RU2359038C2 - Устройство и способы выявления нуклеиновой кислоты в биологических образцах - Google Patents

Устройство и способы выявления нуклеиновой кислоты в биологических образцах Download PDF

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RU2359038C2
RU2359038C2 RU2006111450/13A RU2006111450A RU2359038C2 RU 2359038 C2 RU2359038 C2 RU 2359038C2 RU 2006111450/13 A RU2006111450/13 A RU 2006111450/13A RU 2006111450 A RU2006111450 A RU 2006111450A RU 2359038 C2 RU2359038 C2 RU 2359038C2
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dielectric material
layer
specified
electrode
nucleic acid
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RU2006111450/13A
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Russian (ru)
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RU2006111450A (ru
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Чэун Хой ЮЙ (CN)
Чэун Хой ЮЙ
Лок-Тин ЛАУ (CN)
Лок-Тин ЛАУ
Ка Вай ВОНГ (CN)
Ка Вай ВОНГ
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Хай Кан Лайф Корпорейшн Лимитед
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
RU2006111450/13A 2003-10-16 2004-10-18 Устройство и способы выявления нуклеиновой кислоты в биологических образцах RU2359038C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/686,252 US7390622B2 (en) 2003-10-16 2003-10-16 Apparatus and methods for detecting nucleic acid in biological samples
US10/686,252 2003-10-16

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RU2006111450A RU2006111450A (ru) 2007-10-20
RU2359038C2 true RU2359038C2 (ru) 2009-06-20

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RU2006111450/13A RU2359038C2 (ru) 2003-10-16 2004-10-18 Устройство и способы выявления нуклеиновой кислоты в биологических образцах

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US (3) US7390622B2 (enExample)
EP (2) EP1673476B1 (enExample)
JP (2) JP5248017B2 (enExample)
CN (1) CN1867681B (enExample)
AU (1) AU2004282235B2 (enExample)
BR (1) BRPI0415342A (enExample)
CA (1) CA2542518C (enExample)
MX (1) MXPA06004205A (enExample)
MY (2) MY144038A (enExample)
RU (1) RU2359038C2 (enExample)
SG (1) SG147452A1 (enExample)
TW (1) TWI360655B (enExample)
WO (1) WO2005038048A1 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2661784C2 (ru) * 2013-02-07 2018-07-19 Конинклейке Филипс Н.В. Обработка нуклеотидных последовательностей
US10330630B2 (en) 2012-06-28 2019-06-25 Siemens Healthcare Diagnostics Inc. Reader device and method of signal amplification
RU2765308C2 (ru) * 2016-02-29 2022-01-28 Айридия, Инк. Способы, композиции и устройства для хранения информации
US11505825B2 (en) 2016-02-29 2022-11-22 Iridia, Inc. Methods of synthesizing DNA
US11837302B1 (en) 2020-08-07 2023-12-05 Iridia, Inc. Systems and methods for writing and reading data stored in a polymer using nano-channels

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7390622B2 (en) * 2003-10-16 2008-06-24 Hai Kang Life Corporation Limited Apparatus and methods for detecting nucleic acid in biological samples
US8906609B1 (en) 2005-09-26 2014-12-09 Arrowhead Center, Inc. Label-free biomolecule sensor based on surface charge modulated ionic conductance
KR100723427B1 (ko) * 2006-05-12 2007-05-30 삼성전자주식회사 기판상에 생체분자 액적을 프린팅하는 장치 및 방법
US20080221805A1 (en) * 2007-03-09 2008-09-11 David Richard Andrews Multi-channel lock-in amplifier system and method
ES2307430B1 (es) * 2007-05-09 2009-10-20 Consejo Superior De Investigaciones Cientificas Biosensor y sus aplicaciones.
BRPI0813718A2 (pt) 2007-07-13 2014-12-30 Univ Leland Stanford Junior Método e aparelho que utilizam um campo elétrico para ensaios biológicos aperfeiçoados
KR100969671B1 (ko) * 2008-03-28 2010-07-14 디지탈 지노믹스(주) 고감도 바이오 센서 및 이를 포함하는 바이오 칩 그리고이를 제조하는 방법
WO2011108540A1 (ja) 2010-03-03 2011-09-09 国立大学法人大阪大学 ヌクレオチドを識別する方法および装置、ならびにポリヌクレオチドのヌクレオチド配列を決定する方法および装置
US9151759B2 (en) * 2013-05-06 2015-10-06 Research Foundation Of The City University Of New York Method for detecting cells with elastic cell membranes
CN106104274B (zh) 2013-09-18 2018-05-22 量子生物有限公司 生物分子测序装置、系统和方法
JP2015077652A (ja) 2013-10-16 2015-04-23 クオンタムバイオシステムズ株式会社 ナノギャップ電極およびその製造方法
US10438811B1 (en) 2014-04-15 2019-10-08 Quantum Biosystems Inc. Methods for forming nano-gap electrodes for use in nanosensors
WO2015170782A1 (en) 2014-05-08 2015-11-12 Osaka University Devices, systems and methods for linearization of polymers
CN106536710B (zh) 2014-08-08 2018-07-06 应用材料公司 用于生物医用器件的液膜的图案化沉积
US10379101B2 (en) * 2015-11-23 2019-08-13 Hai Kang Life Corporation Limited Apparatus for detection of biomolecules and its fabrication
CN115595360A (zh) 2016-04-27 2023-01-13 因美纳剑桥有限公司（Gb） 用于生物分子的测量和测序的系统和方法
CN108130273B (zh) * 2016-12-01 2021-10-12 京东方科技集团股份有限公司 检测基板及其制作方法、检测核酸的方法
EP3732302A4 (en) * 2017-12-28 2021-09-15 Ador Diagnostics S.r.l. METHOD FOR RAPID DETECTION OF THE PRESENCE OF TARGET MOLECULES OF NUCLEIC ACID

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2032908C1 (ru) * 1991-04-26 1995-04-10 Институт геохимии и аналитической химии им.В.И.Вернадского РАН Устройство для определения биологически активных соединений в биологических жидкостях и способ изготовления чувствительного элемента
US5605662A (en) * 1993-11-01 1997-02-25 Nanogen, Inc. Active programmable electronic devices for molecular biological analysis and diagnostics

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1337173C (en) * 1989-04-28 1995-10-03 Westaim Biomedical Corp. Thin film diagnostic device
US5632957A (en) * 1993-11-01 1997-05-27 Nanogen Molecular biological diagnostic systems including electrodes
US6017696A (en) * 1993-11-01 2000-01-25 Nanogen, Inc. Methods for electronic stringency control for molecular biological analysis and diagnostics
US6306348B1 (en) * 1993-11-01 2001-10-23 Nanogen, Inc. Inorganic permeation layer for micro-electric device
JPH08154656A (ja) * 1994-12-05 1996-06-18 Nikon Corp 核酸ハイブリダイゼーション試験の方法、核酸ハイブリダイゼーション試験用基材および核酸ハイブリダイゼーション試験用装置
US5605622A (en) * 1995-07-18 1997-02-25 Ferraro; Michael J. Swimming pool vacuum system
AU745126B2 (en) * 1997-04-16 2002-03-14 Applied Biosystems, Llc Nucleic acid archiving
US20040053290A1 (en) * 2000-01-11 2004-03-18 Terbrueggen Robert Henry Devices and methods for biochip multiplexing
US20020177135A1 (en) * 1999-07-27 2002-11-28 Doung Hau H. Devices and methods for biochip multiplexing
WO2001043870A2 (en) * 1999-12-15 2001-06-21 Motorola Inc. Column and row addressable high density biochip array
US20020090649A1 (en) * 1999-12-15 2002-07-11 Tony Chan High density column and row addressable electrode arrays
US6458000B2 (en) * 1999-12-30 2002-10-01 Thomas & Betts International, Inc. Power connector ground polarization insert and connector used therewith
AU2001252973A1 (en) * 2000-04-17 2001-10-30 Purdue Research Foundation Biosensor and related method
US7306924B2 (en) * 2000-04-17 2007-12-11 Purdue Research Foundation Biosensor and related method
WO2002031463A2 (en) * 2000-08-31 2002-04-18 Motorola, Inc. High density column and row addressable electrode arrays
JP4193345B2 (ja) * 2000-09-07 2008-12-10 横河電機株式会社 生体高分子の遺伝子配列を計測するための測定装置
EP1331999A2 (en) * 2000-11-03 2003-08-06 Clinical Micro Sensors, Inc. Devices and methods for biochip multiplexing
JP3758183B2 (ja) * 2001-11-08 2006-03-22 横河電機株式会社 バイオチップおよびそれを用いた遺伝子配列測定装置
US7153687B2 (en) * 2002-08-13 2006-12-26 Hong Kong Dna Chips Limited Apparatus and methods for detecting DNA in biological samples
CN1186627C (zh) 2003-02-28 2005-01-26 北京青鸟元芯微系统科技有限责任公司 低功耗化学气体传感器芯片及其制备方法
JP4482856B2 (ja) * 2003-08-29 2010-06-16 セイコーエプソン株式会社 試料中の標的物質の検出方法、センサ基体、及び検出キット
JP4281479B2 (ja) * 2003-09-05 2009-06-17 ソニー株式会社 電極ユニットと該電極ユニットを用いる物質間の相互作用検出のためのバイオアッセイ用基板
JP4403376B2 (ja) * 2003-10-09 2010-01-27 ソニー株式会社 物質間の相互作用検出部と該検出部を備えるバイオアッセイ用基板及び該検出部への水溶液供給方法
US7390622B2 (en) * 2003-10-16 2008-06-24 Hai Kang Life Corporation Limited Apparatus and methods for detecting nucleic acid in biological samples

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2032908C1 (ru) * 1991-04-26 1995-04-10 Институт геохимии и аналитической химии им.В.И.Вернадского РАН Устройство для определения биологически активных соединений в биологических жидкостях и способ изготовления чувствительного элемента
US5605662A (en) * 1993-11-01 1997-02-25 Nanogen, Inc. Active programmable electronic devices for molecular biological analysis and diagnostics

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
UMEK R.M. et al. "Electronic detection of nucleic acids: a versatile platform for molecular diagnostics", J Mol Diagn. 2001 May; 3 (2): 74-84. *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10330630B2 (en) 2012-06-28 2019-06-25 Siemens Healthcare Diagnostics Inc. Reader device and method of signal amplification
US10921280B2 (en) 2012-06-28 2021-02-16 Siemens Healthcare Diagnostics Inc. Reader device and method of signal amplification
RU2661784C2 (ru) * 2013-02-07 2018-07-19 Конинклейке Филипс Н.В. Обработка нуклеотидных последовательностей
RU2765308C2 (ru) * 2016-02-29 2022-01-28 Айридия, Инк. Способы, композиции и устройства для хранения информации
US11505825B2 (en) 2016-02-29 2022-11-22 Iridia, Inc. Methods of synthesizing DNA
US11549140B2 (en) 2016-02-29 2023-01-10 Iridia, Inc. Systems and methods for writing, reading, and controlling data stored in a polymer
US11837302B1 (en) 2020-08-07 2023-12-05 Iridia, Inc. Systems and methods for writing and reading data stored in a polymer using nano-channels

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Publication number Publication date
CA2542518A1 (en) 2005-04-28
JP2013140168A (ja) 2013-07-18
WO2005038048A1 (en) 2005-04-28
HK1098177A1 (en) 2007-07-13
US20050084865A1 (en) 2005-04-21
RU2006111450A (ru) 2007-10-20
BRPI0415342A (pt) 2006-12-05
TW200517656A (en) 2005-06-01
US20080242562A1 (en) 2008-10-02
SG147452A1 (en) 2008-11-28
CA2542518C (en) 2012-05-29
EP1673476A1 (en) 2006-06-28
EP1673476A4 (en) 2010-01-06
US7390622B2 (en) 2008-06-24
US7888109B2 (en) 2011-02-15
MY139466A (en) 2009-10-30
AU2004282235B2 (en) 2011-09-08
JP5248017B2 (ja) 2013-07-31
MXPA06004205A (es) 2007-02-16
AU2004282235A1 (en) 2005-04-28
TWI360655B (en) 2012-03-21
CN1867681A (zh) 2006-11-22
JP2007508554A (ja) 2007-04-05
US20120010093A1 (en) 2012-01-12
MY144038A (en) 2011-07-29
EP2554683A1 (en) 2013-02-06
CN1867681B (zh) 2010-12-08
EP1673476B1 (en) 2013-06-12

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