RU2016109368A - Мукозальная вакцинная композиция - Google Patents

Мукозальная вакцинная композиция Download PDF

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Publication number
RU2016109368A
RU2016109368A RU2016109368A RU2016109368A RU2016109368A RU 2016109368 A RU2016109368 A RU 2016109368A RU 2016109368 A RU2016109368 A RU 2016109368A RU 2016109368 A RU2016109368 A RU 2016109368A RU 2016109368 A RU2016109368 A RU 2016109368A
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Russia
Prior art keywords
mucous membrane
vaccine composition
mucosal vaccine
solid preparation
composition according
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RU2016109368A
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English (en)
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RU2016109368A3 (ru
Inventor
Масахиро ФУКАСАКА
Мицухико ХОРИ
Кацуюки ОКУБО
Дайсуке АСАРИ
Аримити ОКАДЗАКИ
Еидзи КИЙОТОХ
Киохей МАЦУСИТА
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Нитто Денко Корпорейшн
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Publication of RU2016109368A publication Critical patent/RU2016109368A/ru
Publication of RU2016109368A3 publication Critical patent/RU2016109368A3/ru

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Claims (7)

1. Мукозальная вакцинная композиция, предназначенная для введения по меньшей мере в одну слизистую оболочку, выбранную из группы, состоящей из слизистой оболочки полости рта, слизистой оболочки глаза, слизистой оболочки уха, слизистой оболочки половых органов, слизистой оболочки гортани, слизистой оболочки дыхательных путей, слизистой оболочки бронхов, слизистой оболочки легких, слизистой оболочки желудка, слизистой оболочки кишечника и слизистой оболочки прямой кишки человека или животного, где мукозальная вакцинная композиция содержит:
по меньшей мере один антиген и
липополисахарид, получаемый по меньшей мере из одной грамотрицательной бактерии, выбранной из группы, состоящей из Serratia, Leclercia, Rahnella, Acidicaldus, Acidiphilium, Acidisphaera, Acidocella, Acidomonas, Asaia, Belnapia, Craurococcus, Gluconacetobacter, Gluconobacter, Kozakia, Leahibacter, Muricoccus, Neoasaia, Oleomonas, Paracraurococcus, Rhodopila, Roseococcus, Rubritepida, Saccharibacter, Stella, Swaminathania, Teichococcus, Zavarzinia, Pseudomonas, Achromobacter, Bacillus, Methanoculleus, Methanosarcina, Clostridium, Micrococcus, Flavobacterium, Pantoea, Acetobacter, Zymomonas, Xanthomonas и Enterobacter, или его соль в качестве адъюванта.
2. Мукозальная вакцинная композиция по п. 1, которая представляет собой жидкий препарат, аэрозоль, полутвердый препарат или твердый препарат, где указанный полутвердый препарат и указанный твердый препарат растворяются жидкостью организма и/или при температуре тела.
3. Мукозальная вакцинная композиция по п. 2, которая представляет собой твердый препарат, который растворяется жидкостью организма и/или при температуре тела.
4. Мукозальная вакцинная композиция по пп. 1, 2 или 3, предназначенная для использования для индукции гуморального иммунитета.
5. Мукозальная вакцинная композиция по пп. 1, 2, 3 или 4, где антиген представляет собой антиген, получаемый из возбудителя инфекционного заболевания, или ракового антигена.
RU2016109368A 2013-10-03 2014-10-02 Мукозальная вакцинная композиция RU2016109368A (ru)

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