RU2530899C2 - Противомалярийные соединения - Google Patents
Противомалярийные соединения Download PDFInfo
- Publication number
- RU2530899C2 RU2530899C2 RU2011107295/04A RU2011107295A RU2530899C2 RU 2530899 C2 RU2530899 C2 RU 2530899C2 RU 2011107295/04 A RU2011107295/04 A RU 2011107295/04A RU 2011107295 A RU2011107295 A RU 2011107295A RU 2530899 C2 RU2530899 C2 RU 2530899C2
- Authority
- RU
- Russia
- Prior art keywords
- independently represents
- independently
- compound
- pharmaceutically acceptable
- halogen
- Prior art date
Links
- 0 *1c(cccc2)c2-c2ccccc12 Chemical compound *1c(cccc2)c2-c2ccccc12 0.000 description 16
- ZPZYLIDWQYBZJA-UHFFFAOYSA-N COc(c(C(Nc1cc(C(F)(F)F)cc(NC(CCCCNC(N)=N)=O)c1SCCN)=O)c1)cc(OC)c1C(Nc1cc(C(F)(F)F)cc(NC(CCCCNC(N)=N)=O)c1SCCN)=O Chemical compound COc(c(C(Nc1cc(C(F)(F)F)cc(NC(CCCCNC(N)=N)=O)c1SCCN)=O)c1)cc(OC)c1C(Nc1cc(C(F)(F)F)cc(NC(CCCCNC(N)=N)=O)c1SCCN)=O ZPZYLIDWQYBZJA-UHFFFAOYSA-N 0.000 description 3
- WEAYCYAIVOIUMG-UHFFFAOYSA-N Cc(cc1)ccc1S(c1ccc(C)cc1)(=O)=O Chemical compound Cc(cc1)ccc1S(c1ccc(C)cc1)(=O)=O WEAYCYAIVOIUMG-UHFFFAOYSA-N 0.000 description 2
- IFUXNNNOWYYJLS-UHFFFAOYSA-N NC(NCCCCC(Nc1cc(C(F)(F)F)cc(NC(CNc(cc2)ccc2NC(Nc(cc(C(F)(F)F)cc2NC(CCCCNC(N)=N)=O)c2OC2CNCC2)=O)=O)c1OC1CNCC1)=O)=N Chemical compound NC(NCCCCC(Nc1cc(C(F)(F)F)cc(NC(CNc(cc2)ccc2NC(Nc(cc(C(F)(F)F)cc2NC(CCCCNC(N)=N)=O)c2OC2CNCC2)=O)=O)c1OC1CNCC1)=O)=N IFUXNNNOWYYJLS-UHFFFAOYSA-N 0.000 description 2
- KHJCQGNBCSDZGH-UHFFFAOYSA-N NCCSc(c(NC(CCCCNC(N)=N)=O)cc(C(F)(F)F)c1)c1NC(Nc(cc(C(F)(F)F)cc1NC(Nc(cc(C(F)(F)F)cc2NC(CCCCNC(N)=N)=O)c2SCCN)=O)c1SCCN)=O Chemical compound NCCSc(c(NC(CCCCNC(N)=N)=O)cc(C(F)(F)F)c1)c1NC(Nc(cc(C(F)(F)F)cc1NC(Nc(cc(C(F)(F)F)cc2NC(CCCCNC(N)=N)=O)c2SCCN)=O)c1SCCN)=O KHJCQGNBCSDZGH-UHFFFAOYSA-N 0.000 description 2
- WAMZHBKBIDFKOI-UHFFFAOYSA-N CC(C)C(C=C1)=CC(C2)C1c(cc1)c2cc1SC Chemical compound CC(C)C(C=C1)=CC(C2)C1c(cc1)c2cc1SC WAMZHBKBIDFKOI-UHFFFAOYSA-N 0.000 description 1
- YHEVFOFMUUNVQV-UHFFFAOYSA-N CCSc(c(NC(c1c[nH]cn1)=O)c1)ccc1Br Chemical compound CCSc(c(NC(c1c[nH]cn1)=O)c1)ccc1Br YHEVFOFMUUNVQV-UHFFFAOYSA-N 0.000 description 1
- XKCNHZRWZXIFOX-UHFFFAOYSA-N NC(NCCCCC(Nc1cc(C(F)(F)F)cc(NC(Nc(cc2)ccc2NC(Nc(cc(C(F)(F)F)cc2NC(CCCCNC(N)=N)=O)c2OC2CNCC2)=O)=O)c1OC1CNCC1)=O)=N Chemical compound NC(NCCCCC(Nc1cc(C(F)(F)F)cc(NC(Nc(cc2)ccc2NC(Nc(cc(C(F)(F)F)cc2NC(CCCCNC(N)=N)=O)c2OC2CNCC2)=O)=O)c1OC1CNCC1)=O)=N XKCNHZRWZXIFOX-UHFFFAOYSA-N 0.000 description 1
- LMGXIBIHWBCDIA-XVNBXDOJSA-N NCCCCC(Nc1c(CSCCNC(N)=N)c(NC(c2ncnc(C(Nc3cc(C(F)(F)F)cc(NC(CCCCN)=O)c3/C=C/CCNC(N)=N)=O)c2)=O)cc(C(F)(F)F)c1)=O Chemical compound NCCCCC(Nc1c(CSCCNC(N)=N)c(NC(c2ncnc(C(Nc3cc(C(F)(F)F)cc(NC(CCCCN)=O)c3/C=C/CCNC(N)=N)=O)c2)=O)cc(C(F)(F)F)c1)=O LMGXIBIHWBCDIA-XVNBXDOJSA-N 0.000 description 1
- RQRXKXAMTYHLPW-UHFFFAOYSA-N NCCSc(ccc(Br)c1)c1NC=O Chemical compound NCCSc(ccc(Br)c1)c1NC=O RQRXKXAMTYHLPW-UHFFFAOYSA-N 0.000 description 1
- HCHBOCQSMHHVJO-UHFFFAOYSA-N NCCc1cccc(-c(cc2c3c4)ccc2[s]c3ccc4-c2cccc(CCN)c2)c1 Chemical compound NCCc1cccc(-c(cc2c3c4)ccc2[s]c3ccc4-c2cccc(CCN)c2)c1 HCHBOCQSMHHVJO-UHFFFAOYSA-N 0.000 description 1
- NHQDETIJWKXCTC-UHFFFAOYSA-N OOC(c1cc(Cl)ccc1)=O Chemical compound OOC(c1cc(Cl)ccc1)=O NHQDETIJWKXCTC-UHFFFAOYSA-N 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/78—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C217/80—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings
- C07C217/82—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring
- C07C217/90—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring the oxygen atom of at least one of the etherified hydroxy groups being further bound to a carbon atom of a six-membered aromatic ring, e.g. amino-diphenylethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C317/22—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/40—Y being a hydrogen or a carbon atom
- C07C323/42—Y being a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/43—Y being a hetero atom
- C07C323/44—X or Y being nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/76—Dibenzothiophenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/10—Dibenzothiopyrans; Hydrogenated dibenzothiopyrans
- C07D335/12—Thioxanthenes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8397208P | 2008-07-28 | 2008-07-28 | |
| US61/083,972 | 2008-07-28 | ||
| US16246709P | 2009-03-23 | 2009-03-23 | |
| US61/162,467 | 2009-03-23 | ||
| PCT/US2009/051909 WO2010014573A1 (en) | 2008-07-28 | 2009-07-28 | Anti-malarial compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2011107295A RU2011107295A (ru) | 2012-09-10 |
| RU2530899C2 true RU2530899C2 (ru) | 2014-10-20 |
Family
ID=41610687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2011107295/04A RU2530899C2 (ru) | 2008-07-28 | 2009-07-28 | Противомалярийные соединения |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US8796275B2 (enExample) |
| EP (1) | EP2321275A4 (enExample) |
| JP (1) | JP2011529502A (enExample) |
| KR (1) | KR20110063435A (enExample) |
| CN (1) | CN102164892A (enExample) |
| AU (1) | AU2009276744A1 (enExample) |
| BR (1) | BRPI0916649A2 (enExample) |
| CA (1) | CA2732572A1 (enExample) |
| IL (1) | IL210935A0 (enExample) |
| MX (1) | MX2011000971A (enExample) |
| RU (1) | RU2530899C2 (enExample) |
| WO (1) | WO2010014573A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090092574A1 (en) | 2006-12-29 | 2009-04-09 | Scott Richard W | Ophthalmic And Otic Compositions Of Facially Amphiphilic Polymers And Oligomers And Uses Thereof |
| TWI478915B (zh) | 2008-10-27 | 2015-04-01 | Cellceutix Corp | 宿主防禦之合成模擬物及其用途 |
| JP2013516470A (ja) * | 2010-01-07 | 2013-05-13 | ポリメディックス・インコーポレーテッド | 抗ヘパリン化合物 |
| AU2011276349A1 (en) * | 2010-07-07 | 2013-02-28 | Polymedix, Inc. | Methods of immune modulation |
| TW201208677A (en) * | 2010-08-21 | 2012-03-01 | Polymedix Inc | Facially amphiphilic compounds, compositions, and uses thereof in treating cancer |
| RU2453533C1 (ru) * | 2011-02-08 | 2012-06-20 | Государственное образовательное учреждение высшего профессионального образования "Ярославский государственный университет им. П.Г. Демидова" | Способ получения 1,3- и 1,4-бис(2-амино-4-(трифторметил)фенокси)бензола |
| DK2709619T3 (en) | 2011-05-16 | 2018-01-15 | Cellceutix Corp | RELATIONSHIPS FOR USING THE TREATMENT OF MUCOSITIS |
| AU2012352621A1 (en) | 2011-12-13 | 2014-07-24 | Cellceutix Corporation | Cyclic compounds and methods of making and using the same |
| EP2794565B1 (en) * | 2011-12-21 | 2017-07-26 | Novira Therapeutics Inc. | Hepatitis b antiviral agents |
| WO2013130738A1 (en) * | 2012-02-29 | 2013-09-06 | Polymedix, Inc. | Compounds and methods for treating malaria |
| KR102307287B1 (ko) * | 2013-08-30 | 2021-09-29 | 가부시키가이샤 한도오따이 에네루기 켄큐쇼 | 유기 화합물, 발광 소자, 발광 장치, 전자 기기, 및 조명 장치 |
| ES2894657T3 (es) * | 2017-07-04 | 2022-02-15 | Sanofi Sa | Compuestos de etinilo, su preparación y su uso terapéutico para el tratamiento de la malaria |
| US11771694B2 (en) | 2020-06-05 | 2023-10-03 | Innovation Pharmaceuticals Inc. | Arylamide compounds for treatment and prevention of viral infections |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU425905A1 (ru) * | 1972-07-27 | 1974-04-30 | Ю. А. Москвичев, Г. С. Миронов, М. И. Фарберов, | СПОСОБ ПОЛУЧЕНИЯ п,п'-БИС- |
| SU1121264A1 (ru) * | 1983-04-29 | 1984-10-30 | Московский ордена Ленина и ордена Трудового Красного Знамени химико-технологический институт им.Д.И.Менделеева | Способ получени 3,6-бис(диметиламино)тиоксантен-10,10-диоксида |
| RU2067572C1 (ru) * | 1994-02-04 | 1996-10-10 | Ярославский государственный технический университет | Многоядерные бисазиды |
| US6172104B1 (en) * | 1998-08-20 | 2001-01-09 | The University Of North Carolina At Chapel Hill | Dicationic dibenzofuran and dibenzothiophene compounds and methods of use thereof |
| WO2002064571A1 (en) * | 2001-02-14 | 2002-08-22 | Warner-Lambert Company Llc | Pyrimidine matrix metalloproteinase inhibitors |
| RU2296756C2 (ru) * | 2005-05-17 | 2007-04-10 | Федеральное унитарное государственное предприятие "Государственный научно-исследовательский институт биологического приборостроения" (ГосНИИ БП) | Комплексообразующие дибензосодержащие пятичленные циклические соединения, содержащие два симметричных бета-дикарбонильных заместителя с фторированными радикалами |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB951797A (en) | 1960-12-20 | 1964-03-11 | Monsanto Chemicals | Heterocyclic compounds |
| US3450772A (en) | 1964-12-04 | 1969-06-17 | Mobil Oil Corp | Polyphenyl ethers |
| US5310726A (en) * | 1990-03-19 | 1994-05-10 | Merck & Co., Inc. | Lipopeptide compounds |
| US5066409A (en) | 1990-09-12 | 1991-11-19 | The Dow Chemical Company | Novel aryl ether sulfones |
| JPH07506340A (ja) * | 1991-12-31 | 1995-07-13 | ザ ウースター ファウンデイション フォア バイオメディカル リサーチ | 薬剤耐性マラリアに対する駆虫性オリゴヌクレオチドの活性 |
| US5798340A (en) * | 1993-09-17 | 1998-08-25 | Gilead Sciences, Inc. | Nucleotide analogs |
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-
2009
- 2009-07-28 AU AU2009276744A patent/AU2009276744A1/en not_active Abandoned
- 2009-07-28 KR KR1020117004117A patent/KR20110063435A/ko not_active Withdrawn
- 2009-07-28 BR BRPI0916649-1A patent/BRPI0916649A2/pt not_active IP Right Cessation
- 2009-07-28 MX MX2011000971A patent/MX2011000971A/es not_active Application Discontinuation
- 2009-07-28 WO PCT/US2009/051909 patent/WO2010014573A1/en not_active Ceased
- 2009-07-28 EP EP09803456A patent/EP2321275A4/en not_active Withdrawn
- 2009-07-28 JP JP2011521231A patent/JP2011529502A/ja active Pending
- 2009-07-28 CA CA2732572A patent/CA2732572A1/en not_active Abandoned
- 2009-07-28 RU RU2011107295/04A patent/RU2530899C2/ru not_active IP Right Cessation
- 2009-07-28 US US12/510,593 patent/US8796275B2/en active Active
- 2009-07-28 CN CN2009801378005A patent/CN102164892A/zh active Pending
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2011
- 2011-01-27 IL IL210935A patent/IL210935A0/en unknown
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2014
- 2014-08-05 US US14/452,116 patent/US20150072997A1/en not_active Abandoned
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Also Published As
| Publication number | Publication date |
|---|---|
| CA2732572A1 (en) | 2010-02-04 |
| JP2011529502A (ja) | 2011-12-08 |
| WO2010014573A1 (en) | 2010-02-04 |
| AU2009276744A1 (en) | 2010-02-04 |
| EP2321275A1 (en) | 2011-05-18 |
| MX2011000971A (es) | 2011-06-24 |
| US20100081665A1 (en) | 2010-04-01 |
| BRPI0916649A2 (pt) | 2015-08-04 |
| KR20110063435A (ko) | 2011-06-10 |
| US20150072997A1 (en) | 2015-03-12 |
| US8796275B2 (en) | 2014-08-05 |
| EP2321275A4 (en) | 2012-05-09 |
| CN102164892A (zh) | 2011-08-24 |
| IL210935A0 (en) | 2011-07-31 |
| RU2011107295A (ru) | 2012-09-10 |
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