RU2527337C9 - Стабилизированная композиция, включающая по крайней мере одно адренергическое соединение - Google Patents
Стабилизированная композиция, включающая по крайней мере одно адренергическое соединение Download PDFInfo
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- RU2527337C9 RU2527337C9 RU2011153410/15A RU2011153410A RU2527337C9 RU 2527337 C9 RU2527337 C9 RU 2527337C9 RU 2011153410/15 A RU2011153410/15 A RU 2011153410/15A RU 2011153410 A RU2011153410 A RU 2011153410A RU 2527337 C9 RU2527337 C9 RU 2527337C9
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- compound
- antioxidant
- adrenaline
- sulfite
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- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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| PCT/EP2010/057771 WO2010139751A2 (en) | 2009-06-04 | 2010-06-03 | Stabilised composition comprising at least one adrenergic compound |
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| RU2011153403/15A RU2527680C2 (ru) | 2009-06-04 | 2010-06-03 | Стабилизированная композиция, содержащая по меньшей мере одно адренергическое соединение |
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| EP (2) | EP2437781B1 (https=) |
| JP (2) | JP2012528830A (https=) |
| KR (2) | KR20120028344A (https=) |
| CN (3) | CN102497882A (https=) |
| AU (2) | AU2010255747B2 (https=) |
| BR (2) | BRPI1011074A2 (https=) |
| CA (2) | CA2764051A1 (https=) |
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| RU (2) | RU2527337C9 (https=) |
| SI (2) | SI2437781T1 (https=) |
| WO (2) | WO2010139752A2 (https=) |
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| US8628805B2 (en) * | 2009-06-04 | 2014-01-14 | Alk Ag | Stabilized composition comprising at least one adrenergic compound |
| CN102525893B (zh) * | 2012-01-04 | 2013-11-20 | 上海禾丰制药有限公司 | 盐酸去氧肾上腺素注射液及其制剂工艺 |
| CN102525894A (zh) * | 2012-01-04 | 2012-07-04 | 上海禾丰制药有限公司 | 盐酸异丙肾上腺素注射液及其制剂工艺 |
| AU2013328393A1 (en) * | 2012-10-08 | 2015-04-09 | Wockhardt Limited | Stable injectable pharmaceutical composition of epinephrine or salts thereof |
| TWI780236B (zh) * | 2013-02-04 | 2022-10-11 | 法商賽諾菲公司 | 胰島素類似物及/或胰島素衍生物之穩定化醫藥調配物 |
| US12239822B2 (en) | 2013-03-15 | 2025-03-04 | Windgap Medical, Inc. | Portable drug mixing and delivery device and associated methods |
| EP3052095A4 (en) | 2013-10-03 | 2017-07-05 | Imprimis Pharmaceuticals Inc. | Epinephrine-based ophthalmic compositions for intraocular administration and methods for fabricating thereof |
| CN103520096B (zh) * | 2013-10-25 | 2015-02-25 | 成都晶博生物科技有限责任公司 | 一种硫酸特布他林注射液的生产工艺 |
| EP3082419A4 (en) * | 2013-12-18 | 2017-09-20 | Windgap Medical, Inc. | Drug mixing and delivery system and method |
| MX2016008979A (es) | 2014-01-09 | 2016-10-04 | Sanofi Sa | Formulaciones farmaceuticas estabilizadas de analogos de insulina y/o derivados de insulina. |
| UY35988A (es) * | 2014-02-27 | 2015-09-30 | Sint Sa | Proceso para la producción de una solución inyectable de noradrenalina de baja concentración |
| EP2990031B1 (en) * | 2014-08-28 | 2019-11-13 | Sun Pharmaceutical Industries Ltd | Parenteral dosage form of norepinephrine |
| CN107205938A (zh) * | 2014-12-18 | 2017-09-26 | 温德加普医疗股份有限公司 | 用于溶解或增溶治疗剂的方法和组合物 |
| US9119876B1 (en) | 2015-03-13 | 2015-09-01 | Par Pharmaceutical, Inc. | Epinephrine formulations |
| US20170189352A1 (en) | 2015-03-13 | 2017-07-06 | Par Pharmaceutical, Inc. | Epinephrine formulations |
| US10039710B2 (en) * | 2015-09-18 | 2018-08-07 | Insys Development Company, Inc. | Epinephrine spray formulations |
| US11517525B2 (en) * | 2015-09-18 | 2022-12-06 | Hikma Pharmaceuticals Usa Inc. | Epinephrine spray formulations |
| EP3503873A4 (en) | 2016-08-25 | 2020-04-15 | Harrow IP, LLC | EPINEPHRINE-BASED OPHTHALMIC COMPOSITIONS FOR INTRAOCULAR ADMINISTRATION AND METHOD FOR THE PRODUCTION THEREOF |
| RU2635759C1 (ru) * | 2016-09-13 | 2017-11-15 | Интеллег Сосьете Анониме | Фармацевтическая композиция для парентерального введения и способ ее получения |
| US10835503B2 (en) * | 2017-01-13 | 2020-11-17 | Teva Pharmaceuticals Usa, Inc. | Pre-filled syringe |
| WO2018140894A1 (en) | 2017-01-30 | 2018-08-02 | Nevakar, Inc | Norepinephrine compositions and methods therefor |
| US20250177328A1 (en) | 2017-01-30 | 2025-06-05 | Nevakar Injectables Inc. | Norepinephrine compositions and methods therefor |
| CN111050760A (zh) * | 2017-04-17 | 2020-04-21 | 希克玛制药美国公司 | 肾上腺素喷雾制剂 |
| WO2019067505A1 (en) | 2017-09-26 | 2019-04-04 | Ys Pharmtech | STABILIZATION OF EPINEPHRINE FORMULATIONS |
| BR112020006950A2 (pt) | 2017-10-10 | 2020-10-06 | Merck Patent Gmbh | composições farmacêuticas injetáveis estabilizadas de l-epinefrina |
| WO2019182745A1 (en) | 2018-03-19 | 2019-09-26 | Bryn Pharma, LLC | Epinephrine spray formulations |
| WO2019183416A1 (en) | 2018-03-23 | 2019-09-26 | Nevakar Inc. | Epinephrine compositions and containers |
| WO2019200076A1 (en) | 2018-04-11 | 2019-10-17 | QuVa Pharma, Inc. | Ready to use liquid reck formulation |
| US10952962B1 (en) | 2018-04-11 | 2021-03-23 | QuVa Pharma, Inc. | Ready to use liquid formulation |
| US10478406B2 (en) | 2019-03-18 | 2019-11-19 | HARC Therapeutics AG | High-pH solid-state epinephrine formulation |
| CN116474219A (zh) * | 2019-06-28 | 2023-07-25 | 四川普锐特药业有限公司 | 保持给药均一度的药物流体分配器及右美托咪定鼻喷器 |
| CN114286669A (zh) * | 2019-08-08 | 2022-04-05 | 太阳医药工业有限公司 | 去甲肾上腺素的输注剂型 |
| USD1004518S1 (en) | 2019-09-09 | 2023-11-14 | Brunswick Corporation | Railing for a marine vessel |
| EP4114336A1 (en) | 2020-03-06 | 2023-01-11 | Baxter International Inc. | Packaged, sealed container system for stable storage of an oxygen sensitive pharmaceutical formulation |
| USD984953S1 (en) | 2021-05-03 | 2023-05-02 | Brunswick Corporation | Safely railing having buoy holder |
| AU2021203856B2 (en) * | 2021-06-10 | 2023-03-09 | Animal Ethics Pty Ltd | Topical anaesthetic composition having improved vasoconstrictor stability |
| US20260027067A1 (en) * | 2022-08-27 | 2026-01-29 | Biophore India Pharmaceuticals Pvt. Ltd. | Trientine liquid dosage forms |
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| US3149035A (en) * | 1961-04-28 | 1964-09-15 | Univ California | Stabilization of epinephrine |
| RU2261092C1 (ru) * | 2003-12-30 | 2005-09-27 | Общество с ограниченной ответственностью "Фарм-Стом" (ООО"Фарм-Стом") | Фармацевтическая композиция, обладающая анестезирующей активностью |
| US20080269347A1 (en) * | 2006-09-28 | 2008-10-30 | Azopharma, Inc. | Epinephrine formulations |
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| GB425678A (en) | 1933-06-15 | 1935-03-15 | Novocol Chemical Mfg Co Inc | Improvements relating to anesthetics for hypodermic injection |
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| CA981182A (en) | 1972-01-07 | 1976-01-06 | Walter A. Borisenok | Stabilization of 1-epinephrine in local anesthetic solutions with a combination of three antioxidants |
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| DD150694A1 (de) | 1980-04-16 | 1981-09-16 | Gisela Raether | Verfahren zur stabilisierung von pharmazeutischen praeparaten mit oxidationsempfindlichen bestandteilen |
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| JP3535537B2 (ja) * | 1993-04-15 | 2004-06-07 | 日本製薬株式会社 | 静脈注射剤 |
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2010
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| US2047144A (en) * | 1934-03-26 | 1936-07-07 | Lilly Co Eli | Stabilized epinephrine-type compound, and process of stabilizing it |
| US3149035A (en) * | 1961-04-28 | 1964-09-15 | Univ California | Stabilization of epinephrine |
| RU2261092C1 (ru) * | 2003-12-30 | 2005-09-27 | Общество с ограниченной ответственностью "Фарм-Стом" (ООО"Фарм-Стом") | Фармацевтическая композиция, обладающая анестезирующей активностью |
| US20080269347A1 (en) * | 2006-09-28 | 2008-10-30 | Azopharma, Inc. | Epinephrine formulations |
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