IL196810A0 - Tumor therapy with an anti-vegf antibody - Google Patents
Tumor therapy with an anti-vegf antibodyInfo
- Publication number
- IL196810A0 IL196810A0 IL196810A IL19681009A IL196810A0 IL 196810 A0 IL196810 A0 IL 196810A0 IL 196810 A IL196810 A IL 196810A IL 19681009 A IL19681009 A IL 19681009A IL 196810 A0 IL196810 A0 IL 196810A0
- Authority
- IL
- Israel
- Prior art keywords
- vegf antibody
- tumor therapy
- tumor
- therapy
- vegf
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06017330 | 2006-08-21 | ||
| PCT/EP2007/007276 WO2008022746A1 (en) | 2006-08-21 | 2007-08-17 | Tumor therapy with an anti-vegf antibody |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL196810A0 true IL196810A0 (en) | 2011-08-01 |
Family
ID=37607207
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL196810A IL196810A0 (en) | 2006-08-21 | 2009-01-29 | Tumor therapy with an anti-vegf antibody |
| IL238045A IL238045A0 (en) | 2006-08-21 | 2015-03-30 | Tumor treatment with an antibody against vegf |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL238045A IL238045A0 (en) | 2006-08-21 | 2015-03-30 | Tumor treatment with an antibody against vegf |
Country Status (28)
| Country | Link |
|---|---|
| US (6) | US20080050385A1 (enExample) |
| EP (2) | EP2441472B1 (enExample) |
| JP (3) | JP2010501498A (enExample) |
| KR (1) | KR101136763B1 (enExample) |
| CN (1) | CN101505792B (enExample) |
| AR (1) | AR062419A1 (enExample) |
| AU (1) | AU2007287794B2 (enExample) |
| BR (1) | BRPI0715829A2 (enExample) |
| CA (1) | CA2660681A1 (enExample) |
| CL (1) | CL2007002404A1 (enExample) |
| CO (1) | CO6150193A2 (enExample) |
| CR (1) | CR10590A (enExample) |
| DK (1) | DK2056874T3 (enExample) |
| ES (2) | ES2392630T3 (enExample) |
| IL (2) | IL196810A0 (enExample) |
| MA (1) | MA30654B1 (enExample) |
| MX (1) | MX2009001715A (enExample) |
| MY (1) | MY150756A (enExample) |
| NO (1) | NO20090450L (enExample) |
| NZ (1) | NZ574580A (enExample) |
| PE (1) | PE20080911A1 (enExample) |
| PL (1) | PL2056874T3 (enExample) |
| RU (1) | RU2528884C2 (enExample) |
| SG (1) | SG174090A1 (enExample) |
| SI (1) | SI2056874T1 (enExample) |
| TW (2) | TW200825106A (enExample) |
| WO (1) | WO2008022746A1 (enExample) |
| ZA (1) | ZA200901200B (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001264696B2 (en) | 2000-05-19 | 2007-01-04 | Genentech, Inc. | Gene detection assay for improving the likelihood of an effective response to an ErbB antagonist cancer therapy |
| ZA200701234B (en) * | 2004-07-22 | 2008-12-31 | Genentech Inc | HER2 antibody composition |
| JO3000B1 (ar) * | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| JP2008523073A (ja) * | 2004-12-07 | 2008-07-03 | ジェネンテック・インコーポレーテッド | Her阻害剤を用いた治療のための患者の選択 |
| CA2592177A1 (en) | 2005-01-21 | 2006-07-27 | Genentech, Inc. | Fixed dosing of her antibodies |
| CA2596133C (en) | 2005-02-23 | 2016-11-15 | Genentech, Inc. | Extending time to disease progression or survival in cancer patients |
| PE20070207A1 (es) * | 2005-07-22 | 2007-03-09 | Genentech Inc | Tratamiento combinado de los tumores que expresan el her |
| EP2441472B1 (en) * | 2006-08-21 | 2015-06-10 | F. Hoffmann-La Roche AG | Tumor therapy with an anti-VEGF antibody |
| CA2677108A1 (en) | 2007-03-02 | 2008-09-12 | Genentech, Inc. | Predicting response to a her inhibitor |
| TWI472339B (zh) | 2008-01-30 | 2015-02-11 | Genentech Inc | 包含結合至her2結構域ii之抗體及其酸性變異體的組合物 |
| BRPI0812682A2 (pt) | 2008-06-16 | 2010-06-22 | Genentech Inc | tratamento de cáncer de mama metastático |
| CN107253992B (zh) | 2010-05-27 | 2022-03-11 | 根马布股份公司 | 针对her2的单克隆抗体 |
| CA2800769C (en) | 2010-05-27 | 2021-11-02 | Genmab A/S | Monoclonal antibodies against her2 epitope |
| WO2012010546A1 (en) * | 2010-07-19 | 2012-01-26 | F. Hoffmann-La Roche Ag | Blood plasma biomarkers for bevacizumab combination therapies for treatment of pancreatic cancer |
| PH12013500333A1 (en) * | 2010-08-20 | 2013-04-22 | Novartis Ag | Antibodies for epidermal growth factor receptor 3 (her3) |
| CN103796677B (zh) | 2011-04-20 | 2019-08-16 | 健玛保 | 针对her2和cd3的双特异性抗体 |
| PT4403228T (pt) | 2011-10-14 | 2025-10-07 | Hoffmann La Roche | Utilizações do inibidor da dimerização de her2 pertuzumab e artigo de fabrico que inclui o mesmo |
| CN104067128A (zh) * | 2011-12-05 | 2014-09-24 | 霍夫曼-拉罗奇有限公司 | 贝伐单抗组合疗法用于治疗乳腺癌的血浆生物标志物 |
| US20150147340A1 (en) * | 2012-03-30 | 2015-05-28 | Fibrogen, Inc. | Therapeutic methods for peritoneal carcinomatosis |
| US9815904B2 (en) | 2013-04-16 | 2017-11-14 | Genetech, Inc. | Pertuzumab variants and evaluation thereof |
| KR20160141857A (ko) | 2014-04-25 | 2016-12-09 | 제넨테크, 인크. | 트라스투주맙-mcc-dm1 및 퍼투주맙을 이용하는 초기 유방암의 치료방법 |
| TW201619200A (zh) * | 2014-10-10 | 2016-06-01 | 麥迪紐有限責任公司 | 人類化抗-ox40抗體及其用途 |
| PT3302551T (pt) | 2015-05-30 | 2024-08-21 | H Hoffnabb La Roche Ag | Métodos de tratamento do cancro da mama metastático positivo para her2 não tratado previamente |
| WO2017087280A1 (en) | 2015-11-16 | 2017-05-26 | Genentech, Inc. | Methods of treating her2-positive cancer |
| CN106729743B (zh) | 2015-11-23 | 2021-09-21 | 四川科伦博泰生物医药股份有限公司 | 抗ErbB2抗体-药物偶联物及其组合物、制备方法和应用 |
| TW202140776A (zh) | 2016-04-26 | 2021-11-01 | 美商美國泰福生技股份有限公司 | 細胞培養基 |
| US20180221481A1 (en) | 2016-12-28 | 2018-08-09 | Genentech, Inc. | Treatment of advanced her2 expressing cancer |
| LT3570884T (lt) | 2017-01-17 | 2020-12-10 | Genentech, Inc. | Poodinės her2 antikūnų kompozicijos |
| JP6992081B2 (ja) | 2017-03-02 | 2022-02-03 | ジェネンテック, インコーポレイテッド | Her2陽性乳癌のアジュバント治療 |
| WO2018200505A1 (en) | 2017-04-24 | 2018-11-01 | Genentech, Inc. | Erbb2/her2 mutations in the transmbrane or juxtamembrane domain |
| MX2022015884A (es) | 2020-06-29 | 2023-04-03 | Genentech Inc | Combinacion de dosis fija de pertuzumab mas trastuzumab. |
| JP2023541141A (ja) * | 2020-09-04 | 2023-09-28 | ザ ボード オブ スーパーバイザーズ オブ ルイジアナ ステート ユニバーシティ アンド アグリカルチュラル アンド メカニカル カレッジ | がんを治療するための組み合わせ組成物及び方法 |
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| JP3040121B2 (ja) | 1988-01-12 | 2000-05-08 | ジェネンテク,インコーポレイテッド | 増殖因子レセプターの機能を阻害することにより腫瘍細胞を処置する方法 |
| CA2103059C (en) | 1991-06-14 | 2005-03-22 | Paul J. Carter | Method for making humanized antibodies |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| WO1994010202A1 (en) | 1992-10-28 | 1994-05-11 | Genentech, Inc. | Vascular endothelial cell growth factor antagonists |
| CA2259222A1 (en) | 1996-06-27 | 1997-12-31 | Pfizer Inc. | Derivatives of 2-(2-oxo-ethylidene)-imidazolidin-4-one and their use as farnesyl protein transferase inhibitors |
| CN101412758A (zh) | 1996-10-18 | 2009-04-22 | 基因技术股份有限公司 | 抗ErbB2抗体 |
| EP1695985B1 (en) | 1997-04-07 | 2011-03-09 | Genentech, Inc. | Methods for forming humanised antibodies by random mutagenesis |
| SI1325932T1 (enExample) | 1997-04-07 | 2005-08-31 | Genentech Inc | |
| US20020032315A1 (en) | 1997-08-06 | 2002-03-14 | Manuel Baca | Anti-vegf antibodies |
| US6884879B1 (en) * | 1997-04-07 | 2005-04-26 | Genentech, Inc. | Anti-VEGF antibodies |
| ZA9811162B (en) | 1997-12-12 | 2000-06-07 | Genentech Inc | Treatment with anti-ERBB2 antibodies. |
| JPH11236333A (ja) | 1997-12-30 | 1999-08-31 | Pfizer Prod Inc | 抗ガン剤として有用なイミダゾリン−4−オン誘導体 |
| AU4079999A (en) | 1998-05-15 | 1999-12-06 | Imclone Systems Incorporated | Treatment of human tumors with radiation and inhibitors of growth factor receptor tyrosine kinases |
| BR9913315A (pt) | 1998-08-27 | 2001-05-22 | Pfizer Prod Inc | Derivados de quinolin-2-ona úteis como agentes anticâncer |
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| JP2002530081A (ja) | 1998-11-18 | 2002-09-17 | ジェネンテック・インコーポレーテッド | 親抗体より高度な結合親和性を持つ抗体変異体 |
| EP1006113A1 (en) | 1998-12-02 | 2000-06-07 | Pfizer Products Inc. | Derivatives of 2-(2-oxo-ethylidene)-imidazolidin-4-one and their use to inhibit abnormal cell growth |
| WO2000035956A1 (fr) | 1998-12-16 | 2000-06-22 | Kyowa Hakko Kogyo Co., Ltd. | Anticorps monoclonal anti-vegf humain |
| HK1042096A1 (zh) | 1999-02-11 | 2002-08-02 | 辉瑞产品公司 | 可用作抗癌剂的杂芳基取代的喹啉-2-酮衍生物 |
| US6586447B1 (en) | 1999-04-01 | 2003-07-01 | Pfizer Inc | 3,3-disubstituted-oxindole derivatives useful as anticancer agents |
| AU782325B2 (en) | 1999-05-14 | 2005-07-21 | Genentech Inc. | Treatment with anti-ErbB2 antibodies |
| US6949245B1 (en) * | 1999-06-25 | 2005-09-27 | Genentech, Inc. | Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies |
| BRPI0012198B8 (pt) | 1999-06-25 | 2021-05-25 | Genentech Inc | anticorpos humanizados, composição e imunoconjugado |
| MXPA01013395A (es) | 1999-06-25 | 2003-09-04 | Genentech Inc | Tratamiento de cancer de prostata con anticuerpos anti-erbb2. |
| TR200400342T4 (tr) | 1999-11-30 | 2004-03-22 | Pfizer Products Inc. | Farnezil protein transferazı önlemek için kinolin türevleri. |
| UA75055C2 (uk) | 1999-11-30 | 2006-03-15 | Пфайзер Продактс Інк. | Похідні бензоімідазолу, що використовуються як антипроліферативний засіб, фармацевтична композиція на їх основі |
| HN2000000266A (es) | 2000-01-21 | 2001-05-21 | Pfizer Prod Inc | Compuesto anticanceroso y metodo de separacion de enantiomeros util para sintetizar dicho compuesto. |
| EP1456652A4 (en) * | 2001-11-13 | 2005-11-02 | Dana Farber Cancer Inst Inc | IMMUNOCELL ACTIVATION MODULATING SUBSTANCES AND USE METHOD THEREFOR |
| WO2003077841A2 (en) | 2002-03-12 | 2003-09-25 | The General Hospital Corporation | Use of signal transduction inhibitors and combination therapies for the prevention or treatment of cancer and angiogenesis related diseases |
| JP2005522514A (ja) | 2002-04-10 | 2005-07-28 | ジェネンテック・インコーポレーテッド | 抗her2抗体改変体 |
| US20050186208A1 (en) | 2003-05-30 | 2005-08-25 | Genentech, Inc. | Treatment with anti-VEGF antibodies |
| US20040243207A1 (en) | 2003-05-30 | 2004-12-02 | Olson Donald R. | Medical implant systems |
| US20050106667A1 (en) * | 2003-08-01 | 2005-05-19 | Genentech, Inc | Binding polypeptides with restricted diversity sequences |
| EP1664115A2 (en) | 2003-08-01 | 2006-06-07 | Genentech, Inc. | Antibody cdr polypeptide sequences with restricted diversity |
| AU2004309347B2 (en) | 2003-12-19 | 2010-03-04 | Genentech, Inc. | Monovalent antibody fragments useful as therapeutics |
| US20060204493A1 (en) * | 2004-09-02 | 2006-09-14 | Genentech, Inc. | Heteromultimeric molecules |
| JP4937127B2 (ja) * | 2004-10-04 | 2012-05-23 | ジェネンテック, インコーポレイテッド | 肝細胞成長因子活性化物質のモジュレータ |
| MX349137B (es) * | 2005-06-08 | 2017-07-13 | Dana-Farber Cancer Inst | Metodos y composiciones para el tratamiento de infecciones persistentes y cancer por inhibicion de la ruta de muerte celular programada (pd-1). |
| TW200812615A (en) * | 2006-03-22 | 2008-03-16 | Hoffmann La Roche | Tumor therapy with an antibody for vascular endothelial growth factor and an antibody for human epithelial growth factor receptor type 2 |
| EP2441472B1 (en) * | 2006-08-21 | 2015-06-10 | F. Hoffmann-La Roche AG | Tumor therapy with an anti-VEGF antibody |
| JP2013103182A (ja) * | 2011-11-15 | 2013-05-30 | Toray Ind Inc | スパイラル型流体分離素子およびその製造方法 |
-
2007
- 2007-08-17 EP EP11193793.4A patent/EP2441472B1/en not_active Revoked
- 2007-08-17 WO PCT/EP2007/007276 patent/WO2008022746A1/en not_active Ceased
- 2007-08-17 PL PL07786693T patent/PL2056874T3/pl unknown
- 2007-08-17 ES ES07786693T patent/ES2392630T3/es active Active
- 2007-08-17 CL CL200702404A patent/CL2007002404A1/es unknown
- 2007-08-17 DK DK07786693.7T patent/DK2056874T3/da active
- 2007-08-17 KR KR1020097003557A patent/KR101136763B1/ko not_active Expired - Fee Related
- 2007-08-17 SG SG2011060142A patent/SG174090A1/en unknown
- 2007-08-17 AU AU2007287794A patent/AU2007287794B2/en not_active Ceased
- 2007-08-17 EP EP07786693A patent/EP2056874B1/en not_active Revoked
- 2007-08-17 MY MYPI20090667 patent/MY150756A/en unknown
- 2007-08-17 RU RU2009110102/15A patent/RU2528884C2/ru not_active IP Right Cessation
- 2007-08-17 JP JP2009524943A patent/JP2010501498A/ja active Pending
- 2007-08-17 CN CN2007800308557A patent/CN101505792B/zh not_active Expired - Fee Related
- 2007-08-17 US US11/840,279 patent/US20080050385A1/en not_active Abandoned
- 2007-08-17 CA CA002660681A patent/CA2660681A1/en not_active Abandoned
- 2007-08-17 SI SI200731075T patent/SI2056874T1/sl unknown
- 2007-08-17 ES ES11193793.4T patent/ES2546066T3/es active Active
- 2007-08-17 BR BRPI0715829-7A2A patent/BRPI0715829A2/pt not_active Application Discontinuation
- 2007-08-17 MX MX2009001715A patent/MX2009001715A/es active IP Right Grant
- 2007-08-17 NZ NZ574580A patent/NZ574580A/en not_active IP Right Cessation
- 2007-08-17 AR ARP070103667A patent/AR062419A1/es unknown
- 2007-08-20 PE PE2007001129A patent/PE20080911A1/es not_active Application Discontinuation
- 2007-08-20 TW TW096130765A patent/TW200825106A/zh unknown
- 2007-08-20 TW TW099141756A patent/TW201107346A/zh unknown
-
2009
- 2009-01-29 IL IL196810A patent/IL196810A0/en unknown
- 2009-01-29 CR CR10590A patent/CR10590A/es not_active Application Discontinuation
- 2009-01-29 NO NO20090450A patent/NO20090450L/no not_active Application Discontinuation
- 2009-02-19 ZA ZA2009/01200A patent/ZA200901200B/en unknown
- 2009-02-19 MA MA31650A patent/MA30654B1/fr unknown
- 2009-02-24 CO CO09018558A patent/CO6150193A2/es unknown
-
2010
- 2010-05-20 US US12/784,309 patent/US20100285010A1/en not_active Abandoned
-
2011
- 2011-05-19 US US13/111,784 patent/US20110223159A1/en not_active Abandoned
-
2012
- 2012-08-14 US US13/585,095 patent/US20130183292A1/en not_active Abandoned
-
2013
- 2013-05-15 JP JP2013103182A patent/JP2013163687A/ja not_active Withdrawn
-
2015
- 2015-03-30 IL IL238045A patent/IL238045A0/en unknown
- 2015-05-13 US US14/711,671 patent/US20150239969A1/en not_active Abandoned
- 2015-08-14 JP JP2015160099A patent/JP2015214582A/ja not_active Ceased
-
2017
- 2017-10-23 US US15/791,285 patent/US20180251536A1/en not_active Abandoned
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