RU2424824C2 - Комплекс амфифильный полимер-pdgf - Google Patents

Комплекс амфифильный полимер-pdgf Download PDF

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Publication number
RU2424824C2
RU2424824C2 RU2008116585/05A RU2008116585A RU2424824C2 RU 2424824 C2 RU2424824 C2 RU 2424824C2 RU 2008116585/05 A RU2008116585/05 A RU 2008116585/05A RU 2008116585 A RU2008116585 A RU 2008116585A RU 2424824 C2 RU2424824 C2 RU 2424824C2
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RU
Russia
Prior art keywords
pdgf
complex
complex according
amphiphilic polymer
group
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RU2008116585/05A
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English (en)
Russian (ru)
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RU2008116585A (ru
Inventor
Ги ДЮБРЕК (FR)
Ги ДЮБРЕК
Латифа ДАРИ-КОРРЕЯ (FR)
Латифа ДАРИ-КОРРЕЯ
Жозе КОРРЕЯ (FR)
Жозе КОРРЕЯ
Давид ДЮРАШЕ (FR)
Давид ДЮРАШЕ
Реми СУЛА (FR)
Реми СУЛА
Оливье СУЛА (FR)
Оливье СУЛА
Жерар СУЛА (FR)
Жерар СУЛА
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Адосиа
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Publication of RU2424824C2 publication Critical patent/RU2424824C2/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1858Platelet-derived growth factor [PDGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
RU2008116585/05A 2005-09-26 2006-09-26 Комплекс амфифильный полимер-pdgf RU2424824C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0509803A FR2891149B1 (fr) 2005-09-26 2005-09-26 Composition pharmaceutique a action cicatrisante comprenant un derive de dextrane soluble et un facteur de croissance derive des plaquettes.
FR0509803 2005-09-26

Publications (2)

Publication Number Publication Date
RU2008116585A RU2008116585A (ru) 2009-11-10
RU2424824C2 true RU2424824C2 (ru) 2011-07-27

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RU2008116585/05A RU2424824C2 (ru) 2005-09-26 2006-09-26 Комплекс амфифильный полимер-pdgf

Country Status (17)

Country Link
US (3) US20070254828A1 (enExample)
EP (2) EP1940449A2 (enExample)
JP (1) JP5438968B2 (enExample)
KR (1) KR101506593B1 (enExample)
CN (3) CN101316607A (enExample)
AU (1) AU2006293613B2 (enExample)
BR (1) BRPI0616439A2 (enExample)
CA (1) CA2623529C (enExample)
DK (1) DK1940448T3 (enExample)
ES (1) ES2406229T3 (enExample)
FR (1) FR2891149B1 (enExample)
IL (1) IL190400A (enExample)
PL (1) PL1940448T3 (enExample)
PT (1) PT1940448E (enExample)
RU (1) RU2424824C2 (enExample)
WO (2) WO2007034321A2 (enExample)
ZA (2) ZA200803500B (enExample)

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FR2860516B1 (fr) * 2003-10-03 2006-01-13 Flamel Tech Sa Homopolyaminoacides telecheliques fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques
FR2862536B1 (fr) * 2003-11-21 2007-11-23 Flamel Tech Sa Formulations pharmaceutiques pour la liberation prolongee de principe(s) actif(s), ainsi que leurs applications notamment therapeutiques
FR2914305B1 (fr) * 2007-03-29 2009-07-03 Proteins & Peptides Man Dextran fonctionnalise par des amino-acides hydrophobes.
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FR2908414B1 (fr) 2006-11-13 2012-01-20 Centre Nat Rech Scient Immobilisation de proteines membranaires sur un support par l'intermediaire d'une molecule amphiphile
KR20150072458A (ko) 2006-11-15 2015-06-29 코다 테라퓨틱스, 인크. 상처 치유를 위한 개선 방법 및 조성물
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KR20110014588A (ko) * 2008-04-14 2011-02-11 아도시아 성장인자/양친매성 중합체 복합체, 가용성 양이온 염 및 유기 지지체를 포함하는 골형성 조성물
FR2934999B1 (fr) * 2008-08-13 2011-07-29 Adocia Polysaccharides fonctionnalises par des derives du tryptophane
BRPI0913684A2 (pt) * 2008-09-26 2015-10-20 Adocia complexo composto por um polissacarídeo substituído por um triptofano ou um derivado de triptofano a partir de uma proteína ligadora à heparina, composição farmacêutica e seus usos
US8426382B2 (en) * 2008-10-06 2013-04-23 Adocia Polysaccharides comprising carboxyl functional groups substituted by a hydrophobic alcohol derivative
FR2936800B1 (fr) * 2008-10-06 2010-12-31 Adocia Polysaccharide comportant des groupes fonctionnels carboxyles substitues par un derive d'alcool hydrophobe
US9018190B2 (en) 2009-03-27 2015-04-28 Adocia Functionalized oligosaccharides
FR2943538B1 (fr) * 2009-03-27 2011-05-20 Adocia Formulation a action rapide d'insuline recombinante humaine
FR2958646B1 (fr) * 2010-04-07 2012-05-18 Adocia Polysaccharides comportant des groupes fonctionnels carboxyles substitues par un derive d'acide hydrophobe.
JP5950458B2 (ja) * 2010-02-09 2016-07-13 アドシア 少なくとも3価のスペーサーにより保有される少なくとも2つの疎水性基により官能化されたアニオン性多糖類
FR2966248B1 (fr) 2010-10-18 2020-05-01 Centre National De La Recherche Scientifique (Cnrs) Procede de fonctionnalisation de surfaces pour la detection d'analytes
WO2012153071A2 (fr) * 2011-05-10 2012-11-15 Adocia Polysaccharides à degré de fonctionnalisation modulable
US20130231281A1 (en) 2011-11-02 2013-09-05 Adocia Rapid acting insulin formulation comprising an oligosaccharide
KR101466511B1 (ko) * 2012-11-12 2014-11-27 성균관대학교산학협력단 저산소증 관련 질환의 진단 및 치료용 저산소 감응형 나노입자
KR102367083B1 (ko) 2012-11-13 2022-02-24 아도시아 치환된 음이온성 화합물을 포함하는 속효성 인슐린 제형
CN104903341B (zh) * 2012-11-13 2020-04-21 阿道恰公司 由离散数个糖单元组成的骨架组成的经取代阴离子化合物
US9795678B2 (en) 2014-05-14 2017-10-24 Adocia Fast-acting insulin composition comprising a substituted anionic compound and a polyanionic compound
FR3020947B1 (fr) 2014-05-14 2018-08-31 Adocia Composition aqueuse comprenant au moins une proteine et un agent solubilisant, sa preparation et ses utilisations
EP4491184A3 (en) 2014-08-22 2025-03-26 Auckland Uniservices Limited Channel modulators
FR3025428A1 (fr) * 2014-09-08 2016-03-11 Adocia Composition pharmaceutique stable comprenant du pdgf
FR3043557B1 (fr) 2015-11-16 2019-05-31 Adocia Composition a action rapide d'insuline comprenant un citrate substitue
CN106188649B (zh) * 2016-07-04 2019-06-25 宁波国际材料基因工程研究院有限公司 一种药物缓释载体水凝胶及其制备方法
CN111171174B (zh) * 2020-01-14 2022-02-01 上海图珐医药科技有限公司 葡聚糖衍生物及其制备方法和用于制备药剂的附加剂
CN111253569B (zh) * 2020-02-26 2021-06-01 山东大学 一种聚合物、其制剂及其制备方法和应用

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WO2000076452A2 (fr) * 1999-06-16 2000-12-21 Biodex Compositions pharmaceutiques a action cicatrisante ou anti-complementaire comprenant un derive de dextrane
WO2000076562A1 (fr) * 1999-06-11 2000-12-21 Biodex Biomateriau a base d'un derive de dextrane insolubilise et d'un facteur de croissance
RU2174985C2 (ru) * 1995-06-22 2001-10-20 Геркулес Инкорпорейтед Полисахарид с привитым антиоксидантом и способ его получения
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Publication number Priority date Publication date Assignee Title
RU2135212C1 (ru) * 1993-01-22 1999-08-27 Акордис Файбэс (Холдингс) Лимитед Материал для перевязки ран, способы лечения травматической, хирургической или хронической раны, с поверхности которой сочатся выделения (варианты)
RU2174985C2 (ru) * 1995-06-22 2001-10-20 Геркулес Инкорпорейтед Полисахарид с привитым антиоксидантом и способ его получения
WO2000076562A1 (fr) * 1999-06-11 2000-12-21 Biodex Biomateriau a base d'un derive de dextrane insolubilise et d'un facteur de croissance
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EP1369136A1 (en) * 2002-06-05 2003-12-10 Ethicon, Inc. Amphiphilic polymers for medical applications

Also Published As

Publication number Publication date
PT1940448E (pt) 2013-04-15
WO2007034320A3 (fr) 2007-10-04
EP1940448A2 (fr) 2008-07-09
WO2007034321A3 (fr) 2007-10-04
RU2008116585A (ru) 2009-11-10
EP1940448B1 (fr) 2013-03-06
CN103203023A (zh) 2013-07-17
ZA200902008B (en) 2010-09-29
FR2891149B1 (fr) 2007-11-30
ES2406229T3 (es) 2013-06-06
JP2009509952A (ja) 2009-03-12
ZA200803500B (en) 2012-09-26
JP5438968B2 (ja) 2014-03-12
KR101506593B1 (ko) 2015-03-30
US20090221805A1 (en) 2009-09-03
WO2007034320A2 (fr) 2007-03-29
AU2006293613B2 (en) 2012-05-17
CN101631804B (zh) 2012-11-28
CA2623529C (fr) 2013-12-24
CN101316607A (zh) 2008-12-03
AU2006293613A1 (en) 2007-03-29
CN103203023B (zh) 2016-06-01
US8241620B2 (en) 2012-08-14
US20070254828A1 (en) 2007-11-01
US20110301086A1 (en) 2011-12-08
CN101631804A (zh) 2010-01-20
IL190400A (en) 2015-08-31
WO2007034321A2 (fr) 2007-03-29
PL1940448T3 (pl) 2013-08-30
CA2623529A1 (fr) 2007-03-29
FR2891149A1 (fr) 2007-03-30
KR20080080278A (ko) 2008-09-03
DK1940448T3 (da) 2013-06-03
BRPI0616439A2 (pt) 2011-06-21
EP1940449A2 (fr) 2008-07-09

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Effective date: 20180927