RU2343829C2 - Сенсибилизированный оперативный bold-mri способ получения изображения - Google Patents

Сенсибилизированный оперативный bold-mri способ получения изображения Download PDF

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RU2343829C2
RU2343829C2 RU2004135823/14A RU2004135823A RU2343829C2 RU 2343829 C2 RU2343829 C2 RU 2343829C2 RU 2004135823/14 A RU2004135823/14 A RU 2004135823/14A RU 2004135823 A RU2004135823 A RU 2004135823A RU 2343829 C2 RU2343829 C2 RU 2343829C2
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bold
sensitizer
patient
mri
disease
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RU2004135823/14A
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Russian (ru)
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RU2004135823A (ru
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Йорам САЛОМОН (IL)
Йорам САЛОМОН
Михал НЕЕМАН (IL)
Михал НЕЕМАН
Авигдор ШЕРЦ (IL)
Авигдор ШЕРЦ
Шимон ГРОСС (IL)
Шимон ГРОСС
Ассаф ГИЛИД (IL)
Ассаф ГИЛИД
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Йеда Рисерч Энд Дивелопмент Ко. Лтд
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0061—5-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0076—PDT with expanded (metallo)porphyrins, i.e. having more than 20 ring atoms, e.g. texaphyrins, sapphyrins, hexaphyrins, pentaphyrins, porphocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/4806—Functional imaging of brain activation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Neurosurgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Radiation-Therapy Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
RU2004135823/14A 2002-05-08 2003-05-08 Сенсибилизированный оперативный bold-mri способ получения изображения RU2343829C2 (ru)

Applications Claiming Priority (2)

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US37840902P 2002-05-08 2002-05-08
US60/378,409 2002-05-08

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RU2004135823A RU2004135823A (ru) 2005-05-10
RU2343829C2 true RU2343829C2 (ru) 2009-01-20

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US (1) US7715901B2 (https=)
EP (2) EP1509129A4 (https=)
JP (1) JP2005524461A (https=)
AU (1) AU2003230164B2 (https=)
BR (1) BR0304716A (https=)
CA (1) CA2485224A1 (https=)
IL (1) IL164999A (https=)
NO (1) NO20040042L (https=)
RU (1) RU2343829C2 (https=)
WO (1) WO2003094695A2 (https=)

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RU2602975C2 (ru) * 2011-09-29 2016-11-20 Конинклейке Филипс Н.В. Обнаружение сигнала со сниженным искажением
RU2652071C2 (ru) * 2013-03-13 2018-04-24 Конинклейке Филипс Н.В. Устройство и способ определения насыщения кислородом крови объекта исследования

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US8315450B2 (en) * 2004-11-24 2012-11-20 Wisconsin Alumni Research Foundation Method and system for display of medical image data
KR20070112194A (ko) * 2005-02-17 2007-11-22 라이트 사이언시즈 온콜로지, 인코포레이티드 죽상동맥경화증의 예방치료를 위한 광반응성 시스템과 방법
CN101184527B (zh) * 2005-05-26 2012-05-09 皇家飞利浦电子股份有限公司 并入功能性成像信息的放射治疗方案设备
JP5139441B2 (ja) * 2006-11-30 2013-02-06 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 血管構造の可視化
JP4966640B2 (ja) * 2006-12-18 2012-07-04 学校法人慶應義塾 光線力学的治療装置およびその使用方法
CA2716940C (en) * 2008-02-29 2016-01-19 The Regents Of The University Of Michigan Systems and methods for imaging changes in tissue
WO2010043997A1 (en) * 2008-10-13 2010-04-22 Koninklijke Philips Electronics N.V. Flow insensitive magnetization preparation pulse for t2* contrast
US8571634B2 (en) * 2010-07-23 2013-10-29 David R. Hubbard Method to diagnose and measure vascular drainage insufficiency in the central nervous system
EP2425873A1 (fr) 2010-09-07 2012-03-07 Steba Maor SA Modélisation de l'action d'une fibre optique dans un traitement par therapie photodynamique, et assistance à la planification d'un tel traitement
FI20115306L (fi) 2011-03-31 2012-10-01 Valkee Oy Valon annostelulaite
US20120278380A1 (en) * 2011-04-29 2012-11-01 Joseph Curran Outdoor Tracker System with Visual Communication Devices
US9480402B2 (en) 2011-11-11 2016-11-01 Washington University System and method for task-less mapping of brain activity
US11633505B2 (en) 2012-12-11 2023-04-25 National University Corporation Kumamoto University Nuclear magnetic resonance diagnostic agent, and method for detecting or diagnosing state of cell, tissue or organ in subject using same
CN103927732B (zh) * 2013-01-11 2016-03-30 上海联影医疗科技有限公司 一种胸壁线的检测方法
US10426388B2 (en) 2014-01-31 2019-10-01 The General Hospital Corporation Prediction of tumor recurrence by measuring oxygen saturation
WO2020210813A1 (en) * 2019-04-11 2020-10-15 The General Hospital Corporation Generating imaging-based neurological state biomarkers and estimating cerebrospinal fluid (csf) dynamics based on coupled neural and csf oscillations during sleep
US11443429B2 (en) 2019-05-30 2022-09-13 Washington University Atlas registration for resting state network mapping in patients with brain tumors
CN111035612B (zh) * 2019-12-31 2020-12-18 华中科技大学 一种活性氧响应性凝胶贮库及其制备方法与应用
CN116376033B (zh) * 2023-03-03 2024-01-16 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） 一种活性氧响应的自激活骨架聚合物及其制备方法和应用
US12429544B2 (en) * 2023-03-17 2025-09-30 Texas Tech University System Method and device for detecting subclinical hypoxemia using whole blood T2P

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2602975C2 (ru) * 2011-09-29 2016-11-20 Конинклейке Филипс Н.В. Обнаружение сигнала со сниженным искажением
RU2652071C2 (ru) * 2013-03-13 2018-04-24 Конинклейке Филипс Н.В. Устройство и способ определения насыщения кислородом крови объекта исследования

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AU2003230164B2 (en) 2008-05-01
EP1509129A2 (en) 2005-03-02
BR0304716A (pt) 2004-07-13
US20060135868A1 (en) 2006-06-22
EP1509129A4 (en) 2009-03-25
EP2401962A1 (en) 2012-01-04
RU2004135823A (ru) 2005-05-10
NO20040042L (no) 2004-03-05
WO2003094695A2 (en) 2003-11-20
AU2003230164A1 (en) 2003-11-11
JP2005524461A (ja) 2005-08-18
IL164999A0 (en) 2005-12-18
IL164999A (en) 2010-12-30
CA2485224A1 (en) 2003-11-20
WO2003094695A3 (en) 2004-03-18
US7715901B2 (en) 2010-05-11

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