RU2434003C2 - Фениламинобензоксазолзамещенные карбоновые кислоты, способ их получения и их применение в качестве лекарственных средств - Google Patents
Фениламинобензоксазолзамещенные карбоновые кислоты, способ их получения и их применение в качестве лекарственных средств Download PDFInfo
- Publication number
- RU2434003C2 RU2434003C2 RU2008148838/04A RU2008148838A RU2434003C2 RU 2434003 C2 RU2434003 C2 RU 2434003C2 RU 2008148838/04 A RU2008148838/04 A RU 2008148838/04A RU 2008148838 A RU2008148838 A RU 2008148838A RU 2434003 C2 RU2434003 C2 RU 2434003C2
- Authority
- RU
- Russia
- Prior art keywords
- alkyl
- formula
- compounds
- compound
- combination
- Prior art date
Links
- 0 O=C(*[C@](Cc(cc1)ccc1Cl)C(N(CC1)CCC1(C[n]1ncnc1)C1CCCCC1)=O)C(C1)*Cc2c1cccc2 Chemical compound O=C(*[C@](Cc(cc1)ccc1Cl)C(N(CC1)CCC1(C[n]1ncnc1)C1CCCCC1)=O)C(C1)*Cc2c1cccc2 0.000 description 2
- ARFBDECCXOFCBN-BMPSLZLPSA-N CC(C)(C)NC(C(CC1)(CCN1C([C@@H](Cc(cc1)ccc1F)NC(C1C(CC2)N(C)C[C@H]2C1)=O)=O)C1CCCCC1)=O Chemical compound CC(C)(C)NC(C(CC1)(CCN1C([C@@H](Cc(cc1)ccc1F)NC(C1C(CC2)N(C)C[C@H]2C1)=O)=O)C1CCCCC1)=O ARFBDECCXOFCBN-BMPSLZLPSA-N 0.000 description 1
- YDGSHFJUSTYFRE-FTJBHMTQSA-N CC(C)(C)NC(C(CC1)(CCN1C([C@@H](Cc(cc1)ccc1F)NC([C@H]1NCCN(C)C1)=O)=O)C1CCCCC1)=O Chemical compound CC(C)(C)NC(C(CC1)(CCN1C([C@@H](Cc(cc1)ccc1F)NC([C@H]1NCCN(C)C1)=O)=O)C1CCCCC1)=O YDGSHFJUSTYFRE-FTJBHMTQSA-N 0.000 description 1
- YBWLTKFZAOSWSM-UHFFFAOYSA-N Cc(cc1)cnc1S(Nc1nc(-c2ccncc2)nc(OC)c1Oc(cccc1)c1OC)(=O)=O Chemical compound Cc(cc1)cnc1S(Nc1nc(-c2ccncc2)nc(OC)c1Oc(cccc1)c1OC)(=O)=O YBWLTKFZAOSWSM-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/423—Oxazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102006021878.7 | 2006-05-11 | ||
| DE102006021878A DE102006021878A1 (de) | 2006-05-11 | 2006-05-11 | Phenylamino-benzoxazol substituierte Carbonsäuren, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2008148838A RU2008148838A (ru) | 2010-06-20 |
| RU2434003C2 true RU2434003C2 (ru) | 2011-11-20 |
Family
ID=38371048
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2008148838/04A RU2434003C2 (ru) | 2006-05-11 | 2007-04-30 | Фениламинобензоксазолзамещенные карбоновые кислоты, способ их получения и их применение в качестве лекарственных средств |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US20090149519A1 (OSRAM) |
| EP (1) | EP2024347B1 (OSRAM) |
| JP (1) | JP2009536629A (OSRAM) |
| KR (1) | KR20090006846A (OSRAM) |
| CN (1) | CN101437805B (OSRAM) |
| AR (1) | AR060990A1 (OSRAM) |
| AU (1) | AU2007250213B2 (OSRAM) |
| BR (1) | BRPI0711448A2 (OSRAM) |
| CA (1) | CA2651660A1 (OSRAM) |
| CO (1) | CO6241107A2 (OSRAM) |
| CY (1) | CY1113177T1 (OSRAM) |
| DE (1) | DE102006021878A1 (OSRAM) |
| DK (1) | DK2024347T3 (OSRAM) |
| ES (1) | ES2391203T3 (OSRAM) |
| HR (1) | HRP20120829T1 (OSRAM) |
| IL (1) | IL195179A0 (OSRAM) |
| MA (1) | MA30402B1 (OSRAM) |
| MX (1) | MX2008014102A (OSRAM) |
| MY (1) | MY148258A (OSRAM) |
| NO (1) | NO20085068L (OSRAM) |
| NZ (1) | NZ572692A (OSRAM) |
| PL (1) | PL2024347T3 (OSRAM) |
| PT (1) | PT2024347E (OSRAM) |
| RS (1) | RS52450B (OSRAM) |
| RU (1) | RU2434003C2 (OSRAM) |
| SI (1) | SI2024347T1 (OSRAM) |
| TW (1) | TW200812987A (OSRAM) |
| UY (1) | UY30338A1 (OSRAM) |
| WO (1) | WO2007131622A1 (OSRAM) |
| ZA (1) | ZA200808490B (OSRAM) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7465804B2 (en) | 2005-05-20 | 2008-12-16 | Amgen Inc. | Compounds, pharmaceutical compositions and methods for their use in treating metabolic disorders |
| AU2006291234A1 (en) | 2005-09-14 | 2007-03-22 | Amgen Inc. | Conformationally constrained 3- (4-hydroxy-phenyl) - substituted-propanoic acids useful for treating metabolic disorders |
| WO2008030520A1 (en) | 2006-09-07 | 2008-03-13 | Amgen Inc. | Heterocyclic gpr40 modulators |
| US7687526B2 (en) | 2006-09-07 | 2010-03-30 | Amgen Inc. | Benzo-fused compounds for use in treating metabolic disorders |
| WO2008130514A1 (en) | 2007-04-16 | 2008-10-30 | Amgen Inc. | Substituted biphenyl phenoxy-, thiophenyl- and aminophenylpropanoic acid gpr40 modulators |
| EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| BRPI0818253A2 (pt) | 2007-10-10 | 2015-04-07 | Amgen Inc | Moduladores de gpr40 bifenil substituídos |
| WO2009145829A1 (en) | 2008-04-01 | 2009-12-03 | University Of Massachusetts | Type iii secretion inhibitors, analogs and uses thereof |
| EP2260017A1 (en) | 2008-03-06 | 2010-12-15 | Amgen, Inc | Conformationally constrained carboxylic acid derivatives useful for treating metabolic disorders |
| ES2450567T3 (es) | 2008-10-15 | 2014-03-25 | Amgen, Inc | Moduladores de GPR40 espirocíclicos |
| WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| EP3159331A1 (en) | 2010-05-05 | 2017-04-26 | Infinity Pharmaceuticals, Inc. | Tetrazolones as inhibitors of fatty acid synthase |
| US8450350B2 (en) | 2010-05-05 | 2013-05-28 | Infinity Pharmaceuticals, Inc. | Triazoles as inhibitors of fatty acid synthase |
| EP2582709B1 (de) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| JP2013538215A (ja) | 2010-08-31 | 2013-10-10 | エスエヌユー アールアンドディービー ファウンデーション | ＰＰＡＲδアゴニストの胎児再プログラミング用途 |
| WO2012120056A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| WO2012120053A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2683699B1 (de) | 2011-03-08 | 2015-06-24 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2683705B1 (de) | 2011-03-08 | 2015-04-22 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| US8901114B2 (en) | 2011-03-08 | 2014-12-02 | Sanofi | Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof |
| WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| TW201317229A (zh) * | 2011-09-14 | 2013-05-01 | Daiichi Sankyo Co Ltd | 稠合雜環衍生物 |
| EP2760862B1 (en) | 2011-09-27 | 2015-10-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| IN2015DN03795A (OSRAM) | 2012-10-24 | 2015-10-02 | Inserm Inst Nat De La Santé Et De La Rech Médicale | |
| EP3076959B1 (en) | 2013-12-04 | 2018-07-04 | Merck Sharp & Dohme Corp. | Antidiabetic bicyclic compounds |
| US10059667B2 (en) | 2014-02-06 | 2018-08-28 | Merck Sharp & Dohme Corp. | Antidiabetic compounds |
| WO2016151018A1 (en) | 2015-03-24 | 2016-09-29 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Method and pharmaceutical composition for use in the treatment of diabetes |
| JP7062792B2 (ja) | 2018-02-13 | 2022-05-06 | ギリアード サイエンシーズ， インコーポレイテッド | Ｐｄ－１／ｐｄ－ｌ１阻害剤 |
| EP3781556B1 (en) | 2018-04-19 | 2025-06-18 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
| CN118221646A (zh) | 2018-07-13 | 2024-06-21 | 吉利德科学公司 | Pd-1/pd-l1抑制剂 |
| KR102635333B1 (ko) | 2018-10-24 | 2024-02-15 | 길리애드 사이언시즈, 인코포레이티드 | Pd-1/pd-l1 억제제 |
| JP7680955B2 (ja) | 2019-01-11 | 2025-05-21 | ネイジス ファーマシューティカルズ インコーポレイテッド | ロイコトリエン合成阻害剤 |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2450042A1 (de) * | 1973-10-23 | 1975-04-24 | Lilly Industries Ltd | Neue benzoxazolderivate und verfahren zu ihrer herstellung |
| WO1991019702A1 (en) * | 1990-06-14 | 1991-12-26 | Pfizer Inc. | 3-aryl-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
| WO1994008962A1 (en) * | 1992-10-14 | 1994-04-28 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| RU2080321C1 (ru) * | 1991-09-24 | 1997-05-27 | Берингер Ингельгейм Фармасьютикалз Инк. | Азотсодержащие гетероциклические соединения в виде рацемата или отдельных энантиомеров, являющиеся ингибиторами биосинтеза лейкотриена |
| WO1998040381A1 (en) * | 1997-03-14 | 1998-09-17 | Vertex Pharmaceuticals Incorporated | Inhibitors of impdh enzyme |
| WO2000049005A1 (en) * | 1999-02-16 | 2000-08-24 | Aventis Pharma Limited | Bicyclic compounds and their use as integrin receptor ligands |
| WO2005070920A1 (en) * | 2004-01-21 | 2005-08-04 | Bristol-Myers Squibb Company | Amino-benzazoles as p2y1 receptor inhibitors |
| WO2005070906A1 (en) * | 2004-01-21 | 2005-08-04 | Novartis Ag | Organic compounds |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4025637A (en) * | 1973-10-23 | 1977-05-24 | Lilly Industries, Ltd. | 2,5 OR 2,6 Disubstituted benzoxazoles |
| WO2000005223A2 (en) * | 1998-07-23 | 2000-02-03 | Astrazeneca Ab | Heterocyclic derivatives and their use as integrin inhibitors |
| GB0001346D0 (en) * | 2000-01-21 | 2000-03-08 | Astrazeneca Uk Ltd | Chemical compounds |
| MXPA03003829A (es) * | 2000-11-04 | 2003-07-28 | Aventis Pharma Ltd | Acidos alcanoicos substituidos. |
| US7157487B2 (en) * | 2000-12-28 | 2007-01-02 | Daiichi Pharmaceutical Co., Ltd. | Vla-4 inhibitors |
| JP4805552B2 (ja) * | 2003-05-30 | 2011-11-02 | 武田薬品工業株式会社 | 縮合環化合物 |
| JP2006056830A (ja) * | 2004-08-20 | 2006-03-02 | Dai Ichi Seiyaku Co Ltd | ２−アリールアミノベンゾオキサゾール誘導体 |
-
2006
- 2006-05-11 DE DE102006021878A patent/DE102006021878A1/de not_active Withdrawn
-
2007
- 2007-04-30 MY MYPI20084472A patent/MY148258A/en unknown
- 2007-04-30 MX MX2008014102A patent/MX2008014102A/es active IP Right Grant
- 2007-04-30 JP JP2009508193A patent/JP2009536629A/ja active Pending
- 2007-04-30 HR HRP20120829TT patent/HRP20120829T1/hr unknown
- 2007-04-30 RS RS20120395A patent/RS52450B/sr unknown
- 2007-04-30 PT PT07724733T patent/PT2024347E/pt unknown
- 2007-04-30 ES ES07724733T patent/ES2391203T3/es active Active
- 2007-04-30 WO PCT/EP2007/003806 patent/WO2007131622A1/de not_active Ceased
- 2007-04-30 PL PL07724733T patent/PL2024347T3/pl unknown
- 2007-04-30 EP EP07724733A patent/EP2024347B1/de active Active
- 2007-04-30 CN CN2007800162659A patent/CN101437805B/zh not_active Expired - Fee Related
- 2007-04-30 NZ NZ572692A patent/NZ572692A/en not_active IP Right Cessation
- 2007-04-30 RU RU2008148838/04A patent/RU2434003C2/ru not_active IP Right Cessation
- 2007-04-30 DK DK07724733.6T patent/DK2024347T3/da active
- 2007-04-30 CA CA002651660A patent/CA2651660A1/en not_active Abandoned
- 2007-04-30 KR KR1020087027644A patent/KR20090006846A/ko not_active Ceased
- 2007-04-30 AU AU2007250213A patent/AU2007250213B2/en not_active Expired - Fee Related
- 2007-04-30 BR BRPI0711448-6A patent/BRPI0711448A2/pt not_active IP Right Cessation
- 2007-04-30 SI SI200731028T patent/SI2024347T1/sl unknown
- 2007-05-09 TW TW096116362A patent/TW200812987A/zh unknown
- 2007-05-09 AR ARP070102008A patent/AR060990A1/es not_active Application Discontinuation
- 2007-05-10 UY UY30338A patent/UY30338A1/es not_active Application Discontinuation
-
2008
- 2008-10-06 ZA ZA200808490A patent/ZA200808490B/xx unknown
- 2008-10-30 CO CO08116211A patent/CO6241107A2/es not_active Application Discontinuation
- 2008-11-05 MA MA31362A patent/MA30402B1/fr unknown
- 2008-11-09 IL IL195179A patent/IL195179A0/en unknown
- 2008-11-10 US US12/267,896 patent/US20090149519A1/en not_active Abandoned
- 2008-12-04 NO NO20085068A patent/NO20085068L/no not_active Application Discontinuation
-
2012
- 2012-10-12 CY CY20121100941T patent/CY1113177T1/el unknown
-
2013
- 2013-07-10 US US13/938,627 patent/US8748465B2/en not_active Expired - Fee Related
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2450042A1 (de) * | 1973-10-23 | 1975-04-24 | Lilly Industries Ltd | Neue benzoxazolderivate und verfahren zu ihrer herstellung |
| SU577992A3 (ru) * | 1973-10-23 | 1977-10-25 | Лилли Индастриз Лимитед (Фирма) | Способ получени производных бензоксазола |
| WO1991019702A1 (en) * | 1990-06-14 | 1991-12-26 | Pfizer Inc. | 3-aryl-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
| RU2080321C1 (ru) * | 1991-09-24 | 1997-05-27 | Берингер Ингельгейм Фармасьютикалз Инк. | Азотсодержащие гетероциклические соединения в виде рацемата или отдельных энантиомеров, являющиеся ингибиторами биосинтеза лейкотриена |
| WO1994008962A1 (en) * | 1992-10-14 | 1994-04-28 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| WO1998040381A1 (en) * | 1997-03-14 | 1998-09-17 | Vertex Pharmaceuticals Incorporated | Inhibitors of impdh enzyme |
| WO2000049005A1 (en) * | 1999-02-16 | 2000-08-24 | Aventis Pharma Limited | Bicyclic compounds and their use as integrin receptor ligands |
| WO2005070920A1 (en) * | 2004-01-21 | 2005-08-04 | Bristol-Myers Squibb Company | Amino-benzazoles as p2y1 receptor inhibitors |
| WO2005070906A1 (en) * | 2004-01-21 | 2005-08-04 | Novartis Ag | Organic compounds |
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| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20140501 |