RU2018109426A - Химерные антигенные рецепторы со встроенными контролируемыми функциями - Google Patents
Химерные антигенные рецепторы со встроенными контролируемыми функциями Download PDFInfo
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- RU2018109426A RU2018109426A RU2018109426A RU2018109426A RU2018109426A RU 2018109426 A RU2018109426 A RU 2018109426A RU 2018109426 A RU2018109426 A RU 2018109426A RU 2018109426 A RU2018109426 A RU 2018109426A RU 2018109426 A RU2018109426 A RU 2018109426A
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
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- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA201570545 | 2015-08-24 | ||
| DKPA201570545 | 2015-08-24 | ||
| EP15202592.0 | 2015-12-23 | ||
| EP15202592 | 2015-12-23 | ||
| PCT/EP2016/069918 WO2017032777A1 (en) | 2015-08-24 | 2016-08-24 | Chimeric antigen receptors with integrated controllable functions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2018109426A true RU2018109426A (ru) | 2019-09-26 |
| RU2018109426A3 RU2018109426A3 (enExample) | 2020-02-28 |
Family
ID=56842804
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2018109426A RU2018109426A (ru) | 2015-08-24 | 2016-08-24 | Химерные антигенные рецепторы со встроенными контролируемыми функциями |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10988542B2 (enExample) |
| EP (1) | EP3341410B1 (enExample) |
| JP (1) | JP6894430B2 (enExample) |
| KR (1) | KR20180042361A (enExample) |
| CN (1) | CN107922498A (enExample) |
| AU (1) | AU2016313082B2 (enExample) |
| BR (1) | BR112018002189A2 (enExample) |
| CA (1) | CA2995632C (enExample) |
| IL (1) | IL257138A (enExample) |
| MX (1) | MX2018001533A (enExample) |
| RU (1) | RU2018109426A (enExample) |
| WO (1) | WO2017032777A1 (enExample) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| EP2948544A4 (en) | 2013-01-28 | 2016-08-03 | St Jude Childrens Res Hospital | CHIMERIC RECEPTOR WITH NKG2D SPECIFICITY FOR CELL THERAPY AGAINST CANCER AND INFECTION DISEASES |
| CA2935960C (en) | 2014-01-08 | 2023-01-10 | Bart Lipkens | Acoustophoresis device with dual acoustophoretic chamber |
| SG11201609118RA (en) | 2014-05-15 | 2016-11-29 | Univ Singapore | Modified natural killer cells and uses thereof |
| US11377651B2 (en) | 2016-10-19 | 2022-07-05 | Flodesign Sonics, Inc. | Cell therapy processes utilizing acoustophoresis |
| US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
| EP3184548A1 (en) * | 2015-12-23 | 2017-06-28 | Miltenyi Biotec GmbH | Chimeric antigen receptor with cytokine receptor activating or blocking domain |
| IL312206A (en) * | 2016-04-15 | 2024-06-01 | Novartis Ag | Preparations and methods for selective protein expression |
| US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
| CN110650743B (zh) * | 2017-03-13 | 2023-12-29 | 波赛达治疗公司 | 用于选择性消除和替换造血干细胞的组合物和方法 |
| RU2019128544A (ru) | 2017-03-27 | 2021-04-28 | Нэшнл Юниверсити Оф Сингапур | Линии стимулирующих клеток для ex vivo размножения и активации клеток-натуральных киллеров |
| CN110636851B (zh) | 2017-03-27 | 2023-11-03 | 新加坡国立大学 | 截短的nkg2d嵌合受体及其在自然杀伤细胞免疫疗法中的用途 |
| JOP20180027A1 (ar) * | 2017-03-28 | 2019-01-30 | Cell Design Labs Inc | بوليبيبتيدات مخلطة و طرق لتغيير موضع الغشاء فيها |
| JP2020512825A (ja) * | 2017-04-12 | 2020-04-30 | ファイザー・インク | 条件的親和性を有する抗体およびその使用の方法 |
| WO2018213848A1 (en) * | 2017-05-19 | 2018-11-22 | The Regents Of The University Of California | Antibody chemically induced dimerizer (abcid) as molecular switches for regulating cellular therapies |
| WO2019010201A1 (en) * | 2017-07-03 | 2019-01-10 | Yale University | REGULATED SMALL MOLECULE ADAPTER |
| CN107312797B (zh) * | 2017-07-28 | 2021-06-18 | 广州中科蓝华生物科技有限公司 | 一种蛋白调控系统及其制备方法和应用 |
| EP3684408A1 (en) | 2017-09-19 | 2020-07-29 | Massachusetts Institute of Technology | Compositions for chimeric antigen receptor t cell therapy and uses thereof |
| SG11202003415XA (en) | 2017-10-18 | 2020-05-28 | Novartis Ag | Compositions and methods for selective protein degradation |
| KR20220066413A (ko) | 2017-12-14 | 2022-05-24 | 프로디자인 소닉스, 인크. | 음향 트랜스듀서 구동기 및 제어기 |
| MA51158A (fr) * | 2017-12-14 | 2020-10-21 | Bluebird Bio Inc | Récepteurs daric nkg2d |
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| CA2995632A1 (en) | 2017-03-02 |
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