RU2372893C2 - Содержащий фармацевтический агент состав с покрытием - Google Patents

Содержащий фармацевтический агент состав с покрытием Download PDF

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Publication number
RU2372893C2
RU2372893C2 RU2006118689/15A RU2006118689A RU2372893C2 RU 2372893 C2 RU2372893 C2 RU 2372893C2 RU 2006118689/15 A RU2006118689/15 A RU 2006118689/15A RU 2006118689 A RU2006118689 A RU 2006118689A RU 2372893 C2 RU2372893 C2 RU 2372893C2
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RU
Russia
Prior art keywords
salt
active ingredient
coating
film
polymer
Prior art date
Application number
RU2006118689/15A
Other languages
English (en)
Russian (ru)
Other versions
RU2006118689A (ru
Inventor
Карин КЛОККЕРС (DE)
Карин КЛОККЕРС
Марион ЦЕЛЛЬНЕР (DE)
Марион ЦЕЛЛЬНЕР
Томас РИЛЛЬМАНН (DE)
Томас РИЛЛЬМАНН
Андреас ДАУЕР (DE)
Андреас ДАУЕР
Original Assignee
Хексал Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34553325&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RU2372893(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE2003151301 external-priority patent/DE10351301A1/de
Priority claimed from DE200410014828 external-priority patent/DE102004014828A1/de
Application filed by Хексал Аг filed Critical Хексал Аг
Publication of RU2006118689A publication Critical patent/RU2006118689A/ru
Application granted granted Critical
Publication of RU2372893C2 publication Critical patent/RU2372893C2/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU2006118689/15A 2003-10-31 2004-10-28 Содержащий фармацевтический агент состав с покрытием RU2372893C2 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE10351301.9 2003-10-31
DE2003151301 DE10351301A1 (de) 2003-10-31 2003-10-31 Retardierte Dosisform aus mehreren Einzeleinheiten
DE200410014828 DE102004014828A1 (de) 2004-03-24 2004-03-24 Pharmazeutische wirkstoffhaltige Formulierung mit Überzug
DE102004014828.7 2004-03-24

Publications (2)

Publication Number Publication Date
RU2006118689A RU2006118689A (ru) 2007-12-20
RU2372893C2 true RU2372893C2 (ru) 2009-11-20

Family

ID=34553325

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2006118689/15A RU2372893C2 (ru) 2003-10-31 2004-10-28 Содержащий фармацевтический агент состав с покрытием

Country Status (12)

Country Link
US (1) US20080254112A1 (enExample)
EP (1) EP1677766B1 (enExample)
JP (1) JP2007509891A (enExample)
AT (1) ATE549015T1 (enExample)
AU (1) AU2004285284B2 (enExample)
BR (1) BRPI0415557A (enExample)
CA (1) CA2543689A1 (enExample)
MX (1) MXPA06004700A (enExample)
NO (1) NO20062051L (enExample)
NZ (1) NZ547284A (enExample)
RU (1) RU2372893C2 (enExample)
WO (1) WO2005041934A2 (enExample)

Cited By (1)

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US20130287855A1 (en) * 2010-12-14 2013-10-31 Alexandra Fregonese Compositions based on clay and bee pollen, method for preparing same, and nutritional and therapeutic uses thereof

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DE102005024614A1 (de) * 2005-05-25 2006-11-30 Röhm Gmbh Verwendung von Polymermischungen zur Herstellung von überzogenen Arzneiformen sowie Arzneiform mit polymerem Mischüberzug
ATE536864T1 (de) * 2006-02-24 2011-12-15 Teva Pharma Metoprololsuccinat tabletten mit verlängerter freisetzung und verfahren für deren herstellung
SI3103448T1 (sl) * 2006-09-26 2019-11-29 Novartis Ag Farmacevtski sestavek, ki vsebuje modulator S1P
US8367115B2 (en) 2007-08-27 2013-02-05 Asahi Kasei Chemicals Corporation Process for production of crystalline cellulose and tablets containing granules
CN101801357B (zh) * 2007-09-21 2013-08-07 赢创罗姆有限公司 耐受乙醇的影响的pH依赖性受控释放的药物组合物
ES2393805T3 (es) * 2007-09-21 2012-12-28 Evonik Röhm Gmbh Composición farmacéutica de liberación controlada dependiente del pH para compuestos no opioides con resistencia frente a la influencia del etanol
HUE043474T2 (hu) 2008-01-10 2019-08-28 Evonik Roehm Gmbh Bevont gyógyszerészeti vagy gyógyhatású étrend-kiegészítõ készítmény javított pulzáló hatóanyag-felszabadulással
JP2011509266A (ja) * 2008-01-10 2011-03-24 エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング 活性物質の制御放出が促進された、コーティングされた医薬製剤もしくはニュートラシューティカル製剤
CN102119027A (zh) * 2008-06-26 2011-07-06 麦克内尔-Ppc股份有限公司 含有药物活性剂的包衣颗粒
EP2329823A4 (en) 2008-09-03 2013-04-03 Takeda Pharmaceutical PROCESS FOR INCREASING THE ABSORPTION ABILITY OF A PREPARATION AND PREPARATION WITH INCREASED ABSORPTION ABILITY
CN102365083A (zh) * 2009-03-18 2012-02-29 赢创罗姆有限公司 采用包含聚合物混合物和赋形剂的包衣的具有耐乙醇影响的控释药物组合物
KR101571198B1 (ko) * 2009-03-18 2015-11-23 에보니크 룀 게엠베하 중성 비닐 중합체 및 부형제를 포함하는 코팅을 이용하는, 에탄올의 영향에 대한 내성을 갖는 제어 방출 제약 조성물
CN102421423B (zh) 2009-05-12 2014-11-05 Bpsi控股有限责任公司 增强型防潮即释薄膜包衣系统和覆有该包衣的基体
BRPI1007724A2 (pt) * 2009-05-12 2017-09-19 Bpsi Holdings Llc Composição de revestimento seco, suspensão aquosa, substrato oral, método para preparação de dispersão aquosa de revestimento, forma de dosagem oral farmaceuticamente aceitável e método de preparação de formas de dosagem sólidas orais farmaceuticamente aceitáveis
EP2564837B1 (en) 2010-04-30 2019-01-30 Takeda Pharmaceutical Company Limited Enteric tablet
BR112012027794A2 (pt) 2010-04-30 2016-08-02 Takeda Pharmaceutical tablete entérico
ES2583132T3 (es) * 2011-09-16 2016-09-19 Purdue Pharma L.P. Formulaciones de liberación inmediata resistentes a alteración
CA2847611A1 (en) * 2011-09-16 2013-03-21 Purdue Pharma L.P. Tamper resistant pharmaceutical formulations
US20170042806A1 (en) 2015-04-29 2017-02-16 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
EP4013372A4 (en) 2019-08-13 2023-08-30 McCord, Darlene E. NON-ACTIVATED, AMORPHIC, PH-NEUTRAL, TWO-PIECE, BED-SIDE READY SOUND SYSTEM FOR THE TREATMENT OF PATHOGENIC INFECTIONS IN HUMAN AND ANIMAL
JP7482645B2 (ja) * 2020-02-18 2024-05-14 沢井製薬株式会社 核粒子を含む顆粒の製造方法
US12213993B2 (en) 2021-10-25 2025-02-04 Darlene E. McCord Coated medicinal clay compositions, pharmaceutical compositions, and delivery of cation sources and methods of use thereof

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DE3900811A1 (de) * 1989-01-13 1990-07-19 Kali Chemie Pharma Gmbh Neue arzneiform
RU2152821C1 (ru) * 1995-06-07 2000-07-20 Филлипс Петролеум Компани Способ получения композиции макрочастиц

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DE19732903A1 (de) * 1997-07-30 1999-02-04 Falk Pharma Gmbh Pellet-Formulierung zur Behandlung des Intestinaltraktes
ATE252892T1 (de) * 1997-09-11 2003-11-15 Nycomed Danmark Aps Aus mehreren einzeleinheiten zusammengesetzte arzneimittel mit nicht-steroidalen wirkstoffen (nsaids)
CN1195500C (zh) * 1998-05-18 2005-04-06 武田药品工业株式会社 可口腔崩解的片剂
DE19905906A1 (de) * 1999-02-11 2000-08-17 Basf Ag Verwendung von wasserlöslichen oder wasserdispergierbaren Polyether-haltigen Polymerisaten als Überzugsmittel, Bindemittel und/oder filmbildender Hilfsstoff in pharmazeutischen Darreichungsformen
DE19850238A1 (de) * 1998-10-31 2000-05-04 Triple Trian Beteiligungs Gmbh Verfahren und Vorrichtung zur Kompensation von Elektrosmog
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US7897179B2 (en) * 2003-08-06 2011-03-01 Nostrum Pharmaceuticals, Inc. Pharmaceutical composition containing water soluble drug

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Publication number Priority date Publication date Assignee Title
DE3900811A1 (de) * 1989-01-13 1990-07-19 Kali Chemie Pharma Gmbh Neue arzneiform
RU2152821C1 (ru) * 1995-06-07 2000-07-20 Филлипс Петролеум Компани Способ получения композиции макрочастиц

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130287855A1 (en) * 2010-12-14 2013-10-31 Alexandra Fregonese Compositions based on clay and bee pollen, method for preparing same, and nutritional and therapeutic uses thereof
RU2622013C2 (ru) * 2010-12-14 2017-06-08 Лаборатуар Бипрэтт Композиции на основе глины и обножки, способ их получения и их применение в питании и терапевтическом лечении
US9821014B2 (en) * 2010-12-14 2017-11-21 Laboratoire Beepratte Compositions based on clay and beepollen, method for preparing same and nutritional and therapeutic uses thereof

Also Published As

Publication number Publication date
NZ547284A (en) 2009-12-24
BRPI0415557A (pt) 2006-12-26
NO20062051L (no) 2006-07-25
AU2004285284B2 (en) 2010-03-25
ATE549015T1 (de) 2012-03-15
JP2007509891A (ja) 2007-04-19
AU2004285284A1 (en) 2005-05-12
US20080254112A1 (en) 2008-10-16
EP1677766B1 (de) 2012-03-14
MXPA06004700A (es) 2006-07-05
CA2543689A1 (en) 2005-05-12
WO2005041934A3 (de) 2005-12-01
WO2005041934A2 (de) 2005-05-12
RU2006118689A (ru) 2007-12-20
EP1677766A2 (de) 2006-07-12

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20171029