PL2804599T3 - Terapia skojarzona do leczenia nowotworu złośliwego - Google Patents

Terapia skojarzona do leczenia nowotworu złośliwego

Info

Publication number
PL2804599T3
PL2804599T3 PL13738179T PL13738179T PL2804599T3 PL 2804599 T3 PL2804599 T3 PL 2804599T3 PL 13738179 T PL13738179 T PL 13738179T PL 13738179 T PL13738179 T PL 13738179T PL 2804599 T3 PL2804599 T3 PL 2804599T3
Authority
PL
Poland
Prior art keywords
cancer
treatment
combination therapy
therapy
combination
Prior art date
Application number
PL13738179T
Other languages
English (en)
Inventor
Steven Hoffman
Original Assignee
Tyme, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/371,076 external-priority patent/US8481498B1/en
Application filed by Tyme, Inc. filed Critical Tyme, Inc.
Publication of PL2804599T3 publication Critical patent/PL2804599T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/31Somatostatins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37Coumarins, e.g. psoralen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41661,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/33Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • A61K38/34Melanocyte stimulating hormone [MSH], e.g. alpha- or beta-melanotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PL13738179T 2012-01-17 2013-01-16 Terapia skojarzona do leczenia nowotworu złośliwego PL2804599T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261587420P 2012-01-17 2012-01-17
US13/371,076 US8481498B1 (en) 2012-01-17 2012-02-10 Pharmaceutical compositions and methods
US201261702994P 2012-09-19 2012-09-19
EP13738179.4A EP2804599B1 (en) 2012-01-17 2013-01-16 Combination therapy for the treatment of cancer
PCT/US2013/021714 WO2013109610A1 (en) 2012-01-17 2013-01-16 Pharmaceutical compositions and methods

Publications (1)

Publication Number Publication Date
PL2804599T3 true PL2804599T3 (pl) 2019-06-28

Family

ID=48799616

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13738179T PL2804599T3 (pl) 2012-01-17 2013-01-16 Terapia skojarzona do leczenia nowotworu złośliwego

Country Status (25)

Country Link
EP (2) EP2804599B1 (pl)
JP (4) JP6276707B2 (pl)
KR (1) KR102172658B1 (pl)
CN (2) CN104220057B (pl)
AU (4) AU2013209862A1 (pl)
BR (1) BR112014017613A2 (pl)
CA (1) CA2862689C (pl)
CY (1) CY1121450T1 (pl)
DK (1) DK2804599T3 (pl)
ES (1) ES2706070T3 (pl)
HR (1) HRP20190046T1 (pl)
HU (1) HUE045314T2 (pl)
IL (2) IL233681B (pl)
IN (1) IN2014DN06711A (pl)
LT (1) LT2804599T (pl)
MX (1) MX363579B (pl)
NZ (2) NZ721280A (pl)
PH (1) PH12014501639B1 (pl)
PL (1) PL2804599T3 (pl)
PT (1) PT2804599T (pl)
RS (1) RS58538B1 (pl)
SI (1) SI2804599T1 (pl)
SM (1) SMT201900024T1 (pl)
WO (1) WO2013109610A1 (pl)
ZA (1) ZA201405611B (pl)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10272068B2 (en) 2012-01-17 2019-04-30 Tyme, Inc. Pharmaceutical compositions and methods
US20130183263A1 (en) 2012-01-17 2013-07-18 Steven Hoffman Pharmaceutical compositions and methods
NZ721280A (en) * 2012-01-17 2017-08-25 Tyme Inc Pharmaceutical compositions and methods for treating cancer
US10646552B2 (en) 2012-01-17 2020-05-12 Tyme, Inc. Pharmaceutical compositions and methods
US9724657B2 (en) 2013-10-22 2017-08-08 Tyme, Inc. High-speed centrifugal mixing devices and methods of use
US9585841B2 (en) * 2013-10-22 2017-03-07 Tyme, Inc. Tyrosine derivatives and compositions comprising them
CN107405298A (zh) * 2014-12-23 2017-11-28 史蒂文·霍夫曼 经皮制剂
US9687528B2 (en) 2014-12-23 2017-06-27 Steven Hoffman Transdermal formulations
AU2017232348A1 (en) * 2016-03-15 2018-09-06 Tyme, Inc. Pharmaceutical compositions for the treatment of cancer
BR112018073627A2 (pt) * 2016-05-18 2019-02-26 Tyme, Inc. método para tratar câncer em um paciente
EA201991192A1 (ru) * 2016-11-15 2019-10-31 Фармацевтические композиции и способы лечения рака
CN110062633A (zh) * 2016-11-30 2019-07-26 迪美公司 酪氨酸衍生物以及包含所述酪氨酸衍生物的组合物
US11351136B2 (en) * 2017-04-21 2022-06-07 Yamo Pharmaceuticals Llc Compositions and methods for treating retinopathy
JP2022532210A (ja) 2019-05-14 2022-07-13 タイム,インコーポレーテッド がんを処置する組成物および方法
KR20220098144A (ko) * 2019-10-15 2022-07-11 타임, 인크. 암을 치료하는 데에 사용하기 위한 알파-메틸-dl-티로신의 알킬에스테르
AU2021207666A1 (en) * 2020-01-17 2022-09-01 Tyme, Inc. Tyrosine derivatives for modulating cancer
US10905698B1 (en) 2020-05-14 2021-02-02 Tyme, Inc. Methods of treating SARS-COV-2 infections
EP4255920A4 (en) * 2020-12-02 2024-10-23 Hoffman Technologies LLC COMPOSITIONS AND METHODS FOR MODULATING CANCER IN NON-HUMAN MAMMALS

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5073541A (en) * 1987-11-18 1991-12-17 Administrators Of The Tulane Educational Fund Treatment of small cell lung cancer with somatostatin analogs
DE3823735A1 (de) * 1988-07-13 1989-03-02 Ernst Hajek Verwendung von d-leucin (rechtsdrehende (alpha)-amino-isocapronsaeure) als wirkstoff zur bekaempfung maligner tumoren des schleimhautepithels des gesamten intestinaltraktes einschliesslich pankreas und gallenblase
US5225435A (en) 1990-05-18 1993-07-06 Yale University Soluble melanin
IT1291633B1 (it) * 1997-04-22 1999-01-11 Pharmaconsult S A S Uso dell'alfa-metil-p-tirosina per inibire la produzione di melanina nei melanociti dell'iride
CA2321026A1 (en) * 1998-03-09 1999-09-16 Zealand Pharmaceuticals A/S Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
EP1119252A4 (en) * 1998-08-21 2004-03-03 Childrens Medical Center USE OF MELANIN FOR INHIBITING ANGIOGENESIS AND MACULAR DEGENERATION
JP2002128304A (ja) 2000-10-20 2002-05-09 Nec Eng Ltd 給紙装置
WO2004058243A1 (ja) * 2002-12-26 2004-07-15 Ajinomoto Co., Inc. 肝癌発生・進展抑制剤
ATE431140T1 (de) * 2005-03-11 2009-05-15 Gpc Biotech Ag Antiproliferative kombinations-therapie mit satraplatin oder jm118 und docetaxel
US20080085874A1 (en) * 2006-08-28 2008-04-10 The Regents Of The University Of California Small molecule potentiator of hormonal therapy for breast cancer
JP5073541B2 (ja) 2007-05-09 2012-11-14 ルネサスエレクトロニクス株式会社 半導体記憶装置
JP2011505335A (ja) * 2007-09-11 2011-02-24 モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト 治療剤としてのTRP−6−トリプトレリンおよびD−Leu6−ロイプロリドの使用
US8110578B2 (en) * 2008-10-27 2012-02-07 Signal Pharmaceuticals, Llc Pyrazino[2,3-b]pyrazine mTOR kinase inhibitors for oncology indications and diseases associated with the mTOR/PI3K/Akt pathway
AU2011241175A1 (en) * 2010-04-16 2012-11-29 Davos Life Science Pte. Ltd. Synergistic interaction of at least one Vitamin E component and tyrosinase inhibitors for dermatological applications
NZ721280A (en) * 2012-01-17 2017-08-25 Tyme Inc Pharmaceutical compositions and methods for treating cancer

Also Published As

Publication number Publication date
CN107714684A (zh) 2018-02-23
MX2014008640A (es) 2015-03-09
CA2862689C (en) 2020-03-10
NZ628757A (en) 2016-07-29
JP2020172521A (ja) 2020-10-22
ZA201405611B (en) 2015-06-24
AU2022202113A1 (en) 2022-04-14
CN104220057A (zh) 2014-12-17
CA2862689A1 (en) 2013-07-25
EP2804599B1 (en) 2018-10-17
IL252566A0 (en) 2017-07-31
JP2022095894A (ja) 2022-06-28
NZ721280A (en) 2017-08-25
DK2804599T3 (en) 2019-02-04
JP7095028B2 (ja) 2022-07-04
EP3488848A1 (en) 2019-05-29
IL233681B (en) 2019-07-31
WO2013109610A1 (en) 2013-07-25
AU2018203026A1 (en) 2018-05-17
PH12014501639B1 (en) 2023-02-22
SI2804599T1 (sl) 2019-05-31
MX363579B (es) 2019-03-27
IL233681A0 (en) 2014-09-30
EP2804599A4 (en) 2015-10-21
KR102172658B1 (ko) 2020-11-02
ES2706070T3 (es) 2019-03-27
CN104220057B (zh) 2017-11-03
EP2804599A1 (en) 2014-11-26
JP6276707B2 (ja) 2018-02-07
IN2014DN06711A (pl) 2015-05-22
LT2804599T (lt) 2019-04-10
RS58538B1 (sr) 2019-04-30
IL252566B (en) 2020-07-30
AU2013209862A1 (en) 2014-09-04
PT2804599T (pt) 2019-01-28
BR112014017613A2 (pt) 2017-07-04
PH12014501639A1 (en) 2014-10-13
SMT201900024T1 (it) 2019-05-10
KR20140135704A (ko) 2014-11-26
HRP20190046T1 (hr) 2019-05-03
JP2015509101A (ja) 2015-03-26
JP6789916B2 (ja) 2020-11-25
HUE045314T2 (hu) 2019-12-30
AU2020201683A1 (en) 2020-03-26
JP2018065848A (ja) 2018-04-26
CY1121450T1 (el) 2020-05-29

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