RU2206329C2 - Иммуностимулятор, вызывающий специфичный к опухоли клеточный иммунный ответ и способ его получения - Google Patents
Иммуностимулятор, вызывающий специфичный к опухоли клеточный иммунный ответ и способ его получения Download PDFInfo
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- RU2206329C2 RU2206329C2 RU98111622/14A RU98111622A RU2206329C2 RU 2206329 C2 RU2206329 C2 RU 2206329C2 RU 98111622/14 A RU98111622/14 A RU 98111622/14A RU 98111622 A RU98111622 A RU 98111622A RU 2206329 C2 RU2206329 C2 RU 2206329C2
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
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- C—CHEMISTRY; METALLURGY
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
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- A—HUMAN NECESSITIES
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- A61K39/12—Viral antigens
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- A61K39/145—Orthomyxoviridae, e.g. influenza virus
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- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
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- A—HUMAN NECESSITIES
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
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- A—HUMAN NECESSITIES
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
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- A—HUMAN NECESSITIES
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
- A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Biotechnology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- General Engineering & Computer Science (AREA)
- Developmental Biology & Embryology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19543649A DE19543649C2 (de) | 1995-11-23 | 1995-11-23 | Tumorvakzine und Verfahren zu ihrer Herstellung |
| DE19543649.0 | 1995-11-23 | ||
| DE19607044A DE19607044A1 (de) | 1996-02-24 | 1996-02-24 | Tumorvakzine und Verfahren zu ihrer Herstellung |
| DE19607044.9 | 1996-11-25 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU98111622A RU98111622A (ru) | 2000-05-20 |
| RU2206329C2 true RU2206329C2 (ru) | 2003-06-20 |
Family
ID=26020603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU98111622/14A RU2206329C2 (ru) | 1995-11-23 | 1996-11-21 | Иммуностимулятор, вызывающий специфичный к опухоли клеточный иммунный ответ и способ его получения |
Country Status (24)
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2267326C2 (ru) * | 2004-03-16 | 2006-01-10 | ГУН НИИ онкологии им. проф. Н.Н. Петрова Минздрава РФ | Способ иммунотерапии опухолевым лизатом с адъювантом беталейкин больных солидными опухолями |
| RU2404806C2 (ru) * | 2005-02-23 | 2010-11-27 | Дженентек, Инк. | Продление времени до прогрессирования заболевания или продолжительности жизни у онкологических больных с применением ингибиторов димеризации her |
| RU2556128C2 (ru) * | 2003-08-25 | 2015-07-10 | ЮниВэкс, ЭлЭлСи | Профилактическая противораковая вакцина |
| US11504421B2 (en) | 2017-05-08 | 2022-11-22 | Gritstone Bio, Inc. | Alphavirus neoantigen vectors |
| US11591619B2 (en) | 2019-05-30 | 2023-02-28 | Gritstone Bio, Inc. | Modified adenoviruses |
| RU2803566C2 (ru) * | 2017-05-08 | 2023-09-15 | Гритстоун Био, Инк. | Неоантигенные векторы на основе альфавируса |
| US11771747B2 (en) | 2020-08-06 | 2023-10-03 | Gritstone Bio, Inc. | Multiepitope vaccine cassettes |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CO4600681A1 (es) † | 1996-02-24 | 1998-05-08 | Boehringer Ingelheim Pharma | Composicion farmaceutica para la modulacion inmunitaria |
| DE69839273T2 (de) | 1997-01-31 | 2009-03-05 | Edward P. Chicago Cohen | Krebsimmuntherapie mit semi-allogenen zellen |
| ATE284707T1 (de) * | 1997-08-22 | 2005-01-15 | Science Park Raf S P A | Tumorvakzinierung mittels verwendung autologer oder hla-verwandter antigen präsentierender zellen (apc), die mit einem tumorantigen sowie einem eine immunantwort hervorrufenden fremdantigen transduziert sind |
| CA2322660A1 (en) * | 1998-03-20 | 1999-09-23 | Genzyme Corporation | Enhanced anti-tumor immunity |
| US7014848B1 (en) | 1998-03-20 | 2006-03-21 | Genzyme Corporation | Enhanced anti-tumor immunity |
| FR2807661A1 (fr) * | 2000-04-14 | 2001-10-19 | Univ Nantes | Agent et procede pour la simulation de lymphocytes t specifiques et lymphocytes t obtenus |
| EP2192407A3 (en) * | 2001-09-18 | 2011-04-27 | Green Peptide Co., Ltd. | Method of detecting cellular immunity and application thereof to drugs |
| RU2203683C1 (ru) * | 2001-09-20 | 2003-05-10 | НИИ онкологии им. проф. Н.Н. Петрова | Способ иммунотерапии костно-мозговыми дендритными клетками больных солидными опухолями |
| GB0209896D0 (en) | 2002-04-30 | 2002-06-05 | Molmed Spa | Conjugate |
| CN1315536C (zh) * | 2002-09-13 | 2007-05-16 | 李进 | 肿瘤抗原疫苗及其制备方法和疫苗组合物 |
| GB0224442D0 (en) | 2002-10-21 | 2002-11-27 | Molmed Spa | A delivery system |
| US7674456B2 (en) * | 2004-06-14 | 2010-03-09 | Charles Wiseman | Breast cancer cell lines and uses thereof |
| EP1871166A4 (en) | 2005-03-29 | 2008-11-12 | Univ Illinois | CARCINOMAS AND THERAPEUTIC PROCEDURES |
| SI1806359T1 (sl) * | 2005-09-05 | 2010-06-30 | Immatics Biotechnologies Gmbh | S tumorjem povezani peptidi ki se vežejo brez izjeme na molekule humanega levkocitnega antigena HLA razred II |
| US20090004213A1 (en) | 2007-03-26 | 2009-01-01 | Immatics Biotechnologies Gmbh | Combination therapy using active immunotherapy |
| US8765148B2 (en) | 2010-02-19 | 2014-07-01 | Valneva Austria Gmbh | 1C31 nanoparticles |
| MX364370B (es) * | 2012-07-12 | 2019-04-24 | Persimmune Inc | Vacunas contra el cancer personalizadas y terapias de celulas inmunes adoptivas. |
| JP6710004B2 (ja) | 2016-03-15 | 2020-06-17 | Ｒｅｐｅｒｔｏｉｒｅ Ｇｅｎｅｓｉｓ株式会社 | 免疫療法のためのモニタリングまたは診断ならびに治療剤の設計 |
| WO2022192701A1 (en) * | 2021-03-12 | 2022-09-15 | T-Cure Bioscience, Inc. | Methods of enhancing diversity of hla haplotype expression in tumors to broaden tumor cell susceptibility to tcr-t therapy |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0569678A2 (en) * | 1992-03-13 | 1993-11-18 | Yeda Research And Development Co. Ltd. | Double transfectants of MHC genes as cellular vaccines for immunoprevention of tumor metastasis |
| EP0563627A3 (cg-RX-API-DMAC7.html) * | 1992-03-05 | 1994-04-27 | Bio Defence Inst Co Ltd |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6235525B1 (en) * | 1991-05-23 | 2001-05-22 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules coding for tumor rejection antigen precursor MAGE-3 and uses thereof |
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1996
- 1996-11-19 UY UY24367A patent/UY24367A1/es not_active IP Right Cessation
- 1996-11-21 CZ CZ981589A patent/CZ158998A3/cs unknown
- 1996-11-21 CN CN96198493A patent/CN1202931A/zh active Pending
- 1996-11-21 RO RO98-00985A patent/RO115275B1/ro unknown
- 1996-11-21 AU AU76947/96A patent/AU720131B2/en not_active Ceased
- 1996-11-21 JP JP9519395A patent/JP2000502052A/ja not_active Abandoned
- 1996-11-21 TR TR1998/00912T patent/TR199800912T2/xx unknown
- 1996-11-21 PL PL96326756A patent/PL188537B1/pl not_active IP Right Cessation
- 1996-11-21 BR BR9611466A patent/BR9611466A/pt not_active Application Discontinuation
- 1996-11-21 KR KR1019980703681A patent/KR19990067653A/ko not_active Ceased
- 1996-11-21 EP EP96939870A patent/EP0866851A1/de not_active Withdrawn
- 1996-11-21 SK SK669-98A patent/SK66998A3/sk unknown
- 1996-11-21 EE EE9800161A patent/EE03778B1/xx not_active IP Right Cessation
- 1996-11-21 RU RU98111622/14A patent/RU2206329C2/ru not_active IP Right Cessation
- 1996-11-21 CA CA002238176A patent/CA2238176A1/en not_active Abandoned
- 1996-11-21 NZ NZ322910A patent/NZ322910A/xx unknown
- 1996-11-21 US US09/077,214 patent/US20020085997A1/en not_active Abandoned
- 1996-11-21 WO PCT/EP1996/005126 patent/WO1997019169A1/de not_active Ceased
- 1996-11-21 HU HU0000318A patent/HUP0000318A3/hu unknown
- 1996-11-22 CO CO96061701A patent/CO4520254A1/es unknown
- 1996-11-22 AR ARP960105291A patent/AR004341A1/es not_active Application Discontinuation
- 1996-11-23 TW TW085114455A patent/TW514530B/zh not_active IP Right Cessation
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1997
- 1997-01-03 UY UY24430A patent/UY24430A1/es not_active IP Right Cessation
-
1998
- 1998-05-08 BG BG102439A patent/BG62999B1/bg unknown
- 1998-05-22 NO NO982329A patent/NO982329D0/no unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0563627A3 (cg-RX-API-DMAC7.html) * | 1992-03-05 | 1994-04-27 | Bio Defence Inst Co Ltd | |
| EP0569678A2 (en) * | 1992-03-13 | 1993-11-18 | Yeda Research And Development Co. Ltd. | Double transfectants of MHC genes as cellular vaccines for immunoprevention of tumor metastasis |
Non-Patent Citations (1)
| Title |
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| ECSENBACH and FELDMAN. Genes and antygenes controlling tumer metastasis, Hematology and blood transfusion, Modern Trends in human Leukemia IV, ed R. Neth et al., 1985, рр. 499-507. * |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2556128C2 (ru) * | 2003-08-25 | 2015-07-10 | ЮниВэкс, ЭлЭлСи | Профилактическая противораковая вакцина |
| RU2267326C2 (ru) * | 2004-03-16 | 2006-01-10 | ГУН НИИ онкологии им. проф. Н.Н. Петрова Минздрава РФ | Способ иммунотерапии опухолевым лизатом с адъювантом беталейкин больных солидными опухолями |
| RU2404806C2 (ru) * | 2005-02-23 | 2010-11-27 | Дженентек, Инк. | Продление времени до прогрессирования заболевания или продолжительности жизни у онкологических больных с применением ингибиторов димеризации her |
| US11504421B2 (en) | 2017-05-08 | 2022-11-22 | Gritstone Bio, Inc. | Alphavirus neoantigen vectors |
| US11510973B2 (en) | 2017-05-08 | 2022-11-29 | Gritstone Bio, Inc. | Alphavirus antigen vectors |
| RU2803566C2 (ru) * | 2017-05-08 | 2023-09-15 | Гритстоун Био, Инк. | Неоантигенные векторы на основе альфавируса |
| US12109257B2 (en) | 2017-05-08 | 2024-10-08 | Gritstone Bio, Inc. | Alphavirus neoantigen vectors |
| US11591619B2 (en) | 2019-05-30 | 2023-02-28 | Gritstone Bio, Inc. | Modified adenoviruses |
| US12098383B2 (en) | 2019-05-30 | 2024-09-24 | Gritstone Bio, Inc. | Modified adenoviruses |
| US11771747B2 (en) | 2020-08-06 | 2023-10-03 | Gritstone Bio, Inc. | Multiepitope vaccine cassettes |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2238176A1 (en) | 1997-05-29 |
| CO4520254A1 (es) | 1997-10-15 |
| NZ322910A (en) | 2000-05-26 |
| EP0866851A1 (de) | 1998-09-30 |
| HUP0000318A3 (en) | 2002-02-28 |
| CN1202931A (zh) | 1998-12-23 |
| EE9800161A (et) | 1998-12-15 |
| EE03778B1 (et) | 2002-06-17 |
| BG102439A (en) | 1999-01-29 |
| RO115275B1 (ro) | 1999-12-30 |
| WO1997019169A1 (de) | 1997-05-29 |
| TR199800912T2 (xx) | 1998-08-21 |
| AU7694796A (en) | 1997-06-11 |
| PL326756A1 (en) | 1998-10-26 |
| BG62999B1 (bg) | 2001-01-31 |
| AU720131B2 (en) | 2000-05-25 |
| UY24367A1 (es) | 2000-10-31 |
| HUP0000318A2 (hu) | 2000-06-28 |
| JP2000502052A (ja) | 2000-02-22 |
| TW514530B (en) | 2002-12-21 |
| NO982329D0 (no) | 1998-05-22 |
| KR19990067653A (ko) | 1999-08-25 |
| CZ158998A3 (cs) | 1999-06-16 |
| AR004341A1 (es) | 1998-11-04 |
| SK66998A3 (en) | 1998-12-02 |
| BR9611466A (pt) | 1999-05-18 |
| PL188537B1 (pl) | 2005-02-28 |
| US20020085997A1 (en) | 2002-07-04 |
| UY24430A1 (es) | 1997-07-01 |
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