RU2019110782A - Сополимер и медицинский материал, содержащий его - Google Patents

Сополимер и медицинский материал, содержащий его Download PDF

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RU2019110782A
RU2019110782A RU2019110782A RU2019110782A RU2019110782A RU 2019110782 A RU2019110782 A RU 2019110782A RU 2019110782 A RU2019110782 A RU 2019110782A RU 2019110782 A RU2019110782 A RU 2019110782A RU 2019110782 A RU2019110782 A RU 2019110782A
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Сугуру УСИРО
Акихиро ХАЯСИ
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Торэй Индастриз, Инк.
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Claims (22)

1. Сополимер, содержащий мономерное звено A, мономерное звено B и мономерное звено C, которые представлены общей формулой (I), представленной далее,
в которой молярная фракция мономерного звена C на основе всех мономерных звеньев, которые образуют сополимер, составляет от 0,5 до 40%:
[Химическая формула 1]
Figure 00000001
где RA представляет функциональную группу, имеющую амидную связь, RB представляет алкил или алкенил, имеющий от 2 до 20 атомов углерода, RC представляет алкил или алкенил, где произвольный атом водорода замещают по меньшей мере одной функциональной группой, выбранной из группы, состоящей из аминогруппы, азидогруппы, иминогруппы, карбоксигруппы, хлорангидридной группы, кислой ангидридной группы, альдегидной группы, гидроксильной группы, группы фосфорной кислоты, тиоловой группы, изоцианатной группы, тиоизоцианатной группы, эпоксигруппы, галогенированной алкильной группы, цианогруппы, винильной группы, этинильной группы, нитрогруппы и нитрозогруппы и их ионизированных функциональных групп (где произвольный атом углерода в алкиле или алкениле из RC необязательно замещают атомом азота, атомом кислорода или атомом серы), и каждый из X1, X2 и X3 представляет атом водорода или метильную группу.
2. Сополимер по п. 1, в котором мономерное звено A представлено любой одной из общих формул с (II) до (IV), представленных далее:
[Химическая формула 2]
Figure 00000002
где m представляет целое от 1 до 5.
3. Сополимер по п. 1 или 2, в котором мономерное звено A, мономерное звено B и мономерное звено C расположены случайно.
4. Сополимер по любому одному из пп. 1-3, имеющий среднечисловую молекулярную массу от 1000 до 100000.
5. Сополимер по любому одному из пп. 1-4, в котором RC представляет собой алкильную группу, в которой произвольный атом водорода замещают по меньшей мере одной функциональной группой, выбранной из аминогруппы, изоцианатной группы и эпоксигруппы.
6. Медицинский материал, содержащий сополимер по любому одному из пп. 1-5, и материал основы, связанный с сополимером.
7. Медицинский материал по п. 6, в котором материал основы выполняют из полимера, имеющего повторяющееся звено, содержащее сложноэфирную связь в основной цепи.
8. Медицинский материал по п. 6, который дополнительно содержит производное фосфоновой кислоты или производное катехола,
где материал основы выполняют из металла,
сополимер связывают с производным фосфоновой кислоты или производным катехола,
производное фосфоновой кислоты связывают с материалом основы через его группу фосфоновой кислоты, и
производное катехола связывают с материалом основы через его группу катехола.
9. Устройство захвата тромбов, содержащее медицинский материал по любому одному из пп. 6-8.
10. Медицинский материал по п. 6, в котором материал основы выполняют из полимера, часть которого содержит гидроксильную группу или карбоксигруппу, введенную в него, и в котором по меньшей мере один атом водорода в основной цепи замещают атомом хлора, или полимера, часть которого содержит гидроксильную группу или карбоксигруппу, введенную в него, и который имеет силоксановую связь по меньшей мере в его части, и сополимер связывают с материалом основы через гидроксильную группу или карбоксигруппу.
11. Контур циркуляции крови, содержащий медицинский материал по п. 10.
RU2019110782A 2016-09-30 2017-09-20 Сополимер и медицинский материал, содержащий его RU2757274C2 (ru)

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