CA2995632C - Chimeric antigen receptors with integrated controllable functions - Google Patents
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| US9511092B2 (en) | 2013-01-28 | 2016-12-06 | St. Jude Children's Research Hospital, Inc. | Chimeric receptor with NKG2D specificity for use in cell therapy against cancer and infectious disease |
| US9725710B2 (en) | 2014-01-08 | 2017-08-08 | Flodesign Sonics, Inc. | Acoustophoresis device with dual acoustophoretic chamber |
| KR20210014210A (ko) | 2014-05-15 | 2021-02-08 | 내셔널 유니버시티 오브 싱가포르 | 변형된 천연 살해 세포 및 그의 용도 |
| US11377651B2 (en) | 2016-10-19 | 2022-07-05 | Flodesign Sonics, Inc. | Cell therapy processes utilizing acoustophoresis |
| US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
| EP3184548A1 (en) * | 2015-12-23 | 2017-06-28 | Miltenyi Biotec GmbH | Chimeric antigen receptor with cytokine receptor activating or blocking domain |
| PL3443096T3 (pl) * | 2016-04-15 | 2023-06-19 | Novartis Ag | Kompozycje i sposoby do selektywnej ekspresji chimerycznych receptorów antygenowych |
| US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
| IL311608A (en) | 2017-03-13 | 2024-05-01 | Poseida Therapeutics Inc | Preparations and methods for the selective elimination and replacement of hematopoietic stem cells |
| IL269553B2 (en) | 2017-03-27 | 2025-10-01 | Nat Univ Singapore | Truncated NKG2D chimeric receptors and their uses in immunotherapy with natural killer cells |
| BR112019020001A2 (pt) | 2017-03-27 | 2020-04-28 | Nat Univ Singapore | linhagens celulares estimuladoras para expansão ex vivo e ativação de células exterminadoras naturais |
| JOP20180027A1 (ar) * | 2017-03-28 | 2019-01-30 | Cell Design Labs Inc | بوليبيبتيدات مخلطة و طرق لتغيير موضع الغشاء فيها |
| EP3609915A1 (en) * | 2017-04-12 | 2020-02-19 | Pfizer Inc | Antibodies having conditional affinity and methods of use thereof |
| CN110944647B (zh) * | 2017-05-19 | 2024-10-08 | 加利福尼亚大学董事会 | 作为调节细胞疗法的分子开关的抗体化学诱导二聚体(AbCID) |
| WO2019010201A1 (en) * | 2017-07-03 | 2019-01-10 | Yale University | REGULATED SMALL MOLECULE ADAPTER |
| CN107312797B (zh) * | 2017-07-28 | 2021-06-18 | 广州中科蓝华生物科技有限公司 | 一种蛋白调控系统及其制备方法和应用 |
| JP7654240B2 (ja) | 2017-09-19 | 2025-04-01 | マサチューセッツ インスティテュート オブ テクノロジー | キメラ抗原受容体ｔ細胞治療のための組成物およびその使用 |
| SG11202003415XA (en) | 2017-10-18 | 2020-05-28 | Novartis Ag | Compositions and methods for selective protein degradation |
| SG11202005307RA (en) * | 2017-12-14 | 2020-07-29 | Bluebird Bio Inc | Nkg2d daric receptors |
| KR20220066413A (ko) | 2017-12-14 | 2022-05-24 | 프로디자인 소닉스, 인크. | 음향 트랜스듀서 구동기 및 제어기 |
| KR20200110326A (ko) | 2017-12-14 | 2020-09-23 | 블루버드 바이오, 인코포레이티드. | Daric 인터류킨 수용체 |
| EP3502130A1 (en) | 2017-12-20 | 2019-06-26 | St. Anna Kinderkrebsforschung | Ligand regulated protein-protein interaction system |
| KR20250128387A (ko) | 2017-12-20 | 2025-08-27 | 세인트 안나 킨더크렙스포르슝 | 리간드 조절 단백질-단백질 상호작용 시스템 |
| JP7360174B2 (ja) | 2018-02-09 | 2023-10-12 | ナショナル ユニヴァーシティー オブ シンガポール | ナチュラルキラー細胞免疫療法における活性化キメラ受容体及びその使用 |
| US20230183313A1 (en) | 2018-02-11 | 2023-06-15 | Jiangsu Hengrui Medicine Co., Ltd. | Isolated chimeric antigen receptor, modified t cell comprising same and use thereof |
| JP7334985B2 (ja) | 2018-04-02 | 2023-08-29 | ナショナル ユニヴァーシティー オブ シンガポール | 免疫細胞で発現される膜結合抗サイトカイン非シグナル伝達バインダーによるヒトサイトカインの中和 |
| SG11202010233XA (en) * | 2018-04-27 | 2020-11-27 | Crispr Therapeutics Ag | Anti-bcma car-t-cells for plasma cell depletion |
| GB201813178D0 (en) * | 2018-08-13 | 2018-09-26 | Autolus Ltd | Cell |
| AU2019330347B2 (en) | 2018-08-29 | 2025-07-24 | National University Of Singapore | A method to specifically stimulate survival and expansion of genetically-modified immune cells |
| CA3113618A1 (en) | 2018-09-28 | 2020-04-02 | Massachusetts Institute Of Technology | Collagen-localized immunomodulatory molecules and methods thereof |
| EP3861024A4 (en) * | 2018-10-03 | 2022-12-21 | University of Pittsburgh - of the Commonwealth System of Higher Education | COVALENT ADAPTOR-SYNNOTCH AND CHIMERIC ANTIGEN RECEPTORS (CARS) FOR PROGRAMMABLE ANTIGEN TARGETING |
| CN113164576A (zh) * | 2018-10-05 | 2021-07-23 | 圣安娜儿童癌症研究中心 | 嵌合抗原受体(car)组 |
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| US8530636B2 (en) * | 2008-05-07 | 2013-09-10 | The Board Of Trustees Of The Leland Stanford Junior University | Method for regulating protein function in cells in vivo using synthetic small molecules |
| PT3300745T (pt) | 2013-02-15 | 2019-11-27 | Univ California | Recetor de antigénio quimérico e métodos de utilização do mesmo |
| EP3087101B1 (en) * | 2013-12-20 | 2024-06-05 | Novartis AG | Regulatable chimeric antigen receptor |
| WO2015142661A1 (en) | 2014-03-15 | 2015-09-24 | Novartis Ag | Regulatable chimeric antigen receptor |
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| RU2018109426A3 (enExample) | 2020-02-28 |
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