RU2015144057A3 - - Google Patents
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- RU2015144057A3 RU2015144057A3 RU2015144057A RU2015144057A RU2015144057A3 RU 2015144057 A3 RU2015144057 A3 RU 2015144057A3 RU 2015144057 A RU2015144057 A RU 2015144057A RU 2015144057 A RU2015144057 A RU 2015144057A RU 2015144057 A3 RU2015144057 A3 RU 2015144057A3
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361787818P | 2013-03-15 | 2013-03-15 | |
| US61/787,818 | 2013-03-15 | ||
| PCT/US2014/030370 WO2014145578A1 (en) | 2013-03-15 | 2014-03-17 | Scalable manufacturing process to produce recombinant lentiviral vectors in serum-free suspension cell culture system |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2015144057A RU2015144057A (ru) | 2017-04-27 |
| RU2015144057A3 true RU2015144057A3 (enExample) | 2018-01-22 |
| RU2709678C2 RU2709678C2 (ru) | 2019-12-19 |
Family
ID=51538029
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015144057A RU2709678C2 (ru) | 2013-03-15 | 2014-03-17 | Масштабный производственный способ получения рекомбинантных лентивирусных векторов в системе культивирования клеток в бессывороточной суспензии |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20140323556A1 (enExample) |
| EP (1) | EP2970920B1 (enExample) |
| JP (1) | JP6480910B6 (enExample) |
| KR (1) | KR102200278B1 (enExample) |
| CN (2) | CN105378074A (enExample) |
| AU (1) | AU2014232879B2 (enExample) |
| BR (1) | BR112015022292A2 (enExample) |
| CA (1) | CA2904366C (enExample) |
| DK (1) | DK2970920T3 (enExample) |
| ES (1) | ES2681434T3 (enExample) |
| IL (1) | IL241058B (enExample) |
| MX (1) | MX364690B (enExample) |
| PT (1) | PT2970920T (enExample) |
| RU (1) | RU2709678C2 (enExample) |
| WO (1) | WO2014145578A1 (enExample) |
| ZA (1) | ZA201506478B (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11596652B2 (en) | 2015-02-18 | 2023-03-07 | Enlivex Therapeutics R&D Ltd | Early apoptotic cells for use in treating sepsis |
| US11497767B2 (en) | 2015-02-18 | 2022-11-15 | Enlivex Therapeutics R&D Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| US11512289B2 (en) | 2015-02-18 | 2022-11-29 | Enlivex Therapeutics Rdo Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| US11000548B2 (en) | 2015-02-18 | 2021-05-11 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| US11304976B2 (en) | 2015-02-18 | 2022-04-19 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| US11318163B2 (en) | 2015-02-18 | 2022-05-03 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| TWI547782B (zh) * | 2015-03-16 | 2016-09-01 | 智易科技股份有限公司 | 可擴充式製程系統與實現該系統的方法 |
| JP6803339B2 (ja) | 2015-04-21 | 2020-12-23 | エンリヴェックス セラピューティクス リミテッド | 治療用のプールされた血液アポトーシス細胞調製物及びそれらの使用 |
| EP3384015A4 (en) * | 2015-12-01 | 2019-05-29 | Spark Therapeutics, Inc. | SCALABLE PROCESS FOR THE PREPARATION OF A RECOMBINANT ADENO ASSOCIATED VIRAL VECTOR IN A SERUM-FREE SUSPENSION CELL CULTURE SYSTEM SUITABLE FOR THE CLINICAL APPLICATION |
| CN107043784A (zh) * | 2016-02-05 | 2017-08-15 | 上海吉凯基因化学技术有限公司 | 一种慢病毒载体的制备方法 |
| JP6884155B2 (ja) | 2016-02-18 | 2021-06-09 | エンリヴェックス セラピューティクス リミテッド | 癌治療のための併用免疫療法及びサイトカイン制御療法 |
| WO2017173043A1 (en) * | 2016-03-30 | 2017-10-05 | Spark Therapeutics, Inc. | Cell line for recombinant protein and/or viral vector production |
| EP3442688A4 (en) | 2016-04-12 | 2019-11-20 | Artemis Biosystems, Inc. | FILTRATION SYSTEMS FOR INFUSION |
| CN106497882A (zh) * | 2016-10-29 | 2017-03-15 | 复旦大学 | 同时过表达R‑spondin1和Noggin的细胞株及其构建方法和应用 |
| ES2975182T3 (es) * | 2017-03-06 | 2024-07-03 | Guangzhou Realbenefitspot Pharmaceutical Co Ltd | Métodos de producción y caracterización de vacunas víricas y composición de vacuna vírica |
| EP3420076B1 (en) | 2017-03-06 | 2024-02-21 | Guangzhou Realbenefitspot Pharmaceutical Co., Ltd. | Methods of producing and characterizing virus vaccine and virus vaccine composition |
| CN109251939A (zh) * | 2017-07-14 | 2019-01-22 | 孙搏 | Il-17g-197a慢病毒表达载体、其构建方法及慢病毒的包装测定方法 |
| WO2019147036A1 (ko) * | 2018-01-24 | 2019-08-01 | 주식회사 에스엘바이젠 | 뇌유래-신경영양인자를 발현하는 중간엽줄기세포 및 이의 용도 |
| CN110317832B (zh) * | 2018-03-28 | 2022-07-05 | 西比曼生物科技（香港）有限公司 | Gmp级规模化制备重组慢病毒载体的纯化制剂的方法 |
| CN111763238B (zh) * | 2019-04-02 | 2022-07-29 | 普莱柯生物工程股份有限公司 | 一种蛋白抗原的纯化方法、制备的蛋白抗原及其应用 |
| ES2965341T3 (es) | 2019-04-11 | 2024-04-12 | Regenxbio Inc | Métodos de cromatografía de exclusión por tamaño para la caracterización de composiciones de virus adenoasociados recombinantes |
| CN110054678B (zh) * | 2019-05-16 | 2023-04-18 | 中国医学科学院血液病医院（血液学研究所） | 一种膜结合型mFLT3LG蛋白及其应用 |
| AU2020325705B2 (en) * | 2019-08-05 | 2026-02-05 | Sartorius Polyplus | Compositions for transfecting a nucleic acid molecule into a cell comprising heterocyclic compounds grafted to a cationic polymer, and their applications |
| KR20220047635A (ko) | 2019-08-23 | 2022-04-18 | 론자 워커스빌 아이엔씨. | 렌티바이러스 벡터의 생산을 위한 방법 및 작제물 |
| CN110894494B (zh) * | 2019-11-22 | 2022-09-27 | 广西梧州制药（集团）股份有限公司 | 一种大规模高密度悬浮培养293细胞高产腺病毒的方法 |
| CN110938654A (zh) * | 2019-12-11 | 2020-03-31 | 和元生物技术（上海）股份有限公司 | 一种细胞转染试剂及其应用 |
| CN113122501B (zh) * | 2019-12-30 | 2023-06-16 | 重庆精准生物技术有限公司 | 适合大规模临床级病毒载体制备的培养基及其应用 |
| CA3194520A1 (en) * | 2020-06-11 | 2021-12-16 | 2Seventy Bio, Inc. | Methods for manufacturing viral vectors |
| CA3188923A1 (en) * | 2020-08-13 | 2022-02-17 | Michael Sean BURNHAM | Methods for producing clinical-grade lentiviral vector |
| CN112746076B (zh) * | 2020-12-28 | 2023-05-12 | 中吉智药(南京)生物技术有限公司 | 一种密码子优化的col7a1基因及慢病毒和应用 |
| WO2022143623A1 (zh) * | 2020-12-29 | 2022-07-07 | 江苏金斯瑞蓬勃生物科技有限公司 | 高分散性的hek293t细胞株及其筛选方法 |
| AR125468A1 (es) * | 2021-04-27 | 2023-07-19 | Novartis Ag | Sistema de producción de vectores virales |
| EP4373951A1 (en) * | 2021-07-19 | 2024-05-29 | 2seventy bio, Inc. | Vector manufacturing processes |
| CN113980916B (zh) * | 2021-09-27 | 2024-11-05 | 湖南丰晖生物科技有限公司 | 一种慢病毒的纯化方法 |
| US20240425880A1 (en) * | 2021-10-12 | 2024-12-26 | Jiangsu Genscript Probio Biotech Co., Ltd. | Hek293 cell line adapted to serum-free suspension culture and use thereof |
| CN114990077A (zh) * | 2022-08-01 | 2022-09-02 | 深圳市先康达生命科学有限公司 | 一种慢病毒包装与纯化方法 |
| CN116240241A (zh) * | 2022-12-30 | 2023-06-09 | 上海本导基因技术有限公司 | 重组慢病毒载体的纯化制备方法 |
| IN202321021121A (enExample) * | 2023-03-24 | 2024-04-19 | ||
| EP4694993A1 (en) * | 2023-04-12 | 2026-02-18 | Cytiva BioProcess R&D AB | A chromatography system, use thereof, and a method for separating enveloped or membranous biological particles |
| CN122012416A (zh) * | 2026-04-14 | 2026-05-12 | 山东丽山生物科技有限公司 | 一种提高慢病毒滴度的方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5869445A (en) * | 1993-03-17 | 1999-02-09 | University Of Washington | Methods for eliciting or enhancing reactivity to HER-2/neu protein |
| US20030157070A1 (en) * | 1994-12-30 | 2003-08-21 | Jolly Douglas J. | High efficiency ex vivo transduction of cells by high titer recombinant retroviral preparations |
| US6544769B1 (en) * | 1996-12-13 | 2003-04-08 | Schering Corporation | Compostions comprising viruses and methods for concentrating virus preparations |
| US6207455B1 (en) | 1997-05-01 | 2001-03-27 | Lung-Ji Chang | Lentiviral vectors |
| US5994136A (en) | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| US7575924B2 (en) * | 2000-11-13 | 2009-08-18 | Research Development Foundation | Methods and compositions relating to improved lentiviral vectors and their applications |
| WO2003039459A2 (en) * | 2001-11-05 | 2003-05-15 | Genvec, Inc. | Viral vector production methods and compositions |
| DE60327069D1 (de) * | 2002-04-30 | 2009-05-20 | Oncolytics Biotech Inc | Verbesserte reinigungsmethode für viren |
| AU2003272868A1 (en) * | 2003-10-15 | 2005-04-27 | Agtc Gene Technology Company Ltd. | Method for large-scale production, isolation, purification and the uses of multi-type recombinant adeno-associated virus vectors |
| WO2007004947A1 (en) * | 2005-07-06 | 2007-01-11 | Ge Healthcare Bio-Sciences Ab | Method of preparing a separation matrix |
| WO2008148304A1 (en) * | 2007-05-31 | 2008-12-11 | Xiamen University | Rna interference target for treating aids |
| EP2012122A1 (en) * | 2007-07-06 | 2009-01-07 | Medigene AG | Mutated parvovirus structural proteins as vaccines |
| WO2009153563A1 (en) * | 2008-06-18 | 2009-12-23 | Oxford Biomedica (Uk) Limited | Virus purification |
| CN102216450B (zh) * | 2008-09-24 | 2014-05-14 | 米迪缪尼有限公司 | 培养细胞、增殖和纯化病毒的方法 |
| JP5956331B2 (ja) | 2009-06-16 | 2016-07-27 | ジェンザイム・コーポレーション | 組換えａａｖベクターの改良された精製方法 |
| US20130052165A1 (en) * | 2010-01-12 | 2013-02-28 | Livnat Bangio | Methods of Producing Adenovirus Vectors and Viral Preparations Generated Thereby |
| WO2011097447A2 (en) * | 2010-02-04 | 2011-08-11 | Neurologix, Inc. | Production of recombinant virus |
-
2014
- 2014-03-17 PT PT147622492T patent/PT2970920T/pt unknown
- 2014-03-17 CN CN201480016236.2A patent/CN105378074A/zh active Pending
- 2014-03-17 JP JP2016503383A patent/JP6480910B6/ja active Active
- 2014-03-17 RU RU2015144057A patent/RU2709678C2/ru active
- 2014-03-17 EP EP14762249.2A patent/EP2970920B1/en active Active
- 2014-03-17 BR BR112015022292A patent/BR112015022292A2/pt not_active Application Discontinuation
- 2014-03-17 MX MX2015012450A patent/MX364690B/es active IP Right Grant
- 2014-03-17 WO PCT/US2014/030370 patent/WO2014145578A1/en not_active Ceased
- 2014-03-17 CA CA2904366A patent/CA2904366C/en active Active
- 2014-03-17 CN CN202410062902.1A patent/CN118256453A/zh active Pending
- 2014-03-17 AU AU2014232879A patent/AU2014232879B2/en active Active
- 2014-03-17 ES ES14762249.2T patent/ES2681434T3/es active Active
- 2014-03-17 DK DK14762249.2T patent/DK2970920T3/en active
- 2014-03-17 US US14/216,778 patent/US20140323556A1/en not_active Abandoned
- 2014-03-17 KR KR1020157029322A patent/KR102200278B1/ko active Active
-
2015
- 2015-09-02 IL IL241058A patent/IL241058B/en active IP Right Grant
- 2015-09-03 ZA ZA2015/06478A patent/ZA201506478B/en unknown
-
2017
- 2017-09-08 US US15/699,613 patent/US10994028B2/en active Active
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