CN1741803A - N－脱甲基氯氮平在治疗人神经精神疾病中的用途 - Google Patents

N－脱甲基氯氮平在治疗人神经精神疾病中的用途 Download PDF

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Publication number
CN1741803A
CN1741803A CNA200480002642XA CN200480002642A CN1741803A CN 1741803 A CN1741803 A CN 1741803A CN A200480002642X A CNA200480002642X A CN A200480002642XA CN 200480002642 A CN200480002642 A CN 200480002642A CN 1741803 A CN1741803 A CN 1741803A
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desmethylclozapine
individual
therapeutic agent
administered
reuptake inhibitors
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Pending
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Chinese (zh)
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大卫·M·韦纳
马克·R·布兰
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Acadia Pharmaceuticals Inc
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Acadia Pharmaceuticals Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CNA200480002642XA 2003-01-23 2004-01-21 N－脱甲基氯氮平在治疗人神经精神疾病中的用途 Pending CN1741803A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44269003P 2003-01-23 2003-01-23
US60/442,690 2003-01-23

Publications (1)

Publication Number Publication Date
CN1741803A true CN1741803A (zh) 2006-03-01

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CNA200480002642XA Pending CN1741803A (zh) 2003-01-23 2004-01-21 N－脱甲基氯氮平在治疗人神经精神疾病中的用途

Country Status (14)

Country Link
US (2) US20040224942A1 (https=)
EP (2) EP1589974A2 (https=)
JP (1) JP2006515628A (https=)
KR (1) KR20050092123A (https=)
CN (1) CN1741803A (https=)
AU (1) AU2004206931A1 (https=)
BR (1) BRPI0406592A (https=)
CA (1) CA2512043A1 (https=)
MX (1) MXPA05007784A (https=)
NZ (1) NZ541014A (https=)
RU (2) RU2336879C2 (https=)
SG (1) SG159390A1 (https=)
WO (1) WO2004064753A2 (https=)
ZA (1) ZA200505878B (https=)

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US9221779B2 (en) 2006-06-22 2015-12-29 Ramot At Tel-Aviv University Ltd. Serotonin reuptake inhibitors as drugs having peripheral-system-restricted activity
US9278947B2 (en) 2006-06-22 2016-03-08 Ramot At Tel-Aviv University Ltd. Serotonin reuptake inhibitors as drugs having peripheral-system-restricted activity
WO2019085827A1 (zh) * 2017-10-30 2019-05-09 江苏理工学院 一种去甲氯氮平的新用途
CN109761826A (zh) * 2019-01-17 2019-05-17 烟台大学 一种o-去甲基文拉法辛苯醚化合物及其制备方法和用途

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CN109761826A (zh) * 2019-01-17 2019-05-17 烟台大学 一种o-去甲基文拉法辛苯醚化合物及其制备方法和用途
CN109761826B (zh) * 2019-01-17 2022-02-25 烟台大学 一种o-去甲基文拉法辛苯醚化合物及其制备方法和用途

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BRPI0406592A (pt) 2005-12-20
WO2004064753A3 (en) 2004-11-25
ZA200505878B (en) 2006-04-26
RU2005126614A (ru) 2006-01-27
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US20090018119A1 (en) 2009-01-15
SG159390A1 (en) 2010-03-30
RU2008116931A (ru) 2009-11-10
JP2006515628A (ja) 2006-06-01
EP1994932A1 (en) 2008-11-26
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KR20050092123A (ko) 2005-09-20

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