LT3116897T - Polimiksino dariniai ir jų panaudojimas kompleksinėje terapijoje kartu su skirtingais antibiotikais - Google Patents

Polimiksino dariniai ir jų panaudojimas kompleksinėje terapijoje kartu su skirtingais antibiotikais

Info

Publication number
LT3116897T
LT3116897T LTEPPCT/EP2015/055046T LT15055046T LT3116897T LT 3116897 T LT3116897 T LT 3116897T LT 15055046 T LT15055046 T LT 15055046T LT 3116897 T LT3116897 T LT 3116897T
Authority
LT
Lithuania
Prior art keywords
polymixin
derivatives
different antibiotics
complex therapy
therapy
Prior art date
Application number
LTEPPCT/EP2015/055046T
Other languages
English (en)
Lithuanian (lt)
Inventor
Pamela Brown
Michael Dawson
Mona SIMONOVIC
Steven Boakes
Esther DUPERCHY
Steven James Stanway
Antoinette Wilson
Stephen Frederick Moss
Original Assignee
Spero Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB201404301A external-priority patent/GB201404301D0/en
Priority claimed from GB201421019A external-priority patent/GB201421019D0/en
Application filed by Spero Therapeutics, Inc. filed Critical Spero Therapeutics, Inc.
Publication of LT3116897T publication Critical patent/LT3116897T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C07K7/62Polymyxins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
LTEPPCT/EP2015/055046T 2014-03-11 2015-03-11 Polimiksino dariniai ir jų panaudojimas kompleksinėje terapijoje kartu su skirtingais antibiotikais LT3116897T (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB201404301A GB201404301D0 (en) 2014-03-11 2014-03-11 Compounds and combinations
GB201421019A GB201421019D0 (en) 2014-11-26 2014-11-26 Compounds
PCT/EP2015/055046 WO2015135976A1 (en) 2014-03-11 2015-03-11 Polymyxin derivatives and their use in combination therapy together with different antibiotics

Publications (1)

Publication Number Publication Date
LT3116897T true LT3116897T (lt) 2022-05-10

Family

ID=52823596

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/EP2015/055046T LT3116897T (lt) 2014-03-11 2015-03-11 Polimiksino dariniai ir jų panaudojimas kompleksinėje terapijoje kartu su skirtingais antibiotikais

Country Status (21)

Country Link
US (3) US20170073373A1 (enExample)
EP (1) EP3116897B1 (enExample)
JP (1) JP6785659B2 (enExample)
KR (2) KR20160135739A (enExample)
CN (1) CN106232617B (enExample)
AU (1) AU2015228898B2 (enExample)
CA (1) CA2940455C (enExample)
CY (1) CY1125175T1 (enExample)
DK (1) DK3116897T3 (enExample)
ES (1) ES2910072T3 (enExample)
HR (1) HRP20220387T1 (enExample)
IL (1) IL247243B (enExample)
LT (1) LT3116897T (enExample)
MX (1) MX359104B (enExample)
PL (1) PL3116897T3 (enExample)
PT (1) PT3116897T (enExample)
RS (1) RS63138B1 (enExample)
RU (1) RU2740190C2 (enExample)
SI (1) SI3116897T1 (enExample)
TW (1) TWI709575B (enExample)
WO (1) WO2015135976A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112014012016A2 (pt) * 2011-11-18 2017-05-16 Cantab Anti-Infectives Ltd compostos
US10047126B2 (en) 2014-04-01 2018-08-14 Monash University Polymyxin derivatives as antimicrobial compounds
WO2016083531A1 (en) 2014-11-26 2016-06-02 New Pharma Licence Holdings Limited Compounds
EP3233889B1 (en) 2014-12-16 2022-07-06 Shanghai MicuRx Pharmaceutical Co., Ltd. Antimicrobial polymyxins for treatment of bacterial infections
CN105030744B (zh) * 2015-07-09 2019-04-19 广州英赛特生物技术有限公司 取代苯胍衍生物作为多粘菌素类抗生素增效剂的应用
CN108350034B (zh) * 2015-09-29 2022-03-11 莫纳什大学 抗微生物的多黏菌素衍生的化合物
JP6744622B2 (ja) * 2016-06-16 2020-08-19 学校法人上智学院 ピペリジン化合物の製造方法
WO2019084628A1 (en) 2017-11-02 2019-05-09 The University Of Queensland Peptide antibiotics
CN112789287B (zh) 2018-06-25 2024-06-21 云顶新耀医药科技有限公司 化合物
CN111690040A (zh) * 2019-03-12 2020-09-22 上海来益生物药物研究开发中心有限责任公司 多粘菌素衍生物、其制备方法和应用
WO2021150792A1 (en) 2020-01-21 2021-07-29 Micurx Pharmaceuticals, Inc. Novel compounds and composition for targeted therapy of kidney-associated cancers
WO2022098950A1 (en) 2020-11-06 2022-05-12 Spero Therapeutics, Inc. Compounds
CN120699105B (zh) * 2025-08-19 2025-11-21 中国药科大学 一种氘代抗菌肽及其组合物和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060004185A1 (en) * 2004-07-01 2006-01-05 Leese Richard A Peptide antibiotics and peptide intermediates for their prepartion
KR20150008198A (ko) * 2006-08-11 2015-01-21 노던 안티바이오틱스 리미티드 폴리믹신 유도체들 및 이들의 용도
AR074874A1 (es) * 2008-12-23 2011-02-16 Biosource Pharm Inc Composiciones antibioticas para el tratamiento de infecciones gram negativas. metodo. uso. compuesto.
CN101851270A (zh) * 2009-04-03 2010-10-06 梁浩 一种多粘菌素衍生物及其制备方法
US8415307B1 (en) * 2010-06-23 2013-04-09 Biosource Pharm, Inc. Antibiotic compositions for the treatment of gram negative infections
WO2012168820A1 (en) * 2011-06-08 2012-12-13 Pfizer Inc. Polymyxin derivatives useful as antibacterial agents
BR112014012016A2 (pt) * 2011-11-18 2017-05-16 Cantab Anti-Infectives Ltd compostos
BR112015029309A2 (pt) * 2013-05-22 2017-07-25 New Pharma Licence Holdings Ltd derivados de polimixina e seu uso em terapia de combinação junto com antibióticos diferentes

Also Published As

Publication number Publication date
TWI709575B (zh) 2020-11-11
HRP20220387T1 (hr) 2022-05-27
US20230322858A1 (en) 2023-10-12
JP6785659B2 (ja) 2020-11-18
RS63138B1 (sr) 2022-05-31
WO2015135976A1 (en) 2015-09-17
RU2016139978A3 (enExample) 2018-10-17
SI3116897T1 (sl) 2022-06-30
PT3116897T (pt) 2022-04-07
DK3116897T3 (da) 2022-03-28
IL247243A0 (en) 2016-09-29
CA2940455A1 (en) 2015-09-17
CY1125175T1 (el) 2024-12-13
AU2015228898A1 (en) 2016-10-20
AU2015228898B2 (en) 2018-11-15
CN106232617B (zh) 2022-06-24
CA2940455C (en) 2023-03-21
EP3116897A1 (en) 2017-01-18
KR20160135739A (ko) 2016-11-28
MX359104B (es) 2018-09-14
JP2017510570A (ja) 2017-04-13
CN106232617A (zh) 2016-12-14
ES2910072T3 (es) 2022-05-11
IL247243B (en) 2020-04-30
RU2016139978A (ru) 2018-04-13
US20170073373A1 (en) 2017-03-16
US20210221848A1 (en) 2021-07-22
EP3116897B1 (en) 2022-03-02
TW201617362A (zh) 2016-05-16
KR20230152779A (ko) 2023-11-03
MX2016011682A (es) 2017-04-27
PL3116897T3 (pl) 2022-05-30
RU2740190C2 (ru) 2021-01-12

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