DK1940448T3 - Kompleks af amfifil polymer og PDGF - Google Patents

Kompleks af amfifil polymer og PDGF

Info

Publication number
DK1940448T3
DK1940448T3 DK06808894.7T DK06808894T DK1940448T3 DK 1940448 T3 DK1940448 T3 DK 1940448T3 DK 06808894 T DK06808894 T DK 06808894T DK 1940448 T3 DK1940448 T3 DK 1940448T3
Authority
DK
Denmark
Prior art keywords
pdgf
amphiphilic polymer
polymer complex
complex
amphiphilic
Prior art date
Application number
DK06808894.7T
Other languages
Danish (da)
English (en)
Inventor
Guy Dubreucq
Latifa Dahri-Correia
Jose Correia
David Duracher
Remi Soula
Olivier Soula
Gerard Soula
Original Assignee
Adocia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adocia filed Critical Adocia
Application granted granted Critical
Publication of DK1940448T3 publication Critical patent/DK1940448T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1858Platelet-derived growth factor [PDGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DK06808894.7T 2005-09-26 2006-09-26 Kompleks af amfifil polymer og PDGF DK1940448T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0509803A FR2891149B1 (fr) 2005-09-26 2005-09-26 Composition pharmaceutique a action cicatrisante comprenant un derive de dextrane soluble et un facteur de croissance derive des plaquettes.
PCT/IB2006/002666 WO2007034320A2 (fr) 2005-09-26 2006-09-26 Complexe polymere amphiphile-pdgf

Publications (1)

Publication Number Publication Date
DK1940448T3 true DK1940448T3 (da) 2013-06-03

Family

ID=36685952

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06808894.7T DK1940448T3 (da) 2005-09-26 2006-09-26 Kompleks af amfifil polymer og PDGF

Country Status (17)

Country Link
US (3) US20090221805A1 (enExample)
EP (2) EP1940449A2 (enExample)
JP (1) JP5438968B2 (enExample)
KR (1) KR101506593B1 (enExample)
CN (3) CN101316607A (enExample)
AU (1) AU2006293613B2 (enExample)
BR (1) BRPI0616439A2 (enExample)
CA (1) CA2623529C (enExample)
DK (1) DK1940448T3 (enExample)
ES (1) ES2406229T3 (enExample)
FR (1) FR2891149B1 (enExample)
IL (1) IL190400A (enExample)
PL (1) PL1940448T3 (enExample)
PT (1) PT1940448E (enExample)
RU (1) RU2424824C2 (enExample)
WO (2) WO2007034321A2 (enExample)
ZA (2) ZA200803500B (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2822834B1 (fr) * 2001-04-02 2005-02-25 Flamel Tech Sa Suspension colloidale de nanoparticules a base de copolymeres amphiphile pour la vectorisation de principes actifs et leur mode de preparation
FR2840614B1 (fr) 2002-06-07 2004-08-27 Flamel Tech Sa Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques
FR2843117B1 (fr) * 2002-07-30 2004-10-15 Flamel Tech Sa Polyaminoacides fonctionnalises par au moins un groupement hydrophobe et leurs applications notamment therapeutiques
FR2860516B1 (fr) * 2003-10-03 2006-01-13 Flamel Tech Sa Homopolyaminoacides telecheliques fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques
FR2862536B1 (fr) * 2003-11-21 2007-11-23 Flamel Tech Sa Formulations pharmaceutiques pour la liberation prolongee de principe(s) actif(s), ainsi que leurs applications notamment therapeutiques
FR2914305B1 (fr) * 2007-03-29 2009-07-03 Proteins & Peptides Man Dextran fonctionnalise par des amino-acides hydrophobes.
US20120041079A1 (en) * 2006-09-26 2012-02-16 Adocia Dextran functionalized by hydrophobic amino acids
FR2908414B1 (fr) 2006-11-13 2012-01-20 Centre Nat Rech Scient Immobilisation de proteines membranaires sur un support par l'intermediaire d'une molecule amphiphile
JP5960944B2 (ja) 2006-11-15 2016-08-02 コーダ セラピューティクス, インコーポレイテッド 創傷治癒のための改善された方法および組成物
FR2914191A1 (fr) * 2007-03-29 2008-10-03 Proteins & Peptides Man Composition angiogenique.
FR2919188B1 (fr) * 2007-07-27 2010-02-26 Proteins & Peptides Man Complexes entre un polymere amphiphile et une proteine osteogenique appartenant a la famille des bmps
AU2009237414A1 (en) * 2008-04-14 2009-10-22 Adocia Osteogenic composition including a complex growth factor/amphiphilic polymer, a soluble cation salt, and an organic substrate
FR2934999B1 (fr) * 2008-08-13 2011-07-29 Adocia Polysaccharides fonctionnalises par des derives du tryptophane
CN102196822A (zh) * 2008-09-26 2011-09-21 阿道恰公司 由多糖和hbp构成的复合物
US8426382B2 (en) * 2008-10-06 2013-04-23 Adocia Polysaccharides comprising carboxyl functional groups substituted by a hydrophobic alcohol derivative
FR2936800B1 (fr) * 2008-10-06 2010-12-31 Adocia Polysaccharide comportant des groupes fonctionnels carboxyles substitues par un derive d'alcool hydrophobe
FR2943538B1 (fr) * 2009-03-27 2011-05-20 Adocia Formulation a action rapide d'insuline recombinante humaine
US9018190B2 (en) 2009-03-27 2015-04-28 Adocia Functionalized oligosaccharides
FR2958646B1 (fr) * 2010-04-07 2012-05-18 Adocia Polysaccharides comportant des groupes fonctionnels carboxyles substitues par un derive d'acide hydrophobe.
WO2011098962A2 (fr) * 2010-02-09 2011-08-18 Adocia Polysaccharides anioniques fonctionnalisés par au moins deux groupements hydrophobes portés par un spacer au moins trivalent
FR2966248B1 (fr) 2010-10-18 2020-05-01 Centre National De La Recherche Scientifique (Cnrs) Procede de fonctionnalisation de surfaces pour la detection d'analytes
US20120295833A1 (en) * 2011-05-10 2012-11-22 Adocia Polysaccharides having an adjustable degree of functionalization
US20130231281A1 (en) 2011-11-02 2013-09-05 Adocia Rapid acting insulin formulation comprising an oligosaccharide
KR101466511B1 (ko) * 2012-11-12 2014-11-27 성균관대학교산학협력단 저산소증 관련 질환의 진단 및 치료용 저산소 감응형 나노입자
ES2670969T3 (es) 2012-11-13 2018-06-04 Adocia Formulación de acción rápida de insulina que comprende un compuesto aniónico sustituido
CN111494638A (zh) * 2012-11-13 2020-08-07 阿道恰公司 由离散数个糖单元组成的骨架组成的经取代阴离子化合物
US9795678B2 (en) 2014-05-14 2017-10-24 Adocia Fast-acting insulin composition comprising a substituted anionic compound and a polyanionic compound
FR3020947B1 (fr) 2014-05-14 2018-08-31 Adocia Composition aqueuse comprenant au moins une proteine et un agent solubilisant, sa preparation et ses utilisations
JP6683686B2 (ja) 2014-08-22 2020-04-22 オークランド ユニサービシーズ リミティド チャネル調節剤
FR3025428A1 (fr) * 2014-09-08 2016-03-11 Adocia Composition pharmaceutique stable comprenant du pdgf
FR3043557B1 (fr) 2015-11-16 2019-05-31 Adocia Composition a action rapide d'insuline comprenant un citrate substitue
CN106188649B (zh) * 2016-07-04 2019-06-25 宁波国际材料基因工程研究院有限公司 一种药物缓释载体水凝胶及其制备方法
CN111171174B (zh) * 2020-01-14 2022-02-01 上海图珐医药科技有限公司 葡聚糖衍生物及其制备方法和用于制备药剂的附加剂
CN111253569B (zh) * 2020-02-26 2021-06-01 山东大学 一种聚合物、其制剂及其制备方法和应用

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US169120A (en) * 1875-10-26 Improvement in machines for bending scythe-snaths
US183282A (en) * 1876-10-17 Improvement in striping implements
US2808405A (en) * 1955-03-11 1957-10-01 Ohio Commw Eng Co Acylated amino acid esters of dextran products and method of making same
US4766073A (en) 1985-02-25 1988-08-23 Zymogenetics Inc. Expression of biologically active PDGF analogs in eucaryotic cells
US4717717A (en) 1986-11-05 1988-01-05 Ethicon, Inc. Stabilized compositions containing epidermal growth factor
US5705485A (en) * 1987-09-18 1998-01-06 Ethicon, Inc. Gel formulations containing growth factors
US5457093A (en) * 1987-09-18 1995-10-10 Ethicon, Inc. Gel formulations containing growth factors
AU8294991A (en) 1990-07-23 1992-02-18 Zymogenetics Inc. Protease resistant pdgf and methods of use
US5234908A (en) * 1991-04-12 1993-08-10 Creative Biomolecules, Inc. Method of treating gastrointestinal ulcers with platelet derived growth factor
JPH0543453A (ja) * 1991-08-20 1993-02-23 Sumitomo Pharmaceut Co Ltd 創傷治癒促進用局所用徐放性製剤
AU3062392A (en) 1991-11-04 1993-06-07 Novo Nordisk A/S Pdgf gel formulation
DE4136324A1 (de) * 1991-11-05 1993-05-13 Hoechst Ag Dextranderivate als adsorptionsmittel fuer gallensaeuren, mit gallensaeuren beladene dextranderivate und verfahren zu deren herstellung sowie deren anwendung als arzneimittel
GB9301258D0 (en) * 1993-01-22 1993-03-17 Courtaulds Plc Use of absorbent fibre
US5612321A (en) * 1995-06-22 1997-03-18 Hercules Incorporated Antioxidant grafted polysaccharides
CA2192725C (en) * 1995-12-28 2004-04-20 Kenji Tsujihara Camptothecin derivatives
WO1998026080A1 (en) 1996-12-13 1998-06-18 Chiron Corporation Method for expression of heterologous proteins in yeast
AU7466998A (en) * 1997-04-14 1998-11-11 Byron E. Anderson Method and material for inhibiting complement
FR2772382B1 (fr) * 1997-12-11 2000-03-03 Solutions Derives de dextrane, leur procede de preparation et leurs applications comme medicaments a action biologique specifique
FR2794649B1 (fr) * 1999-06-11 2003-04-11 Solutions Biomateriau a base d'un derive de dextrane insolubilise et d'un facteur de croissance, son procede de preparation et ses applications
FR2794976B1 (fr) * 1999-06-16 2004-05-07 Solutions Compositions pharmaceutiques a action cicatrisante ou anti-complementaire comprenant un derive de dextrane
JP4434584B2 (ja) * 2001-01-26 2010-03-17 ジェネティックス ファーマシューティカルズ, インク. 血管新生を促進する方法及び組成物
DE10140623A1 (de) * 2001-08-18 2003-03-06 Nawa Heilmittel Gmbh Pharmazeutisches Präparat zur Behandlung von Wunden
US7368125B2 (en) * 2002-06-05 2008-05-06 Ethicon, Inc. Amphiphilic polymers for medical applications
FR2840614B1 (fr) * 2002-06-07 2004-08-27 Flamel Tech Sa Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques
CN1506112A (zh) * 2002-12-09 2004-06-23 北京金赛狮生物制药技术开发有限责任 重组血小板源生长因子的水凝胶制剂
CN1506113A (zh) * 2002-12-09 2004-06-23 北京金赛狮生物制药技术开发有限责任 重组血小板源生长因子水凝胶制剂的制备方法
CN1508259A (zh) * 2002-12-19 2004-06-30 北京金赛狮生物制药技术开发有限责任 重组人血小板源生长因子的发酵方法
WO2005075455A2 (en) 2004-01-30 2005-08-18 Euro-Celtique S.A. Methods for making 4-tetrazolyl-4-phenylpiperidine compounds
WO2007013100A1 (en) 2005-07-26 2007-02-01 Virchow Biotech Private Limited Gel formulation comprising platelet derived growth factor
WO2007116143A1 (fr) * 2006-04-07 2007-10-18 Adocia Polysaccharides bifonctionnalises

Also Published As

Publication number Publication date
BRPI0616439A2 (pt) 2011-06-21
FR2891149A1 (fr) 2007-03-30
IL190400A (en) 2015-08-31
ZA200902008B (en) 2010-09-29
EP1940448B1 (fr) 2013-03-06
WO2007034320A3 (fr) 2007-10-04
KR101506593B1 (ko) 2015-03-30
PL1940448T3 (pl) 2013-08-30
RU2008116585A (ru) 2009-11-10
WO2007034321A2 (fr) 2007-03-29
EP1940449A2 (fr) 2008-07-09
ZA200803500B (en) 2012-09-26
JP5438968B2 (ja) 2014-03-12
CN103203023A (zh) 2013-07-17
CN101316607A (zh) 2008-12-03
FR2891149B1 (fr) 2007-11-30
KR20080080278A (ko) 2008-09-03
CN101631804A (zh) 2010-01-20
RU2424824C2 (ru) 2011-07-27
AU2006293613B2 (en) 2012-05-17
CN103203023B (zh) 2016-06-01
ES2406229T3 (es) 2013-06-06
CA2623529A1 (fr) 2007-03-29
US20090221805A1 (en) 2009-09-03
US20110301086A1 (en) 2011-12-08
CA2623529C (fr) 2013-12-24
AU2006293613A1 (en) 2007-03-29
EP1940448A2 (fr) 2008-07-09
WO2007034320A2 (fr) 2007-03-29
CN101631804B (zh) 2012-11-28
PT1940448E (pt) 2013-04-15
US8241620B2 (en) 2012-08-14
JP2009509952A (ja) 2009-03-12
US20070254828A1 (en) 2007-11-01
WO2007034321A3 (fr) 2007-10-04

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