RU2450802C2 - Офтальмологические устройства и способы их изготовления и применения - Google Patents

Офтальмологические устройства и способы их изготовления и применения Download PDF

Info

Publication number
RU2450802C2
RU2450802C2 RU2009121444/15A RU2009121444A RU2450802C2 RU 2450802 C2 RU2450802 C2 RU 2450802C2 RU 2009121444/15 A RU2009121444/15 A RU 2009121444/15A RU 2009121444 A RU2009121444 A RU 2009121444A RU 2450802 C2 RU2450802 C2 RU 2450802C2
Authority
RU
Russia
Prior art keywords
biologically active
active agent
matrix
polymer matrix
prepolymer
Prior art date
Application number
RU2009121444/15A
Other languages
English (en)
Russian (ru)
Other versions
RU2009121444A (ru
Inventor
Джон Даллас ПРУИТ (US)
Джон Даллас ПРУИТ
Линн Кук УИНТЕРТОН (US)
Линн Кук Уинтертон
Джон Мартин ЛАЛЛИ (US)
Джон Мартин ЛАЛЛИ
Original Assignee
Новартис Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Новартис Аг filed Critical Новартис Аг
Publication of RU2009121444A publication Critical patent/RU2009121444A/ru
Application granted granted Critical
Publication of RU2450802C2 publication Critical patent/RU2450802C2/ru

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • A61K9/0051Ocular inserts or implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/453Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • GPHYSICS
    • G02OPTICS
    • G02CSPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00Optical parts
    • G02C7/02Lenses; Lens systems ; Methods of designing lenses
    • G02C7/04Contact lenses for the eyes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Preparation (AREA)
  • Eyeglasses (AREA)
  • Materials For Medical Uses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU2009121444/15A 2006-11-06 2007-11-05 Офтальмологические устройства и способы их изготовления и применения RU2450802C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86442806P 2006-11-06 2006-11-06
US60/864,428 2006-11-06

Publications (2)

Publication Number Publication Date
RU2009121444A RU2009121444A (ru) 2010-12-20
RU2450802C2 true RU2450802C2 (ru) 2012-05-20

Family

ID=39284102

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2009121444/15A RU2450802C2 (ru) 2006-11-06 2007-11-05 Офтальмологические устройства и способы их изготовления и применения

Country Status (15)

Country Link
US (1) US20080124376A1 (enExample)
EP (1) EP2094235A2 (enExample)
JP (1) JP5586956B2 (enExample)
KR (1) KR101454041B1 (enExample)
CN (1) CN101534793A (enExample)
AR (1) AR063561A1 (enExample)
AU (1) AU2007332930B2 (enExample)
BR (1) BRPI0718543A2 (enExample)
CA (2) CA2668576C (enExample)
MX (1) MX2009004365A (enExample)
NO (1) NO20092101L (enExample)
RU (1) RU2450802C2 (enExample)
TW (1) TWI476022B (enExample)
WO (1) WO2008073193A2 (enExample)
ZA (1) ZA200901842B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2578835C2 (ru) * 2013-01-09 2016-03-27 Джонсон Энд Джонсон Вижн Кэа, Инк. Многоэлементное вставное устройство с клеевым герметизирующим уплотнителем для офтальмологических устройств
RU2686339C2 (ru) * 2013-09-27 2019-04-25 Новартис Аг Композиции и способы дезинфекции и очищения контактных линз

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090088846A1 (en) 2007-04-17 2009-04-02 David Myung Hydrogel arthroplasty device
US9877973B2 (en) 2008-05-12 2018-01-30 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
US10064819B2 (en) 2008-05-12 2018-09-04 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
JP5591226B2 (ja) 2008-05-12 2014-09-17 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション 眼内薬物送達装置および関連する方法
US9095404B2 (en) 2008-05-12 2015-08-04 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
US20120209396A1 (en) 2008-07-07 2012-08-16 David Myung Orthopedic implants having gradient polymer alloys
CA2731159A1 (en) 2008-07-21 2010-01-28 Novartis Ag Silicone hydrogel contact lenses with convertible comfort agents
TWI531362B (zh) 2008-07-21 2016-05-01 艾爾康股份有限公司 具有治療劑遞送能力之眼科裝置
EP2323670A4 (en) 2008-08-05 2013-12-25 Biomimedica Inc POLYURETHANE-GEPPROPFTE HYDROGELE
TWI506333B (zh) 2008-12-05 2015-11-01 Novartis Ag 用以傳遞疏水性舒適劑之眼用裝置及其製造方法
JP5890182B2 (ja) 2009-02-12 2016-03-22 インセプト エルエルシー ヒドロゲルプラグによる薬物送達
JP5247597B2 (ja) 2009-06-03 2013-07-24 株式会社シード 湿潤性ハイドロゲルコンタクトレンズ及びその製造方法
US9522980B2 (en) 2010-05-06 2016-12-20 Johnson & Johnson Vision Care, Inc. Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same
ES2980213T3 (es) 2010-07-30 2024-09-30 Alcon Inc Lentes de hidrogel de silicona con superficies ricas en agua
US20130217829A1 (en) 2010-08-27 2013-08-22 David Myung "hydrophobic and hydrophilic interpenetrating polymer networks derived from hydrophobic polymers and methods of preparing the same"
US9170349B2 (en) * 2011-05-04 2015-10-27 Johnson & Johnson Vision Care, Inc. Medical devices having homogeneous charge density and methods for making same
US20130203813A1 (en) 2011-05-04 2013-08-08 Johnson & Johnson Vision Care, Inc. Medical devices having homogeneous charge density and methods for making same
CN103597378B (zh) 2011-06-09 2017-02-15 诺瓦提斯公司 具有纳米纹理化表面的硅氧烷水凝胶透镜
ES2725784T3 (es) * 2011-07-20 2019-09-27 Univ Brigham Young Compuestos de ceragenina hidrófobos y dispositivos que incorporan al mismo
US10226417B2 (en) 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications
WO2013052105A2 (en) 2011-10-03 2013-04-11 Biomimedica, Inc. Polymeric adhesive for anchoring compliant materials to another surface
AU2012340699A1 (en) 2011-11-21 2014-06-19 Biomimedica, Inc. Systems, devices, and methods for anchoring orthopaedic implants to bone
EP2846634A2 (en) 2012-05-02 2015-03-18 Brigham Young University Ceragenin particulate materials and methods for making same
US9244196B2 (en) 2012-05-25 2016-01-26 Johnson & Johnson Vision Care, Inc. Polymers and nanogel materials and methods for making and using the same
US10073192B2 (en) 2012-05-25 2018-09-11 Johnson & Johnson Vision Care, Inc. Polymers and nanogel materials and methods for making and using the same
US9297929B2 (en) 2012-05-25 2016-03-29 Johnson & Johnson Vision Care, Inc. Contact lenses comprising water soluble N-(2 hydroxyalkyl) (meth)acrylamide polymers or copolymers
JP6205364B2 (ja) * 2012-09-05 2017-09-27 株式会社メニコン 薬物徐放性眼用レンズ及びその製造方法
HUE031702T2 (en) 2012-12-17 2017-07-28 Novartis Ag A method for producing improved UV absorbing ophthalmic lenses
US9161598B2 (en) 2012-12-21 2015-10-20 Coopervision International Holding Company, Lp Ophthalmic devices for delivery of beneficial agents
US9248928B2 (en) 2012-12-21 2016-02-02 Coopervision International Holding Company, Lp Methods of manufacturing contact lenses for delivery of beneficial agents
US9498035B2 (en) 2012-12-21 2016-11-22 Coopervision International Holding Company, Lp Silicone hydrogel contact lenses for sustained release of beneficial polymers
EP2941253B1 (en) 2013-01-07 2021-08-11 Brigham Young University Cationic steroid antimicrobial agents for use in treating cancer
LT2950783T (lt) * 2013-02-01 2019-10-25 Allergan Inc Dirbtinės ašaros, kurių sudėtyje yra natrio hialuronato ir karboksimetilceliuliozės
US10568893B2 (en) 2013-03-15 2020-02-25 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
CN110420211A (zh) 2013-03-15 2019-11-08 布莱阿姆青年大学 治疗炎症、自身免疫性疾病和疼痛的方法
US11524015B2 (en) 2013-03-15 2022-12-13 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
US11690855B2 (en) 2013-10-17 2023-07-04 Brigham Young University Methods for treating lung infections and inflammation
MY180543A (en) 2013-12-17 2020-12-01 Novartis Ag A silicone hydrogel lens with a crosslinked hydrophilic coating
US20150203527A1 (en) 2014-01-23 2015-07-23 Brigham Young University Cationic steroidal antimicrobials
CA2844321C (en) 2014-02-27 2021-03-16 Brigham Young University Cationic steroidal antimicrobial compounds
US10220045B2 (en) 2014-03-13 2019-03-05 Brigham Young University Compositions and methods for forming stabilized compositions with reduced CSA agglomeration
US10238665B2 (en) 2014-06-26 2019-03-26 Brigham Young University Methods for treating fungal infections
US10441595B2 (en) 2014-06-26 2019-10-15 Brigham Young University Methods for treating fungal infections
US10227376B2 (en) 2014-08-22 2019-03-12 Brigham Young University Radiolabeled cationic steroid antimicrobials and diagnostic methods
EP3186070B1 (en) 2014-08-26 2019-09-25 Novartis AG Method for applying stable coating on silicone hydrogel contact lenses
US10155788B2 (en) 2014-10-07 2018-12-18 Brigham Young University Cationic steroidal antimicrobial prodrug compositions and uses thereof
WO2016172543A1 (en) 2015-04-22 2016-10-27 Savage Paul B Methods for the synthesis of ceragenins
US11077228B2 (en) 2015-08-10 2021-08-03 Hyalex Orthopaedics, Inc. Interpenetrating polymer networks
HUE051613T2 (hu) 2015-12-15 2021-03-01 Alcon Inc Eljárás szilíciumhidrogél-kontaktlencsékre stabil kivonat felvitelére
US10226550B2 (en) 2016-03-11 2019-03-12 Brigham Young University Cationic steroidal antimicrobial compositions for the treatment of dermal tissue
US10959433B2 (en) 2017-03-21 2021-03-30 Brigham Young University Use of cationic steroidal antimicrobials for sporicidal activity
SG11202003456VA (en) 2017-12-13 2020-07-29 Alcon Inc Method for producing mps-compatible water gradient contact lenses
US10869950B2 (en) 2018-07-17 2020-12-22 Hyalex Orthopaedics, Inc. Ionic polymer compositions
US12186328B2 (en) 2019-05-23 2025-01-07 Brigham Young University Use of CSA compounds to stimulate stem cells and hair growth
MX2022002980A (es) 2019-09-16 2022-04-06 Amgen Inc Metodo para la esterilizacion externa de un dispositivo de suministro de farmacos.
US12393057B2 (en) * 2020-12-15 2025-08-19 Coopervision International Limited Oleic acid-releasing contact lens
US20240118559A1 (en) * 2022-09-27 2024-04-11 Coopervision International Limited Sustained release of oleic acid from contact lenses

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2114579C1 (ru) * 1987-11-09 1998-07-10 Л.Джибсон Дэвид Протез для субэпителиальной имплантации
US5849841A (en) * 1995-02-03 1998-12-15 Ciba Vision Corporation Crosslinked polymers containing ester or amide groups

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL128305C (enExample) * 1963-09-11
FR2402525A1 (fr) * 1977-09-12 1979-04-06 Toray Industries Procede de fabrication de compositions de lentilles de contact molles et nouveaux produits ainsi obtenus
US4444711A (en) * 1981-12-21 1984-04-24 Husky Injection Molding Systems Ltd. Method of operating a two-shot injection-molding machine
US4460534A (en) * 1982-09-07 1984-07-17 International Business Machines Corporation Two-shot injection molding
US4668506A (en) * 1985-08-16 1987-05-26 Bausch & Lomb Incorporated Sustained-release formulation containing and amino acid polymer
DE3875240T2 (de) * 1988-04-09 1993-02-25 Hewlett Packard Gmbh Polyacrylamid-gel.
US4983702A (en) * 1988-09-28 1991-01-08 Ciba-Geigy Corporation Crosslinked siloxane-urethane polymer contact lens
JP3085480B2 (ja) * 1991-10-02 2000-09-11 セイコーエプソン株式会社 ホルモン徐放性コンタクトレンズ
TW272976B (enExample) * 1993-08-06 1996-03-21 Ciba Geigy Ag
US5712356A (en) * 1993-11-26 1998-01-27 Ciba Vision Corporation Cross-linkable copolymers and hydrogels
JPH09507214A (ja) * 1993-12-08 1997-07-22 ビタフォア コーポレイション マイクロスフェアー ドラッグ デリバリー システム
US5894002A (en) * 1993-12-13 1999-04-13 Ciba Vision Corporation Process and apparatus for the manufacture of a contact lens
US5843346A (en) * 1994-06-30 1998-12-01 Polymer Technology Corporation Method of cast molding contact lenses
US5760100B1 (en) * 1994-09-06 2000-11-14 Ciba Vision Corp Extended wear ophthalmic lens
US5665840A (en) * 1994-11-18 1997-09-09 Novartis Corporation Polymeric networks from water-soluble prepolymers
TW349967B (en) * 1995-02-03 1999-01-11 Novartis Ag Process for producing contact lenses and a cross-linkable polyvinylalcohol used therefor
US5583463A (en) * 1995-05-30 1996-12-10 Micron Technology, Inc. Redundant row fuse bank circuit
EP0932635B1 (en) * 1996-10-21 2001-07-11 Novartis AG Crosslinkable polymers
TW425403B (en) * 1997-02-04 2001-03-11 Novartis Ag Branched polyurethane (meth)acrylate prepolymers, opthal-mic mouldings derived therefrom and processes for their manufacture
ES2175698T3 (es) * 1997-02-21 2002-11-16 Novartis Ag Articulos de moldeo oftalmicos.
US5981826A (en) * 1997-05-05 1999-11-09 Georgia Tech Research Corporation Poly(vinyl alcohol) cryogel
US6011082A (en) * 1997-06-02 2000-01-04 Pharmacia & Upjohn Ab Process for the modification of elastomers with surface interpreting polymer networks and elastomers formed therefrom
JP4616473B2 (ja) * 1997-09-16 2011-01-19 ノバルティス アーゲー 架橋結合可能なポリ尿素ポリマー類
TW429327B (en) * 1997-10-21 2001-04-11 Novartis Ag Single mould alignment
US6039913A (en) * 1998-08-27 2000-03-21 Novartis Ag Process for the manufacture of an ophthalmic molding
EP1002807A1 (en) * 1998-11-20 2000-05-24 Novartis AG Functionalized resin derived from polyallylamine
US6395756B2 (en) * 1999-12-23 2002-05-28 Novartis Ag Use of ophthalmic agent
WO2001057067A1 (en) * 2000-02-04 2001-08-09 Supratek Pharma Inc. Ligand for vascular endothelial growth factor receptor
AR029901A1 (es) * 2000-03-24 2003-07-23 Novartis Ag Prepolimeros reticulables o polimerizables, y un proceso para la fabricacion de articulos moldeados ''biomedicos'' ''
AR030341A1 (es) * 2000-08-14 2003-08-20 Novartis Ag Articulos biomedicos moldeados
US6511960B2 (en) * 2001-01-05 2003-01-28 Alphamed Pharmaceuticals Corp Cromolyn for eye and ear infections
US20030020870A1 (en) * 2001-06-27 2003-01-30 Zms, Llc Biomedical molding materials from semi-solid precursors
US20060100408A1 (en) * 2002-03-11 2006-05-11 Powell P M Method for forming contact lenses comprising therapeutic agents
DE60317797T2 (de) * 2002-08-14 2008-10-30 Novartis Ag Strahlungshärtbare prepolymere
US20040105880A1 (en) * 2002-11-21 2004-06-03 Turner Josephine Sara Interpenetrating polymer network
JP4937491B2 (ja) * 2003-04-03 2012-05-23 株式会社シード カチオン性高分子ゲル及びそれを用いた薬物徐放性高分子ゲル
JP4379778B2 (ja) * 2003-04-03 2009-12-09 株式会社シード 薬物徐放性眼用レンズ
US7927519B2 (en) * 2003-07-30 2011-04-19 Eyesense Ag Reflection hologram sensor in contact lens
US7977430B2 (en) * 2003-11-25 2011-07-12 Novartis Ag Crosslinkable polyurea prepolymers
CA2577513A1 (en) * 2004-11-22 2006-05-26 Novartis Ag Crosslinkable poly(oxyalkylene)-containing polyamide prepolymers
GB0502790D0 (en) * 2005-02-10 2005-03-16 Univ London Pharmacy Solid dispersion of hydrophobic bioactive
US9804295B2 (en) * 2005-05-05 2017-10-31 Novartis Ag Ophthalmic devices for sustained delivery of active compounds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2114579C1 (ru) * 1987-11-09 1998-07-10 Л.Джибсон Дэвид Протез для субэпителиальной имплантации
US5849841A (en) * 1995-02-03 1998-12-15 Ciba Vision Corporation Crosslinked polymers containing ester or amide groups

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PETERSON RC. Et al. Clinical performance of daily disposable soft contact lenses sustained release technology. Cont. Lens Anterior Eye 2006 Jul; 29(3): 127-34, pp.127-134. *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2578835C2 (ru) * 2013-01-09 2016-03-27 Джонсон Энд Джонсон Вижн Кэа, Инк. Многоэлементное вставное устройство с клеевым герметизирующим уплотнителем для офтальмологических устройств
RU2686339C2 (ru) * 2013-09-27 2019-04-25 Новартис Аг Композиции и способы дезинфекции и очищения контактных линз

Also Published As

Publication number Publication date
TW200826985A (en) 2008-07-01
ZA200901842B (en) 2010-05-26
CA2914805C (en) 2017-12-12
RU2009121444A (ru) 2010-12-20
KR20090083901A (ko) 2009-08-04
JP2010508902A (ja) 2010-03-25
WO2008073193A2 (en) 2008-06-19
TWI476022B (zh) 2015-03-11
US20080124376A1 (en) 2008-05-29
CN101534793A (zh) 2009-09-16
MX2009004365A (es) 2009-05-05
CA2914805A1 (en) 2008-06-19
AU2007332930A1 (en) 2008-06-19
JP5586956B2 (ja) 2014-09-10
AU2007332930B2 (en) 2011-03-17
KR101454041B1 (ko) 2014-10-27
CA2668576C (en) 2016-03-22
BRPI0718543A2 (pt) 2013-11-12
WO2008073193A3 (en) 2009-03-26
CA2668576A1 (en) 2008-06-19
AR063561A1 (es) 2009-02-04
EP2094235A2 (en) 2009-09-02
NO20092101L (no) 2009-06-05

Similar Documents

Publication Publication Date Title
JP5586956B2 (ja) 眼のデバイス並びにその製造および使用の方法
ES2993009T3 (en) Wettable silicone hydrogel contact lenses
CN101171531B (zh) 用于持续递送活性化合物的眼科器件
TWI720509B (zh) 矽酮水凝膠接觸鏡片
KR102371794B1 (ko) 그래프팅된 중합체 네트워크를 함유하는 중합체 조성물 및 그의 제조 및 사용 방법
WO2016014403A1 (en) Contact lenses and methods of making contact lenses
TWI820002B (zh) 於中心光學區具增加之韌性的散光矯正軟式隱形眼鏡
TW201504662A (zh) 經施加黏土處理之含聚矽氧隱形眼鏡
HK1131892A (en) Ocular devices and methods of making and using thereof
WO2026042049A1 (en) Double network hydrogel and preparation and application thereof
CN102958508A (zh) 包含趋化因子拮抗剂的眼科装置
HK1182306A (en) Ophthalmic devices containing chemokine antagonists

Legal Events

Date Code Title Description
MM4A The patent is invalid due to non-payment of fees

Effective date: 20201106