RU2200738C2 - Способ синтеза нуклеозидных аналогов - Google Patents

Способ синтеза нуклеозидных аналогов Download PDF

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Publication number
RU2200738C2
RU2200738C2 RU2000111438/04A RU2000111438A RU2200738C2 RU 2200738 C2 RU2200738 C2 RU 2200738C2 RU 2000111438/04 A RU2000111438/04 A RU 2000111438/04A RU 2000111438 A RU2000111438 A RU 2000111438A RU 2200738 C2 RU2200738 C2 RU 2200738C2
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Russia
Prior art keywords
heterocycle
group
dmso
alkylidene
phenyl
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RU2000111438/04A
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English (en)
Russian (ru)
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RU2000111438A (ru
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Роберт Вилль м СКОТТ (US)
Роберт Вилльям СКОТТ
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Пфайзер Продактс Инк.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/14—Pyrrolo-pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
RU2000111438/04A 1999-05-11 2000-05-10 Способ синтеза нуклеозидных аналогов RU2200738C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13365199P 1999-05-11 1999-05-11
US60/133,651 1999-05-11

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Publication Number Publication Date
RU2000111438A RU2000111438A (ru) 2002-03-10
RU2200738C2 true RU2200738C2 (ru) 2003-03-20

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RU2000111438/04A RU2200738C2 (ru) 1999-05-11 2000-05-10 Способ синтеза нуклеозидных аналогов

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US (1) US6271370B1 (enExample)
EP (1) EP1052264B1 (enExample)
JP (1) JP2001011092A (enExample)
KR (1) KR100403900B1 (enExample)
CN (1) CN1275575A (enExample)
AR (1) AR028991A1 (enExample)
AT (1) ATE291582T1 (enExample)
AU (1) AU3401100A (enExample)
BR (1) BR0002089A (enExample)
CA (1) CA2307951A1 (enExample)
CZ (1) CZ20001710A3 (enExample)
DE (1) DE60018833D1 (enExample)
HU (1) HUP0001843A3 (enExample)
ID (1) ID25992A (enExample)
IL (1) IL136027A0 (enExample)
IN (1) IN186850B (enExample)
MX (1) MXPA00004532A (enExample)
PL (1) PL340109A1 (enExample)
RU (1) RU2200738C2 (enExample)
TR (1) TR200001340A2 (enExample)
YU (1) YU25500A (enExample)
ZA (1) ZA200002263B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2407747C2 (ru) * 2004-07-21 2010-12-27 Фармассет, Инк. Способ получения алкилзамещенных 2-дезокси-2-фтор-d-рибофуранозил-пиримидинов и пуринов и их производных

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2407747C2 (ru) * 2004-07-21 2010-12-27 Фармассет, Инк. Способ получения алкилзамещенных 2-дезокси-2-фтор-d-рибофуранозил-пиримидинов и пуринов и их производных

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TR200001340A2 (tr) 2000-12-21
IL136027A0 (en) 2001-05-20
IN186850B (enExample) 2001-11-24
CZ20001710A3 (cs) 2001-09-12
ID25992A (id) 2000-11-16
US6271370B1 (en) 2001-08-07
HUP0001843A2 (hu) 2001-06-28
YU25500A (sh) 2003-08-29
MXPA00004532A (es) 2002-03-08
KR20010069193A (ko) 2001-07-23
AR028991A1 (es) 2003-06-04
ZA200002263B (en) 2001-12-24
BR0002089A (pt) 2001-01-02
JP2001011092A (ja) 2001-01-16
EP1052264A2 (en) 2000-11-15
HU0001843D0 (en) 2000-07-28
ATE291582T1 (de) 2005-04-15
CN1275575A (zh) 2000-12-06
HUP0001843A3 (en) 2001-09-28
PL340109A1 (en) 2000-11-20
AU3401100A (en) 2000-11-16
EP1052264A3 (en) 2001-06-13
CA2307951A1 (en) 2000-11-11
KR100403900B1 (ko) 2003-11-01
DE60018833D1 (de) 2005-04-28
EP1052264B1 (en) 2005-03-23

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