RU2683793C2 - Замещенные аминопиримидиновые соединения и способы их использования - Google Patents

Замещенные аминопиримидиновые соединения и способы их использования Download PDF

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RU2683793C2
RU2683793C2 RU2016115082A RU2016115082A RU2683793C2 RU 2683793 C2 RU2683793 C2 RU 2683793C2 RU 2016115082 A RU2016115082 A RU 2016115082A RU 2016115082 A RU2016115082 A RU 2016115082A RU 2683793 C2 RU2683793 C2 RU 2683793C2
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compound
alkylene
compounds
pharmaceutically acceptable
kinase
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RU2016115082A
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Russian (ru)
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RU2016115082A3 (enExample
RU2016115082A (ru
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Нин Си
Лян ВАН
Тинцзинь ВАН
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Калитор Сайенсез, ЛЛС
Саншайн Лейк Фарма Ко., Лтд.
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    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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RU2016115082A 2013-09-22 2014-09-17 Замещенные аминопиримидиновые соединения и способы их использования RU2683793C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361880974P 2013-09-22 2013-09-22
US61/880,974 2013-09-22
US201461983444P 2014-04-23 2014-04-23
US61/983,444 2014-04-23
PCT/US2014/055967 WO2015042078A2 (en) 2013-09-22 2014-09-17 Substituted aminopyrimidine compounds and methods of use

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RU2016115082A RU2016115082A (ru) 2017-10-25
RU2016115082A3 RU2016115082A3 (enExample) 2018-07-25
RU2683793C2 true RU2683793C2 (ru) 2019-04-02

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RU2016114866A RU2675105C9 (ru) 2013-09-22 2014-09-17 Замещенные аминопиримидиновые соединения и способы их использования

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US (4) US9670194B2 (enExample)
EP (2) EP3046921A4 (enExample)
JP (2) JP6494633B2 (enExample)
KR (2) KR20160060100A (enExample)
AU (2) AU2014321420B2 (enExample)
BR (1) BR112016003229A8 (enExample)
CA (2) CA2918938C (enExample)
MX (2) MX2016003456A (enExample)
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RU (2) RU2683793C2 (enExample)
SG (2) SG11201600028YA (enExample)
WO (3) WO2015042078A2 (enExample)

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CA2918938C (en) * 2013-09-22 2021-05-18 Calitor Sciences, Llc Substituted aminopyrimidine compounds and methods of use
JP6455995B2 (ja) * 2014-06-13 2019-01-23 ギリアード サイエンシーズ， インコーポレイテッド ホスファチジルイノシトール３−キナーゼ阻害剤
EP3154969B1 (en) 2014-06-13 2019-10-09 Gilead Sciences, Inc. Phosphatidylinositol 3-kinase inhibitors
ES2833025T3 (es) 2014-06-13 2021-06-14 Gilead Sciences Inc Inhibidores de fosfatidilinositol 3-quinasa
KR20170015508A (ko) 2014-06-13 2017-02-08 길리애드 사이언시즈, 인코포레이티드 포스파티딜이노시톨 3-키나제 억제제로서의 퀴나졸리논 유도체
MA40250A (fr) 2014-07-04 2017-05-10 Lupin Ltd Dérivés de quinolizinone utilisés comme inhibiteurs de pi3k
CN105924433B (zh) * 2015-02-28 2020-12-22 广东东阳光药业有限公司 取代的氨基嘧啶类化合物及其使用方法和用途
WO2016149160A1 (en) * 2015-03-15 2016-09-22 Sunshine Lake Pharma Co., Ltd. Substituted aminopyrimidine compounds and methods of use
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