RU2016139978A3 - - Google Patents

Download PDF

Info

Publication number
RU2016139978A3
RU2016139978A3 RU2016139978A RU2016139978A RU2016139978A3 RU 2016139978 A3 RU2016139978 A3 RU 2016139978A3 RU 2016139978 A RU2016139978 A RU 2016139978A RU 2016139978 A RU2016139978 A RU 2016139978A RU 2016139978 A3 RU2016139978 A3 RU 2016139978A3
Authority
RU
Russia
Application number
RU2016139978A
Other languages
Russian (ru)
Other versions
RU2740190C2 (ru
RU2016139978A (ru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB201404301A external-priority patent/GB201404301D0/en
Priority claimed from GB201421019A external-priority patent/GB201421019D0/en
Application filed filed Critical
Publication of RU2016139978A publication Critical patent/RU2016139978A/ru
Publication of RU2016139978A3 publication Critical patent/RU2016139978A3/ru
Application granted granted Critical
Publication of RU2740190C2 publication Critical patent/RU2740190C2/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C07K7/62—Polymyxins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU2016139978A 2014-03-11 2015-03-11 Производные полимиксина и их применение в комбинированной терапии совместно с различными антибиотиками RU2740190C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB201404301A GB201404301D0 (en) 2014-03-11 2014-03-11 Compounds and combinations
GB1404301.2 2014-03-11
GB1421019.9 2014-11-26
GB201421019A GB201421019D0 (en) 2014-11-26 2014-11-26 Compounds
PCT/EP2015/055046 WO2015135976A1 (en) 2014-03-11 2015-03-11 Polymyxin derivatives and their use in combination therapy together with different antibiotics

Publications (3)

Publication Number Publication Date
RU2016139978A RU2016139978A (ru) 2018-04-13
RU2016139978A3 true RU2016139978A3 (enExample) 2018-10-17
RU2740190C2 RU2740190C2 (ru) 2021-01-12

Family

ID=52823596

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2016139978A RU2740190C2 (ru) 2014-03-11 2015-03-11 Производные полимиксина и их применение в комбинированной терапии совместно с различными антибиотиками

Country Status (21)

Country Link
US (3) US20170073373A1 (enExample)
EP (1) EP3116897B1 (enExample)
JP (1) JP6785659B2 (enExample)
KR (2) KR20160135739A (enExample)
CN (1) CN106232617B (enExample)
AU (1) AU2015228898B2 (enExample)
CA (1) CA2940455C (enExample)
CY (1) CY1125175T1 (enExample)
DK (1) DK3116897T3 (enExample)
ES (1) ES2910072T3 (enExample)
HR (1) HRP20220387T1 (enExample)
IL (1) IL247243B (enExample)
LT (1) LT3116897T (enExample)
MX (1) MX359104B (enExample)
PL (1) PL3116897T3 (enExample)
PT (1) PT3116897T (enExample)
RS (1) RS63138B1 (enExample)
RU (1) RU2740190C2 (enExample)
SI (1) SI3116897T1 (enExample)
TW (1) TWI709575B (enExample)
WO (1) WO2015135976A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX355217B (es) * 2011-11-18 2018-04-10 New Pharma Licence Holdings Ltd Derivados de polimixina.
US10047126B2 (en) 2014-04-01 2018-08-14 Monash University Polymyxin derivatives as antimicrobial compounds
CN107108699A (zh) 2014-11-26 2017-08-29 新药物许可控股有限公司 化合物
EP3233889B1 (en) 2014-12-16 2022-07-06 Shanghai MicuRx Pharmaceutical Co., Ltd. Antimicrobial polymyxins for treatment of bacterial infections
CN105030744B (zh) * 2015-07-09 2019-04-19 广州英赛特生物技术有限公司 取代苯胍衍生物作为多粘菌素类抗生素增效剂的应用
JP7367950B2 (ja) * 2015-09-29 2023-10-24 モナッシュ ユニバーシティ 抗菌性ポリミキシン誘導体化合物
JP6744622B2 (ja) * 2016-06-16 2020-08-19 学校法人上智学院 ピペリジン化合物の製造方法
WO2019084628A1 (en) 2017-11-02 2019-05-09 The University Of Queensland Peptide antibiotics
DK3810633T3 (da) 2018-06-25 2024-01-15 Spero Therapeutics Inc Forbindelser
CN111690040A (zh) * 2019-03-12 2020-09-22 上海来益生物药物研究开发中心有限责任公司 多粘菌素衍生物、其制备方法和应用
WO2021150792A1 (en) 2020-01-21 2021-07-29 Micurx Pharmaceuticals, Inc. Novel compounds and composition for targeted therapy of kidney-associated cancers
TW202233649A (zh) 2020-11-06 2022-09-01 美商斯佩羅治療學股份有限公司 化合物
CN116847735B (zh) * 2021-02-02 2026-02-03 韩国生命工学研究院 含有联苯基衍生物化合物作为有效成分的抗菌佐剂及其用途
CN120574287B (zh) * 2025-06-10 2026-07-03 中国药科大学 一种抗菌肽、组合物及应用
CN120699105B (zh) * 2025-08-19 2025-11-21 中国药科大学 一种氘代抗菌肽及其组合物和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060004185A1 (en) * 2004-07-01 2006-01-05 Leese Richard A Peptide antibiotics and peptide intermediates for their prepartion
BRPI0715095B8 (pt) * 2006-08-11 2021-05-25 Northern Antibiotics Oy derivado de polimixina da fórmula geral (i); produto de combinação; composição farmacêutica; método para se sensibilizar bactérias gram-negativas a um agente antibacteriano; método para o desenvolvimento de antibióticos; método para a redução da toxicidade de polimixinas, octapeptinas naturais e seus derivados durante a aplicação das mesmas no tratamento de infecções em um indivíduo; método para melhorar as propriedades farmacocinéticas, de polimixinas, octapeptinas naturais e seus derivados; método para a sensibilização de bactérias gram-negativas clinicamente importantes a um complemento de mecanismo de defesa presente no soro; uso de um derivado; e processo para a preparação de um derivado de polimixina da fórmula (i).
WO2010075416A1 (en) * 2008-12-23 2010-07-01 Biosource Pharm, Inc. Antibiotic compositions for the treatment of gram negative infections
CN101851270A (zh) * 2009-04-03 2010-10-06 梁浩 一种多粘菌素衍生物及其制备方法
US8415307B1 (en) * 2010-06-23 2013-04-09 Biosource Pharm, Inc. Antibiotic compositions for the treatment of gram negative infections
WO2012168820A1 (en) * 2011-06-08 2012-12-13 Pfizer Inc. Polymyxin derivatives useful as antibacterial agents
MX355217B (es) * 2011-11-18 2018-04-10 New Pharma Licence Holdings Ltd Derivados de polimixina.
HUE059544T2 (hu) * 2013-05-22 2022-11-28 Spero Therapeutics Inc Polimixin-származékok és ezek alkalmazása kombinációs terápiában különbözõ antibiotikumokkal

Also Published As

Publication number Publication date
PL3116897T3 (pl) 2022-05-30
KR20160135739A (ko) 2016-11-28
MX359104B (es) 2018-09-14
IL247243B (en) 2020-04-30
SI3116897T1 (sl) 2022-06-30
RS63138B1 (sr) 2022-05-31
EP3116897A1 (en) 2017-01-18
JP6785659B2 (ja) 2020-11-18
ES2910072T3 (es) 2022-05-11
CA2940455A1 (en) 2015-09-17
HRP20220387T1 (hr) 2022-05-27
CN106232617A (zh) 2016-12-14
IL247243A0 (en) 2016-09-29
AU2015228898A1 (en) 2016-10-20
US20230322858A1 (en) 2023-10-12
JP2017510570A (ja) 2017-04-13
AU2015228898B2 (en) 2018-11-15
MX2016011682A (es) 2017-04-27
US20170073373A1 (en) 2017-03-16
PT3116897T (pt) 2022-04-07
EP3116897B1 (en) 2022-03-02
DK3116897T3 (da) 2022-03-28
TW201617362A (zh) 2016-05-16
CN106232617B (zh) 2022-06-24
US20210221848A1 (en) 2021-07-22
RU2740190C2 (ru) 2021-01-12
KR20230152779A (ko) 2023-11-03
CY1125175T1 (el) 2024-12-13
LT3116897T (lt) 2022-05-10
CA2940455C (en) 2023-03-21
TWI709575B (zh) 2020-11-11
WO2015135976A1 (en) 2015-09-17
RU2016139978A (ru) 2018-04-13

Similar Documents

Publication Publication Date Title
BR112016017664A2 (enExample)
BR112016017979A2 (enExample)
BR112016015519A2 (enExample)
BR112016015890A2 (enExample)
BR112016003131A2 (enExample)
BR112016016490A2 (enExample)
BR112016016546A2 (enExample)
BR112016014949A2 (enExample)
BR112016018264A2 (enExample)
BR112016017103A2 (enExample)
BR112016017031A2 (enExample)
BR112016016924A2 (enExample)
BR112015027867A2 (enExample)
BR112016016421A2 (enExample)
BR112016030815A2 (enExample)
BR112016016106A2 (enExample)
BR112016012568A2 (enExample)
BR112016016558A2 (enExample)
BR112016015798A2 (enExample)
BR112016017960A2 (enExample)
BR112016015915A2 (enExample)
BR112016018252A2 (enExample)
BR112016016468A2 (enExample)
BR112016017356A2 (enExample)
BR112016016459A2 (enExample)

Legal Events

Date Code Title Description
HZ9A Changing address for correspondence with an applicant