RU2336879C2 - Применение n-десметилклозапина для лечения нейропсихиатрических заболеваний у людей - Google Patents
Применение n-десметилклозапина для лечения нейропсихиатрических заболеваний у людей Download PDFInfo
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- RU2336879C2 RU2336879C2 RU2005126614/15A RU2005126614A RU2336879C2 RU 2336879 C2 RU2336879 C2 RU 2336879C2 RU 2005126614/15 A RU2005126614/15 A RU 2005126614/15A RU 2005126614 A RU2005126614 A RU 2005126614A RU 2336879 C2 RU2336879 C2 RU 2336879C2
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- desmethylclozapine
- ndmc
- administered
- additional therapeutic
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2506073C1 (ru) * | 2012-09-06 | 2014-02-10 | Алексей Николаевич Паршин | Способ лечения расстройства адаптации у пациентов с суицидальным риском |
| RU2667954C2 (ru) * | 2016-03-04 | 2018-09-25 | Общество С Ограниченной Ответственностью "Валентек" | Фармацевтическая композиция для лечения функциональных психических расстройств |
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| RU2002126554A (ru) | 2000-03-06 | 2004-03-20 | Акадиа Фармасьютикалз, Инк. (Us) | Азациклические соединения для применения при лечении опосредованных серотонином заболеваний |
| WO2003057698A2 (en) | 2001-12-28 | 2003-07-17 | Acadia Pharmaceuticals, Inc. | Spiroazacyclic compounds as monoamine receptor modulators |
| US7538222B2 (en) | 2002-06-24 | 2009-05-26 | Acadia Pharmaceuticals, Inc. | N-substituted piperidine derivatives as serotonin receptor agents |
| CN100509804C (zh) | 2002-06-24 | 2009-07-08 | 阿卡蒂亚药品公司 | N-取代哌啶衍生物作为血清素受体试剂 |
| US7253186B2 (en) | 2002-06-24 | 2007-08-07 | Carl-Magnus Andersson | N-substituted piperidine derivatives as serotonin receptor agents |
| PT1587789E (pt) | 2003-01-16 | 2008-12-16 | Acadia Pharm Inc | Agonistas inversos selectivos para receptores 2a/2c da serotonina como agentes terapêuticos para doenças neurodegenerativas |
| JP2006515628A (ja) * | 2003-01-23 | 2006-06-01 | アカディア ファーマシューティカルズ，インコーポレーテッド | ヒト神経精神疾患を処置するためのｎ−デスメチルクロザピンの使用 |
| US20050250767A1 (en) * | 2003-01-23 | 2005-11-10 | Weiner David M | Use of N-desmethylclozapine to treat human neuropsychiatric disease |
| US20050085463A1 (en) * | 2003-01-23 | 2005-04-21 | Weiner David M. | Use of N-desmethylclozapine to treat human neuropsychiatric disease |
| WO2004073639A2 (en) * | 2003-02-19 | 2004-09-02 | Merck & Co. Inc. | Treatment of psychosis with a muscarinic m1 receptor ectopic activator |
| US20060229292A1 (en) * | 2005-01-07 | 2006-10-12 | Astrazeneca Ab | Method of treating childhood disorders |
| KR20060082037A (ko) * | 2003-07-02 | 2006-07-14 | 아스트라제네카 아베 | 퀘티아핀의 대사산물 |
| US20060252743A1 (en) * | 2005-01-07 | 2006-11-09 | Astrazeneca Ab | Method of treating sleep disorders |
| US20070117789A1 (en) * | 2005-11-18 | 2007-05-24 | Astrazeneca Ab | Method of treatment |
| US20090093461A1 (en) * | 2003-07-02 | 2009-04-09 | Astrazeneca Ab | Methods of Treating Anxiety and Mood Disorders |
| US20060217366A1 (en) * | 2003-07-02 | 2006-09-28 | Astrazeneca Ab | Method of treating schizophrenia and other disorders |
| US20060217367A1 (en) * | 2004-07-01 | 2006-09-28 | Astrazeneca Ab | Method of treating anxiety disorders |
| US20060217365A1 (en) * | 2003-07-02 | 2006-09-28 | Astrazeneca Ab | Method of treating mood disorders |
| US20090093460A1 (en) * | 2003-07-02 | 2009-04-09 | Astrazeneca Ab | Compositions |
| US20090239840A1 (en) * | 2003-12-22 | 2009-09-24 | Acadia Pharmaceuticals, Inc. | AMINO SUBSTITUTED DIARYL[a,d]CYCLOHEPTENE ANALOGS AS MUSCARINIC AGONISTS AND METHODS OF TREATMENT OF NEUROPSYCHIATRIC DISORDERS |
| PT1696931E (pt) | 2003-12-22 | 2009-06-12 | Acadia Pharm Inc | Análogos diaril[a,d]ciclo-hepteno substituídos com amino utilizados como agonistas muscarínicos e métodos de tratamento de perturbações neuropsiquiátricas |
| US20050171088A1 (en) * | 2004-01-30 | 2005-08-04 | Astrazeneca Ab | Treatment of psychoses with dibenzothiazepine antipsychotic |
| BRPI0509524A (pt) * | 2004-04-01 | 2007-09-18 | Acadia Pharm Inc | formas cristalinas de n-desmetilclozapina |
| US20050261278A1 (en) * | 2004-05-21 | 2005-11-24 | Weiner David M | Selective serotonin receptor inverse agonists as therapeutics for disease |
| US7820695B2 (en) | 2004-05-21 | 2010-10-26 | Acadia Pharmaceuticals, Inc. | Selective serotonin receptor inverse agonists as therapeutics for disease |
| AU2005271513A1 (en) * | 2004-08-05 | 2006-02-16 | Acadia Pharmaceuticals Inc. | Use of N-desmethylclozapine to treat human neuropsychiatric disease |
| JP4996467B2 (ja) | 2004-09-27 | 2012-08-08 | アカディア ファーマシューティカルズ インコーポレイテッド | Ｎ−（４−フルオロベンジル）−ｎ−（１−メチルピペリジン−４−イル）−ｎ’−（４−（２−メチルプロピルオキシ）フェニルメチル）カルバミド、並びにその酒石酸塩及び結晶形態の合成 |
| US7790899B2 (en) | 2004-09-27 | 2010-09-07 | Acadia Pharmaceuticals, Inc. | Synthesis of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and crystalline forms |
| AU2006231497A1 (en) * | 2005-04-04 | 2006-10-12 | Acadia Pharmaceuticals Inc. | Use of N-desmethylclozapine and related compounds as dopamine stabilizing agents |
| EP2275095A3 (en) * | 2005-08-26 | 2011-08-17 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| WO2007053618A1 (en) * | 2005-10-31 | 2007-05-10 | Acadia Pharmaceuticals Inc. | Prodrugs of muscarinic agonists and methods of treatment of neuropsychiatric disorders |
| US9278947B2 (en) | 2006-06-22 | 2016-03-08 | Ramot At Tel-Aviv University Ltd. | Serotonin reuptake inhibitors as drugs having peripheral-system-restricted activity |
| EP2029566B1 (en) | 2006-06-22 | 2011-04-27 | Ramot, at Tel Aviv University Ltd. | Novel serotonin reuptake inhibitors as drugs having peripheral-system-restricted activity |
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| US9018202B2 (en) * | 2010-12-03 | 2015-04-28 | Allergan, Inc. | Methods for treating diseases of the retina |
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| WO2019046167A1 (en) | 2017-08-30 | 2019-03-07 | Acadia Pharmaceuticals Inc. | PIMAVANSERIN FORMULATIONS |
| US12459965B2 (en) | 2017-10-09 | 2025-11-04 | Compass Pathfinder Limited | Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use |
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
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| CN109761826B (zh) * | 2019-01-17 | 2022-02-25 | 烟台大学 | 一种o-去甲基文拉法辛苯醚化合物及其制备方法和用途 |
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| US3389139A (en) * | 1963-06-14 | 1968-06-18 | Wander Ag Dr A | 6-homopiperazino and piperazinomorphanthridines |
| US3908010A (en) * | 1967-03-22 | 1975-09-23 | Wander Ag Dr A | Basically substituted heterocycles as anti-emetics |
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2004
- 2004-01-21 JP JP2006501063A patent/JP2006515628A/ja not_active Withdrawn
- 2004-01-21 KR KR1020057013323A patent/KR20050092123A/ko not_active Withdrawn
- 2004-01-21 RU RU2005126614/15A patent/RU2336879C2/ru not_active IP Right Cessation
- 2004-01-21 WO PCT/US2004/001509 patent/WO2004064753A2/en not_active Ceased
- 2004-01-21 CA CA002512043A patent/CA2512043A1/en not_active Abandoned
- 2004-01-21 MX MXPA05007784A patent/MXPA05007784A/es not_active Application Discontinuation
- 2004-01-21 AU AU2004206931A patent/AU2004206931A1/en not_active Abandoned
- 2004-01-21 US US10/761,787 patent/US20040224942A1/en not_active Abandoned
- 2004-01-21 EP EP08016004A patent/EP1994932A1/en not_active Withdrawn
- 2004-01-21 EP EP04704073A patent/EP1589974A2/en not_active Ceased
- 2004-01-21 SG SG200705214-5A patent/SG159390A1/en unknown
- 2004-01-21 NZ NZ541014A patent/NZ541014A/en unknown
- 2004-01-21 CN CNA200480002642XA patent/CN1741803A/zh active Pending
- 2004-01-21 BR BR0406592-1A patent/BRPI0406592A/pt not_active IP Right Cessation
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- 2008-04-28 RU RU2008116931/14A patent/RU2008116931A/ru not_active Application Discontinuation
- 2008-09-22 US US12/235,526 patent/US20090018119A1/en not_active Abandoned
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2506073C1 (ru) * | 2012-09-06 | 2014-02-10 | Алексей Николаевич Паршин | Способ лечения расстройства адаптации у пациентов с суицидальным риском |
| RU2667954C2 (ru) * | 2016-03-04 | 2018-09-25 | Общество С Ограниченной Ответственностью "Валентек" | Фармацевтическая композиция для лечения функциональных психических расстройств |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006515628A (ja) | 2006-06-01 |
| RU2005126614A (ru) | 2006-01-27 |
| AU2004206931A1 (en) | 2004-08-05 |
| EP1589974A2 (en) | 2005-11-02 |
| MXPA05007784A (es) | 2005-09-30 |
| US20040224942A1 (en) | 2004-11-11 |
| ZA200505878B (en) | 2006-04-26 |
| WO2004064753A2 (en) | 2004-08-05 |
| CA2512043A1 (en) | 2004-08-05 |
| RU2008116931A (ru) | 2009-11-10 |
| CN1741803A (zh) | 2006-03-01 |
| NZ541014A (en) | 2008-05-30 |
| EP1994932A1 (en) | 2008-11-26 |
| SG159390A1 (en) | 2010-03-30 |
| US20090018119A1 (en) | 2009-01-15 |
| WO2004064753A3 (en) | 2004-11-25 |
| KR20050092123A (ko) | 2005-09-20 |
| BRPI0406592A (pt) | 2005-12-20 |
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