RU2368390C2 - Применение кальцитонина при остеоартрите - Google Patents
Применение кальцитонина при остеоартрите Download PDFInfo
- Publication number
- RU2368390C2 RU2368390C2 RU2006105479/14A RU2006105479A RU2368390C2 RU 2368390 C2 RU2368390 C2 RU 2368390C2 RU 2006105479/14 A RU2006105479/14 A RU 2006105479/14A RU 2006105479 A RU2006105479 A RU 2006105479A RU 2368390 C2 RU2368390 C2 RU 2368390C2
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- RU
- Russia
- Prior art keywords
- calcitonin
- cnac
- patient
- disodium salt
- osteoarthritis
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- 238000010998 test method Methods 0.000 description 1
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Classifications
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/00—Drugs for skeletal disorders
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
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- Physical Education & Sports Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Otolaryngology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US48940003P | 2003-07-23 | 2003-07-23 | |
| US60/489,400 | 2003-07-23 |
Publications (2)
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| RU2006105479A RU2006105479A (ru) | 2007-09-10 |
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| RU2006105479/14A RU2368390C2 (ru) | 2003-07-23 | 2004-07-22 | Применение кальцитонина при остеоартрите |
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| EP (2) | EP1651249B1 (enExample) |
| JP (2) | JP4716987B2 (enExample) |
| KR (1) | KR101070036B1 (enExample) |
| CN (1) | CN1856321B (enExample) |
| AU (2) | AU2004262906B2 (enExample) |
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| CA (1) | CA2532565C (enExample) |
| ES (2) | ES2436152T3 (enExample) |
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| PL (2) | PL2316473T3 (enExample) |
| PT (2) | PT2316473E (enExample) |
| RU (1) | RU2368390C2 (enExample) |
| TN (1) | TNSN06022A1 (enExample) |
| TW (1) | TWI343816B (enExample) |
| WO (1) | WO2005014031A1 (enExample) |
| ZA (1) | ZA200600373B (enExample) |
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| MXPA04005080A (es) * | 2004-05-27 | 2005-11-30 | Aspid S A De C V | Una composicion moduladora de la inflamacion articular cronica a base de colagena-polivinilpirrolidona. |
| WO2007035718A2 (en) | 2005-09-19 | 2007-03-29 | Emisphere Technologies, Inc. | Crystalline forms of the di-sodium salt of n-(5-chlorosalicyloyl)-8-aminocaprylic acid |
| GB0522566D0 (en) * | 2005-11-04 | 2005-12-14 | Novartis Ag | Organic compounds |
| US20080255048A1 (en) | 2005-11-17 | 2008-10-16 | Moise Azria | Pharmaceutical Composition |
| CN103356997A (zh) | 2006-08-31 | 2013-10-23 | 诺瓦提斯公司 | 用于口服递送的包含hgh 的药物组合物 |
| CN107050433A (zh) * | 2007-03-02 | 2017-08-18 | 诺华股份有限公司 | 降钙素的口服施用 |
| WO2009019307A2 (en) * | 2007-08-09 | 2009-02-12 | Novartis Ag | Oral calcitonin compositions and applications thereof |
| KR101344369B1 (ko) | 2007-11-02 | 2013-12-24 | 에미스페어 테크놀로지스, 인코포레이티드 | 비타민 ｂ12 결핍 치료방법 |
| JP5740689B2 (ja) * | 2008-08-18 | 2015-06-24 | エンテラ バイオ エルティーディー． | タンパク質の経口投与用の方法および組成物 |
| RU2537181C2 (ru) * | 2009-03-12 | 2014-12-27 | Нордик Байосайенс А/С | Лечение диабета и метаболического синдрома |
| US9096843B2 (en) | 2009-12-01 | 2015-08-04 | Novo Nordisk A/S | Peptidyl α-hydroxyglycine α-amidating lyases |
| US20120071410A1 (en) | 2010-09-21 | 2012-03-22 | Unigene Laboratories Inc. | Calcitonin products and therapies for treating inflammatory or degenerative diseases |
| SI3095484T1 (en) | 2011-11-02 | 2018-08-31 | Keybioscience Ag | Calcitonin mimetics for the treatment of diseases and disorders |
| KR102019911B1 (ko) | 2011-11-02 | 2019-09-09 | 키바이오사이언스 아게 | 질병 및 장애 치료용 펩타이드 유사체 |
| CN104302761A (zh) * | 2012-03-16 | 2015-01-21 | 生育创新有限公司 | 精细胞的处理 |
| HUE037663T2 (hu) | 2013-11-14 | 2018-09-28 | Keybioscience Ag | Kalcitonin mimetikumok betegségek és rendellenességek kezelésére |
| CN104095828A (zh) * | 2014-07-29 | 2014-10-15 | 中国药科大学 | 一种降钙素口服肠溶组合物及其制备方法 |
| GB201500263D0 (en) | 2015-01-08 | 2015-02-25 | Keybioscience Ag | Calcitonin analogues for treating diseases and disorders |
| US9849125B1 (en) | 2015-11-03 | 2017-12-26 | Banner Lifie Sciences LLC | Anti-overingestion dosage forms |
| GB201704429D0 (en) | 2017-03-21 | 2017-05-03 | Keybioscience Ag | Calcitonin mimetics for treating diseases and disorders |
| GB201707955D0 (en) | 2017-05-18 | 2017-07-05 | Keybioscience Ag | Dual amylin and calcitonin receptor agonists for treating diseases and disorders |
| US10335375B2 (en) | 2017-05-30 | 2019-07-02 | Patheon Softgels, Inc. | Anti-overingestion abuse deterrent compositions |
| KR20190036903A (ko) | 2017-09-28 | 2019-04-05 | (주)휴럼 | 리트세노라이드를 유효성분으로 하는 염증과 골관절염에 대한 예방 및 치료용 약학 조성물 |
| US11274158B2 (en) * | 2018-01-30 | 2022-03-15 | Flagship Pioneering Innovations V, Inc. | Methods and compositions for treating inflammatory or autoimmune diseases or conditions using calcitonin receptor activators |
| CN108586601B (zh) * | 2018-05-14 | 2021-07-27 | 四川大学 | 一种骨靶向性鲑鱼降钙素及其制备方法 |
| GB201813677D0 (en) | 2018-08-22 | 2018-10-03 | Keybioscience Ag | Calcitonin mimetics for treating diseases and disorders |
| GB201813678D0 (en) | 2018-08-22 | 2018-10-03 | Keybioscience Ag | Acylated calcitonin mimetics |
| WO2021178454A1 (en) | 2020-03-02 | 2021-09-10 | Magic Leap, Inc. | Immersive audio platform |
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| RU98118372A (ru) * | 1996-03-08 | 2000-10-20 | Фармация Энд Апджон Компани | Новые производные гидроксамовой кислоты, полезные для лечения заболеваний, связанных с дегенерацией соединительной ткани |
| WO2002045754A2 (en) * | 2000-12-06 | 2002-06-13 | Novartis Ag | Pharmaceutical compositions for the oral delivery of pharmacologically active agents |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US608618A (en) | 1898-08-09 | Thomas millen | ||
| HU203204B (en) | 1987-09-15 | 1991-06-28 | Sandoz Ag | Process for producing suppository containing calcitonin and taurocholic acid |
| JP3501471B2 (ja) * | 1992-06-15 | 2004-03-02 | 旭化成ファーマ株式会社 | カルシトニン類の安定化組成物および安定化法 |
| US5681811A (en) | 1993-05-10 | 1997-10-28 | Protein Delivery, Inc. | Conjugation-stabilized therapeutic agent compositions, delivery and diagnostic formulations comprising same, and method of making and using the same |
| US5359030A (en) | 1993-05-10 | 1994-10-25 | Protein Delivery, Inc. | Conjugation-stabilized polypeptide compositions, therapeutic delivery and diagnostic formulations comprising same, and method of making and using the same |
| US6191105B1 (en) | 1993-05-10 | 2001-02-20 | Protein Delivery, Inc. | Hydrophilic and lipophilic balanced microemulsion formulations of free-form and/or conjugation-stabilized therapeutic agents such as insulin |
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| US5912014A (en) | 1996-03-15 | 1999-06-15 | Unigene Laboratories, Inc. | Oral salmon calcitonin pharmaceutical products |
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| US5773647A (en) | 1997-02-07 | 1998-06-30 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| IL145546A0 (en) * | 1999-04-05 | 2002-06-30 | Emisphere Tech Inc | Disodium salts, monohydrates, and ethanol solvates for delivering active agents |
| US6309633B1 (en) | 1999-06-19 | 2001-10-30 | Nobex Corporation | Amphiphilic drug-oligomer conjugates with hydroyzable lipophile components and methods for making and using the same |
| US6380405B1 (en) | 1999-09-13 | 2002-04-30 | Nobex Corporation | Taxane prodrugs |
| US6436990B1 (en) | 1999-10-27 | 2002-08-20 | Nobex Corporation | 6-methoxy-2-naphthylacetic acid prodrugs |
| US20020012459A1 (en) * | 2000-06-22 | 2002-01-31 | Chips Brain Co. Ltd. | Method and apparatus for detecting stereo disparity in sequential parallel processing mode |
| JP5112595B2 (ja) | 2000-08-29 | 2013-01-09 | バイオコン・リミテッド | 抗炎症活性および抗生物質活性を有する５−ａｓａ誘導体およびこれを用いて疾患を治療する方法 |
| JP2004519428A (ja) | 2000-10-25 | 2004-07-02 | スミスクライン・ビーチャム・コーポレイション | カルシライティック化合物 |
| US6479692B1 (en) | 2001-05-02 | 2002-11-12 | Nobex Corporation | Methods of synthesizing acylanilides including bicalutamide and derivatives thereof |
| JP4959917B2 (ja) | 2001-08-17 | 2012-06-27 | ノバルティス アーゲー | 副甲状腺ホルモンフラグメント用経口送達剤としての５−ｃｎａｃ |
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2004
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- 2004-07-22 NZ NZ544645A patent/NZ544645A/xx not_active IP Right Cessation
- 2004-07-22 EP EP10177751.4A patent/EP2316473B1/en not_active Expired - Lifetime
- 2004-07-22 CN CN2004800210875A patent/CN1856321B/zh not_active Expired - Fee Related
- 2004-07-22 CA CA2532565A patent/CA2532565C/en not_active Expired - Fee Related
- 2004-07-22 ES ES10177751T patent/ES2436152T3/es not_active Expired - Lifetime
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- 2004-07-22 PL PL10177751T patent/PL2316473T3/pl unknown
- 2004-07-22 PL PL04741224T patent/PL1651249T3/pl unknown
- 2004-07-22 ES ES04741224T patent/ES2398237T3/es not_active Expired - Lifetime
- 2004-07-22 KR KR1020067001391A patent/KR101070036B1/ko not_active Expired - Fee Related
- 2004-07-22 WO PCT/EP2004/008210 patent/WO2005014031A1/en not_active Ceased
- 2004-07-22 RU RU2006105479/14A patent/RU2368390C2/ru not_active IP Right Cessation
- 2004-07-22 PT PT101777514T patent/PT2316473E/pt unknown
- 2004-07-22 PT PT47412242T patent/PT1651249E/pt unknown
- 2004-07-22 TW TW093121910A patent/TWI343816B/zh not_active IP Right Cessation
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2006
- 2006-01-05 IL IL173002A patent/IL173002A/en not_active IP Right Cessation
- 2006-01-13 ZA ZA200600373A patent/ZA200600373B/en unknown
- 2006-01-20 TN TNP2006000022A patent/TNSN06022A1/en unknown
- 2006-01-23 MA MA28746A patent/MA27929A1/fr unknown
- 2006-02-21 IS IS8316A patent/IS8316A/is unknown
- 2006-02-23 NO NO20060890A patent/NO330867B1/no not_active IP Right Cessation
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2008
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2010
- 2010-06-21 US US12/819,583 patent/US8765675B2/en not_active Expired - Fee Related
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2011
- 2011-02-22 JP JP2011035273A patent/JP2011121987A/ja active Pending
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2013
- 2013-08-15 IL IL227988A patent/IL227988A/en not_active IP Right Cessation
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2014
- 2014-06-02 US US14/293,459 patent/US20140271735A1/en not_active Abandoned
Patent Citations (2)
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| RU98118372A (ru) * | 1996-03-08 | 2000-10-20 | Фармация Энд Апджон Компани | Новые производные гидроксамовой кислоты, полезные для лечения заболеваний, связанных с дегенерацией соединительной ткани |
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