RU2197485C2 - Полиморфные формы 8-хлор-6,11-дигидро-11-(4-пиперидилиден)-5h-бензо[5,6]циклогепта[1,2-b]пир идина - Google Patents

Полиморфные формы 8-хлор-6,11-дигидро-11-(4-пиперидилиден)-5h-бензо[5,6]циклогепта[1,2-b]пир идина Download PDF

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RU2197485C2
RU2197485C2 RU2000102669/04A RU2000102669A RU2197485C2 RU 2197485 C2 RU2197485 C2 RU 2197485C2 RU 2000102669/04 A RU2000102669/04 A RU 2000102669/04A RU 2000102669 A RU2000102669 A RU 2000102669A RU 2197485 C2 RU2197485 C2 RU 2197485C2
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Russia
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vwd
polymorphic form
crystalline
descarbonyl
ethoxyl
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RU2000102669/04A
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English (en)
Russian (ru)
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RU2000102669A (ru
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Дорис П. ШУМАХЕР (US)
Дорис П. ШУМАХЕР
Юнинг ЛИ (US)
Юнинг ЛИ
Лоренс Р. РОУГЕРС (US)
Лоренс Р. РОУГЕРС
Чарльз Дж. ЭКХАРТ (US)
Чарльз Дж. ЭКХАРТ
Нанешва С. СОВАНТ (US)
Нанешва С. СОВАНТ
Мхаель Б. МЕЙЧЕЛ (US)
Мхаель Б. МЕЙЧЕЛ
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Шеринг Корпорейшн
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
RU2000102669/04A 1997-07-02 1998-07-01 Полиморфные формы 8-хлор-6,11-дигидро-11-(4-пиперидилиден)-5h-бензо[5,6]циклогепта[1,2-b]пир идина RU2197485C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88676697A 1997-07-02 1997-07-02
US08/886,766 1997-07-02

Publications (2)

Publication Number Publication Date
RU2000102669A RU2000102669A (ru) 2001-10-27
RU2197485C2 true RU2197485C2 (ru) 2003-01-27

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ID=25389724

Family Applications (1)

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RU2000102669/04A RU2197485C2 (ru) 1997-07-02 1998-07-01 Полиморфные формы 8-хлор-6,11-дигидро-11-(4-пиперидилиден)-5h-бензо[5,6]циклогепта[1,2-b]пир идина

Country Status (25)

Country Link
EP (1) EP0993455B1 (https=)
JP (2) JP2002507991A (https=)
KR (1) KR20010014316A (https=)
CN (1) CN1261886A (https=)
AR (1) AR013161A1 (https=)
AT (1) ATE239010T1 (https=)
AU (1) AU734487B2 (https=)
BR (1) BR9811658A (https=)
CA (1) CA2294352C (https=)
CO (1) CO4940423A1 (https=)
DE (1) DE69814076T2 (https=)
ES (1) ES2197480T3 (https=)
HU (1) HUP0004308A3 (https=)
IL (1) IL133387A (https=)
MY (1) MY132943A (https=)
NO (1) NO996547L (https=)
NZ (1) NZ501417A (https=)
PE (1) PE86399A1 (https=)
PL (1) PL337712A1 (https=)
RU (1) RU2197485C2 (https=)
SK (1) SK185299A3 (https=)
TR (1) TR199903308T2 (https=)
UA (1) UA62976C2 (https=)
WO (1) WO1999001450A1 (https=)
ZA (1) ZA985783B (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7405223B2 (en) 2000-02-03 2008-07-29 Schering Corporation Treating allergic and inflammatory conditions
US7678908B2 (en) * 2002-04-15 2010-03-16 Sun Pharmaceutical Industries Limited Process of preparing desaloratadine
WO2004012738A1 (en) * 2002-08-05 2004-02-12 Sandoz Ag Novel salt and polymorphs of desloratadine hemifumarate
US20060135547A1 (en) * 2003-03-12 2006-06-22 Toth Zoltan G Stable pharmaceutical compositions of desloratadine and processes for preparation of polymorphic forms of desloratadine
WO2004080461A2 (en) * 2003-03-12 2004-09-23 TEVA Gyógyszergyár Részvénytársaság Stable pharmaceutical compositions of desloratadine
SK50112007A3 (sk) * 2004-07-07 2007-07-06 Egis Gy�gyszergy�r Nyrt. Nový pseudopolymorf desloratadínu vytvorený s oxidom uhličitým
TW200735871A (en) * 2005-11-17 2007-10-01 Teva Pharma Desloratadine crystalline forms mixtures having a low level of residual solvents
HU230417B1 (hu) * 2006-10-26 2016-05-30 Egis Gyógyszergyár Zrt Eljárás desloratadine szén-dioxiddal képezett adduktjának előállítására
EP2164470A1 (en) * 2007-05-11 2010-03-24 ratiopharm GmbH Pharmaceutical composition comprising desloratadine
EP2269586B1 (en) 2009-07-01 2011-09-21 Alfred E. Tiefenbacher (GmbH & Co. KG) Pharmaceutical composition comprising desloratadine
PT2568970T (pt) 2010-05-10 2019-02-11 Lesvi Laboratorios Sl Formulações farmacêuticas estáveis contendo um anti-histamínico
EP2727592A1 (en) 2012-11-05 2014-05-07 Kücükgüzel, Sükriye Güniz A combination of desloratadine and paracetamol
CN103755682A (zh) * 2013-12-30 2014-04-30 山东达因海洋生物制药股份有限公司 一种地氯雷他定新晶型及制备方法
CN108358892A (zh) * 2018-04-11 2018-08-03 常州方圆制药有限公司 一种地氯雷他定粗品的提纯方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4659716A (en) * 1984-02-15 1987-04-21 Schering Corporation Antihistaminic 8-(halo)-substituted 6,11-dihydro-11-(4-piperidylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridines
RU92016540A (ru) * 1990-06-22 1995-03-27 Шеринг Корпорейшн Производные бис-бензо- или бензопиридоциклогептапиперидина, пиперидилидена и пиперазина, фармацевтическая композиция, способ лечения, применение соединения и способ получения соединения

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0208855B1 (en) * 1985-05-13 1991-03-06 Schering Corporation process for preparing piperidylidene dihydrodibenzo(a,d)cycloheptenes and aza derivatives thereof, compounds obtained by such process and the use of such compounds for preparing useful pharmaceutical compositions
IE68935B1 (en) * 1990-06-22 1996-07-24 Schering Corp Bis-benzo or benzopyrido cyclohepta piperidene piperidylidene and piperazine compounds compositions and methods of use

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4659716A (en) * 1984-02-15 1987-04-21 Schering Corporation Antihistaminic 8-(halo)-substituted 6,11-dihydro-11-(4-piperidylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridines
RU92016540A (ru) * 1990-06-22 1995-03-27 Шеринг Корпорейшн Производные бис-бензо- или бензопиридоциклогептапиперидина, пиперидилидена и пиперазина, фармацевтическая композиция, способ лечения, применение соединения и способ получения соединения

Also Published As

Publication number Publication date
HUP0004308A3 (en) 2004-07-28
EP0993455A1 (en) 2000-04-19
DE69814076T2 (de) 2004-02-26
SK185299A3 (en) 2000-07-11
AR013161A1 (es) 2000-12-13
PL337712A1 (en) 2000-08-28
PE86399A1 (es) 1999-10-23
ES2197480T3 (es) 2004-01-01
ATE239010T1 (de) 2003-05-15
BR9811658A (pt) 2000-09-05
UA62976C2 (en) 2004-01-15
HUP0004308A2 (hu) 2001-10-28
CN1261886A (zh) 2000-08-02
MY132943A (en) 2007-10-31
JP2002507991A (ja) 2002-03-12
CO4940423A1 (es) 2000-07-24
NO996547L (no) 2000-03-01
ZA985783B (en) 1999-01-19
AU8271098A (en) 1999-01-25
NZ501417A (en) 2000-10-27
NO996547D0 (no) 1999-12-29
TR199903308T2 (xx) 2000-11-21
KR20010014316A (ko) 2001-02-26
WO1999001450A1 (en) 1999-01-14
IL133387A (en) 2004-02-08
DE69814076D1 (de) 2003-06-05
HK1024687A1 (en) 2000-10-20
AU734487B2 (en) 2001-06-14
JP2009242436A (ja) 2009-10-22
IL133387A0 (en) 2001-04-30
CA2294352A1 (en) 1999-01-14
CA2294352C (en) 2008-05-06
EP0993455B1 (en) 2003-05-02

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