DE69809408D1 - Anwendung von alpha-methyl-p-tyrosine zur hemmung der melanin-produktion in irismelanozyten - Google Patents

Anwendung von alpha-methyl-p-tyrosine zur hemmung der melanin-produktion in irismelanozyten

Info

Publication number
DE69809408D1
DE69809408D1 DE69809408T DE69809408T DE69809408D1 DE 69809408 D1 DE69809408 D1 DE 69809408D1 DE 69809408 T DE69809408 T DE 69809408T DE 69809408 T DE69809408 T DE 69809408T DE 69809408 D1 DE69809408 D1 DE 69809408D1
Authority
DE
Germany
Prior art keywords
irismelanocytes
tyrosine
inhibiting
alpha
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69809408T
Other languages
English (en)
Other versions
DE69809408T2 (de
Inventor
Filippo Drago
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Health AB
Original Assignee
Pharmacia and Upjohn AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn AB filed Critical Pharmacia and Upjohn AB
Publication of DE69809408D1 publication Critical patent/DE69809408D1/de
Application granted granted Critical
Publication of DE69809408T2 publication Critical patent/DE69809408T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69809408T 1997-04-22 1998-04-21 Anwendung von alpha-methyl-p-tyrosine zur hemmung der melanin-produktion in irismelanozyten Expired - Fee Related DE69809408T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT97MI000939A IT1291633B1 (it) 1997-04-22 1997-04-22 Uso dell'alfa-metil-p-tirosina per inibire la produzione di melanina nei melanociti dell'iride
PCT/EP1998/002365 WO1998047515A1 (en) 1997-04-22 1998-04-21 THE USE OF α-METHYL-P-TYROSINE TO INHIBIT MELANIN PRODUCTION IN IRIS MELANOCYTES

Publications (2)

Publication Number Publication Date
DE69809408D1 true DE69809408D1 (de) 2002-12-19
DE69809408T2 DE69809408T2 (de) 2003-07-10

Family

ID=11376994

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69809408T Expired - Fee Related DE69809408T2 (de) 1997-04-22 1998-04-21 Anwendung von alpha-methyl-p-tyrosine zur hemmung der melanin-produktion in irismelanozyten

Country Status (22)

Country Link
US (1) US6359001B1 (de)
EP (1) EP0977575B1 (de)
JP (1) JP2001521540A (de)
KR (1) KR20010020202A (de)
CN (1) CN1255064A (de)
AT (1) ATE227577T1 (de)
AU (1) AU732046B2 (de)
CA (1) CA2287887A1 (de)
DE (1) DE69809408T2 (de)
DK (1) DK0977575T3 (de)
ES (1) ES2187028T3 (de)
HU (1) HUP0002100A3 (de)
IL (1) IL132503A (de)
IT (1) IT1291633B1 (de)
NO (1) NO995122L (de)
NZ (1) NZ500435A (de)
PL (1) PL189304B1 (de)
PT (1) PT977575E (de)
RU (1) RU2218159C2 (de)
SI (1) SI0977575T1 (de)
SK (1) SK284255B6 (de)
WO (1) WO1998047515A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1159266B1 (de) 1999-03-05 2004-11-03 Duke University C-16 ungesätigte fp-selektive prostaglandin analoge
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
WO2011011065A1 (en) * 2009-07-22 2011-01-27 Kambiz Thomas Moazed Method and system for effecting changes in pigmented tissue
US9744237B2 (en) * 2009-01-29 2017-08-29 Kambiz Thomas Moazed Method and system for effecting changes in pigmented tissue
US20110280909A1 (en) * 2009-01-29 2011-11-17 Kambiz Thomas Moazed Method and system for effecting changes in pigmented tissue
US20130183263A1 (en) 2012-01-17 2013-07-18 Steven Hoffman Pharmaceutical compositions and methods
CA2862689C (en) * 2012-01-17 2020-03-10 Tyme, Inc. .alpha.-methyl-dl-tyrosine, compositions, kits, combinations and use thereof for the treatment of cancer or for reducing cell proliferation
US10272068B2 (en) 2012-01-17 2019-04-30 Tyme, Inc. Pharmaceutical compositions and methods
US10646552B2 (en) 2012-01-17 2020-05-12 Tyme, Inc. Pharmaceutical compositions and methods
US8481498B1 (en) 2012-01-17 2013-07-09 Steven Hoffman Pharmaceutical compositions and methods
US10813901B2 (en) 2013-10-22 2020-10-27 Yamo Pharmaceuticals Llc Compositions and methods for treating autism
US9763903B2 (en) 2013-10-22 2017-09-19 Steven Hoffman Compositions and methods for treating intestinal hyperpermeability
US9326962B2 (en) 2013-10-22 2016-05-03 Steven Hoffman Compositions and methods for treating intestinal hyperpermeability
US10751313B2 (en) 2013-10-22 2020-08-25 Yamo Pharmaceuticals Llc Compositions and methods for treating autism
US9585841B2 (en) 2013-10-22 2017-03-07 Tyme, Inc. Tyrosine derivatives and compositions comprising them
ES2738248B2 (es) * 2018-06-21 2023-03-10 Consejo Superior Investigacion Uso de inhibidores de la tirosina hidroxilasa para el tratamiento del aneurisma de aorta
MX2021013901A (es) 2019-05-14 2022-04-12 Tyme Inc Composiciones y métodos para el tratamiento del cáncer.
CN116035151A (zh) * 2023-01-18 2023-05-02 云南贝泰妮生物科技集团股份有限公司 一种刺梨闪释粉及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04117313A (ja) * 1990-09-06 1992-04-17 Kanebo Ltd 美白化粧料

Also Published As

Publication number Publication date
ITMI970939A1 (it) 1998-10-22
RU2218159C2 (ru) 2003-12-10
EP0977575B1 (de) 2002-11-13
WO1998047515A1 (en) 1998-10-29
AU732046B2 (en) 2001-04-12
CA2287887A1 (en) 1998-10-29
CN1255064A (zh) 2000-05-31
EP0977575A1 (de) 2000-02-09
HUP0002100A2 (hu) 2000-11-28
ES2187028T3 (es) 2003-05-16
ATE227577T1 (de) 2002-11-15
NO995122L (no) 1999-12-21
NZ500435A (en) 2001-09-28
HUP0002100A3 (en) 2003-05-28
SK284255B6 (sk) 2004-12-01
PL189304B1 (pl) 2005-07-29
US6359001B1 (en) 2002-03-19
IL132503A (en) 2004-06-20
JP2001521540A (ja) 2001-11-06
DE69809408T2 (de) 2003-07-10
KR20010020202A (ko) 2001-03-15
DK0977575T3 (da) 2003-03-10
PT977575E (pt) 2003-03-31
AU7646298A (en) 1998-11-13
SK142499A3 (en) 2000-09-12
IL132503A0 (en) 2001-03-19
ITMI970939A0 (de) 1997-04-22
IT1291633B1 (it) 1999-01-11
NO995122D0 (no) 1999-10-21
PL336386A1 (en) 2000-06-19
SI0977575T1 (en) 2003-04-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee