RU2018107727A3 - - Google Patents

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Publication number
RU2018107727A3
RU2018107727A3 RU2018107727A RU2018107727A RU2018107727A3 RU 2018107727 A3 RU2018107727 A3 RU 2018107727A3 RU 2018107727 A RU2018107727 A RU 2018107727A RU 2018107727 A RU2018107727 A RU 2018107727A RU 2018107727 A3 RU2018107727 A3 RU 2018107727A3
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RU
Russia
Application number
RU2018107727A
Other languages
Russian (ru)
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RU2018107727A (ru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of RU2018107727A publication Critical patent/RU2018107727A/ru
Publication of RU2018107727A3 publication Critical patent/RU2018107727A3/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Immunology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
RU2018107727A 2015-08-25 2016-08-24 Новые производные инсулина и их медицинские применения RU2018107727A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15182282.2 2015-08-25
EP15182282 2015-08-25
PCT/EP2016/069972 WO2017032798A1 (fr) 2015-08-25 2016-08-24 Nouveaux dérivés d'insuline et leurs utilisations médicales

Publications (2)

Publication Number Publication Date
RU2018107727A RU2018107727A (ru) 2019-10-01
RU2018107727A3 true RU2018107727A3 (fr) 2019-11-28

Family

ID=54007591

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2018107727A RU2018107727A (ru) 2015-08-25 2016-08-24 Новые производные инсулина и их медицинские применения

Country Status (15)

Country Link
US (1) US11352406B2 (fr)
EP (1) EP3341403B1 (fr)
JP (2) JP2018531900A (fr)
KR (1) KR20180038049A (fr)
CN (1) CN108026157B (fr)
AR (1) AR106364A1 (fr)
AU (1) AU2016311283B2 (fr)
BR (1) BR112018002416A2 (fr)
CA (1) CA2996455A1 (fr)
ES (1) ES2908373T3 (fr)
IL (1) IL257173A (fr)
MX (1) MX2018002223A (fr)
RU (1) RU2018107727A (fr)
TW (1) TW201717998A (fr)
WO (1) WO2017032798A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018531900A (ja) 2015-08-25 2018-11-01 ノヴォ ノルディスク アー／エス 新規インスリン誘導体及びその医学的使用
EP3668892A1 (fr) * 2017-08-17 2020-06-24 Novo Nordisk A/S Nouveaux analogues d'insuline acylés et leurs utilisations
US11649269B2 (en) 2018-10-05 2023-05-16 Novo Nordisk A/S Bifunctional compounds comprising insulin peptides and EGF(A) peptides
TW202112397A (zh) 2019-03-29 2021-04-01 丹麥商諾佛．儂迪克股份有限公司 葡萄糖敏感型胰島素衍生物
MX2022007034A (es) 2019-12-10 2022-06-23 Sanofi Sa Un metodo para formar un conjugado de una sulfonamida y un polipeptido.
BR112022009510A2 (pt) 2019-12-11 2022-08-16 Novo Nordisk As Análogo de insulina, composição farmacêutica, e, método de tratamento, prevenção ou alívio de uma doença ou distúrbio ou condição
CN118420744A (zh) * 2019-12-30 2024-08-02 甘李药业股份有限公司 胰岛素衍生物
KR20240013778A (ko) * 2021-05-24 2024-01-30 선샤인 레이크 파르마 컴퍼니 리미티드 신규한 아실화된 인슐린 유사체

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH25772A (en) 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation
DK105489D0 (da) 1989-03-03 1989-03-03 Novo Nordisk As Polypeptid
AU641721B2 (en) * 1989-12-21 1993-09-30 Novo Nordisk A/S Insulin preparations containing nicotinic acid or nicotinamide
KR100310122B1 (ko) 1993-09-17 2002-04-24 한센 핀 베네드, 안네 제헤르, 웨이콥 마리안느 아실화된인슐린
ZA954983B (en) 1994-06-17 1996-02-14 Novo Nordisk As N-terminally extended proteins expressed in yeast
US6500645B1 (en) 1994-06-17 2002-12-31 Novo Nordisk A/S N-terminally extended proteins expressed in yeast
US5922678A (en) 1996-06-28 1999-07-13 Eli Lilly And Company Methods for treating diabetes
EP0946735B1 (fr) 1996-12-20 2006-02-08 Novo Nordisk A/S Proteines a extension d'extremite n-terminal exprimees dans la levure
EP1627642A3 (fr) 1997-03-20 2006-04-19 Novo Nordisk A/S Cristaux d'insuline depourvus de zinc et utiles dans des compositions pour les voies respiratoires
PE123799A1 (es) 1997-10-24 1999-12-13 Lilly Co Eli Composiciones insolubles de insulina
DE10114178A1 (de) 2001-03-23 2002-10-10 Aventis Pharma Gmbh Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
US7193035B2 (en) * 2002-10-29 2007-03-20 Sanofi-Aventis Deutschland Gmbh Crystals of insulin analogs and processes for their preparation
ATE517119T1 (de) 2003-12-03 2011-08-15 Novo Nordisk As Einzelketteninsulin
JP2008533100A (ja) 2005-03-18 2008-08-21 ノボ ノルディスク アクティーゼルスカブ Ｐｅｇ化された単鎖インスリン
ATE557037T1 (de) 2006-02-27 2012-05-15 Novo Nordisk As Insulin derivate
JP2009530243A (ja) 2006-03-13 2009-08-27 ノボ・ノルデイスク・エー／エス アシル化単鎖インスリン
RU2352113C1 (ru) 2007-06-18 2009-04-20 Владимир Яковлевич Этин Ловушка для эктопаразитов
ITRG20070003A1 (it) 2007-07-17 2009-01-18 Salvatore Lucifora Metodo e sistema informatico per analizzare le prestazioni e dimensionare una cella underlay/overlay di un sistema di telecomunicazione cellulare
EP2178909B1 (fr) 2007-08-13 2015-10-21 Novo Nordisk A/S Analogues de l'insuline à action rapide
CN101784562B (zh) * 2007-08-15 2016-07-13 诺沃-诺迪斯克有限公司 具有酰基和亚烷基二醇部分的胰岛素类似物
WO2009022006A1 (fr) 2007-08-15 2009-02-19 Novo Nordisk A/S Insulines avec une fraction acyle comprenant des unités répétitives d'alkylène glycol contenant des acides aminés
ES2618073T3 (es) 2008-03-14 2017-06-20 Novo Nordisk A/S Análogos de insulina estabilizados frente a proteasas
EP2910571B1 (fr) 2008-03-18 2016-10-05 Novo Nordisk A/S Analogues de l'insuline acylés, stabilisés à la protéase
JP5818681B2 (ja) 2008-04-01 2015-11-18 ノボ・ノルデイスク・エー／エス インスリンアルブミンコンジュゲート
WO2011000823A1 (fr) 2009-06-30 2011-01-06 Novo Nordisk A/S Dérivés de l'insuline
EP2496213B1 (fr) 2009-11-02 2015-08-12 Novo Nordisk A/S Solution pharmaceutique d'insuline acylée et d'albumine liée de façon non covalente
JP5973427B2 (ja) 2010-06-23 2016-08-23 ノヴォ ノルディスク アー／エス 追加のジスルフィド結合を含有するインスリン類似体
JP2013541500A (ja) 2010-07-28 2013-11-14 スマートセルズ・インコーポレイテツド 組換えレクチン、結合部位修飾レクチンおよびそれらの用途
EP2627670A2 (fr) 2010-10-15 2013-08-21 Novo Nordisk A/S Nouveaux dérivés d'insuline à extrémité n modifiée
WO2012171994A1 (fr) 2011-06-15 2012-12-20 Novo Nordisk A/S Insulines à substitutions multiples
US9908925B2 (en) 2011-10-27 2018-03-06 Case Western Reserve University Ultra-concentrated rapid-acting insulin analogue formulations
WO2013086927A1 (fr) 2011-12-15 2013-06-20 上海恒瑞医药有限公司 Analogue d'insuline humaine et son dérivé acylé
JP6538645B2 (ja) 2013-03-14 2019-07-03 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションＩｎｄｉａｎａ Ｕｎｉｖｅｒｓｉｔｙ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｔｅｃｈｎｏｌｏｇｙ Ｃｏｒｐｏｒａｔｉｏｎ インスリン‐インクレチン複合物
MX366852B (es) 2013-10-04 2019-07-25 Merck Sharp & Dohme Conjugados de insulina sensibles a glucosa.
AR099569A1 (es) 2014-02-28 2016-08-03 Novo Nordisk As Derivados de insulina y los usos médicos de estos
EP3341401A1 (fr) 2015-08-25 2018-07-04 Novo Nordisk A/S Nouveaux dérivés de l'insuline et leurs utilisations médicales
JP2018531900A (ja) 2015-08-25 2018-11-01 ノヴォ ノルディスク アー／エス 新規インスリン誘導体及びその医学的使用
CN105440125B (zh) 2015-11-25 2019-09-24 华润昂德生物药业有限公司 地特胰岛素或其类似物的制备方法
WO2019125879A2 (fr) 2017-12-18 2019-06-27 Merck Sharp & Dohme Corp. Systèmes à base de conjugués pour l'administration contrôlée d'insuline
BR112022009510A2 (pt) 2019-12-11 2022-08-16 Novo Nordisk As Análogo de insulina, composição farmacêutica, e, método de tratamento, prevenção ou alívio de uma doença ou distúrbio ou condição

Also Published As

Publication number Publication date
TW201717998A (zh) 2017-06-01
AU2016311283A1 (en) 2018-02-15
EP3341403B1 (fr) 2022-01-05
WO2017032798A1 (fr) 2017-03-02
ES2908373T3 (es) 2022-04-28
US20180305431A1 (en) 2018-10-25
BR112018002416A2 (pt) 2018-09-18
AR106364A1 (es) 2018-01-10
IL257173A (en) 2018-06-28
MX2018002223A (es) 2018-03-23
RU2018107727A (ru) 2019-10-01
AU2016311283B2 (en) 2020-10-08
CA2996455A1 (fr) 2017-03-02
US11352406B2 (en) 2022-06-07
JP2021177779A (ja) 2021-11-18
KR20180038049A (ko) 2018-04-13
CN108026157A (zh) 2018-05-11
EP3341403A1 (fr) 2018-07-04
CN108026157B (zh) 2022-11-25
JP2018531900A (ja) 2018-11-01

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Legal Events

Date Code Title Description
FA91 Application withdrawn (on applicant's request)

Effective date: 20201230