RU2450828C2 - Композиции в виде сухого порошка и системы для вакцинации домашней птицы - Google Patents

Композиции в виде сухого порошка и системы для вакцинации домашней птицы Download PDF

Info

Publication number
RU2450828C2
RU2450828C2 RU2008140745/15A RU2008140745A RU2450828C2 RU 2450828 C2 RU2450828 C2 RU 2450828C2 RU 2008140745/15 A RU2008140745/15 A RU 2008140745/15A RU 2008140745 A RU2008140745 A RU 2008140745A RU 2450828 C2 RU2450828 C2 RU 2450828C2
Authority
RU
Russia
Prior art keywords
virus
dry powder
poultry
vaccination
powder composition
Prior art date
Application number
RU2008140745/15A
Other languages
English (en)
Russian (ru)
Other versions
RU2008140745A (ru
Inventor
Жан Поль РЕМОН (BE)
Жан Поль РЕМОН
Крис ВЕРВАТ (BE)
Крис ВЕРВАТ
Эви КОРБАНИ (BE)
Эви Корбани
Йоханнес Хубертус Хенрикус ВАН ЭК (NL)
Йоханнес Хубертус Хенрикус ВАН ЭК
Вильхельмус Йоханнес Матернус ЛАНДМАН (NL)
Вильхельмус Йоханнес Матернус ЛАНДМАН
Original Assignee
Университейт Гент
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Университейт Гент filed Critical Университейт Гент
Publication of RU2008140745A publication Critical patent/RU2008140745A/ru
Application granted granted Critical
Publication of RU2450828C2 publication Critical patent/RU2450828C2/ru

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/544Mucosal route to the airways
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18111Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
RU2008140745/15A 2006-03-15 2007-03-15 Композиции в виде сухого порошка и системы для вакцинации домашней птицы RU2450828C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06005245A EP1834651A1 (en) 2006-03-15 2006-03-15 Compositions and methods for veterinary vaccination
EP06005245.3 2006-03-15

Publications (2)

Publication Number Publication Date
RU2008140745A RU2008140745A (ru) 2010-04-20
RU2450828C2 true RU2450828C2 (ru) 2012-05-20

Family

ID=37564170

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2008140745/15A RU2450828C2 (ru) 2006-03-15 2007-03-15 Композиции в виде сухого порошка и системы для вакцинации домашней птицы

Country Status (14)

Country Link
US (2) US20090041852A1 (enExample)
EP (2) EP1834651A1 (enExample)
JP (1) JP2009529558A (enExample)
CN (1) CN101415437A (enExample)
BR (1) BRPI0708983A2 (enExample)
DK (1) DK1993605T3 (enExample)
ES (1) ES2389864T3 (enExample)
MX (1) MX2008011701A (enExample)
PL (1) PL1993605T3 (enExample)
PT (1) PT1993605E (enExample)
RU (1) RU2450828C2 (enExample)
SI (1) SI1993605T1 (enExample)
UA (1) UA96754C2 (enExample)
WO (1) WO2007104562A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2826263C2 (ru) * 2013-09-27 2024-09-09 Интервет Интернэшнл Б.В. Сухие композиции вакцин, стабильные при комнатной температуре

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1834651A1 (en) * 2006-03-15 2007-09-19 Universiteit Gent Compositions and methods for veterinary vaccination
PL2105129T3 (pl) 2008-03-24 2018-04-30 Intervet International B.V. Szczepionki w kapsułkach do szczepienia doustnego i wzmocnienia dla ryb i innych zwierząt
US8778384B2 (en) 2008-03-24 2014-07-15 Advanced Bionutrition Corporation Compositions and methods for encapsulating vaccines for the oral vaccination and boostering of fish and other animals
EP2352516A2 (en) * 2008-09-26 2011-08-10 Auburn University Immunization of avians by mucosal administration of non-replicating vectored vaccines
US9610343B2 (en) 2009-05-20 2017-04-04 Aeras Global Tb Vaccine Foundation Stable, spray dryed, immunogenic, viral compositions
JP5550277B2 (ja) * 2009-07-23 2014-07-16 長谷川香料株式会社 保存安定性に優れた粉末組成物
UA110328C2 (en) * 2009-08-21 2015-12-25 Merial Ltd Recombinant vaccine based on avian paramixoviruses and method for its preparation and administration
US20130071421A1 (en) * 2009-10-02 2013-03-21 W. Ian Lipkin Turkey viral hepatitis virus and uses thereof
CN102772799A (zh) * 2012-05-31 2012-11-14 郑州后羿制药有限公司 一种鸭病毒性肝炎、鸭瘟二联卵黄抗体冻干粉及其制备方法
CN103083659B (zh) * 2013-01-18 2015-05-13 北京华夏兴洋生物科技有限公司 新型无油佐剂制备方法及用途
WO2018050873A1 (en) 2016-09-16 2018-03-22 Leukocare Ag A novel method for producing low viscous and highly concentrated biopharmaceutical drug products in liquid formulation
WO2018050872A1 (en) * 2016-09-16 2018-03-22 Leukocare Ag A novel method for obtaining efficient viral vector-based compositions for vaccination or gene therapy
CN107019707A (zh) * 2017-03-14 2017-08-08 杨凌绿方生物工程有限公司 一种鸡胚成纤维细胞产品冻干工艺方法
TR201718859A2 (tr) * 2017-11-27 2017-12-21 Bilge Kaan Tekelioglu Siğirlarin gangrenli̇ nezlesi̇ i̇çi̇n aşi ve aşinin üreti̇m yöntemi̇
CN109260467B (zh) * 2018-08-17 2021-08-20 山东信得科技股份有限公司 一种预防雏鹅痛风症状的疫苗
EP3698773A1 (en) 2019-02-21 2020-08-26 Università degli Studi di Parma Composition and manufacturing of powders containing nanoadjuvants for mucosal vaccination
CN113599513A (zh) * 2020-10-23 2021-11-05 青岛大学 一种适用于咽喉部接种的新型冠状病毒疫苗的制备方法及接种方法
AU2022398370A1 (en) * 2021-11-25 2024-05-30 Orexo Ab Pharmaceutical composition comprising biopharmaceutical drug compounds

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2035909C1 (ru) * 1993-06-02 1995-05-27 Виноходов Владимир Олегович Препарат для профилактики и лечения заболеваний птиц
RU97112459A (ru) * 1994-12-22 1999-05-27 Астра Актиеболаг Аэрозольные формы лекарственных композиций
US6651655B1 (en) * 2000-01-18 2003-11-25 Quadrant Technologies Limited Inhaled vaccines

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58105310U (ja) * 1982-01-11 1983-07-18 貝原 睦衛 ひよこ用ワクチン点眼装置
JPS5924019U (ja) * 1982-08-05 1984-02-15 イカリ消毒株式会社 動物用ワクチン投与装置
GB9607035D0 (en) * 1996-04-03 1996-06-05 Andaris Ltd Spray-dried microparticles as therapeutic vehicles
SE9801288D0 (sv) * 1998-04-14 1998-04-14 Astra Ab Vaccine delivery system and metod of production
AU2003221888B2 (en) * 2002-04-11 2008-11-06 Medimmune, Llc Preservation of bioactive materials by spray drying
AU2002951692A0 (en) * 2002-09-23 2002-10-17 Vital Biotech (Hong Kong) Limited Improvements in or relating to vaccines
KR20100107083A (ko) * 2002-12-17 2010-10-04 메디뮨 엘엘씨 생물활성 물질의 고압 분무 건조
US20050207983A1 (en) * 2004-03-05 2005-09-22 Pulmatrix, Inc. Formulations decreasing particle exhalation
JP2008505192A (ja) * 2004-06-14 2008-02-21 メッドイミューン バクシーンズ,インコーポレイティド 生物活性材料の高圧噴霧乾燥
EP1834651A1 (en) * 2006-03-15 2007-09-19 Universiteit Gent Compositions and methods for veterinary vaccination

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2035909C1 (ru) * 1993-06-02 1995-05-27 Виноходов Владимир Олегович Препарат для профилактики и лечения заболеваний птиц
RU97112459A (ru) * 1994-12-22 1999-05-27 Астра Актиеболаг Аэрозольные формы лекарственных композиций
US6651655B1 (en) * 2000-01-18 2003-11-25 Quadrant Technologies Limited Inhaled vaccines

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2826263C2 (ru) * 2013-09-27 2024-09-09 Интервет Интернэшнл Б.В. Сухие композиции вакцин, стабильные при комнатной температуре

Also Published As

Publication number Publication date
EP1993605A1 (en) 2008-11-26
RU2008140745A (ru) 2010-04-20
PL1993605T3 (pl) 2012-12-31
WO2007104562A1 (en) 2007-09-20
US20110150940A1 (en) 2011-06-23
BRPI0708983A2 (pt) 2011-06-21
CN101415437A (zh) 2009-04-22
PT1993605E (pt) 2012-09-17
MX2008011701A (es) 2008-11-27
DK1993605T3 (da) 2012-09-10
ES2389864T3 (es) 2012-11-02
UA96754C2 (ru) 2011-12-12
EP1993605B1 (en) 2012-06-27
SI1993605T1 (sl) 2012-11-30
JP2009529558A (ja) 2009-08-20
US20090041852A1 (en) 2009-02-12
EP1834651A1 (en) 2007-09-19

Similar Documents

Publication Publication Date Title
RU2450828C2 (ru) Композиции в виде сухого порошка и системы для вакцинации домашней птицы
RU2339400C2 (ru) Стабилизированная вакцинная композиция для стимулирования иммунного ответа и способ ее получения
Audouy et al. Development of a dried influenza whole inactivated virus vaccine for pulmonary immunization
US10159644B2 (en) Inhalable vaccine compositions and methods
Calderon-Nieva et al. Veterinary vaccine nanotechnology: pulmonary and nasal delivery in livestock animals
KR20040073438A (ko) 입자 형태의 약제학적 조성물
JP2009106790A (ja) 乾燥粉末を調整するための噴霧乾燥法
Tomar et al. Passive inhalation of dry powder influenza vaccine formulations completely protects chickens against H5N1 lethal viral challenge
EA031229B1 (ru) Способ витрификации биологического материала
Huyge et al. Suitability of differently formulated dry powder Newcastle disease vaccines for mass vaccination of poultry
Corbanie et al. Vaccination of broiler chickens with dispersed dry powder vaccines as an alternative for liquid spray and aerosol vaccination
Garmise et al. Dry powder nasal vaccines as an alternative to needle-based delivery
CN109045291B (zh) 一种猪支原体肺炎气溶胶活疫苗及其制备方法
JP5105524B2 (ja) 多価鳥インフルエンザウイルス
JPWO2019021957A1 (ja) 点鼻用乾燥粉末医薬組成物
Huyge Dry powder vaccines for mass vaccination of poultry: new formulations, comparison with liquid vaccines and feasibility to decrease adverse vaccinal reactions
Searles et al. Spray drying of biopharmaceuticals and vaccines
Shawky et al. Comparative Protective Efficiency of Different Stabilizers for Live Newcastle Disease Virus Vaccine Production
Corbanie Development of a dry powder vaccine for mass vaccination of poultry
Khodayari et al. Evaluation of different routes of vaccination by clone vaccine on humoral antibody response.
Corbanie et al. VACCINATION OF CHICKENS WITH DRY POWDER VACCINES AS AN ALTERNATIVE TO LIQUID SPRAY AND AEROSOL VACCINATION
AU2003264166A1 (en) Improvements in or relating to vaccines
Bajrovic Development and Characterization of Thermostable Thin Films as a Novel Vaccine Dosage Form
WO2025029323A1 (en) Compositions, methods, and uses for polynucleotide formulations for drying and prolonged storage
ES2744126T3 (es) Vacuna contra la gripe felina y método de uso

Legal Events

Date Code Title Description
MM4A The patent is invalid due to non-payment of fees

Effective date: 20140316