RU2608611C2 - СОЕДИНЕНИЯ ИМИДАЗО[1,2-а] ПИРИДИНА, ИХ СИНТЕЗ И СПОСОБЫ ПРИМЕНЕНИЯ - Google Patents

СОЕДИНЕНИЯ ИМИДАЗО[1,2-а] ПИРИДИНА, ИХ СИНТЕЗ И СПОСОБЫ ПРИМЕНЕНИЯ Download PDF

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RU2608611C2
RU2608611C2 RU2012122653A RU2012122653A RU2608611C2 RU 2608611 C2 RU2608611 C2 RU 2608611C2 RU 2012122653 A RU2012122653 A RU 2012122653A RU 2012122653 A RU2012122653 A RU 2012122653A RU 2608611 C2 RU2608611 C2 RU 2608611C2
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substituted
halogen
phenyl
carbon atoms
compound
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RU2012122653A
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RU2012122653A (ru
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Марвин Дж. МИЛЛЕР
Гаррет К. МОРАСКИ
Лоувелл Д. МАРКЛИ
Джордж Э. ДЭВИС
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Юниверсити Оф Нотр Дам Дю Лак
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pulmonology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
RU2012122653A 2009-11-05 2010-11-05 СОЕДИНЕНИЯ ИМИДАЗО[1,2-а] ПИРИДИНА, ИХ СИНТЕЗ И СПОСОБЫ ПРИМЕНЕНИЯ RU2608611C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25854909P 2009-11-05 2009-11-05
US61/258,549 2009-11-05
PCT/US2010/055728 WO2011057145A2 (en) 2009-11-05 2010-11-05 Imidazo[1,2-a] pyridine compounds, synthesis thereof, and methods of using same

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RU2012122653A RU2012122653A (ru) 2013-12-10
RU2608611C2 true RU2608611C2 (ru) 2017-01-23

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US (3) US9309238B2 (enExample)
EP (2) EP2496578A4 (enExample)
CN (3) CN110483499A (enExample)
BR (1) BR112012010752B1 (enExample)
HK (1) HK1248676A1 (enExample)
IL (1) IL219564A (enExample)
IN (1) IN2012DN04917A (enExample)
RU (1) RU2608611C2 (enExample)
WO (1) WO2011057145A2 (enExample)
ZA (1) ZA201204028B (enExample)

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RU2785345C1 (ru) * 2022-02-28 2022-12-06 Федеральное государственное автономное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет" Применение 1-(2-гидрокси-5-хлорфенил)-4-фенил-6-тиоксо-5,6-дигидро-1H-пирроло[3,2-c]пиридин-2,3-диона в качестве средства, обладающего противомикробной активностью
US12522584B2 (en) 2020-06-02 2026-01-13 Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd 3,4-dihydroisoquinoline compound and use thereof

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WO2015014993A2 (en) * 2013-08-02 2015-02-05 Institut Pasteur Korea Anti-infective compounds
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CN103965193B (zh) * 2014-05-30 2016-04-06 浙江司太立制药股份有限公司 N-(苯氧烷基)咪唑并[1,2-a]吡啶-3-酰胺类化合物及其制备方法
CN104628721A (zh) * 2015-01-22 2015-05-20 湖南华腾制药有限公司 一种咪唑并[1,2-a]吡啶衍生物的制备方法
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MA45377A (fr) 2016-06-16 2019-04-24 Janssen Sciences Ireland Unlimited Co Composés hétérocycliques en tant qu'agents antibacteriens
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CN106588916A (zh) * 2016-11-21 2017-04-26 浙江司太立制药股份有限公司 N‑(苯氧乙基)咪唑并[1,2‑a]吡啶‑3‑酰胺类化合物及其制备方法
JP2020502110A (ja) * 2016-12-16 2020-01-23 バイエル・アクチエンゲゼルシヤフト 殺虫剤として使用するためのメソイオン性イミダゾピリジン類
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CN108159049B (zh) * 2018-02-01 2021-01-05 中国科学院广州生物医药与健康研究院 一种吡啶类化合物的新用途
WO2019175737A1 (en) * 2018-03-12 2019-09-19 University Of Notre Dame Du Lac Deuterated imidazopyridines
CN110759913B (zh) * 2018-07-26 2022-01-28 南开大学 吲哚酰腙衍生物及其制备方法和在防治植物病毒、杀菌、杀虫方面的应用
CN111662283B (zh) * 2019-03-07 2021-11-16 湖南化工研究院有限公司 咪唑并吡啶类化合物及其中间体、制备方法与应用
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RU2825312C1 (ru) * 2020-06-02 2024-08-23 СиЭсПиСи ЧЖУНЦИ ФАРМАСЬЮТИКАЛ ТЕКНОЛОДЖИ (ШИЦЗЯЧЖУАН) КО., ЛТД Соединение 3,4-дигидроизохинолина и его применение
US12522584B2 (en) 2020-06-02 2026-01-13 Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd 3,4-dihydroisoquinoline compound and use thereof
RU2785345C1 (ru) * 2022-02-28 2022-12-06 Федеральное государственное автономное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет" Применение 1-(2-гидрокси-5-хлорфенил)-4-фенил-6-тиоксо-5,6-дигидро-1H-пирроло[3,2-c]пиридин-2,3-диона в качестве средства, обладающего противомикробной активностью

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IL219564A0 (en) 2012-06-28
US20120220457A1 (en) 2012-08-30
CN102762556A (zh) 2012-10-31
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EP2496578A2 (en) 2012-09-12
IL219564A (en) 2017-01-31
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CN102762556B (zh) 2017-04-26
BR112012010752A2 (pt) 2020-09-15
WO2011057145A2 (en) 2011-05-12
US10913737B2 (en) 2021-02-09
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US9908876B2 (en) 2018-03-06
HK1248676A1 (en) 2018-10-19
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US20180354944A1 (en) 2018-12-13
BR112012010752B1 (pt) 2021-07-20

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