RU2114120C1 - Белок, связывающий инсулин-подобный фактор роста, фармацевтическая композиция - Google Patents

Белок, связывающий инсулин-подобный фактор роста, фармацевтическая композиция Download PDF

Info

Publication number
RU2114120C1
RU2114120C1 RU93058185A RU93058185A RU2114120C1 RU 2114120 C1 RU2114120 C1 RU 2114120C1 RU 93058185 A RU93058185 A RU 93058185A RU 93058185 A RU93058185 A RU 93058185A RU 2114120 C1 RU2114120 C1 RU 2114120C1
Authority
RU
Russia
Prior art keywords
igf
bsifr
protein
bsif
bone
Prior art date
Application number
RU93058185A
Other languages
English (en)
Russian (ru)
Other versions
RU93058185A (ru
Inventor
Мохан Суббураман
Дж.Бэйлинк Дэвид
Original Assignee
Берингер Маннхайм ГмбХ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Берингер Маннхайм ГмбХ filed Critical Берингер Маннхайм ГмбХ
Publication of RU93058185A publication Critical patent/RU93058185A/ru
Application granted granted Critical
Publication of RU2114120C1 publication Critical patent/RU2114120C1/ru

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4743—Insulin-like growth factor binding protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
RU93058185A 1991-04-19 1992-04-15 Белок, связывающий инсулин-подобный фактор роста, фармацевтическая композиция RU2114120C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68835391A 1991-04-19 1991-04-19
US688353 1991-04-19
US688,353 1991-04-19

Publications (2)

Publication Number Publication Date
RU93058185A RU93058185A (ru) 1996-11-10
RU2114120C1 true RU2114120C1 (ru) 1998-06-27

Family

ID=24764088

Family Applications (1)

Application Number Title Priority Date Filing Date
RU93058185A RU2114120C1 (ru) 1991-04-19 1992-04-15 Белок, связывающий инсулин-подобный фактор роста, фармацевтическая композиция

Country Status (11)

Country Link
EP (1) EP0580752A4 (fr)
JP (1) JP2527896B2 (fr)
KR (1) KR0129864B1 (fr)
AU (1) AU658187B2 (fr)
CA (1) CA2107475A1 (fr)
CZ (1) CZ283601B6 (fr)
FI (1) FI934588A0 (fr)
HU (1) HUT70297A (fr)
NO (1) NO933742L (fr)
RU (1) RU2114120C1 (fr)
WO (1) WO1992018154A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8642037B2 (en) 2001-01-05 2014-02-04 Amgen Fremont Inc. Antibodies to insulin-like growth factor I receptor

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69233155T2 (de) 1991-01-08 2004-06-03 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Insulinartigen wachstumsfaktor bindendes protein
US5643867A (en) * 1992-08-26 1997-07-01 Celtrix Pharmaceuticals, Inc. Method for treating catabolic conditions
US5407913A (en) * 1992-12-03 1995-04-18 Celtrix Pharmaceuticals, Inc. Method and composition for systemic treatment of tissue injury
US6124259A (en) * 1993-01-28 2000-09-26 Celtrix Pharmaceuticals, Inc. Method for treating ophthalmic disorders with IGFBP
EP0800530A4 (fr) * 1994-07-20 1998-12-02 Celtrix Pharma Complexe igf/igfbp destines a favoriser la formation osseuse et a reguler le remodelage osseux
ES2293137T3 (es) 1995-10-11 2008-03-16 Novartis Vaccines And Diagnostics, Inc. Combinacion de pdgf, kgf,igf e igfbp para curacion de heridas.
US20190018025A1 (en) * 2015-12-31 2019-01-17 Siemens Healthcare Diagnostics Inc. Non-recombinant human insulin-like growth factor binding protein concentrate
US10212614B2 (en) * 2015-12-31 2019-02-19 Facebook, Inc. Igniting network nodes in a multi-hop wireless network

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7907958A (nl) * 1979-10-30 1981-06-01 Wijn Adriaan Jacques De Kar of onderstel voorzien van opklapbare wielen.
IL68218A (en) * 1983-03-23 1985-12-31 Univ Ramot Compositions for cartilage repair comprising embryonal chondrocytes
ATE112684T1 (de) * 1987-04-28 1994-10-15 Boehringer Mannheim Gmbh Verwendung von igf-ii zur behandlung von knochenkrankheiten.

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Proc. Natl. Acad. Sci., USA, v. 86, p. 8338 - 8342, 1989. *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8642037B2 (en) 2001-01-05 2014-02-04 Amgen Fremont Inc. Antibodies to insulin-like growth factor I receptor
US9234041B2 (en) 2001-01-05 2016-01-12 Pfizer Inc. Antibodies to insulin-like growth factor I receptor

Also Published As

Publication number Publication date
JP2527896B2 (ja) 1996-08-28
NO933742L (no) 1993-10-18
CA2107475A1 (fr) 1992-10-20
JPH06501270A (ja) 1994-02-10
WO1992018154A1 (fr) 1992-10-29
AU1784492A (en) 1992-11-17
FI934588A (fi) 1993-10-18
KR0129864B1 (en) 1998-04-09
AU658187B2 (en) 1995-04-06
CZ219093A3 (en) 1994-12-15
EP0580752A4 (en) 1994-08-24
CZ283601B6 (cs) 1998-05-13
FI934588A0 (fi) 1993-10-18
HU9302942D0 (en) 1994-01-28
HUT70297A (en) 1995-09-28
EP0580752A1 (fr) 1994-02-02

Similar Documents

Publication Publication Date Title
Wolf et al. Antibodies against transforming growth factor-beta 1 suppress intimal hyperplasia in a rat model.
EP0616536B1 (fr) Utilisation de décorine ou de biglycane pour la fabrication d'un médicament destiné au traitement de la pathologie associée au diabète
EP0494264B1 (fr) Inhibition de facteur de croissance a transformation afin d'empecher l'accumulation de matrice extracellulaire
JP3053116B2 (ja) 医薬組成物
EP0559769B1 (fr) Mitogene de liaison d'heparine presentant une homologie avec le facteur de croissance epidermique (egf)
EP0369943B1 (fr) Protéines de liaison pour facteurs de croissance semblables à l'insuline
JP2648951B2 (ja) 人体のソマトメジン担体蛋白質サブユニットとこれらの製法
JPH05506030A (ja) 哺乳動物に組織修復促進の傾向を与える方法
KR19990066981A (ko) 치료용 맥관형성억제 조성물 및 방법
US7795215B2 (en) MNTF peptides and compositions and methods of use
RU2114120C1 (ru) Белок, связывающий инсулин-подобный фактор роста, фармацевтическая композиция
Phillips et al. Nutrition and somatomedin. XI. Studies of somatomedin inhibitors in rats with streptozotocin-induced diabetes
WO1998004245A1 (fr) Utilisation de modulateurs de la transglutaminase pour favoriser la cicatrisation
Eisenstein et al. Growth inhibitory activities in avascular tissues are recognized by anti-transforming growth factor β antibodies
EP0384731B1 (fr) Facteurs de croissance ostéogéniques identifiés à partir de moelle osseuse régénératrice
JP2004008027A (ja) ｃＡＭＰの産生活性を有する新規ペプチド
WO1999049894A1 (fr) Antagonistes du gene 6 specifique de l'arret de croissance, et leur utilisation contre des troubles insulinoresistants
US5693754A (en) Inhibitory binding protein for insulin-like growth factors
EP0771877A1 (fr) Codage genique pour le recepteur modifie de la proteine morphogenetique osseuse
CA1295940C (fr) Traitement therapeutique de la croissance anormale de cellules avec proteine de regulation des follicules
US20030223984A1 (en) Proteases from carica having mitogenic activity and their methods of use
AU2079900A (en) Inhibiting transforming growth factor beta to prevent accumulation of extracellular matrix
WO1992013888A1 (fr) Compositions et procede de cicatrisation des cellules epitheliales