AU2004285284B2 - A process for the preparation of an active-ingredient-containing formulation with a coating - Google Patents

A process for the preparation of an active-ingredient-containing formulation with a coating Download PDF

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Publication number
AU2004285284B2
AU2004285284B2 AU2004285284A AU2004285284A AU2004285284B2 AU 2004285284 B2 AU2004285284 B2 AU 2004285284B2 AU 2004285284 A AU2004285284 A AU 2004285284A AU 2004285284 A AU2004285284 A AU 2004285284A AU 2004285284 B2 AU2004285284 B2 AU 2004285284B2
Authority
AU
Australia
Prior art keywords
process according
active
ingredient
coating
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2004285284A
Other languages
English (en)
Other versions
AU2004285284A1 (en
Inventor
Andreas Dauer
Karin Klokkers
Thomas Rillmann
Marion Zellner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hexal AG
Original Assignee
Hexal AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34553325&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2004285284(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE2003151301 external-priority patent/DE10351301A1/de
Priority claimed from DE200410014828 external-priority patent/DE102004014828A1/de
Application filed by Hexal AG filed Critical Hexal AG
Publication of AU2004285284A1 publication Critical patent/AU2004285284A1/en
Application granted granted Critical
Publication of AU2004285284B2 publication Critical patent/AU2004285284B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2004285284A 2003-10-31 2004-10-28 A process for the preparation of an active-ingredient-containing formulation with a coating Ceased AU2004285284B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE10351301.9 2003-10-31
DE2003151301 DE10351301A1 (de) 2003-10-31 2003-10-31 Retardierte Dosisform aus mehreren Einzeleinheiten
DE200410014828 DE102004014828A1 (de) 2004-03-24 2004-03-24 Pharmazeutische wirkstoffhaltige Formulierung mit Überzug
DE102004014828.7 2004-03-24
PCT/EP2004/012230 WO2005041934A2 (de) 2003-10-31 2004-10-28 Pharmazeutische wirkstoffhaltige formulierung mit überzug

Publications (2)

Publication Number Publication Date
AU2004285284A1 AU2004285284A1 (en) 2005-05-12
AU2004285284B2 true AU2004285284B2 (en) 2010-03-25

Family

ID=34553325

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2004285284A Ceased AU2004285284B2 (en) 2003-10-31 2004-10-28 A process for the preparation of an active-ingredient-containing formulation with a coating

Country Status (12)

Country Link
US (1) US20080254112A1 (enExample)
EP (1) EP1677766B1 (enExample)
JP (1) JP2007509891A (enExample)
AT (1) ATE549015T1 (enExample)
AU (1) AU2004285284B2 (enExample)
BR (1) BRPI0415557A (enExample)
CA (1) CA2543689A1 (enExample)
MX (1) MXPA06004700A (enExample)
NO (1) NO20062051L (enExample)
NZ (1) NZ547284A (enExample)
RU (1) RU2372893C2 (enExample)
WO (1) WO2005041934A2 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005024614A1 (de) * 2005-05-25 2006-11-30 Röhm Gmbh Verwendung von Polymermischungen zur Herstellung von überzogenen Arzneiformen sowie Arzneiform mit polymerem Mischüberzug
US20070202172A1 (en) * 2006-02-24 2007-08-30 Tomer Gold Metoprolol succinate E.R. tablets and methods for their preparation
SI3103448T1 (sl) * 2006-09-26 2019-11-29 Novartis Ag Farmacevtski sestavek, ki vsebuje modulator S1P
JP5242576B2 (ja) 2007-08-27 2013-07-24 旭化成ケミカルズ株式会社 結晶セルロース及び顆粒含有錠の製造方法
MX2010003032A (es) * 2007-09-21 2010-04-09 Evonik R Hm Gmbh Composicion farmaceutica opioide de liberacion controlada ph dependiente con resistencia contra la influencia del etanol.
PL2187875T3 (pl) * 2007-09-21 2013-01-31 Evonik Roehm Gmbh Kompozycja farmaceutyczna o zależnym od pH kontrolowanym uwalnianiu dla nieopioidów z odpornością przed wpływem etanolu
JP2011509266A (ja) * 2008-01-10 2011-03-24 エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング 活性物質の制御放出が促進された、コーティングされた医薬製剤もしくはニュートラシューティカル製剤
KR101571179B1 (ko) * 2008-01-10 2015-11-23 에보니크 룀 게엠베하 증가된 맥동성 활성 물질 방출을 갖는 코팅된 제약학적 또는 건강기능성 제제
EP2309999A1 (en) * 2008-06-26 2011-04-20 McNeil-PPC, Inc. Coated particles containing pharmaceutically active agents
WO2010026993A1 (ja) 2008-09-03 2010-03-11 武田薬品工業株式会社 製剤における吸収性改善方法および吸収性が改善された製剤
US9730899B2 (en) * 2009-03-18 2017-08-15 Evonik Roehm Gmbh Controlled release pharmaceutical composition with resistance against the influence of ethanol employing a coating comprising neutral vinyl polymers and excipients
WO2010105673A1 (en) * 2009-03-18 2010-09-23 Evonik Röhm Gmbh Controlled release pharmaceutical composition with resistance against the influence of ethanol employing a coating comprising a polymer mixture and excipients
BRPI1007725A2 (pt) 2009-05-12 2016-02-16 Bpsi Holdings Llc composição de revestimento de liberação imediata com propriedades melhoradas de barreira à umidade, suspensão aquosa, substrato oral revestido, forma de dosagem oral e método para preparação da mesma
EP2429504A4 (en) * 2009-05-12 2013-05-01 Bpsi Holdings Llc FILM COATINGS WITH DECEPTORS IN FINE PARTICLE SIZES AND SUBSTRATES COATED THEREFOR
US8920840B2 (en) 2010-04-30 2014-12-30 Takeda Pharmaceutical Company Limited Enteric tablet
WO2011136376A1 (ja) 2010-04-30 2011-11-03 武田薬品工業株式会社 腸溶性錠剤
FR2968559B1 (fr) * 2010-12-14 2012-12-28 Alexandra Fregonese Nouvelles compositions a base d'argile et de beepollen, leur procede de preparation et leurs utilisations en nutrition et en therapeutique
ES2641437T3 (es) * 2011-09-16 2017-11-10 Purdue Pharma Lp Formulaciones farmacéuticas resistentes a la manipulación indebida
ES2703688T3 (es) * 2011-09-16 2019-03-12 Purdue Pharma Lp Formulaciones de liberación inmediata resistentes a alteración
US20170042806A1 (en) 2015-04-29 2017-02-16 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
WO2021030550A1 (en) 2019-08-13 2021-02-18 Mccord Darlene E NON-ACTIVATED, AMORPHOUS, pH NEUTRAL, TWO-PART BEDSIDE-READY CLAY DELIVERY SYSTEM THAT TREATS PATHOGEN INFECTIONS IN HUMANS AND ANIMALS
JP7482645B2 (ja) * 2020-02-18 2024-05-14 沢井製薬株式会社 核粒子を含む顆粒の製造方法
EP4423197A4 (en) 2021-10-25 2025-08-27 Darlene E Mccord COATED MEDICINAL CLAY COMPOSITIONS, PHARMACEUTICAL COMPOSITIONS AND DELIVERY OF CATION SOURCES AND METHODS OF USE THEREOF

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3900811A1 (de) * 1989-01-13 1990-07-19 Kali Chemie Pharma Gmbh Neue arzneiform
WO1996037195A1 (de) * 1995-05-24 1996-11-28 Mepha Ag Neue pharmazeutische pelletformulierung
DE19905906A1 (de) * 1999-02-11 2000-08-17 Basf Ag Verwendung von wasserlöslichen oder wasserdispergierbaren Polyether-haltigen Polymerisaten als Überzugsmittel, Bindemittel und/oder filmbildender Hilfsstoff in pharmazeutischen Darreichungsformen
WO2003051340A1 (en) * 2001-12-19 2003-06-26 Astrazeneca Ab New film coating
US20030133983A1 (en) * 1997-07-30 2003-07-17 Dr. Falk Pharma Gmbh. Pellet formulation for the treatment of the intestinal tract

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5110814A (en) * 1989-01-11 1992-05-05 Asta Pharma Ag Azelastine and its salts used to combat psoriasis
CA2177769C (en) * 1995-06-07 1999-08-24 Gyanesh P. Khare Particulate compositions that comprise zinc aluminate
EA002806B1 (ru) * 1997-09-11 2002-10-31 Нюкомед Данмарк А/С Многоединичные композиции с модифицированным высвобождением нестероидных противовоспалительных лекарственных веществ (nsaid)
KR100554924B1 (ko) * 1998-05-18 2006-03-03 다케다 야쿠힌 고교 가부시키가이샤 구강내 붕괴 정제
DE19850238A1 (de) * 1998-10-31 2000-05-04 Triple Trian Beteiligungs Gmbh Verfahren und Vorrichtung zur Kompensation von Elektrosmog
US7070803B2 (en) * 2000-03-31 2006-07-04 Nycomed Austria Gmbh Controlled release pharmaceutical composition for oral use containing midodrine and/or active metabolite, desglymidodrine
US6749867B2 (en) * 2000-11-29 2004-06-15 Joseph R. Robinson Delivery system for omeprazole and its salts
SE0100200D0 (sv) * 2001-01-24 2001-01-24 Astrazeneca Ab New film coating
DE10149674A1 (de) * 2001-10-09 2003-04-24 Apogepha Arzneimittel Gmbh Orale Darreichungsformen für Propiverin oder seinen pharmazeutisch annehmbaren Salzen mit verlängerter Wirkstoffreisetzung
AU2004263130A1 (en) * 2003-08-06 2005-02-17 Nirmal Mulye Pharmaceutical composition containing water soluble drug

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3900811A1 (de) * 1989-01-13 1990-07-19 Kali Chemie Pharma Gmbh Neue arzneiform
WO1996037195A1 (de) * 1995-05-24 1996-11-28 Mepha Ag Neue pharmazeutische pelletformulierung
US20030133983A1 (en) * 1997-07-30 2003-07-17 Dr. Falk Pharma Gmbh. Pellet formulation for the treatment of the intestinal tract
DE19905906A1 (de) * 1999-02-11 2000-08-17 Basf Ag Verwendung von wasserlöslichen oder wasserdispergierbaren Polyether-haltigen Polymerisaten als Überzugsmittel, Bindemittel und/oder filmbildender Hilfsstoff in pharmazeutischen Darreichungsformen
WO2003051340A1 (en) * 2001-12-19 2003-06-26 Astrazeneca Ab New film coating

Also Published As

Publication number Publication date
RU2006118689A (ru) 2007-12-20
EP1677766A2 (de) 2006-07-12
MXPA06004700A (es) 2006-07-05
RU2372893C2 (ru) 2009-11-20
NZ547284A (en) 2009-12-24
US20080254112A1 (en) 2008-10-16
AU2004285284A1 (en) 2005-05-12
CA2543689A1 (en) 2005-05-12
EP1677766B1 (de) 2012-03-14
ATE549015T1 (de) 2012-03-15
JP2007509891A (ja) 2007-04-19
WO2005041934A2 (de) 2005-05-12
NO20062051L (no) 2006-07-25
WO2005041934A3 (de) 2005-12-01
BRPI0415557A (pt) 2006-12-26

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Legal Events

Date Code Title Description
DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE INVENTION TITLE TO READ A PROCESS FOR THE PREPARATION OF AN ACTIVE-INGREDIENT- CONTAINING FORMULATION WITH A COATING

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired