IL173002A - Use of calcitonin in the manufacture of oral medication for the prevention or treatment of osteoarthritis - Google Patents

Use of calcitonin in the manufacture of oral medication for the prevention or treatment of osteoarthritis

Info

Publication number
IL173002A
IL173002A IL173002A IL17300206A IL173002A IL 173002 A IL173002 A IL 173002A IL 173002 A IL173002 A IL 173002A IL 17300206 A IL17300206 A IL 17300206A IL 173002 A IL173002 A IL 173002A
Authority
IL
Israel
Prior art keywords
calcitonin
preventing
manufacture
treating osteoarthritis
oral medicament
Prior art date
Application number
IL173002A
Other languages
English (en)
Hebrew (he)
Other versions
IL173002A0 (en
Original Assignee
Novartis Ag
Nordic Bioscience As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34135096&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL173002(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag, Nordic Bioscience As filed Critical Novartis Ag
Publication of IL173002A0 publication Critical patent/IL173002A0/en
Publication of IL173002A publication Critical patent/IL173002A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/23Calcitonins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0031Rectum, anus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Otolaryngology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL173002A 2003-07-23 2006-01-05 Use of calcitonin in the manufacture of oral medication for the prevention or treatment of osteoarthritis IL173002A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48940003P 2003-07-23 2003-07-23
PCT/EP2004/008210 WO2005014031A1 (en) 2003-07-23 2004-07-22 Use of calcitonin in osteoarthritis

Publications (2)

Publication Number Publication Date
IL173002A0 IL173002A0 (en) 2006-06-11
IL173002A true IL173002A (en) 2013-09-30

Family

ID=34135096

Family Applications (2)

Application Number Title Priority Date Filing Date
IL173002A IL173002A (en) 2003-07-23 2006-01-05 Use of calcitonin in the manufacture of oral medication for the prevention or treatment of osteoarthritis
IL227988A IL227988A (en) 2003-07-23 2013-08-15 Pharmaceuticals containing calcitonin for use in the treatment of osteoarthritis

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL227988A IL227988A (en) 2003-07-23 2013-08-15 Pharmaceuticals containing calcitonin for use in the treatment of osteoarthritis

Country Status (22)

Country Link
US (3) US7749954B2 (enExample)
EP (2) EP1651249B1 (enExample)
JP (2) JP4716987B2 (enExample)
KR (1) KR101070036B1 (enExample)
CN (1) CN1856321B (enExample)
AU (2) AU2004262906B2 (enExample)
BR (1) BRPI0412265A (enExample)
CA (1) CA2532565C (enExample)
ES (2) ES2436152T3 (enExample)
IL (2) IL173002A (enExample)
IS (1) IS8316A (enExample)
MA (1) MA27929A1 (enExample)
MX (1) MXPA06000807A (enExample)
NO (1) NO330867B1 (enExample)
NZ (1) NZ544645A (enExample)
PL (2) PL2316473T3 (enExample)
PT (2) PT2316473E (enExample)
RU (1) RU2368390C2 (enExample)
TN (1) TNSN06022A1 (enExample)
TW (1) TWI343816B (enExample)
WO (1) WO2005014031A1 (enExample)
ZA (1) ZA200600373B (enExample)

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MXPA04005080A (es) * 2004-05-27 2005-11-30 Aspid S A De C V Una composicion moduladora de la inflamacion articular cronica a base de colagena-polivinilpirrolidona.
WO2007035718A2 (en) 2005-09-19 2007-03-29 Emisphere Technologies, Inc. Crystalline forms of the di-sodium salt of n-(5-chlorosalicyloyl)-8-aminocaprylic acid
GB0522566D0 (en) * 2005-11-04 2005-12-14 Novartis Ag Organic compounds
US20080255048A1 (en) 2005-11-17 2008-10-16 Moise Azria Pharmaceutical Composition
CN103356997A (zh) 2006-08-31 2013-10-23 诺瓦提斯公司 用于口服递送的包含hgh 的药物组合物
CN107050433A (zh) * 2007-03-02 2017-08-18 诺华股份有限公司 降钙素的口服施用
WO2009019307A2 (en) * 2007-08-09 2009-02-12 Novartis Ag Oral calcitonin compositions and applications thereof
KR101344369B1 (ko) 2007-11-02 2013-12-24 에미스페어 테크놀로지스, 인코포레이티드 비타민 b12 결핍 치료방법
JP5740689B2 (ja) * 2008-08-18 2015-06-24 エンテラ バイオ エルティーディー. タンパク質の経口投与用の方法および組成物
RU2537181C2 (ru) * 2009-03-12 2014-12-27 Нордик Байосайенс А/С Лечение диабета и метаболического синдрома
US9096843B2 (en) 2009-12-01 2015-08-04 Novo Nordisk A/S Peptidyl α-hydroxyglycine α-amidating lyases
US20120071410A1 (en) 2010-09-21 2012-03-22 Unigene Laboratories Inc. Calcitonin products and therapies for treating inflammatory or degenerative diseases
SI3095484T1 (en) 2011-11-02 2018-08-31 Keybioscience Ag Calcitonin mimetics for the treatment of diseases and disorders
KR102019911B1 (ko) 2011-11-02 2019-09-09 키바이오사이언스 아게 질병 및 장애 치료용 펩타이드 유사체
CN104302761A (zh) * 2012-03-16 2015-01-21 生育创新有限公司 精细胞的处理
HUE037663T2 (hu) 2013-11-14 2018-09-28 Keybioscience Ag Kalcitonin mimetikumok betegségek és rendellenességek kezelésére
CN104095828A (zh) * 2014-07-29 2014-10-15 中国药科大学 一种降钙素口服肠溶组合物及其制备方法
GB201500263D0 (en) 2015-01-08 2015-02-25 Keybioscience Ag Calcitonin analogues for treating diseases and disorders
US9849125B1 (en) 2015-11-03 2017-12-26 Banner Lifie Sciences LLC Anti-overingestion dosage forms
GB201704429D0 (en) 2017-03-21 2017-05-03 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders
GB201707955D0 (en) 2017-05-18 2017-07-05 Keybioscience Ag Dual amylin and calcitonin receptor agonists for treating diseases and disorders
US10335375B2 (en) 2017-05-30 2019-07-02 Patheon Softgels, Inc. Anti-overingestion abuse deterrent compositions
KR20190036903A (ko) 2017-09-28 2019-04-05 (주)휴럼 리트세노라이드를 유효성분으로 하는 염증과 골관절염에 대한 예방 및 치료용 약학 조성물
US11274158B2 (en) * 2018-01-30 2022-03-15 Flagship Pioneering Innovations V, Inc. Methods and compositions for treating inflammatory or autoimmune diseases or conditions using calcitonin receptor activators
CN108586601B (zh) * 2018-05-14 2021-07-27 四川大学 一种骨靶向性鲑鱼降钙素及其制备方法
GB201813677D0 (en) 2018-08-22 2018-10-03 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders
GB201813678D0 (en) 2018-08-22 2018-10-03 Keybioscience Ag Acylated calcitonin mimetics
WO2021178454A1 (en) 2020-03-02 2021-09-10 Magic Leap, Inc. Immersive audio platform

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US608618A (en) 1898-08-09 Thomas millen
HU203204B (en) 1987-09-15 1991-06-28 Sandoz Ag Process for producing suppository containing calcitonin and taurocholic acid
JP3501471B2 (ja) * 1992-06-15 2004-03-02 旭化成ファーマ株式会社 カルシトニン類の安定化組成物および安定化法
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GB9623205D0 (en) * 1996-11-07 1997-01-08 Eurand Int Novel pharmaceutical compositions
US5773647A (en) 1997-02-07 1998-06-30 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
IL145546A0 (en) * 1999-04-05 2002-06-30 Emisphere Tech Inc Disodium salts, monohydrates, and ethanol solvates for delivering active agents
US6309633B1 (en) 1999-06-19 2001-10-30 Nobex Corporation Amphiphilic drug-oligomer conjugates with hydroyzable lipophile components and methods for making and using the same
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US6436990B1 (en) 1999-10-27 2002-08-20 Nobex Corporation 6-methoxy-2-naphthylacetic acid prodrugs
US20020012459A1 (en) * 2000-06-22 2002-01-31 Chips Brain Co. Ltd. Method and apparatus for detecting stereo disparity in sequential parallel processing mode
JP5112595B2 (ja) 2000-08-29 2013-01-09 バイオコン・リミテッド 抗炎症活性および抗生物質活性を有する5−asa誘導体およびこれを用いて疾患を治療する方法
JP2004519428A (ja) 2000-10-25 2004-07-02 スミスクライン・ビーチャム・コーポレイション カルシライティック化合物
US7049283B2 (en) * 2000-12-06 2006-05-23 Novartis Ag Pharmaceutical compositions for the oral delivery of pharmacologically active agents
US6479692B1 (en) 2001-05-02 2002-11-12 Nobex Corporation Methods of synthesizing acylanilides including bicalutamide and derivatives thereof
JP4959917B2 (ja) 2001-08-17 2012-06-27 ノバルティス アーゲー 副甲状腺ホルモンフラグメント用経口送達剤としての5−cnac

Also Published As

Publication number Publication date
NO20060890L (no) 2006-04-24
EP2316473B1 (en) 2013-08-21
BRPI0412265A (pt) 2006-09-05
RU2006105479A (ru) 2007-09-10
PT1651249E (pt) 2012-12-21
ES2398237T3 (es) 2013-03-14
PL1651249T3 (pl) 2013-04-30
CN1856321B (zh) 2012-10-03
EP2316473A1 (en) 2011-05-04
TW200518769A (en) 2005-06-16
JP4716987B2 (ja) 2011-07-06
AU2004262906B2 (en) 2008-04-03
NO330867B1 (no) 2011-08-01
US20100278881A1 (en) 2010-11-04
CN1856321A (zh) 2006-11-01
PL2316473T3 (pl) 2014-05-30
CA2532565A1 (en) 2005-02-17
CA2532565C (en) 2012-05-08
KR20060034298A (ko) 2006-04-21
MA27929A1 (fr) 2006-06-01
JP2006528152A (ja) 2006-12-14
JP2011121987A (ja) 2011-06-23
EP1651249B1 (en) 2012-09-12
TWI343816B (en) 2011-06-21
EP1651249A1 (en) 2006-05-03
US8765675B2 (en) 2014-07-01
KR101070036B1 (ko) 2011-10-04
US20140271735A1 (en) 2014-09-18
IL227988A0 (en) 2013-09-30
US20060194722A1 (en) 2006-08-31
IL227988A (en) 2016-10-31
IS8316A (is) 2006-02-21
IL173002A0 (en) 2006-06-11
AU2008202879A1 (en) 2008-07-24
ES2436152T3 (es) 2013-12-27
US7749954B2 (en) 2010-07-06
WO2005014031A1 (en) 2005-02-17
TNSN06022A1 (en) 2007-10-03
MXPA06000807A (es) 2006-08-23
AU2008202879B2 (en) 2012-05-24
HK1089935A1 (en) 2006-12-15
ZA200600373B (en) 2007-01-31
AU2004262906A1 (en) 2005-02-17
HK1152229A1 (en) 2012-02-24
NZ544645A (en) 2009-04-30
RU2368390C2 (ru) 2009-09-27
PT2316473E (pt) 2013-09-20

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