RU2218159C2 - ПРИМЕНЕНИЕ α-МЕТИЛ-п-ТИРОЗИНА ДЛЯ ИНГИБИРОВАНИЯ ПРОДУЦИРОВАНИЯ МЕЛАНИНА В МЕЛАНОЦИТАХ РАДУЖНОЙ ОБОЛОЧКИ - Google Patents

ПРИМЕНЕНИЕ α-МЕТИЛ-п-ТИРОЗИНА ДЛЯ ИНГИБИРОВАНИЯ ПРОДУЦИРОВАНИЯ МЕЛАНИНА В МЕЛАНОЦИТАХ РАДУЖНОЙ ОБОЛОЧКИ Download PDF

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RU2218159C2
RU2218159C2 RU99124771/14A RU99124771A RU2218159C2 RU 2218159 C2 RU2218159 C2 RU 2218159C2 RU 99124771/14 A RU99124771/14 A RU 99124771/14A RU 99124771 A RU99124771 A RU 99124771A RU 2218159 C2 RU2218159 C2 RU 2218159C2
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RU
Russia
Prior art keywords
melanin
tyrosine
pgf
methyl
tyrosinase
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RU99124771/14A
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English (en)
Russian (ru)
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RU99124771A (ru
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Филиппо Драго
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Фармациа Энд Апджон Аб
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU99124771/14A 1997-04-22 1998-04-21 ПРИМЕНЕНИЕ α-МЕТИЛ-п-ТИРОЗИНА ДЛЯ ИНГИБИРОВАНИЯ ПРОДУЦИРОВАНИЯ МЕЛАНИНА В МЕЛАНОЦИТАХ РАДУЖНОЙ ОБОЛОЧКИ RU2218159C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI97A000939 1997-04-22
IT97MI000939A IT1291633B1 (it) 1997-04-22 1997-04-22 Uso dell'alfa-metil-p-tirosina per inibire la produzione di melanina nei melanociti dell'iride

Publications (2)

Publication Number Publication Date
RU99124771A RU99124771A (ru) 2001-09-20
RU2218159C2 true RU2218159C2 (ru) 2003-12-10

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU99124771/14A RU2218159C2 (ru) 1997-04-22 1998-04-21 ПРИМЕНЕНИЕ α-МЕТИЛ-п-ТИРОЗИНА ДЛЯ ИНГИБИРОВАНИЯ ПРОДУЦИРОВАНИЯ МЕЛАНИНА В МЕЛАНОЦИТАХ РАДУЖНОЙ ОБОЛОЧКИ

Country Status (22)

Country Link
US (1) US6359001B1 (OSRAM)
EP (1) EP0977575B1 (OSRAM)
JP (1) JP2001521540A (OSRAM)
KR (1) KR20010020202A (OSRAM)
CN (1) CN1255064A (OSRAM)
AT (1) ATE227577T1 (OSRAM)
AU (1) AU732046B2 (OSRAM)
CA (1) CA2287887A1 (OSRAM)
DE (1) DE69809408T2 (OSRAM)
DK (1) DK0977575T3 (OSRAM)
ES (1) ES2187028T3 (OSRAM)
HU (1) HUP0002100A3 (OSRAM)
IL (1) IL132503A (OSRAM)
IT (1) IT1291633B1 (OSRAM)
NO (1) NO995122L (OSRAM)
NZ (1) NZ500435A (OSRAM)
PL (1) PL189304B1 (OSRAM)
PT (1) PT977575E (OSRAM)
RU (1) RU2218159C2 (OSRAM)
SI (1) SI0977575T1 (OSRAM)
SK (1) SK284255B6 (OSRAM)
WO (1) WO1998047515A1 (OSRAM)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL350917A1 (en) 1999-03-05 2003-02-10 Procter & Gamble C16 unsaturated fp-selective prostaglandins analogs
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
WO2010087983A1 (en) * 2009-01-29 2010-08-05 Kambiz Thomas Moazed Method and system for effecting changes in pigmented tissue
US9744237B2 (en) * 2009-01-29 2017-08-29 Kambiz Thomas Moazed Method and system for effecting changes in pigmented tissue
WO2011011065A1 (en) * 2009-07-22 2011-01-27 Kambiz Thomas Moazed Method and system for effecting changes in pigmented tissue
US8481498B1 (en) 2012-01-17 2013-07-09 Steven Hoffman Pharmaceutical compositions and methods
US20130183263A1 (en) 2012-01-17 2013-07-18 Steven Hoffman Pharmaceutical compositions and methods
US10272068B2 (en) 2012-01-17 2019-04-30 Tyme, Inc. Pharmaceutical compositions and methods
PL2804599T3 (pl) 2012-01-17 2019-06-28 Tyme, Inc. Terapia skojarzona do leczenia nowotworu złośliwego
US10646552B2 (en) 2012-01-17 2020-05-12 Tyme, Inc. Pharmaceutical compositions and methods
US9585841B2 (en) 2013-10-22 2017-03-07 Tyme, Inc. Tyrosine derivatives and compositions comprising them
US9326962B2 (en) 2013-10-22 2016-05-03 Steven Hoffman Compositions and methods for treating intestinal hyperpermeability
US9763903B2 (en) 2013-10-22 2017-09-19 Steven Hoffman Compositions and methods for treating intestinal hyperpermeability
US10751313B2 (en) 2013-10-22 2020-08-25 Yamo Pharmaceuticals Llc Compositions and methods for treating autism
US10813901B2 (en) 2013-10-22 2020-10-27 Yamo Pharmaceuticals Llc Compositions and methods for treating autism
ES2738248B2 (es) * 2018-06-21 2023-03-10 Consejo Superior Investigacion Uso de inhibidores de la tirosina hidroxilasa para el tratamiento del aneurisma de aorta
US12150924B2 (en) 2018-07-19 2024-11-26 Yamo Pharmaceuticals Llc Compositions and methods for treating autism
BR112021022784A2 (pt) 2019-05-14 2022-03-22 Tyme Inc Composições e métodos para tratamento do câncer
CN116035151A (zh) * 2023-01-18 2023-05-02 云南贝泰妮生物科技集团股份有限公司 一种刺梨闪释粉及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04117313A (ja) * 1990-09-06 1992-04-17 Kanebo Ltd 美白化粧料

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
РЛС. Энциклопедия лекарств. - М., 2000, с.468. *

Also Published As

Publication number Publication date
PL336386A1 (en) 2000-06-19
NZ500435A (en) 2001-09-28
EP0977575A1 (en) 2000-02-09
ES2187028T3 (es) 2003-05-16
ITMI970939A1 (it) 1998-10-22
AU732046B2 (en) 2001-04-12
PL189304B1 (pl) 2005-07-29
CN1255064A (zh) 2000-05-31
AU7646298A (en) 1998-11-13
HUP0002100A3 (en) 2003-05-28
SK142499A3 (en) 2000-09-12
SK284255B6 (sk) 2004-12-01
IL132503A (en) 2004-06-20
EP0977575B1 (en) 2002-11-13
DE69809408T2 (de) 2003-07-10
JP2001521540A (ja) 2001-11-06
DE69809408D1 (de) 2002-12-19
WO1998047515A1 (en) 1998-10-29
IL132503A0 (en) 2001-03-19
SI0977575T1 (en) 2003-04-30
PT977575E (pt) 2003-03-31
ATE227577T1 (de) 2002-11-15
DK0977575T3 (da) 2003-03-10
ITMI970939A0 (OSRAM) 1997-04-22
NO995122D0 (no) 1999-10-21
KR20010020202A (ko) 2001-03-15
HUP0002100A2 (hu) 2000-11-28
NO995122L (no) 1999-12-21
IT1291633B1 (it) 1999-01-11
CA2287887A1 (en) 1998-10-29
US6359001B1 (en) 2002-03-19

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20060422