RU2633488C2 - Способ определения свободного связывающего партнера мультиспецифичного связующего - Google Patents
Способ определения свободного связывающего партнера мультиспецифичного связующего Download PDFInfo
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
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- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
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Applications Claiming Priority (3)
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| EP11194350 | 2011-12-19 | ||
| EP11194350.2 | 2011-12-19 | ||
| PCT/EP2012/075991 WO2013092611A2 (en) | 2011-12-19 | 2012-12-18 | Method for the detection of free binding partner of a multispecific binder |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2014128510A RU2014128510A (ru) | 2016-02-10 |
| RU2633488C2 true RU2633488C2 (ru) | 2017-10-12 |
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| EP (1) | EP2795335B1 (cg-RX-API-DMAC7.html) |
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| BR (1) | BR112014011535A2 (cg-RX-API-DMAC7.html) |
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| WO (1) | WO2013092611A2 (cg-RX-API-DMAC7.html) |
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| US8956859B1 (en) | 2010-08-13 | 2015-02-17 | Aviex Technologies Llc | Compositions and methods for determining successful immunization by one or more vaccines |
| CN104105966B (zh) | 2012-02-01 | 2016-10-26 | 弗·哈夫曼-拉罗切有限公司 | 用于检测多特异性结合物的结合搭档的方法 |
| BR112015000665A2 (pt) | 2012-07-13 | 2017-06-27 | Hoffmann La Roche | método para a determinação da quantidade de um anticorpo |
| CA2926306C (en) * | 2013-11-05 | 2022-12-06 | F. Hoffmann-La Roche Ag | A method for determining the total amount and/or concentration of an analyte in a sample |
| WO2015143277A1 (en) * | 2014-03-20 | 2015-09-24 | Wellstat Diagnostics, Llc | Antibodies and methods for the detection of cell death |
| ES2761427T3 (es) | 2014-12-18 | 2020-05-19 | Hoffmann La Roche | Procedimientos para reducir interferencias |
| AU2018304711B2 (en) | 2017-07-20 | 2025-04-10 | Cytomx Therapeutics, Inc. | Methods of qualitatively and/or quantitatively analyzing properties of activatable antibodies and uses thereof |
| CN109358192B (zh) * | 2018-02-08 | 2020-05-12 | 中国科学院上海药物研究所 | 一种去除抗药抗体检测样品中游离药物的装置和方法、该装置的制备方法及应用 |
| EP3805757A4 (en) | 2018-06-04 | 2022-03-23 | Chugai Seiyaku Kabushiki Kaisha | Method for detecting complex |
| WO2020229378A1 (en) * | 2019-05-13 | 2020-11-19 | F. Hoffmann-La Roche Ag | Interference-suppressed pharmacokinetic immunoassay |
| KR20220007586A (ko) * | 2019-05-13 | 2022-01-18 | 리제너론 파마슈티칼스 인코포레이티드 | 개선된 경쟁적 리간드 결합 검정 |
| CN117805397A (zh) * | 2024-02-29 | 2024-04-02 | 军科正源（北京）药物研究有限责任公司 | 检测游离vegf的方法 |
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| EP1653233A1 (en) * | 2004-10-30 | 2006-05-03 | Roche Diagnostics GmbH | Method for determining antibodies of a particular class using an immune complex-specific antibody |
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-
2012
- 2012-12-18 CA CA2853917A patent/CA2853917A1/en not_active Abandoned
- 2012-12-18 KR KR1020147016700A patent/KR20140099277A/ko not_active Ceased
- 2012-12-18 JP JP2014547933A patent/JP6203747B2/ja active Active
- 2012-12-18 MX MX2014007095A patent/MX349003B/es active IP Right Grant
- 2012-12-18 RU RU2014128510A patent/RU2633488C2/ru not_active IP Right Cessation
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- 2012-12-18 BR BR112014011535A patent/BR112014011535A2/pt not_active Application Discontinuation
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- 2012-12-18 WO PCT/EP2012/075991 patent/WO2013092611A2/en not_active Ceased
-
2014
- 2014-06-18 US US14/308,539 patent/US9671394B2/en active Active
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| WO1995004931A1 (en) * | 1993-08-06 | 1995-02-16 | Surface Active Limited | Diagnostic method |
| US20040191794A1 (en) * | 2001-08-28 | 2004-09-30 | Kurt Weindel | Method for the determination of multiple analytes |
| EP1653233A1 (en) * | 2004-10-30 | 2006-05-03 | Roche Diagnostics GmbH | Method for determining antibodies of a particular class using an immune complex-specific antibody |
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Also Published As
| Publication number | Publication date |
|---|---|
| EP2795335A2 (en) | 2014-10-29 |
| BR112014011535A2 (pt) | 2017-05-09 |
| CA2853917A1 (en) | 2013-06-27 |
| JP2015502547A (ja) | 2015-01-22 |
| KR20140099277A (ko) | 2014-08-11 |
| WO2013092611A3 (en) | 2013-10-17 |
| CN104040350B (zh) | 2016-05-18 |
| CN104040350A (zh) | 2014-09-10 |
| MX2014007095A (es) | 2014-07-22 |
| MX349003B (es) | 2017-07-06 |
| RU2014128510A (ru) | 2016-02-10 |
| US20150072359A1 (en) | 2015-03-12 |
| WO2013092611A2 (en) | 2013-06-27 |
| US9671394B2 (en) | 2017-06-06 |
| HK1201920A1 (zh) | 2015-09-11 |
| JP6203747B2 (ja) | 2017-09-27 |
| EP2795335B1 (en) | 2017-09-06 |
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| MM4A | The patent is invalid due to non-payment of fees |
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