ZA200803500B - Pdgf amphiphillic polymer complex - Google Patents

Pdgf amphiphillic polymer complex

Info

Publication number
ZA200803500B
ZA200803500B ZA2008/03500A ZA200803500A ZA200803500B ZA 200803500 B ZA200803500 B ZA 200803500B ZA 2008/03500 A ZA2008/03500 A ZA 2008/03500A ZA 200803500 A ZA200803500 A ZA 200803500A ZA 200803500 B ZA200803500 B ZA 200803500B
Authority
ZA
South Africa
Prior art keywords
amphiphillic
pdgf
polymer complex
polymer
complex
Prior art date
Application number
ZA2008/03500A
Other languages
English (en)
Inventor
Guy Dubreucq
Jose Correia
Remi Soula
Gerard Soula
Correia Latifa Dahri
David Duracher
Olivier Soula
Original Assignee
Adocia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adocia filed Critical Adocia
Publication of ZA200803500B publication Critical patent/ZA200803500B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Indole Compounds (AREA)
ZA2008/03500A 2005-09-26 2008-04-21 Pdgf amphiphillic polymer complex ZA200803500B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0509803A FR2891149B1 (fr) 2005-09-26 2005-09-26 Composition pharmaceutique a action cicatrisante comprenant un derive de dextrane soluble et un facteur de croissance derive des plaquettes.
PCT/IB2006/002666 WO2007034320A2 (fr) 2005-09-26 2006-09-26 Complexe polymere amphiphile-pdgf

Publications (1)

Publication Number Publication Date
ZA200803500B true ZA200803500B (en) 2012-09-26

Family

ID=36685952

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA2008/03500A ZA200803500B (en) 2005-09-26 2008-04-21 Pdgf amphiphillic polymer complex
ZA200902008A ZA200902008B (en) 2005-09-26 2009-03-20 Dextran functionalized with hydrophobic amino acids

Family Applications After (1)

Application Number Title Priority Date Filing Date
ZA200902008A ZA200902008B (en) 2005-09-26 2009-03-20 Dextran functionalized with hydrophobic amino acids

Country Status (17)

Country Link
US (3) US20090221805A1 (enExample)
EP (2) EP1940448B1 (enExample)
JP (1) JP5438968B2 (enExample)
KR (1) KR101506593B1 (enExample)
CN (3) CN101316607A (enExample)
AU (1) AU2006293613B2 (enExample)
BR (1) BRPI0616439A2 (enExample)
CA (1) CA2623529C (enExample)
DK (1) DK1940448T3 (enExample)
ES (1) ES2406229T3 (enExample)
FR (1) FR2891149B1 (enExample)
IL (1) IL190400A (enExample)
PL (1) PL1940448T3 (enExample)
PT (1) PT1940448E (enExample)
RU (1) RU2424824C2 (enExample)
WO (2) WO2007034321A2 (enExample)
ZA (2) ZA200803500B (enExample)

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FR2822834B1 (fr) * 2001-04-02 2005-02-25 Flamel Tech Sa Suspension colloidale de nanoparticules a base de copolymeres amphiphile pour la vectorisation de principes actifs et leur mode de preparation
FR2840614B1 (fr) 2002-06-07 2004-08-27 Flamel Tech Sa Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques
FR2843117B1 (fr) * 2002-07-30 2004-10-15 Flamel Tech Sa Polyaminoacides fonctionnalises par au moins un groupement hydrophobe et leurs applications notamment therapeutiques
FR2860516B1 (fr) * 2003-10-03 2006-01-13 Flamel Tech Sa Homopolyaminoacides telecheliques fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques
FR2862536B1 (fr) * 2003-11-21 2007-11-23 Flamel Tech Sa Formulations pharmaceutiques pour la liberation prolongee de principe(s) actif(s), ainsi que leurs applications notamment therapeutiques
FR2914305B1 (fr) * 2007-03-29 2009-07-03 Proteins & Peptides Man Dextran fonctionnalise par des amino-acides hydrophobes.
US20120041079A1 (en) * 2006-09-26 2012-02-16 Adocia Dextran functionalized by hydrophobic amino acids
FR2908414B1 (fr) 2006-11-13 2012-01-20 Centre Nat Rech Scient Immobilisation de proteines membranaires sur un support par l'intermediaire d'une molecule amphiphile
RU2542471C2 (ru) 2006-11-15 2015-02-20 Коуда Терапьютикс, Инк. Улучшенные способы и композиции для заживления ран
FR2914191A1 (fr) * 2007-03-29 2008-10-03 Proteins & Peptides Man Composition angiogenique.
FR2919188B1 (fr) * 2007-07-27 2010-02-26 Proteins & Peptides Man Complexes entre un polymere amphiphile et une proteine osteogenique appartenant a la famille des bmps
US20090291114A1 (en) * 2008-04-14 2009-11-26 Adocia Osteogenic composition comprising a growth factor/amphiphilic polymer complex, a soluble cation salt and an organic support
FR2934999B1 (fr) * 2008-08-13 2011-07-29 Adocia Polysaccharides fonctionnalises par des derives du tryptophane
BRPI0913684A2 (pt) * 2008-09-26 2015-10-20 Adocia complexo composto por um polissacarídeo substituído por um triptofano ou um derivado de triptofano a partir de uma proteína ligadora à heparina, composição farmacêutica e seus usos
FR2936800B1 (fr) * 2008-10-06 2010-12-31 Adocia Polysaccharide comportant des groupes fonctionnels carboxyles substitues par un derive d'alcool hydrophobe
US8426382B2 (en) * 2008-10-06 2013-04-23 Adocia Polysaccharides comprising carboxyl functional groups substituted by a hydrophobic alcohol derivative
FR2943538B1 (fr) * 2009-03-27 2011-05-20 Adocia Formulation a action rapide d'insuline recombinante humaine
US9018190B2 (en) 2009-03-27 2015-04-28 Adocia Functionalized oligosaccharides
FR2958646B1 (fr) * 2010-04-07 2012-05-18 Adocia Polysaccharides comportant des groupes fonctionnels carboxyles substitues par un derive d'acide hydrophobe.
WO2011098962A2 (fr) * 2010-02-09 2011-08-18 Adocia Polysaccharides anioniques fonctionnalisés par au moins deux groupements hydrophobes portés par un spacer au moins trivalent
FR2966248B1 (fr) 2010-10-18 2020-05-01 Centre National De La Recherche Scientifique (Cnrs) Procede de fonctionnalisation de surfaces pour la detection d'analytes
US20120295833A1 (en) * 2011-05-10 2012-11-22 Adocia Polysaccharides having an adjustable degree of functionalization
US20130231281A1 (en) 2011-11-02 2013-09-05 Adocia Rapid acting insulin formulation comprising an oligosaccharide
KR101466511B1 (ko) * 2012-11-12 2014-11-27 성균관대학교산학협력단 저산소증 관련 질환의 진단 및 치료용 저산소 감응형 나노입자
EA201590937A1 (ru) * 2012-11-13 2016-04-29 Адосиа Замещенные анионные соединения, имеющие скелет, образованный из небольшого числа сахаридных звеньев
EP2919804B1 (fr) * 2012-11-13 2018-01-31 Adocia Formulation à action rapide d'insuline comprenant un composé anionique substitué
US9795678B2 (en) 2014-05-14 2017-10-24 Adocia Fast-acting insulin composition comprising a substituted anionic compound and a polyanionic compound
FR3020947B1 (fr) 2014-05-14 2018-08-31 Adocia Composition aqueuse comprenant au moins une proteine et un agent solubilisant, sa preparation et ses utilisations
WO2016029191A2 (en) 2014-08-22 2016-02-25 Auckland Uniservices Limited Channel modulators
FR3025428A1 (fr) 2014-09-08 2016-03-11 Adocia Composition pharmaceutique stable comprenant du pdgf
FR3043557B1 (fr) 2015-11-16 2019-05-31 Adocia Composition a action rapide d'insuline comprenant un citrate substitue
CN106188649B (zh) * 2016-07-04 2019-06-25 宁波国际材料基因工程研究院有限公司 一种药物缓释载体水凝胶及其制备方法
CN111171174B (zh) * 2020-01-14 2022-02-01 上海图珐医药科技有限公司 葡聚糖衍生物及其制备方法和用于制备药剂的附加剂
CN111253569B (zh) * 2020-02-26 2021-06-01 山东大学 一种聚合物、其制剂及其制备方法和应用
US12667586B2 (en) 2023-03-07 2026-06-30 Glaukos Corporation Treatments for ocular surface disorders

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Also Published As

Publication number Publication date
WO2007034321A2 (fr) 2007-03-29
EP1940449A2 (fr) 2008-07-09
AU2006293613A1 (en) 2007-03-29
BRPI0616439A2 (pt) 2011-06-21
CN101631804A (zh) 2010-01-20
DK1940448T3 (da) 2013-06-03
FR2891149B1 (fr) 2007-11-30
RU2424824C2 (ru) 2011-07-27
JP2009509952A (ja) 2009-03-12
US20070254828A1 (en) 2007-11-01
RU2008116585A (ru) 2009-11-10
WO2007034320A3 (fr) 2007-10-04
AU2006293613B2 (en) 2012-05-17
CN101316607A (zh) 2008-12-03
PT1940448E (pt) 2013-04-15
WO2007034321A3 (fr) 2007-10-04
CA2623529C (fr) 2013-12-24
ES2406229T3 (es) 2013-06-06
KR20080080278A (ko) 2008-09-03
CA2623529A1 (fr) 2007-03-29
WO2007034320A2 (fr) 2007-03-29
PL1940448T3 (pl) 2013-08-30
CN103203023B (zh) 2016-06-01
JP5438968B2 (ja) 2014-03-12
CN101631804B (zh) 2012-11-28
US20110301086A1 (en) 2011-12-08
IL190400A (en) 2015-08-31
FR2891149A1 (fr) 2007-03-30
KR101506593B1 (ko) 2015-03-30
EP1940448B1 (fr) 2013-03-06
ZA200902008B (en) 2010-09-29
US20090221805A1 (en) 2009-09-03
CN103203023A (zh) 2013-07-17
EP1940448A2 (fr) 2008-07-09
US8241620B2 (en) 2012-08-14

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