RU2019144960A - Мультибиотические средства и способы их применения - Google Patents

Мультибиотические средства и способы их применения Download PDF

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RU2019144960A
RU2019144960A RU2019144960A RU2019144960A RU2019144960A RU 2019144960 A RU2019144960 A RU 2019144960A RU 2019144960 A RU2019144960 A RU 2019144960A RU 2019144960 A RU2019144960 A RU 2019144960A RU 2019144960 A RU2019144960 A RU 2019144960A
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multibiotic
agent
compound
following structure
salt
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RU2019144960A
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RU2019144960A3 (ru
Inventor
Мл. Джон Патрик КЕЙСИ
Дэвид Берри
Альфредо Кастро
Стивен Дж. ТЕЙЛОР
Фердинанд Е. МАССАРИ
Джон ПРАУДФУТ
Элайджа БОГАРТ
Тимоти Ф. БРИГГС
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Флэгшип Пайониринг Инновейшнз V, Инк.
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Publication of RU2019144960A publication Critical patent/RU2019144960A/ru
Publication of RU2019144960A3 publication Critical patent/RU2019144960A3/ru

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    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
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Claims (32)

1. Мультибиотическое средство, содержащее три или более фрагментов, которые независимо представляют собой спиртовые ядра или ацилы, при условии, что мультибиотическое средство содержит по меньшей мере три различных фрагмента и что фрагменты связаны одной или несколькими сложноэфирными или гликозидными связями,
причем каждое спиртовое ядро независимо представляет собой углевод или его олигомер, месаламин, холин или эфедрин, причем каждый углевод или его олигомер представляет собой ксилозу, арабинозу, фруктозу, галактозу, глюкозинолат, рибозу или ее олигомер; трегалозу; лактулозу; или гиалуроновую кислоту;
причем каждый ацил независимо представляет собой ацил короткоцепочечной жирной кислоты, ацил β-гидроксибутирата, ацил ацетоацетата, ацил индол-3-уксусной кислоты, ацил индол-3-пропионовой кислоты или ацил 3-(индол-3-ил)-акриловой кислоты.
2. Мультибиотическое средство по п. 1, где мультибиотическое средство выбрано из группы, состоящей из соединений со следующей структурой:
Figure 00000001
Figure 00000002
, и их солей.
3. Мультибиотическое средство по п. 1, где мультибиотическое средство представляет собой соединение со следующей структурой:
Figure 00000003
,
или его соль.
4. Мультибиотическое средство по п. 1, где мультибиотическое средство представляет собой соединение со следующей структурой:
Figure 00000004
,
или его соль.
5. Мультибиотическое средство по п. 1, где мультибиотическое средство представляет собой соединение со следующей структурой:
Figure 00000005
,
или его соль.
6. Мультибиотическое средство по п. 1, где мультибиотическое средство представляет собой соединение со следующей структурой:
Figure 00000006
,
или его соль.
7. Мультибиотическое средство по п. 1, где мультибиотическое средство представляет собой соединение со следующей структурой:
Figure 00000007
,
или его соль.
8. Мультибиотическое средство по п. 1, где мультибиотическое средство представляет собой соединение со следующей структурой:
Figure 00000008
,
или его соль.
9. Мультибиотическое средство по п. 1, где мультибиотическое средство представляет собой соединение со следующей структурой:
Figure 00000002
,
или его соль.
10. Фармацевтическая композиция, содержащая мультибиотическое средство по любому из пп.1-9 и фармацевтически приемлемое вспомогательное вещество.
11. Нутрицевтическая композиция, содержащая мультибиотическое средство по любому из пп.1-9 и физиологически приемлемое вспомогательное вещество.
12. Мультибиотическое средство по любому из пп.1-9 для применения в доставке биологически активного соединения к целевому участку у субъекта.
13. Мультибиотическое средство для применения по п.12, где мультибиотическое средство вводят перорально.
14. Мультибиотическое средство для применения по п.12, где мультибиотическое средство по существу активируется микробиотой субъекта.
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