RU2015141314A3 - - Google Patents

Download PDF

Info

Publication number
RU2015141314A3
RU2015141314A3 RU2015141314A RU2015141314A RU2015141314A3 RU 2015141314 A3 RU2015141314 A3 RU 2015141314A3 RU 2015141314 A RU2015141314 A RU 2015141314A RU 2015141314 A RU2015141314 A RU 2015141314A RU 2015141314 A3 RU2015141314 A3 RU 2015141314A3
Authority
RU
Russia
Application number
RU2015141314A
Other languages
Russian (ru)
Other versions
RU2015141314A (ru
RU2709780C2 (ru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40118825&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RU2015141314(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of RU2015141314A publication Critical patent/RU2015141314A/ru
Publication of RU2015141314A3 publication Critical patent/RU2015141314A3/ru
Application granted granted Critical
Publication of RU2709780C2 publication Critical patent/RU2709780C2/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/50Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/35Fat tissue; Adipocytes; Stromal cells; Connective tissues
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Transplantation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU2015141314A 2007-09-19 2008-09-02 Адгезивные клетки жировой ткани или плаценты и их использование в лечебных целях RU2709780C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96018407P 2007-09-19 2007-09-19
US60/960,184 2007-09-19

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
RU2010109698/15A Division RU2010109698A (ru) 2007-09-19 2008-09-02 Адгезивные клетки жировой ткани или плаценты и их использование в лечебных целях

Publications (3)

Publication Number Publication Date
RU2015141314A RU2015141314A (ru) 2018-12-26
RU2015141314A3 true RU2015141314A3 (OSRAM) 2019-03-14
RU2709780C2 RU2709780C2 (ru) 2019-12-20

Family

ID=40118825

Family Applications (2)

Application Number Title Priority Date Filing Date
RU2010109698/15A RU2010109698A (ru) 2007-09-19 2008-09-02 Адгезивные клетки жировой ткани или плаценты и их использование в лечебных целях
RU2015141314A RU2709780C2 (ru) 2007-09-19 2008-09-02 Адгезивные клетки жировой ткани или плаценты и их использование в лечебных целях

Family Applications Before (1)

Application Number Title Priority Date Filing Date
RU2010109698/15A RU2010109698A (ru) 2007-09-19 2008-09-02 Адгезивные клетки жировой ткани или плаценты и их использование в лечебных целях

Country Status (18)

Country Link
US (4) US8529888B2 (OSRAM)
EP (3) EP2591789B2 (OSRAM)
JP (5) JP2010539228A (OSRAM)
KR (4) KR20140107677A (OSRAM)
CN (2) CN107028981B (OSRAM)
AU (1) AU2008300185B2 (OSRAM)
BR (1) BRPI0815946B8 (OSRAM)
CA (1) CA2699664C (OSRAM)
ES (1) ES2392729T5 (OSRAM)
HR (1) HRP20120887T4 (OSRAM)
IL (4) IL204566A (OSRAM)
MX (1) MX2010003019A (OSRAM)
PL (1) PL2200622T5 (OSRAM)
PT (1) PT2200622E (OSRAM)
RU (2) RU2010109698A (OSRAM)
SI (1) SI2200622T2 (OSRAM)
WO (1) WO2009037690A1 (OSRAM)
ZA (1) ZA201001929B (OSRAM)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060045872A1 (en) 2004-08-25 2006-03-02 Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco Use of adipose tissue-derived stromal stem cells in treating fistula
WO2007039150A2 (en) 2005-09-23 2007-04-12 Cellerix, S.L. Cell populations having immunoregulatory activity, method for isolation and uses
US8182841B2 (en) 2005-09-27 2012-05-22 Tissue Tech, Inc. Amniotic membrane preparations and purified compositions and anti-inflammation methods
WO2011132087A1 (en) 2010-04-23 2011-10-27 Pluristem Ltd. Adherent stromal cells derived from plancentas of multiple donors and uses thereof
US12180549B2 (en) 2007-07-23 2024-12-31 The Chinese University Of Hong Kong Diagnosing fetal chromosomal aneuploidy using genomic sequencing
KR102222378B1 (ko) 2007-07-23 2021-03-04 더 차이니즈 유니버시티 오브 홍콩 핵산 서열 불균형의 결정
RU2010109698A (ru) 2007-09-19 2011-09-27 Плуристем Лтд. (Il) Адгезивные клетки жировой ткани или плаценты и их использование в лечебных целях
MX2010003217A (es) * 2007-09-26 2010-07-30 Celgene Cellular Therapeutics Celulas angiogenicas de perfundido de placenta humana.
CA2725637A1 (en) * 2008-05-27 2009-12-03 Pluristem Ltd. Methods of treating inflammatory colon diseases
CN105766891A (zh) 2008-08-20 2016-07-20 人类起源公司 改进的细胞组合物及制备所述组合物的方法
EP2334783B1 (en) * 2008-09-02 2016-06-22 Pluristem Ltd. Adherent cells from placenta tissue and use thereof in therapy
ES2749500T3 (es) 2008-11-19 2020-03-20 Celularity Inc Células adherentes derivadas del amnios
EP2806023B1 (en) 2009-11-30 2015-09-23 Pluristem Ltd. Adherent cells from placenta and use of same in disease treatment
EP2556145B1 (en) * 2010-04-07 2016-07-20 Anthrogenesis Corporation Angiogenesis using placental stem cells
AU2013203479B2 (en) * 2010-04-07 2016-05-19 Celularity Inc. Angiogenesis using placental stem cells
US9757419B2 (en) 2010-05-27 2017-09-12 Pluristem Ltd. Skeletal muscle regeneration using mesenchymal system cells
WO2012048276A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
WO2012092485A1 (en) 2010-12-31 2012-07-05 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory rna molecules
KR101835917B1 (ko) * 2011-03-22 2018-03-07 플루리스템 리미티드 방사선 또는 화학적 손상을 치료하는 방법들
WO2012140519A2 (en) 2011-04-15 2012-10-18 Pluristem Ltd. Methods and systems for harvesting cells
WO2012149486A1 (en) 2011-04-28 2012-11-01 Tissuetech, Inc. Methods of modulating bone remodeling
WO2012166844A2 (en) 2011-06-01 2012-12-06 Anthrogenesis Corporation Treatment of pain using placental stem cells
SG10201914092XA (en) 2011-06-06 2020-03-30 ReGenesys BVBA Expansion of stem cells in hollow fiber bioreactors
TW201311259A (zh) * 2011-07-15 2013-03-16 Anthrogenesis Corp 利用羊膜衍生附著性細胞治療輻射傷害
WO2013070734A1 (en) 2011-11-07 2013-05-16 Chaudhry Hina W Methods of cardiac repair
US9892230B2 (en) 2012-03-08 2018-02-13 The Chinese University Of Hong Kong Size-based analysis of fetal or tumor DNA fraction in plasma
AU2013311289B2 (en) 2012-09-04 2017-11-16 Pluristem Ltd. Methods for prevention and treatment of preeclampsia
CA2882108C (en) 2012-09-06 2016-01-05 Pluristem Ltd. Three dimensional devices for supporting monolayer cell growth and methods of culturing cells therewith
JP6545102B2 (ja) 2013-01-18 2019-07-17 ミメディクス グループ インコーポレイテッド 心病態を治療する方法
RU2019100033A (ru) * 2013-02-12 2019-02-12 Репликэл Лайф Сайенсиз Инк. Композиции и способы для лечения и восстановления сухожилий
WO2014128634A1 (en) 2013-02-20 2014-08-28 Pluristem Ltd. Gene and protein expression properties of adherent stromal cells cultured in 3d
WO2014141111A1 (en) 2013-03-14 2014-09-18 Pluristem Ltd. Methods for prevention and treatment of graft-versus-host disease
CN105246500A (zh) * 2013-04-05 2016-01-13 克劳迪娅·齐尔贝尔博格 基质金属蛋白酶及其用途
WO2015004609A2 (en) 2013-07-09 2015-01-15 Pluristem Ltd. Adherent cells from placenta and use thereof in treatment of injured tendons
CN105992816B (zh) 2013-11-16 2018-04-17 泰尔茂比司特公司 生物反应器中的细胞扩增
WO2015109329A1 (en) 2014-01-17 2015-07-23 Mimedx Group, Inc. Method for inducing angiogenesis
WO2015132729A1 (en) 2014-03-04 2015-09-11 Pluristem Ltd. Systems and methods for growing and harvesting cells
CN106232800B (zh) 2014-03-25 2020-07-03 泰尔茂比司特公司 介质的被动替代
WO2016049421A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled feed
US20180280447A1 (en) * 2014-10-29 2018-10-04 Sungkwang Medical Foundation Placenta-derived cells excreting c3 or c1r complement and composition containing same
US10364467B2 (en) 2015-01-13 2019-07-30 The Chinese University Of Hong Kong Using size and number aberrations in plasma DNA for detecting cancer
IL294058A (en) 2015-03-23 2022-08-01 Pluristem Ltd Use of adherent stromal cells for enhancing hematopoiesis in a subject in need thereof
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
WO2017039251A1 (ko) * 2015-08-28 2017-03-09 주식회사 차바이오텍 향상된 산후 부착형 세포 및 그의 용도
US20210205370A1 (en) * 2016-02-18 2021-07-08 Pluristem Ltd. Methods and compositions for treating cancers and neoplasms
GB201604304D0 (en) 2016-03-14 2016-04-27 Tigenix S A U Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease
CN109415696A (zh) 2016-05-25 2019-03-01 泰尔茂比司特公司 细胞扩增
US10851347B2 (en) 2016-06-06 2020-12-01 Pluristem Ltd. Altered adherent stromal cells and methods of producing and using same
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
CA3032160C (en) 2016-08-24 2024-05-28 Arthrex, Inc. Tissue hybrid for use in repairing, reconstructing or regenerating musculoskeletal degenerative processes or injuries
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
US12234441B2 (en) 2017-03-31 2025-02-25 Terumo Bct, Inc. Cell expansion
EP3656841A1 (en) 2017-03-31 2020-05-27 Terumo BCT, Inc. Cell expansion
CN106932571A (zh) * 2017-04-12 2017-07-07 广东国盛医学科技有限公司 基于rcn2标志物检测的心血管病检测方法及试剂盒
WO2018198012A1 (en) 2017-04-24 2018-11-01 Pluristem Ltd. Methods and compositions for treating neurological disorders
EP3615064A4 (en) * 2017-04-25 2021-02-24 Abraham J and Phyllis Katz Cord Blood Foundation ENRICHED CELL COMPOSITIONS AND THERAPEUTIC USES
US20200360444A1 (en) * 2017-12-28 2020-11-19 Kaneka Corporation Cell population including adhesive stem cells, production method therefor and pharmaceutical composition
CN109810992A (zh) * 2019-02-01 2019-05-28 天津师范大学 一种编码牙鲆胞外ATP水解酶CD39的cDNA全长序列及其应用
KR102143840B1 (ko) * 2019-02-22 2020-08-12 송미연 손상된 성상교세포 치료방법
US11511017B2 (en) 2019-03-12 2022-11-29 Arthrex, Inc. Ligament reconstruction
US20220160787A1 (en) * 2019-03-15 2022-05-26 Celularity Inc. Placenta derived adherent cells for improved xenoplantation
EP3883586A4 (en) * 2019-03-27 2022-09-07 Pluristem Ltd. Methods and compositions for aesthetic and cosmetic treatment and stimulating hair growth
US20200392448A1 (en) * 2019-06-14 2020-12-17 Ge Healthcare Uk Limited Monitoring of Cell Expansion
KR20200000415A (ko) * 2019-12-24 2020-01-02 (주)안트로젠 면역 질환 또는 염증성 질환의 예방 또는 치료용 중간엽줄기세포 배양액 및 이의 제조방법
EP4314244B1 (en) 2021-03-23 2025-07-23 Terumo BCT, Inc. Cell capture and expansion
US20240293471A1 (en) * 2021-09-09 2024-09-05 Pluri Biotech Ltd. Placental cell treatment for critical limb ischemia patient subpopulations
US12152699B2 (en) 2022-02-28 2024-11-26 Terumo Bct, Inc. Multiple-tube pinch valve assembly
USD1099116S1 (en) 2022-09-01 2025-10-21 Terumo Bct, Inc. Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device

Family Cites Families (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154600B (nl) 1971-02-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
NL154599B (nl) 1970-12-28 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking.
US3901654A (en) 1971-06-21 1975-08-26 Biological Developments Receptor assays of biologically active compounds employing biologically specific receptors
US3853987A (en) 1971-09-01 1974-12-10 W Dreyer Immunological reagent and radioimmuno assay
US3867517A (en) 1971-12-21 1975-02-18 Abbott Lab Direct radioimmunoassay for antigens and their antibodies
NL171930C (nl) 1972-05-11 1983-06-01 Akzo Nv Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen.
US3850578A (en) 1973-03-12 1974-11-26 H Mcconnell Process for assaying for biologically active molecules
US3935074A (en) 1973-12-17 1976-01-27 Syva Company Antibody steric hindrance immunoassay with two antibodies
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4034074A (en) 1974-09-19 1977-07-05 The Board Of Trustees Of Leland Stanford Junior University Universal reagent 2-site immunoradiometric assay using labelled anti (IgG)
US3984533A (en) 1975-11-13 1976-10-05 General Electric Company Electrophoretic method of detecting antigen-antibody reaction
US4098876A (en) 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
US4879219A (en) 1980-09-19 1989-11-07 General Hospital Corporation Immunoassay utilizing monoclonal high affinity IgM antibodies
US5011771A (en) 1984-04-12 1991-04-30 The General Hospital Corporation Multiepitopic immunometric assay
US4666828A (en) 1984-08-15 1987-05-19 The General Hospital Corporation Test for Huntington's disease
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4801531A (en) 1985-04-17 1989-01-31 Biotechnology Research Partners, Ltd. Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
US5902741A (en) 1986-04-18 1999-05-11 Advanced Tissue Sciences, Inc. Three-dimensional cartilage cultures
US4846835A (en) * 1987-06-15 1989-07-11 Grande Daniel A Technique for healing lesions in cartilage
US5272057A (en) 1988-10-14 1993-12-21 Georgetown University Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
US5192659A (en) 1989-08-25 1993-03-09 Genetype Ag Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
US5108989A (en) * 1990-04-04 1992-04-28 Genentech, Inc. Method of predisposing mammals to accelerated tissue repair
US5486359A (en) 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5281521A (en) 1992-07-20 1994-01-25 The Trustees Of The University Of Pennsylvania Modified avidin-biotin technique
US5877295A (en) * 1992-09-30 1999-03-02 The Center For Blood Research Antibodies which bind a subpopulation of Mac-1 (CD11b/CD18) molecules which mediate neutrophil adhesion to ICAM-1 and fibrinogen
US5629186A (en) 1994-04-28 1997-05-13 Lockheed Martin Corporation Porous matrix and method of its production
US5474687A (en) * 1994-08-31 1995-12-12 Activated Cell Therapy, Inc. Methods for enriching CD34+ human hematopoietic progenitor cells
US5736396A (en) 1995-01-24 1998-04-07 Case Western Reserve University Lineage-directed induction of human mesenchymal stem cell differentiation
US6132463A (en) 1995-05-19 2000-10-17 Etex Corporation Cell seeding of ceramic compositions
WO1997018299A1 (en) 1995-11-16 1997-05-22 Case Western Reserve University In vitro chondrogenic induction of human mesenchymal stem cells
DE69903800T2 (de) 1998-03-18 2003-10-02 Massachusetts Institute Of Technology, Cambridge Vaskularisierte perfundierte anordnungen für mikrogewebe und mikroorgane
FR2784284B1 (fr) * 1998-10-13 2000-12-15 Natural Implant Sa Procede de preparation d'un implant dentaire par immersion dans une culture de cellules mesenchymateuses, dispositif de culture de cellules pour la preparation dudit implant et implant obtenu
US6153432A (en) 1999-01-29 2000-11-28 Zen-Bio, Inc Methods for the differentiation of human preadipocytes into adipocytes
WO2000046349A1 (en) 1999-02-04 2000-08-10 Technion Research & Development Foundation Ltd. Method and apparatus for maintenance and expansion of hemopoietic stem cells and/or progenitor cells
IL145002A0 (en) * 1999-03-10 2002-06-30 Univ Pittsburgh Adipose-derived stem cells and lattices
WO2001062901A2 (en) 2000-02-26 2001-08-30 Artecel Sciences, Inc. Pleuripotent stem cells generated from adipose tissue-derived stromal cells and uses thereof
US7582292B2 (en) 2000-02-26 2009-09-01 Artecel, Inc. Adipose tissue derived stromal cells for the treatment of neurological disorders
AU7399201A (en) 2000-05-03 2001-11-12 Fidia Advanced Biopolymers Srl Biomaterials comprised of preadipocyte cells for soft tissue repair
KR100915483B1 (ko) * 2000-12-06 2009-09-03 로버트 제이 하리리 태반 줄기 세포의 회수 방법
US7311905B2 (en) * 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
ES2545899T3 (es) * 2001-02-14 2015-09-16 Anthrogenesis Corporation Placenta post-parto de mamíferos, su uso y células madre placentarias de la misma
JP2004528021A (ja) * 2001-02-14 2004-09-16 アンスロジェネシス コーポレーション 分娩後の哺乳動物の胎盤、その使用およびそれに由来する胎盤幹細胞
AU2002330077A1 (en) * 2001-09-21 2003-04-01 University Of Rochester Circadian control of stem/progenitor cell self-renewal and differentiation and of clock controlled gene expression
US9597395B2 (en) * 2001-12-07 2017-03-21 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
US7504099B2 (en) 2001-12-27 2009-03-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods of inducing or enhancing connective tissue repair
US7682803B2 (en) * 2005-10-13 2010-03-23 Anthrogenesis Corporation Immunomodulation using placental stem cells
MXPA04007732A (es) 2002-02-13 2004-10-15 Anthrogenesis Corp Celulas madre similares a las embrionarias, derivadas de la placenta de mamiferos despues del parto y usos y metodos de tratamiento usando dichas celulas.
JP2005517441A (ja) * 2002-02-19 2005-06-16 メディポスト・カンパニー・リミテッド 臍帯血由来の間葉幹細胞・前駆細胞の分離培養方法及び間葉組織への分化誘導方法
WO2003077865A2 (en) 2002-03-15 2003-09-25 Baxter International Inc. Methods and compositions for directing cells to target organs
WO2003082305A1 (en) * 2002-04-03 2003-10-09 Naohide Yamashita Drug containing human placenta-origin mesenchymal cells and process for producing vegf using the cells
US7498171B2 (en) * 2002-04-12 2009-03-03 Anthrogenesis Corporation Modulation of stem and progenitor cell differentiation, assays, and uses thereof
US20030235563A1 (en) * 2002-04-19 2003-12-25 Strom Stephen C. Placental derived stem cells and uses thereof
US20040161419A1 (en) 2002-04-19 2004-08-19 Strom Stephen C. Placental stem cells and uses thereof
CN1234429C (zh) * 2002-05-09 2006-01-04 中国人民解放军军事医学科学院野战输血研究所 一种人工皮肤及其制备方法与应用
JP2005528105A (ja) * 2002-05-30 2005-09-22 セルジーン・コーポレーション 細胞分化をモジュレートするため、並びに骨髄増殖性疾患及び骨髄異形成症候群を治療するためのjnk又はmkk阻害剤の使用方法
EP2110669B1 (en) * 2002-06-13 2011-08-03 Merck Patent GmbH Methods for the identification of allo-antigens and their use for cancer therapy and transplantation
US8455458B2 (en) * 2002-10-16 2013-06-04 Arthrodynamic Technologies, Animal Health Division, Inc. Composition and method for treating connective tissue damage
EA200500576A1 (ru) * 2002-11-01 2006-02-24 Бойз Таун Нэшнл Рисерч Хоспитал ИНДУЦИБЕЛЬНЫЙ ЛИГАНД ИНТЕГРИНА α1β1 И ПРИМЕНЕНИЯ
CN1901802B (zh) 2003-02-20 2010-12-29 马克罗珀尔生物外科公司 用脂肪组织来源的细胞治疗心血管疾病的方法
ATE524070T1 (de) * 2003-02-20 2011-09-15 Cytori Therapeutics Inc Verfahren zur verwendung von aus fettgewebe stammenden zellen bei der behandlung von herz- kreislauf-leiden
JP2004254674A (ja) * 2003-02-25 2004-09-16 Mutsumi Takagi 動物細胞の分化誘導培養方法
US20060172304A1 (en) 2003-02-27 2006-08-03 Elaine Fuchs Method for modulating epithelial stem cell lineage
CN1548529A (zh) * 2003-05-09 2004-11-24 中国人民解放军军事医学科学院基础医 一种人胎盘间充质干细胞的分离方法
EP1641915B1 (en) * 2003-06-27 2016-07-27 DePuy Synthes Products, Inc. Repair and regeneration of ocular tissue using postpartum-derived cells
WO2005007799A2 (en) * 2003-07-17 2005-01-27 Gamida-Cell Ltd. Methods for ex-vivo expanding stem/progenitor cells
JP4522994B2 (ja) 2003-08-01 2010-08-11 憲正 中村 スキャフォールドフリー自己組織性三次元人工組織(Scaffold−freeSelf−Organized3Dsynthetictissue)
FR2859381B1 (fr) 2003-09-05 2008-07-25 Centre Nat Rech Scient Utilisaton de cellules issues du tissu adipeux pour induire la formation d'un reseau vasculaire fonctionnel
DK2348103T3 (da) 2003-09-17 2019-09-30 Lorem Vascular Pte Ltd Fremgangsmåder til anvendelse af regenerative celler til behandling af perifer karsygdom og beslægtede sygdomme
TWI338714B (en) 2003-12-02 2011-03-11 Cathay General Hospital Method of isolation and enrichment of mesenchymal stem cells from amniotic fluid
US7534606B2 (en) 2004-01-12 2009-05-19 National Health Research Institutes Placental stem cell and methods thereof
BRPI0506839A (pt) * 2004-01-16 2007-06-12 Novartis Ag composições e métodos para induzir a cardiomiogênese
JP4445765B2 (ja) * 2004-02-05 2010-04-07 グンゼ株式会社 細胞培養装置
EP2824175B2 (en) 2004-03-22 2020-10-28 Mesoblast International Sàrl Mesenchymal stem cells and uses therefor
EP1756267A2 (en) * 2004-05-14 2007-02-28 Becton, Dickinson and Company Stem cell populations and methods of use
CN1746296A (zh) * 2004-09-09 2006-03-15 中国人民解放军军事医学科学院基础医学研究所 一种基于胎盘来源间充质干细胞的组织工程化骨及其制造方法
CN1746295A (zh) * 2004-09-09 2006-03-15 中国人民解放军军事医学科学院基础医学研究所 一种基于胎盘来源间充质干细胞的组织工程化软骨及其制造方法
CN100336567C (zh) * 2004-10-19 2007-09-12 北京科宇联合干细胞生物技术有限公司 医用角膜贴片
EP1833496B1 (en) 2004-12-23 2013-07-31 Ethicon, Incorporated Treatment of stroke and other acute neural degenerative disorders using postpartum derived cells
EP1830862B1 (en) 2004-12-30 2012-12-19 PrimeGen Biotech LLC Adipose-derived stem cells for tissue regeneration and wound healing
CN103361301A (zh) 2005-03-31 2013-10-23 斯丹姆涅恩有限公司 高度纯化来自羊膜的细胞群
US20070059288A1 (en) * 2005-03-31 2007-03-15 Dinsmore Jonathan H Treatment for heart disease
US20080317720A1 (en) 2005-04-14 2008-12-25 Noritoshi Nagaya Fat-Derived Progenitor Cell and Use Thereof
WO2006138552A2 (en) * 2005-06-15 2006-12-28 Government Of The Usa, As Represented By The Secretary, Dept. Of Health & Human Services Tissue engineered cartilage, method of making same, therapeutic and cosmetic surgical applications using same
WO2007047465A1 (en) 2005-10-13 2007-04-26 Anthrogenesis Corporation Production of oligodendrocytes from placenta-derived stem cells
EP1937326B1 (en) 2005-10-21 2018-09-12 CellResearch Corporation Pte Ltd Isolation and cultivation of stem/progenitor cells from the amniotic membrane of umbilical cord and uses of cells differentiated therefrom
EP1979050B1 (en) * 2005-12-28 2017-04-19 DePuy Synthes Products, Inc. Treatment of peripheral vascular disease using postpartum-derived cells
PT2471905T (pt) 2005-12-29 2019-01-11 Celularity Inc Populações de células estaminais placentárias
GB0600972D0 (en) 2006-01-18 2006-03-01 Univ Leeds Enrichment of cells
US20100233130A1 (en) * 2006-02-06 2010-09-16 Pluristem Ltd. Method and Apparatus for Maintenance and Expansion of Hematopoietic Stem Cells From Mononuclear Cells
CA2646384C (en) 2006-03-23 2020-03-24 Pluristem Ltd. Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy
WO2011132087A1 (en) 2010-04-23 2011-10-27 Pluristem Ltd. Adherent stromal cells derived from plancentas of multiple donors and uses thereof
US20110293583A1 (en) 2006-03-23 2011-12-01 Pluristem Ltd. Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy
US20110171182A1 (en) 2006-03-23 2011-07-14 Pluristem Ltd. Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy
EP1845154A1 (en) 2006-04-12 2007-10-17 RNL Bio Co., Ltd. Multipotent stem cells derived from placenta tissue and cellular therapeutic agents comprising the same
DE102006043625B4 (de) * 2006-09-12 2012-02-23 Eberhard-Karls-Universität Tübingen Universitätsklinikum Verfahren zur Isolierung und/oder Identifizierung von mesenchymalen Stammzellen (MSC)
US20080138415A1 (en) * 2006-09-26 2008-06-12 Mehboob Hussain Composition and method for producing composition for constructing tissue, and tissue construct
CN101631852A (zh) * 2006-10-23 2010-01-20 人类起源公司 用胎盘细胞群治疗骨缺损的方法和组合物
RS52921B (sr) 2007-02-12 2014-02-28 Anthrogenesis Corporation Lečenje inflamatornih bolesti upotrebom placentnih matičnih ćelija
CA2697265A1 (en) * 2007-08-09 2009-02-19 Genzyme Corporation Method of treating autoimmune disease with mesenchymal stem cells
RU2010109698A (ru) 2007-09-19 2011-09-27 Плуристем Лтд. (Il) Адгезивные клетки жировой ткани или плаценты и их использование в лечебных целях
CA2725637A1 (en) 2008-05-27 2009-12-03 Pluristem Ltd. Methods of treating inflammatory colon diseases
US20110256108A1 (en) 2008-09-02 2011-10-20 Moran Meiron Methods of selection of cells for transplantation
US9096827B2 (en) 2008-09-02 2015-08-04 Pluristem Ltd. Adherent cells from placenta tissue and use thereof in therapy
EP2334783B1 (en) 2008-09-02 2016-06-22 Pluristem Ltd. Adherent cells from placenta tissue and use thereof in therapy
EP2806023B1 (en) 2009-11-30 2015-09-23 Pluristem Ltd. Adherent cells from placenta and use of same in disease treatment
US9757419B2 (en) 2010-05-27 2017-09-12 Pluristem Ltd. Skeletal muscle regeneration using mesenchymal system cells
US20140017209A1 (en) 2011-03-22 2014-01-16 Pluristem Ltd. Methods for treating radiation or chemical injury
WO2012140519A2 (en) 2011-04-15 2012-10-18 Pluristem Ltd. Methods and systems for harvesting cells
AU2013311289B2 (en) 2012-09-04 2017-11-16 Pluristem Ltd. Methods for prevention and treatment of preeclampsia
CA2882108C (en) 2012-09-06 2016-01-05 Pluristem Ltd. Three dimensional devices for supporting monolayer cell growth and methods of culturing cells therewith
HK1209972A1 (en) 2012-10-31 2016-04-15 普拉里斯坦有限公司 Method and device for thawing biological material

Also Published As

Publication number Publication date
IL248955B (en) 2020-03-31
JP2010539228A (ja) 2010-12-16
EP3103463A1 (en) 2016-12-14
EP2591789B1 (en) 2016-06-22
IL272587A (en) 2020-03-31
JP6294517B2 (ja) 2018-03-14
IL248956B (en) 2019-07-31
AU2008300185B2 (en) 2013-09-05
CN107050057A (zh) 2017-08-18
HRP20120887T1 (en) 2012-12-31
JP2017095516A (ja) 2017-06-01
PT2200622E (pt) 2012-11-06
IL204566A (en) 2016-11-30
WO2009037690A1 (en) 2009-03-26
EP2591789A3 (en) 2014-01-01
US20140242039A1 (en) 2014-08-28
IL272587B2 (en) 2023-02-01
HK1180241A1 (en) 2013-10-18
EP3103463B1 (en) 2020-01-01
HK1145800A1 (en) 2011-05-06
EP2200622B2 (en) 2015-07-29
JP5931132B2 (ja) 2016-06-08
EP2200622A1 (en) 2010-06-30
JP2014208682A (ja) 2014-11-06
KR20140107677A (ko) 2014-09-04
PL2200622T5 (pl) 2016-08-31
CN107028981B (zh) 2021-04-20
CA2699664A1 (en) 2009-03-26
US20100209403A1 (en) 2010-08-19
BRPI0815946B8 (pt) 2021-05-25
CN107028981A (zh) 2017-08-11
KR20150100959A (ko) 2015-09-02
AU2008300185A1 (en) 2009-03-26
ZA201001929B (en) 2011-02-23
US9517248B2 (en) 2016-12-13
SI2200622T1 (sl) 2013-01-31
ES2392729T3 (es) 2012-12-13
HRP20120887T4 (hr) 2015-12-04
US8529888B2 (en) 2013-09-10
BRPI0815946B1 (pt) 2020-12-01
KR101738285B1 (ko) 2017-05-29
EP2200622B1 (en) 2012-08-08
ES2392729T5 (es) 2015-08-28
KR20100075924A (ko) 2010-07-05
RU2010109698A (ru) 2011-09-27
SI2200622T2 (sl) 2015-09-30
US20180256648A9 (en) 2018-09-13
EP2591789A2 (en) 2013-05-15
CA2699664C (en) 2016-10-18
RU2015141314A (ru) 2018-12-26
IL248956A0 (en) 2017-01-31
CN107050057B (zh) 2021-04-20
KR101738323B1 (ko) 2017-05-19
JP2016094464A (ja) 2016-05-26
RU2709780C2 (ru) 2019-12-20
US20220378847A1 (en) 2022-12-01
IL204566A0 (en) 2010-11-30
BRPI0815946A2 (pt) 2018-06-26
IL272587B (en) 2022-10-01
EP2591789B2 (en) 2022-07-20
KR20160081994A (ko) 2016-07-08
MX2010003019A (es) 2010-04-30
JP6560381B2 (ja) 2019-08-14
US20130323213A1 (en) 2013-12-05
CN101861156A (zh) 2010-10-13
IL248955A0 (en) 2017-01-31
PL2200622T3 (pl) 2013-01-31
JP2018109031A (ja) 2018-07-12

Similar Documents

Publication Publication Date Title
CN300882121S (zh) 布(5236)
CN300862142S (zh) 插片(29)
CN300858924S (zh) 罐贴
CN300817174S (zh) 布(1)
CN300812707S (zh) 控制器
CN300805770S (zh) 床头(815)
CN300793995S (zh) 面料(忘不了品牌视觉元素17)
CN300782530S (zh) 瓷砖(cp0741-17)
CN300761448S (zh) 铅笔包装袋(284)
CN300752836S (zh) 鼠标(jy-37)
CN300750984S (zh) 标识(062851)
CN300745626S (zh) 无框阳台用型材(ⅱ)
CN300744295S (zh) 钟面(807)
CN300741483S (zh) 新定时器秤
CN300730239S (zh) 订书机(v1)
CN300730205S (zh) 挤压式注浆机配料箱液压全自动搅拌装置
CN300730141S (zh) 电路板(热电阻输入端子板)
CN300729976S (zh) 石英开关(单屏)
CN300729959S (zh) 用于安装束线的固定器
CN300729873S (zh) 金属轮毂(365)
CN300729780S (zh) 客车(6129hgn)
CN300729731S (zh) 工艺品(背水姑娘)
CN300729609S (zh) 包装袋
CN300729588S (zh) 瓶(沐浴总管)
CN300729480S (zh) 包装盒