RU2520823C2 - Аденовирусные векторы и способы и применения, связанные с ними - Google Patents
Аденовирусные векторы и способы и применения, связанные с ними Download PDFInfo
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| RU2788638C2 (ru) * | 2019-03-19 | 2023-01-24 | Вало Терапьютикс Ой | Модифицированные онколитические аденовирусы |
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| CA2812093A1 (en) * | 2010-09-24 | 2012-03-29 | Oncos Therapeutics Oy | Oncolytic adenoviral vectors coding for monoclonal anti - ctla - 4 antibodies |
| BR112013006669A2 (pt) * | 2010-09-24 | 2019-09-24 | Oncos Therapeutics Oy | vetores adenovirais oncolíticos e métodos e usos relacionados aos mesmos |
| FI123955B (en) | 2011-11-25 | 2014-01-15 | Oncos Therapeutics Ltd | Oncolytic adenovirus |
| US10238698B2 (en) | 2012-01-25 | 2019-03-26 | Dnatrix, Inc. | Biomarkers and combination therapies using oncolytic virus and immunomodulation |
| RU2684211C2 (ru) | 2013-02-21 | 2019-04-04 | Тёрнстоун Лимитед Партнершип | Композиция вакцины |
| KR102089121B1 (ko) | 2013-03-14 | 2020-03-13 | 더 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 종양살상형 아데노바이러스 조성물 |
| CA2909432C (en) * | 2013-04-18 | 2025-11-18 | Tilt Biotherapeutics Oy | Enhanced adoptive cell therapy |
| US12421502B2 (en) | 2013-04-18 | 2025-09-23 | Tilt Biotherapeutics Oy | Enhanced adoptive cell therapy |
| US10350275B2 (en) * | 2013-09-21 | 2019-07-16 | Advantagene, Inc. | Methods of cytotoxic gene therapy to treat tumors |
| ES2987442T3 (es) * | 2015-05-04 | 2024-11-14 | Theriva Biologics S L | Adenovirus oncolíticos con mutaciones en epítopos de adenovirus inmunodominantes y su uso en el tratamiento del cáncer |
| FI127460B (en) * | 2016-01-15 | 2018-06-29 | Targovax Oy | Combining adenovirus and chemotherapeutic agents for treating cancer |
| KR20180112024A (ko) | 2016-02-23 | 2018-10-11 | 더 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 바이러스 동역학에 미치는 영향 최소화를 위한 치료용 아데노바이러스의 외인성 유전자 발현 |
| CA3013637A1 (en) | 2016-02-23 | 2017-08-31 | Salk Institute For Biological Studies | High throughput assay for measuring adenovirus replication kinetics |
| EP3426271B1 (en) | 2016-03-10 | 2025-08-27 | CG Oncology, Inc. | Methods of treating solid tumors by combination therapy |
| ES2845690T3 (es) | 2016-09-12 | 2021-07-27 | Targovax Oy | Combinación de adenovirus e inhibidores de punto de control para el tratamiento del cáncer |
| EP3534923A4 (en) * | 2016-11-01 | 2020-05-27 | DNAtrix, Inc. | COMBINATION THERAPY FOR THE TREATMENT OF BRAIN CARCINOMAS |
| AU2017375633C1 (en) | 2016-12-12 | 2023-04-27 | Salk Institute For Biological Studies | Tumor-targeting synthetic adenoviruses and uses thereof |
| CN108261426B (zh) * | 2017-01-04 | 2019-04-05 | 杭州康万达医药科技有限公司 | 药物组合物及其在治疗肿瘤和/或癌症的药物中的应用 |
| KR20190104051A (ko) * | 2017-01-06 | 2019-09-05 | 스타빌리테크 바이오파마 리미티드 | 바이러스 |
| AU2018251987B2 (en) | 2017-04-14 | 2024-11-28 | Cg Oncology, Inc. | Methods of treating bladder cancer |
| NZ758626A (en) | 2017-04-21 | 2023-09-29 | Baylor College Medicine | Oncolytic virotherapy and immunotherapy |
| AU2018273963B2 (en) | 2017-05-25 | 2023-07-20 | University Of Central Florida Research Foundation, Inc. | Novel oncolytic viruses for sensitizing tumor cells to killing by natural killer cells |
| US11896635B2 (en) | 2017-11-08 | 2024-02-13 | Kagoshima University | Oncolytic virus (oncolytic immunotherapy) capable of effectively treating even metastatic cancer while ensuring safety, with expression control system providing optimal expression level of mounted immunogenic gene |
| GB201804473D0 (en) * | 2018-03-21 | 2018-05-02 | Valo Therapeutics Oy | Modified oncolytic adenoviruses |
| AU2019251356B2 (en) | 2018-04-09 | 2025-06-12 | Salk Institute For Biological Studies | Oncolytic adenovirus compositions with enhanced replication properties |
| EP3725323A1 (en) | 2019-04-17 | 2020-10-21 | Targovax Asa | Oncolytic adenoviral vector expressing a member of the b7 family of costimulatory ligands and ada |
| EP3725888A1 (en) * | 2019-04-17 | 2020-10-21 | Targovax Asa | Oncolytic adenoviral vector expressing peptidylarginine deiminase and tissue inhibitor of metalloproteinase |
| EP3725322A1 (en) | 2019-04-17 | 2020-10-21 | Targovax Asa | Oncolytic adenoviral vector expressing granzyme and perforin |
| US20240293487A1 (en) * | 2020-03-25 | 2024-09-05 | Jin-Woo Choi | Immunoevasive anti-tumor adenovirus |
| CN111909962A (zh) * | 2020-07-23 | 2020-11-10 | 药鼎(北京)国际细胞医学技术有限公司 | 一种治疗肝癌的病毒构建体及其用途和构建方法 |
| CN118853767A (zh) * | 2024-08-22 | 2024-10-29 | 华中科技大学同济医学院附属同济医院 | 一种新型溶瘤腺病毒载体及其构建方法和应用 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2788638C9 (ru) * | 2018-03-21 | 2023-12-25 | Вало Терапьютикс Ой | Модифицированные онколитические аденовирусы |
| RU2788638C2 (ru) * | 2019-03-19 | 2023-01-24 | Вало Терапьютикс Ой | Модифицированные онколитические аденовирусы |
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| ES2612889T3 (es) | 2017-05-19 |
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| SG173432A1 (en) | 2011-09-29 |
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| AU2009332883B2 (en) | 2015-05-21 |
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| BRPI0924123B8 (pt) | 2021-05-25 |
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| WO2010072900A1 (en) | 2010-07-01 |
| KR101761094B1 (ko) | 2017-08-04 |
| AU2009332883A1 (en) | 2011-07-07 |
| CN102264760A (zh) | 2011-11-30 |
| PT2379586T (pt) | 2017-02-09 |
| CY1120039T1 (el) | 2018-12-12 |
| LT2379586T (lt) | 2017-03-10 |
| JP2012513209A (ja) | 2012-06-14 |
| HRP20170165T1 (hr) | 2017-04-07 |
| HUE031689T2 (en) | 2017-07-28 |
| PL2379586T3 (pl) | 2017-08-31 |
| DK2379586T3 (en) | 2017-02-06 |
| EP2379586A1 (en) | 2011-10-26 |
| KR20110096579A (ko) | 2011-08-30 |
| SI2379586T1 (sl) | 2017-02-28 |
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