RU2528884C2 - Лечение опухолей с помощью антитела к vegf - Google Patents

Лечение опухолей с помощью антитела к vegf Download PDF

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Publication number
RU2528884C2
RU2528884C2 RU2009110102/15A RU2009110102A RU2528884C2 RU 2528884 C2 RU2528884 C2 RU 2528884C2 RU 2009110102/15 A RU2009110102/15 A RU 2009110102/15A RU 2009110102 A RU2009110102 A RU 2009110102A RU 2528884 C2 RU2528884 C2 RU 2528884C2
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her2
antibody
cancer
treatment
vegf
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RU2009110102/15A
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English (en)
Russian (ru)
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RU2009110102A (ru
Inventor
ФРИСС Томас
ХАСМАНН Макс
ШОЙЕР Вернер
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Ф.Хоффманн-Ля Рош Аг
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Application filed by Ф.Хоффманн-Ля Рош Аг filed Critical Ф.Хоффманн-Ля Рош Аг
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
RU2009110102/15A 2006-08-21 2007-08-17 Лечение опухолей с помощью антитела к vegf RU2528884C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06017330 2006-08-21
EP06017330.9 2006-08-21
PCT/EP2007/007276 WO2008022746A1 (en) 2006-08-21 2007-08-17 Tumor therapy with an anti-vegf antibody

Publications (2)

Publication Number Publication Date
RU2009110102A RU2009110102A (ru) 2010-09-27
RU2528884C2 true RU2528884C2 (ru) 2014-09-20

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RU2009110102/15A RU2528884C2 (ru) 2006-08-21 2007-08-17 Лечение опухолей с помощью антитела к vegf

Country Status (28)

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US (6) US20080050385A1 (enExample)
EP (2) EP2441472B1 (enExample)
JP (3) JP2010501498A (enExample)
KR (1) KR101136763B1 (enExample)
CN (1) CN101505792B (enExample)
AR (1) AR062419A1 (enExample)
AU (1) AU2007287794B2 (enExample)
BR (1) BRPI0715829A2 (enExample)
CA (1) CA2660681A1 (enExample)
CL (1) CL2007002404A1 (enExample)
CO (1) CO6150193A2 (enExample)
CR (1) CR10590A (enExample)
DK (1) DK2056874T3 (enExample)
ES (2) ES2546066T3 (enExample)
IL (2) IL196810A0 (enExample)
MA (1) MA30654B1 (enExample)
MX (1) MX2009001715A (enExample)
MY (1) MY150756A (enExample)
NO (1) NO20090450L (enExample)
NZ (1) NZ574580A (enExample)
PE (1) PE20080911A1 (enExample)
PL (1) PL2056874T3 (enExample)
RU (1) RU2528884C2 (enExample)
SG (1) SG174090A1 (enExample)
SI (1) SI2056874T1 (enExample)
TW (2) TW201107346A (enExample)
WO (1) WO2008022746A1 (enExample)
ZA (1) ZA200901200B (enExample)

Cited By (1)

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RU2709742C2 (ru) * 2014-10-10 2019-12-19 МЕДИММЬЮН, ЭлЭлСи Гуманизированные антитела к ox40 и способы их применения

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Publication number Priority date Publication date Assignee Title
RU2709742C2 (ru) * 2014-10-10 2019-12-19 МЕДИММЬЮН, ЭлЭлСи Гуманизированные антитела к ox40 и способы их применения

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CO6150193A2 (es) 2010-04-20
NO20090450L (no) 2009-02-27
CN101505792A (zh) 2009-08-12
NZ574580A (en) 2011-12-22
JP2015214582A (ja) 2015-12-03
MY150756A (en) 2014-02-28
CA2660681A1 (en) 2008-02-28
AR062419A1 (es) 2008-11-05
US20080050385A1 (en) 2008-02-28
US20100285010A1 (en) 2010-11-11
TW200825106A (en) 2008-06-16
DK2056874T3 (da) 2012-10-15
CL2007002404A1 (es) 2008-04-18
HK1134441A1 (en) 2010-04-30
BRPI0715829A2 (pt) 2013-07-23
KR101136763B1 (ko) 2012-04-24
US20180251536A1 (en) 2018-09-06
MA30654B1 (fr) 2009-08-03
EP2441472A1 (en) 2012-04-18
EP2441472B1 (en) 2015-06-10
TW201107346A (en) 2011-03-01
US20110223159A1 (en) 2011-09-15
CN101505792B (zh) 2012-10-03
PE20080911A1 (es) 2008-08-15
IL196810A0 (en) 2011-08-01
ES2546066T3 (es) 2015-09-18
AU2007287794A1 (en) 2008-02-28
US20150239969A1 (en) 2015-08-27
SI2056874T1 (sl) 2012-12-31
ES2392630T3 (es) 2012-12-12
EP2056874B1 (en) 2012-09-19
CR10590A (es) 2009-03-20
WO2008022746A1 (en) 2008-02-28
JP2010501498A (ja) 2010-01-21
KR20090032136A (ko) 2009-03-31
EP2056874A1 (en) 2009-05-13
IL238045A0 (en) 2015-05-31
RU2009110102A (ru) 2010-09-27
PL2056874T3 (pl) 2013-02-28
ZA200901200B (en) 2013-08-28
JP2013163687A (ja) 2013-08-22
MX2009001715A (es) 2009-02-25
AU2007287794B2 (en) 2013-03-28
SG174090A1 (en) 2011-09-29
US20130183292A1 (en) 2013-07-18

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