RU2531548C2 - Композиция для лечения заболевания - Google Patents

Композиция для лечения заболевания Download PDF

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Publication number
RU2531548C2
RU2531548C2 RU2011117293/10A RU2011117293A RU2531548C2 RU 2531548 C2 RU2531548 C2 RU 2531548C2 RU 2011117293/10 A RU2011117293/10 A RU 2011117293/10A RU 2011117293 A RU2011117293 A RU 2011117293A RU 2531548 C2 RU2531548 C2 RU 2531548C2
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RU
Russia
Prior art keywords
antibody
domain
humanized anti
chain
patient
Prior art date
Application number
RU2011117293/10A
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English (en)
Russian (ru)
Other versions
RU2011117293A (ru
Inventor
Франк ОСТЕРРОТ
Зильке АЙГНЕР
Кристоф УЭРЕК
Андреа ВАРТЕНБЕРГ-ДЕМАНД
Анатолий РУДНЕВ
Михаэль ЗОЛЬДАН
Кристоф БРЮХЕР
Бенжамин ДЕЛКЕН
Шанталь ЦУБЕР
Грегор ШУЛЬЦ
Никлас ЧЕЛОТ
Original Assignee
Биотест Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0817809A external-priority patent/GB0817809D0/en
Priority claimed from GB0817811A external-priority patent/GB0817811D0/en
Priority claimed from GB0817810A external-priority patent/GB0817810D0/en
Priority claimed from PCT/EP2009/052811 external-priority patent/WO2009124815A1/en
Priority claimed from PCT/EP2009/052810 external-priority patent/WO2009112502A1/en
Priority claimed from PCT/EP2009/052809 external-priority patent/WO2009121690A1/en
Application filed by Биотест Аг filed Critical Биотест Аг
Publication of RU2011117293A publication Critical patent/RU2011117293A/ru
Application granted granted Critical
Publication of RU2531548C2 publication Critical patent/RU2531548C2/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2812—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
RU2011117293/10A 2008-09-29 2009-08-31 Композиция для лечения заболевания RU2531548C2 (ru)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
GB0817809A GB0817809D0 (en) 2008-09-29 2008-09-29 Agent for treating disease
GB0817811A GB0817811D0 (en) 2008-09-29 2008-09-29 Agent for treating disease
GB0817809.7 2008-09-29
GB0817810.5 2008-09-29
GB0817811.3 2008-09-29
GB0817810A GB0817810D0 (en) 2008-09-29 2008-09-29 Agent for treating disease
EPPCT/EP2009/052811 2009-03-10
EPPCT/EP2009/052810 2009-03-10
PCT/EP2009/052811 WO2009124815A1 (en) 2008-03-13 2009-03-10 Agent for treating disease
PCT/EP2009/052810 WO2009112502A1 (en) 2008-03-13 2009-03-10 Agent for treating disease
PCT/EP2009/052809 WO2009121690A1 (en) 2008-03-13 2009-03-10 Agent for treating disease
EPPCT/EP2009/052809 2009-03-10
PCT/EP2009/061210 WO2010034590A1 (en) 2008-09-29 2009-08-31 Composition for treating disease

Publications (2)

Publication Number Publication Date
RU2011117293A RU2011117293A (ru) 2012-11-10
RU2531548C2 true RU2531548C2 (ru) 2014-10-20

Family

ID=41138980

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2011117293/10A RU2531548C2 (ru) 2008-09-29 2009-08-31 Композиция для лечения заболевания

Country Status (16)

Country Link
US (1) US20110229465A1 (enExample)
JP (2) JP2012504110A (enExample)
KR (1) KR20110061630A (enExample)
CN (1) CN102215867B (enExample)
AU (1) AU2009296078B2 (enExample)
BR (1) BRPI0919489A2 (enExample)
CA (1) CA2738598C (enExample)
CR (1) CR20110226A (enExample)
DK (1) DK2341937T3 (enExample)
ES (1) ES2528419T3 (enExample)
IL (1) IL211904A (enExample)
MX (1) MX2011003335A (enExample)
PT (1) PT2341937E (enExample)
RU (1) RU2531548C2 (enExample)
SG (1) SG194362A1 (enExample)
WO (1) WO2010034590A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1460088A1 (en) 2003-03-21 2004-09-22 Biotest AG Humanized anti-CD4 antibody with immunosuppressive properties
CN102027017A (zh) * 2008-03-13 2011-04-20 生物测试股份公司 一种治疗疾病的试剂
PL2262838T3 (pl) * 2008-03-13 2016-10-31 Środek do leczenia choroby
AU2009224690B2 (en) * 2008-03-13 2014-10-09 Biotest Ag Agent for treating disease
GB0920944D0 (en) * 2009-11-30 2010-01-13 Biotest Ag Agents for treating disease
US20160158352A1 (en) * 2013-07-10 2016-06-09 The United States of America, as represented by the Secretary, Department of Health & Human Servic Apoptotic cell-mediated induction of antigen specific regulatory t-cells for the therapy of autoimmune diseases in animals and humans
GB202017681D0 (en) * 2020-11-09 2020-12-23 T Balance Therapeutics Gmbh Anti-CD4 antibody or fragment thereof for medical use
DE102020129648A1 (de) * 2020-11-10 2022-05-12 Leopold MTX GmbH Pharmazeutische zusammensetzung

Citations (2)

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EP1460088A1 (en) * 2003-03-21 2004-09-22 Biotest AG Humanized anti-CD4 antibody with immunosuppressive properties
RU2316337C2 (ru) * 2001-04-24 2008-02-10 Мерк Патент Гмбх КОМБИНИРОВАННАЯ ТЕРАПИЯ, ИСПОЛЬЗУЮЩАЯ АНТИАНГИОГЕННЫЕ СРЕДСТВА И TNF-α

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Also Published As

Publication number Publication date
JP2012504110A (ja) 2012-02-16
KR20110061630A (ko) 2011-06-09
US20110229465A1 (en) 2011-09-22
SG194362A1 (en) 2013-11-29
WO2010034590A1 (en) 2010-04-01
CN102215867A (zh) 2011-10-12
JP6154847B2 (ja) 2017-06-28
BRPI0919489A2 (pt) 2015-12-01
JP2015172060A (ja) 2015-10-01
DK2341937T3 (en) 2015-02-09
CA2738598C (en) 2017-11-21
CN102215867B (zh) 2017-04-19
AU2009296078B2 (en) 2015-08-20
CA2738598A1 (en) 2010-04-01
CR20110226A (es) 2011-12-05
AU2009296078A1 (en) 2010-04-01
PT2341937E (pt) 2015-02-18
HK1154797A1 (en) 2012-05-04
RU2011117293A (ru) 2012-11-10
ES2528419T3 (es) 2015-02-09
MX2011003335A (es) 2011-04-27
IL211904A0 (en) 2011-06-30
IL211904A (en) 2016-03-31

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Effective date: 20190901