NZ501417A - Crystalline polymorphs of descarbonylethoxyloratadine (8-chloro-6, 11-dihydro-11-(4-piperidylidene)-5H-benzo[5,6] cyclohepta[1,2-b]pyridine) and methods for their use - Google Patents
Crystalline polymorphs of descarbonylethoxyloratadine (8-chloro-6, 11-dihydro-11-(4-piperidylidene)-5H-benzo[5,6] cyclohepta[1,2-b]pyridine) and methods for their useInfo
- Publication number
- NZ501417A NZ501417A NZ501417A NZ50141798A NZ501417A NZ 501417 A NZ501417 A NZ 501417A NZ 501417 A NZ501417 A NZ 501417A NZ 50141798 A NZ50141798 A NZ 50141798A NZ 501417 A NZ501417 A NZ 501417A
- Authority
- NZ
- New Zealand
- Prior art keywords
- descarbonylethoxyloratadine
- piperidylidene
- cyclohepta
- benzo
- dihydro
- Prior art date
Links
- JAUOIFJMECXRGI-UHFFFAOYSA-N Neoclaritin Chemical compound C=1C(Cl)=CC=C2C=1CCC1=CC=CN=C1C2=C1CCNCC1 JAUOIFJMECXRGI-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88676697A | 1997-07-02 | 1997-07-02 | |
| PCT/US1998/013433 WO1999001450A1 (en) | 1997-07-02 | 1998-07-01 | POLYMORPHS OF 8-CHLORO-6, 11-DIHYDRO-11- (4-PIPERIDYLIDENE) -5H-BENZO[5,6] CYCLOHEPTA[1,2-b]PYRIDINE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ501417A true NZ501417A (en) | 2000-10-27 |
Family
ID=25389724
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ501417A NZ501417A (en) | 1997-07-02 | 1998-07-01 | Crystalline polymorphs of descarbonylethoxyloratadine (8-chloro-6, 11-dihydro-11-(4-piperidylidene)-5H-benzo[5,6] cyclohepta[1,2-b]pyridine) and methods for their use |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP0993455B1 (https=) |
| JP (2) | JP2002507991A (https=) |
| KR (1) | KR20010014316A (https=) |
| CN (1) | CN1261886A (https=) |
| AR (1) | AR013161A1 (https=) |
| AT (1) | ATE239010T1 (https=) |
| AU (1) | AU734487B2 (https=) |
| BR (1) | BR9811658A (https=) |
| CA (1) | CA2294352C (https=) |
| CO (1) | CO4940423A1 (https=) |
| DE (1) | DE69814076T2 (https=) |
| ES (1) | ES2197480T3 (https=) |
| HU (1) | HUP0004308A3 (https=) |
| IL (1) | IL133387A (https=) |
| MY (1) | MY132943A (https=) |
| NO (1) | NO996547L (https=) |
| NZ (1) | NZ501417A (https=) |
| PE (1) | PE86399A1 (https=) |
| PL (1) | PL337712A1 (https=) |
| RU (1) | RU2197485C2 (https=) |
| SK (1) | SK185299A3 (https=) |
| TR (1) | TR199903308T2 (https=) |
| UA (1) | UA62976C2 (https=) |
| WO (1) | WO1999001450A1 (https=) |
| ZA (1) | ZA985783B (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7405223B2 (en) | 2000-02-03 | 2008-07-29 | Schering Corporation | Treating allergic and inflammatory conditions |
| US7678908B2 (en) * | 2002-04-15 | 2010-03-16 | Sun Pharmaceutical Industries Limited | Process of preparing desaloratadine |
| WO2004012738A1 (en) * | 2002-08-05 | 2004-02-12 | Sandoz Ag | Novel salt and polymorphs of desloratadine hemifumarate |
| US20060135547A1 (en) * | 2003-03-12 | 2006-06-22 | Toth Zoltan G | Stable pharmaceutical compositions of desloratadine and processes for preparation of polymorphic forms of desloratadine |
| WO2004080461A2 (en) * | 2003-03-12 | 2004-09-23 | TEVA Gyógyszergyár Részvénytársaság | Stable pharmaceutical compositions of desloratadine |
| SK50112007A3 (sk) * | 2004-07-07 | 2007-07-06 | Egis Gy�gyszergy�r Nyrt. | Nový pseudopolymorf desloratadínu vytvorený s oxidom uhličitým |
| TW200735871A (en) * | 2005-11-17 | 2007-10-01 | Teva Pharma | Desloratadine crystalline forms mixtures having a low level of residual solvents |
| HU230417B1 (hu) * | 2006-10-26 | 2016-05-30 | Egis Gyógyszergyár Zrt | Eljárás desloratadine szén-dioxiddal képezett adduktjának előállítására |
| EP2164470A1 (en) * | 2007-05-11 | 2010-03-24 | ratiopharm GmbH | Pharmaceutical composition comprising desloratadine |
| EP2269586B1 (en) | 2009-07-01 | 2011-09-21 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Pharmaceutical composition comprising desloratadine |
| PT2568970T (pt) | 2010-05-10 | 2019-02-11 | Lesvi Laboratorios Sl | Formulações farmacêuticas estáveis contendo um anti-histamínico |
| EP2727592A1 (en) | 2012-11-05 | 2014-05-07 | Kücükgüzel, Sükriye Güniz | A combination of desloratadine and paracetamol |
| CN103755682A (zh) * | 2013-12-30 | 2014-04-30 | 山东达因海洋生物制药股份有限公司 | 一种地氯雷他定新晶型及制备方法 |
| CN108358892A (zh) * | 2018-04-11 | 2018-08-03 | 常州方圆制药有限公司 | 一种地氯雷他定粗品的提纯方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1985003707A1 (en) * | 1984-02-15 | 1985-08-29 | Schering Corporation | 8-CHLORO-6,11-DIHYDRO-11-(4-PIPERIDYLIDENE)-5H-BENZO AD5,6 BDCYCLOHEPTA AD1,2-b BDPYRIDINE AND ITS SALTS, PROCESSES FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS |
| EP0208855B1 (en) * | 1985-05-13 | 1991-03-06 | Schering Corporation | process for preparing piperidylidene dihydrodibenzo(a,d)cycloheptenes and aza derivatives thereof, compounds obtained by such process and the use of such compounds for preparing useful pharmaceutical compositions |
| IE68935B1 (en) * | 1990-06-22 | 1996-07-24 | Schering Corp | Bis-benzo or benzopyrido cyclohepta piperidene piperidylidene and piperazine compounds compositions and methods of use |
-
1998
- 1998-01-07 UA UA2000010519A patent/UA62976C2/uk unknown
- 1998-07-01 PL PL98337712A patent/PL337712A1/xx unknown
- 1998-07-01 AT AT98932930T patent/ATE239010T1/de not_active IP Right Cessation
- 1998-07-01 EP EP98932930A patent/EP0993455B1/en not_active Expired - Lifetime
- 1998-07-01 IL IL13338798A patent/IL133387A/en not_active IP Right Cessation
- 1998-07-01 ES ES98932930T patent/ES2197480T3/es not_active Expired - Lifetime
- 1998-07-01 BR BR9811658-4A patent/BR9811658A/pt not_active IP Right Cessation
- 1998-07-01 CO CO98037139A patent/CO4940423A1/es unknown
- 1998-07-01 AR ARP980103203A patent/AR013161A1/es unknown
- 1998-07-01 KR KR1019997012456A patent/KR20010014316A/ko not_active Ceased
- 1998-07-01 HU HU0004308A patent/HUP0004308A3/hu unknown
- 1998-07-01 CN CN98806712A patent/CN1261886A/zh active Pending
- 1998-07-01 TR TR1999/03308T patent/TR199903308T2/xx unknown
- 1998-07-01 RU RU2000102669/04A patent/RU2197485C2/ru not_active IP Right Cessation
- 1998-07-01 NZ NZ501417A patent/NZ501417A/xx unknown
- 1998-07-01 DE DE69814076T patent/DE69814076T2/de not_active Expired - Lifetime
- 1998-07-01 JP JP50726599A patent/JP2002507991A/ja active Pending
- 1998-07-01 AU AU82710/98A patent/AU734487B2/en not_active Ceased
- 1998-07-01 CA CA002294352A patent/CA2294352C/en not_active Expired - Fee Related
- 1998-07-01 WO PCT/US1998/013433 patent/WO1999001450A1/en not_active Ceased
- 1998-07-01 ZA ZA985783A patent/ZA985783B/xx unknown
- 1998-07-01 SK SK1852-99A patent/SK185299A3/sk unknown
- 1998-07-02 MY MYPI98003024A patent/MY132943A/en unknown
- 1998-07-02 PE PE1998000594A patent/PE86399A1/es not_active Application Discontinuation
-
1999
- 1999-12-29 NO NO996547A patent/NO996547L/no not_active Application Discontinuation
-
2009
- 2009-07-27 JP JP2009174701A patent/JP2009242436A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0004308A3 (en) | 2004-07-28 |
| EP0993455A1 (en) | 2000-04-19 |
| DE69814076T2 (de) | 2004-02-26 |
| SK185299A3 (en) | 2000-07-11 |
| AR013161A1 (es) | 2000-12-13 |
| PL337712A1 (en) | 2000-08-28 |
| PE86399A1 (es) | 1999-10-23 |
| ES2197480T3 (es) | 2004-01-01 |
| ATE239010T1 (de) | 2003-05-15 |
| BR9811658A (pt) | 2000-09-05 |
| UA62976C2 (en) | 2004-01-15 |
| HUP0004308A2 (hu) | 2001-10-28 |
| CN1261886A (zh) | 2000-08-02 |
| MY132943A (en) | 2007-10-31 |
| JP2002507991A (ja) | 2002-03-12 |
| CO4940423A1 (es) | 2000-07-24 |
| NO996547L (no) | 2000-03-01 |
| ZA985783B (en) | 1999-01-19 |
| AU8271098A (en) | 1999-01-25 |
| NO996547D0 (no) | 1999-12-29 |
| TR199903308T2 (xx) | 2000-11-21 |
| KR20010014316A (ko) | 2001-02-26 |
| WO1999001450A1 (en) | 1999-01-14 |
| IL133387A (en) | 2004-02-08 |
| DE69814076D1 (de) | 2003-06-05 |
| HK1024687A1 (en) | 2000-10-20 |
| AU734487B2 (en) | 2001-06-14 |
| JP2009242436A (ja) | 2009-10-22 |
| IL133387A0 (en) | 2001-04-30 |
| CA2294352A1 (en) | 1999-01-14 |
| CA2294352C (en) | 2008-05-06 |
| RU2197485C2 (ru) | 2003-01-27 |
| EP0993455B1 (en) | 2003-05-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RENW | Renewal (renewal fees accepted) |