-07-27 Genentech, Inc. High dose treatments for alzheimer's disease
KR20190021311A (ko) * 2016-06-07 2019-03-05 바이오겐 인터내셔널 뉴로사이언스 게엠베하 알츠하이머병의 치료 방법
CA3032289A1 (en) * 2016-07-29 2018-02-01 Biogen Chesapeake Llc Methods of treating or preventing amyloid related imaging abnormalities associated with alzheimer's disease treatment
IT201600118499A1 (it) * 2016-11-25 2018-05-25 Giacomo Koch Uso di agonisti dopaminergici per la prevenzione della progressione della malattia di Alzheimer allo stadio precoce.
US12290516B2 (en) 2017-05-12 2025-05-06 The Hong Kong University Of Science And Technology Heterocyclic compounds as EphA4 inhibitors
MA49947B1 (fr) 2017-08-22 2023-03-31 Biogen Ma Inc Compositions pharmaceutiques contenant des anticorps anti-bêta-amyloïdes
WO2019182319A1 (ko) * 2018-03-20 2019-09-26 (주)인벤티지랩 인지 장애 관련 질병의 예방 또는 치료용 약학적 조성물의 제조 방법 및 이의 제조 방법으로 제조된 인지 장애 관련 질병의 예방 또는 치료용 약학적 조성물
KR102224918B1 (ko) 2018-03-20 2021-03-09 (주)인벤티지랩 도네페질 및 메만틴을 포함하는 인지 장애 관련 질병의 예방 또는 치료용 약학적 복합 조성물 및 이의 제조 방법
WO2019195761A2 (en) * 2018-04-05 2019-10-10 Calasia Pharmaceuticals, Inc. Pharmacological agents for treating ocular diseases
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