JP5248017B2 - 生物サンプル中の核酸を検出するための器具および方法 - Google Patents
生物サンプル中の核酸を検出するための器具および方法 Download PDFInfo
- Publication number
- JP5248017B2 JP5248017B2 JP2006534560A JP2006534560A JP5248017B2 JP 5248017 B2 JP5248017 B2 JP 5248017B2 JP 2006534560 A JP2006534560 A JP 2006534560A JP 2006534560 A JP2006534560 A JP 2006534560A JP 5248017 B2 JP5248017 B2 JP 5248017B2
- Authority
- JP
- Japan
- Prior art keywords
- layer
- dielectric material
- dielectric
- metal electrode
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/686,252 US7390622B2 (en) | 2003-10-16 | 2003-10-16 | Apparatus and methods for detecting nucleic acid in biological samples |
| US10/686,252 | 2003-10-16 | ||
| PCT/CN2004/001180 WO2005038048A1 (en) | 2003-10-16 | 2004-10-18 | Apparatus and methods for detecting nucleic acid in biological samples |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013028093A Division JP2013140168A (ja) | 2003-10-16 | 2013-02-15 | 生物サンプル中の核酸を検出するための器具および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007508554A JP2007508554A (ja) | 2007-04-05 |
| JP2007508554A5 JP2007508554A5 (enExample) | 2013-04-04 |
| JP5248017B2 true JP5248017B2 (ja) | 2013-07-31 |
Family
ID=34465492
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006534560A Expired - Lifetime JP5248017B2 (ja) | 2003-10-16 | 2004-10-18 | 生物サンプル中の核酸を検出するための器具および方法 |
| JP2013028093A Pending JP2013140168A (ja) | 2003-10-16 | 2013-02-15 | 生物サンプル中の核酸を検出するための器具および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013028093A Pending JP2013140168A (ja) | 2003-10-16 | 2013-02-15 | 生物サンプル中の核酸を検出するための器具および方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US7390622B2 (enExample) |
| EP (2) | EP1673476B1 (enExample) |
| JP (2) | JP5248017B2 (enExample) |
| CN (1) | CN1867681B (enExample) |
| AU (1) | AU2004282235B2 (enExample) |
| BR (1) | BRPI0415342A (enExample) |
| CA (1) | CA2542518C (enExample) |
| MX (1) | MXPA06004205A (enExample) |
| MY (2) | MY144038A (enExample) |
| RU (1) | RU2359038C2 (enExample) |
| SG (1) | SG147452A1 (enExample) |
| TW (1) | TWI360655B (enExample) |
| WO (1) | WO2005038048A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013140168A (ja) * | 2003-10-16 | 2013-07-18 | Hai Kang Life Corp Ltd | 生物サンプル中の核酸を検出するための器具および方法 |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8906609B1 (en) | 2005-09-26 | 2014-12-09 | Arrowhead Center, Inc. | Label-free biomolecule sensor based on surface charge modulated ionic conductance |
| KR100723427B1 (ko) * | 2006-05-12 | 2007-05-30 | 삼성전자주식회사 | 기판상에 생체분자 액적을 프린팅하는 장치 및 방법 |
| US20080221805A1 (en) * | 2007-03-09 | 2008-09-11 | David Richard Andrews | Multi-channel lock-in amplifier system and method |
| ES2307430B1 (es) * | 2007-05-09 | 2009-10-20 | Consejo Superior De Investigaciones Cientificas | Biosensor y sus aplicaciones. |
| BRPI0813718A2 (pt) | 2007-07-13 | 2014-12-30 | Univ Leland Stanford Junior | Método e aparelho que utilizam um campo elétrico para ensaios biológicos aperfeiçoados |
| KR100969671B1 (ko) * | 2008-03-28 | 2010-07-14 | 디지탈 지노믹스(주) | 고감도 바이오 센서 및 이를 포함하는 바이오 칩 그리고이를 제조하는 방법 |
| WO2011108540A1 (ja) | 2010-03-03 | 2011-09-09 | 国立大学法人大阪大学 | ヌクレオチドを識別する方法および装置、ならびにポリヌクレオチドのヌクレオチド配列を決定する方法および装置 |
| JP5781256B2 (ja) | 2012-06-28 | 2015-09-16 | シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドSiemens Healthcare Diagnostics Inc. | リーダー装置および信号増幅方法 |
| BR112015018674A2 (pt) * | 2013-02-07 | 2017-07-18 | Koninklijke Philips Nv | aparelho para o processamento de sequências de nucleotídeos, método para o processamento de sequências de nucleotídeos, e, uso do aparelho |
| US9151759B2 (en) * | 2013-05-06 | 2015-10-06 | Research Foundation Of The City University Of New York | Method for detecting cells with elastic cell membranes |
| CN106104274B (zh) | 2013-09-18 | 2018-05-22 | 量子生物有限公司 | 生物分子测序装置、系统和方法 |
| JP2015077652A (ja) | 2013-10-16 | 2015-04-23 | クオンタムバイオシステムズ株式会社 | ナノギャップ電極およびその製造方法 |
| US10438811B1 (en) | 2014-04-15 | 2019-10-08 | Quantum Biosystems Inc. | Methods for forming nano-gap electrodes for use in nanosensors |
| WO2015170782A1 (en) | 2014-05-08 | 2015-11-12 | Osaka University | Devices, systems and methods for linearization of polymers |
| CN106536710B (zh) | 2014-08-08 | 2018-07-06 | 应用材料公司 | 用于生物医用器件的液膜的图案化沉积 |
| US10379101B2 (en) * | 2015-11-23 | 2019-08-13 | Hai Kang Life Corporation Limited | Apparatus for detection of biomolecules and its fabrication |
| US10640822B2 (en) | 2016-02-29 | 2020-05-05 | Iridia, Inc. | Systems and methods for writing, reading, and controlling data stored in a polymer |
| RU2022101599A (ru) * | 2016-02-29 | 2022-02-25 | Айридия, Инк. | Способы, композиции и устройства для хранения информации |
| CN115595360A (zh) | 2016-04-27 | 2023-01-13 | 因美纳剑桥有限公司(Gb) | 用于生物分子的测量和测序的系统和方法 |
| CN108130273B (zh) * | 2016-12-01 | 2021-10-12 | 京东方科技集团股份有限公司 | 检测基板及其制作方法、检测核酸的方法 |
| EP3732302A4 (en) * | 2017-12-28 | 2021-09-15 | Ador Diagnostics S.r.l. | METHOD FOR RAPID DETECTION OF THE PRESENCE OF TARGET MOLECULES OF NUCLEIC ACID |
| US11837302B1 (en) | 2020-08-07 | 2023-12-05 | Iridia, Inc. | Systems and methods for writing and reading data stored in a polymer using nano-channels |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CA1337173C (en) * | 1989-04-28 | 1995-10-03 | Westaim Biomedical Corp. | Thin film diagnostic device |
| RU2032908C1 (ru) * | 1991-04-26 | 1995-04-10 | Институт геохимии и аналитической химии им.В.И.Вернадского РАН | Устройство для определения биологически активных соединений в биологических жидкостях и способ изготовления чувствительного элемента |
| US5632957A (en) * | 1993-11-01 | 1997-05-27 | Nanogen | Molecular biological diagnostic systems including electrodes |
| US6017696A (en) * | 1993-11-01 | 2000-01-25 | Nanogen, Inc. | Methods for electronic stringency control for molecular biological analysis and diagnostics |
| US5605662A (en) * | 1993-11-01 | 1997-02-25 | Nanogen, Inc. | Active programmable electronic devices for molecular biological analysis and diagnostics |
| US6306348B1 (en) * | 1993-11-01 | 2001-10-23 | Nanogen, Inc. | Inorganic permeation layer for micro-electric device |
| JPH08154656A (ja) * | 1994-12-05 | 1996-06-18 | Nikon Corp | 核酸ハイブリダイゼーション試験の方法、核酸ハイブリダイゼーション試験用基材および核酸ハイブリダイゼーション試験用装置 |
| US5605622A (en) * | 1995-07-18 | 1997-02-25 | Ferraro; Michael J. | Swimming pool vacuum system |
| AU745126B2 (en) * | 1997-04-16 | 2002-03-14 | Applied Biosystems, Llc | Nucleic acid archiving |
| US20040053290A1 (en) * | 2000-01-11 | 2004-03-18 | Terbrueggen Robert Henry | Devices and methods for biochip multiplexing |
| US20020177135A1 (en) * | 1999-07-27 | 2002-11-28 | Doung Hau H. | Devices and methods for biochip multiplexing |
| WO2001043870A2 (en) * | 1999-12-15 | 2001-06-21 | Motorola Inc. | Column and row addressable high density biochip array |
| US20020090649A1 (en) * | 1999-12-15 | 2002-07-11 | Tony Chan | High density column and row addressable electrode arrays |
| US6458000B2 (en) * | 1999-12-30 | 2002-10-01 | Thomas & Betts International, Inc. | Power connector ground polarization insert and connector used therewith |
| AU2001252973A1 (en) * | 2000-04-17 | 2001-10-30 | Purdue Research Foundation | Biosensor and related method |
| US7306924B2 (en) * | 2000-04-17 | 2007-12-11 | Purdue Research Foundation | Biosensor and related method |
| WO2002031463A2 (en) * | 2000-08-31 | 2002-04-18 | Motorola, Inc. | High density column and row addressable electrode arrays |
| JP4193345B2 (ja) * | 2000-09-07 | 2008-12-10 | 横河電機株式会社 | 生体高分子の遺伝子配列を計測するための測定装置 |
| EP1331999A2 (en) * | 2000-11-03 | 2003-08-06 | Clinical Micro Sensors, Inc. | Devices and methods for biochip multiplexing |
| JP3758183B2 (ja) * | 2001-11-08 | 2006-03-22 | 横河電機株式会社 | バイオチップおよびそれを用いた遺伝子配列測定装置 |
| US7153687B2 (en) * | 2002-08-13 | 2006-12-26 | Hong Kong Dna Chips Limited | Apparatus and methods for detecting DNA in biological samples |
| CN1186627C (zh) | 2003-02-28 | 2005-01-26 | 北京青鸟元芯微系统科技有限责任公司 | 低功耗化学气体传感器芯片及其制备方法 |
| JP4482856B2 (ja) * | 2003-08-29 | 2010-06-16 | セイコーエプソン株式会社 | 試料中の標的物質の検出方法、センサ基体、及び検出キット |
| JP4281479B2 (ja) * | 2003-09-05 | 2009-06-17 | ソニー株式会社 | 電極ユニットと該電極ユニットを用いる物質間の相互作用検出のためのバイオアッセイ用基板 |
| JP4403376B2 (ja) * | 2003-10-09 | 2010-01-27 | ソニー株式会社 | 物質間の相互作用検出部と該検出部を備えるバイオアッセイ用基板及び該検出部への水溶液供給方法 |
| US7390622B2 (en) * | 2003-10-16 | 2008-06-24 | Hai Kang Life Corporation Limited | Apparatus and methods for detecting nucleic acid in biological samples |
-
2003
- 2003-10-16 US US10/686,252 patent/US7390622B2/en not_active Expired - Lifetime
-
2004
- 2004-10-15 MY MYPI20083009A patent/MY144038A/en unknown
- 2004-10-15 MY MYPI20044310A patent/MY139466A/en unknown
- 2004-10-15 TW TW093131325A patent/TWI360655B/zh not_active IP Right Cessation
- 2004-10-18 SG SG200807795-0A patent/SG147452A1/en unknown
- 2004-10-18 AU AU2004282235A patent/AU2004282235B2/en not_active Ceased
- 2004-10-18 WO PCT/CN2004/001180 patent/WO2005038048A1/en not_active Ceased
- 2004-10-18 CA CA2542518A patent/CA2542518C/en not_active Expired - Fee Related
- 2004-10-18 MX MXPA06004205A patent/MXPA06004205A/es active IP Right Grant
- 2004-10-18 EP EP04789841.6A patent/EP1673476B1/en not_active Expired - Lifetime
- 2004-10-18 RU RU2006111450/13A patent/RU2359038C2/ru not_active IP Right Cessation
- 2004-10-18 EP EP12190679A patent/EP2554683A1/en not_active Withdrawn
- 2004-10-18 CN CN2004800302044A patent/CN1867681B/zh not_active Expired - Fee Related
- 2004-10-18 JP JP2006534560A patent/JP5248017B2/ja not_active Expired - Lifetime
- 2004-10-18 BR BRPI0415342-1A patent/BRPI0415342A/pt not_active IP Right Cessation
-
2008
- 2008-05-01 US US12/113,392 patent/US7888109B2/en not_active Expired - Fee Related
-
2011
- 2011-02-14 US US13/026,620 patent/US20120010093A1/en not_active Abandoned
-
2013
- 2013-02-15 JP JP2013028093A patent/JP2013140168A/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013140168A (ja) * | 2003-10-16 | 2013-07-18 | Hai Kang Life Corp Ltd | 生物サンプル中の核酸を検出するための器具および方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2542518A1 (en) | 2005-04-28 |
| JP2013140168A (ja) | 2013-07-18 |
| WO2005038048A1 (en) | 2005-04-28 |
| HK1098177A1 (en) | 2007-07-13 |
| US20050084865A1 (en) | 2005-04-21 |
| RU2006111450A (ru) | 2007-10-20 |
| BRPI0415342A (pt) | 2006-12-05 |
| TW200517656A (en) | 2005-06-01 |
| US20080242562A1 (en) | 2008-10-02 |
| SG147452A1 (en) | 2008-11-28 |
| CA2542518C (en) | 2012-05-29 |
| EP1673476A1 (en) | 2006-06-28 |
| EP1673476A4 (en) | 2010-01-06 |
| US7390622B2 (en) | 2008-06-24 |
| US7888109B2 (en) | 2011-02-15 |
| MY139466A (en) | 2009-10-30 |
| AU2004282235B2 (en) | 2011-09-08 |
| MXPA06004205A (es) | 2007-02-16 |
| AU2004282235A1 (en) | 2005-04-28 |
| TWI360655B (en) | 2012-03-21 |
| RU2359038C2 (ru) | 2009-06-20 |
| CN1867681A (zh) | 2006-11-22 |
| JP2007508554A (ja) | 2007-04-05 |
| US20120010093A1 (en) | 2012-01-12 |
| MY144038A (en) | 2011-07-29 |
| EP2554683A1 (en) | 2013-02-06 |
| CN1867681B (zh) | 2010-12-08 |
| EP1673476B1 (en) | 2013-06-12 |
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Free format text: JAPANESE INTERMEDIATE CODE: R250 |
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| EXPY | Cancellation because of completion of term |