RU2015139557A - Уменьшение риска развития аутоимунного заболевания - Google Patents

Уменьшение риска развития аутоимунного заболевания Download PDF

Info

Publication number
RU2015139557A
RU2015139557A RU2015139557A RU2015139557A RU2015139557A RU 2015139557 A RU2015139557 A RU 2015139557A RU 2015139557 A RU2015139557 A RU 2015139557A RU 2015139557 A RU2015139557 A RU 2015139557A RU 2015139557 A RU2015139557 A RU 2015139557A
Authority
RU
Russia
Prior art keywords
hydrolyzate
autoimmune disease
seq
group
nutritional composition
Prior art date
Application number
RU2015139557A
Other languages
English (en)
Inventor
Дёрк ХОНДМАНН
ТОЛЬ Эрик А.Ф. ВАН
Габриэле ГРОСС
Марьеке Х. ШОЭМАКЕР
Теартсе Тим ЛАМБЕРС
Original Assignee
ЭмДжейЭн Ю.Эс. Холдингс ЛЛК
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ЭмДжейЭн Ю.Эс. Холдингс ЛЛК filed Critical ЭмДжейЭн Ю.Эс. Холдингс ЛЛК
Publication of RU2015139557A publication Critical patent/RU2015139557A/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/01Hydrolysed proteins; Derivatives thereof
    • A61K38/012Hydrolysed proteins; Derivatives thereof from animals
    • A61K38/018Hydrolysed proteins; Derivatives thereof from animals from milk
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Obesity (AREA)
  • Transplantation (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Claims (13)

1. Способ уменьшения риска развития аутоиммунного заболевания, лечения аутоиммунного заболевания и/или уменьшения симптомов аутоиммунного заболевания у субъекта путем введения субъекту композиции, содержащей гидролизат казеина, причем гидролизат состоит из пептидов с молекулярной массой более 500 Да.
2. Способ по п. 1, причем аутоиммунное заболевание выбрано из группы, состоящей из сахарного диабета 1-го типа, болезни Крона, язвенного колита, метаболического синдрома, заболеваний, связанных с HLA-DQ8, заболеваний, связанных с HLA-DQ2, и целиакии.
3. Способ по п. 2, причем аутоиммунное заболевание представляет собой сахарный диабет 1-го типа.
4. Способ по п. 1, причем гидролизат содержит по меньшей мере три пептида, выбранных из группы, состоящей из SEQ ID NO: 1-68.
5. Способ по п. 4, причем гидролизат содержит по меньшей мере три пептида, выбранных из группы, состоящей из SEQ ID NO: 1-24.
6. Способ по п. 5, причем гидролизат содержит по меньшей мере три пептида, выбранных из группы, состоящей из SEQ ID NO: 1-15.
7. Способ по п. 4, причем гидролизат содержит пептид с SEQ ID NO: 1 и по меньшей мере три пептида, выбранных из группы, состоящей из SEQ ID NO: 2-68.
8. Способ по п. 1, причем гидролизат вводят в питательную композицию, содержащую липидную или жировую фазу и источник белков.
9. Способ по п. 8, причем питательная композиция содержит от приблизительно 0,1 до приблизительно 1 г/100 ккал пребиотической композиции, причем пребиотическая композиция содержит по меньшей мере 20% олигосахарида.
10. Способ по п. 8, причем питательная композиция дополнительно содержит от приблизительно 5 до приблизительно 100 мг/100 ккал источника длинноцепочечных полиненасыщенных жирных кислот, который содержит докозагексаеновую кислоту.
11. Способ по п. 10, причем питательная композиция дополнительно содержит арахидоновую кислоту.
12. Способ по п. 1, причем субъект представляет собой ребенка или подростка.
13. Способ по п. 1, причем питательный состав дополнительно содержит один или несколько углеводов, нуклеиновых кислот, липидов, минералов, анаболических питательных веществ, витаминов, антиоксидантов, пробиотических бактериальных штаммов и липотропных веществ.
RU2015139557A 2013-03-15 2014-03-11 Уменьшение риска развития аутоимунного заболевания RU2015139557A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/839,212 US9289461B2 (en) 2013-03-15 2013-03-15 Reducing the risk of autoimmune disease
US13/839,212 2013-03-15
PCT/US2014/023630 WO2014150566A1 (en) 2013-03-15 2014-03-11 Reducing the risk of autoimmune disease

Publications (1)

Publication Number Publication Date
RU2015139557A true RU2015139557A (ru) 2017-05-02

Family

ID=50483516

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2015139557A RU2015139557A (ru) 2013-03-15 2014-03-11 Уменьшение риска развития аутоимунного заболевания

Country Status (15)

Country Link
US (1) US9289461B2 (ru)
EP (1) EP2968438A1 (ru)
CN (1) CN105073126A (ru)
AR (1) AR095335A1 (ru)
AU (1) AU2014237022A1 (ru)
BR (1) BR112015017909A2 (ru)
CA (1) CA2905817A1 (ru)
HK (1) HK1216994A1 (ru)
MX (1) MX2015011927A (ru)
PE (1) PE20152003A1 (ru)
PH (1) PH12015502100B1 (ru)
RU (1) RU2015139557A (ru)
SG (1) SG11201505692QA (ru)
TW (1) TW201521756A (ru)
WO (1) WO2014150566A1 (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10251928B2 (en) 2014-11-06 2019-04-09 Mead Johnson Nutrition Company Nutritional supplements containing a peptide component and uses thereof
US20170020950A1 (en) * 2015-07-23 2017-01-26 Mead Johnson Nutrition Company Methods for modulating kinases
AU2017261723B2 (en) 2016-05-11 2023-02-09 University Of Southern California Fasting mimicking diet (FMD) as an immunoregulatory treatment for gastrointestinal autoimmune/inflammatory diseases.
AU2017394032B8 (en) 2017-01-21 2020-10-22 Guangzhou Hanfang Pharmaceutical Co., Ltd. Use of paeoniflorin-6'-o-benzenesulfonate in treatment of sjögren's syndrome
CN117384270B (zh) * 2023-10-13 2024-07-16 华南理工大学 一种酪蛋白源dpp-iv抑制六肽及其制备方法与应用

Family Cites Families (106)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2064092C2 (de) 1970-12-28 1983-06-01 Bayer Ag, 5090 Leverkusen Inhibitoren für Glykosidhydrolasen aus Actinomyceten
US3937817A (en) 1973-02-28 1976-02-10 Bayer Aktiengesellschaft Pharmaceutical compositions containing a saccharase inhibitor
US4016260A (en) 1974-07-22 1977-04-05 Toyama Chemical Co., Ltd. Novel polypeptide produced by pseudomonas
FR2474828B1 (fr) 1980-02-01 1983-09-09 Agronomique Inst Nat Rech Procede de traitement d'une matiere premiere a base de caseine, contenant des phosphocaseinates de cations bivalents, produits obtenus et application
FR2474829B1 (fr) 1980-02-01 1983-09-09 Agronomique Inst Nat Rech Procede de traitement d'une matiere a base de caseine contenant des phosphocaseinates de cations monovalents ou leurs derives, produits obtenus et applications
US4491589A (en) 1982-05-17 1985-01-01 The Trustees Of Columbia University In The City Of New York Amino acid solutions for parenteral nutrition and methods of formulation and use
DK589785A (da) 1985-12-18 1987-06-19 Samuelsson Ernst Gunnar Peptidpraeparat, fremgangsmaade til fremstilling deraf samt anvendelse af peptidpraeparatet
IT1190349B (it) 1986-06-16 1988-02-16 Prodotti Formenti Srl Composizioni farmaceutiche ad attivita' sequestrante degli acidi biliari contenenti colestiramina quale principio attivo,e procedimento per prepararle
FR2608050B1 (fr) 1986-12-15 1990-04-13 Bellon Labor Sa Roger Procede de preparation d'un melange peptidique riche en di- et tri-peptides, utilisable notamment en nutrition artificielle et en dietetique, melange ainsi obtenu, et utilisation de ce melange en nutrition artificielle et en dietetique
US5230902A (en) 1988-04-29 1993-07-27 Immunotec Research Corporation Undenatured whey protein concentrate to improve active systemic humoral immune response
US5102871A (en) 1989-04-24 1992-04-07 Kyowa Hakko Kogyo Co., Ltd. Nutrient composition
FI904074A0 (fi) 1989-08-28 1990-08-17 Milupa Ag Protein-, peptid- och aminosyrablandningar med optimerad aminosyrasammansaettning samt deras anvaendning foer framstaellning av naering foer prematur- och dibarn samt av tillsatser till modersmjoelk.
US5407957A (en) 1990-02-13 1995-04-18 Martek Corporation Production of docosahexaenoic acid by dinoflagellates
PH30997A (en) 1990-03-12 1997-12-23 Ciba Geigy Antipathologenically effective compositions comprising lytic peptides and hydrolytic enzymes.
ZA92452B (en) 1991-01-24 1992-10-28 Martek Corp Microbial oil mixtures and uses thereof
US5308832A (en) 1992-07-27 1994-05-03 Abbott Laboratories Nutritional product for persons having a neurological injury
GB9310472D0 (en) 1993-05-20 1993-07-07 Univ Warwick Phenylalanine-free protein and dna coding thereof
GB9312369D0 (en) 1993-06-16 1993-07-28 Sandoz Nutrition Ltd Organic compounds
US5405637A (en) * 1993-06-30 1995-04-11 Bristol-Myers Squibb Company Milk protein partial hydrolysate and infant formula containing same
US5714472A (en) 1993-12-23 1998-02-03 Nestec Ltd. Enternal formulation designed for optimized nutrient absorption and wound healing
US5723446A (en) 1993-12-23 1998-03-03 Nestec Ltd. Enteral formulation designed for optimized nutrient absorption and wound healing
US5605893A (en) 1994-03-15 1997-02-25 Children's Hospital Of Los Angeles Method of using a therapeutic food composition to diminish blood sugar fluctuations in diabetic patients
US5643880A (en) 1994-05-26 1997-07-01 Abbott Laboratories Product for inhibition of attachment of H. influenzae to human cells
DE69536000D1 (de) 1994-11-04 2009-10-22 A2 Corp Ltd Selektionsverfahren für nicht-diabetogene milch oder milchprodukte sowie hierdurch erfasste milch oder milchprodukte
US5821217A (en) 1995-10-27 1998-10-13 Beth Israel Deaconess Medical Center, Inc. Enteral formulation: low in fat and containing protein hydrolysates
IT1277964B1 (it) 1995-12-27 1997-11-12 Biosistema Di Pier Luigi Spara Prodotto derivato da latte, sostanzialmente esente da betacaseina di mammifero non umano e relativo uso
KR100194074B1 (ko) 1996-02-21 1999-06-15 박종헌 글루텐 펩타이드를 유효성분으로 포함하는 미네랄 흡수 촉진제
CA2260892A1 (en) 1996-07-17 1998-01-22 Nicada, Inc. Appetite suppression
KR100221124B1 (ko) 1996-09-23 1999-10-01 한상기 신규한 카제인 및 그 제조방법
NL1005037C2 (nl) 1997-01-17 1998-07-20 Nl Zuivelonderzoek Inst Werkwijze voor het selectief afbreken van melkeiwit, in het bijzonder voor het selectief hydrolyseren van caseïne/caseïnaat in aanwezigheid van andere melkeiwitten, in het bijzonder wei-eiwitten.
CA2340223A1 (en) 1998-08-12 2000-02-24 Morinaga Milk Industry Co., Ltd. Nutritional compositions for preventing or treating hyperlipoproteinemia
JP2000063284A (ja) * 1998-08-21 2000-02-29 Terumo Corp 炎症性腸疾患再燃防止剤
US6077558A (en) 1998-12-23 2000-06-20 Bristol-Myers Squibb Company Elemental nutritional products
US6905702B1 (en) 1999-11-08 2005-06-14 Children's Hospital Los Angeles Methods for regulating blood glucose and appetite suppression in type 2 diabetics
GB9927603D0 (en) 1999-11-22 2000-01-19 Nestle Sa Use of a milk protein hydrolysate in the treatment of diabetes
EP1112693B1 (en) 1999-12-30 2006-03-22 Kerry Group Services Ltd Composition comprising carbohydrate and peptide material and its use as an energy supplement after or during physical exercise or as a metabolic nutrient for oral consumption
NL1014380C2 (nl) 2000-02-14 2001-08-15 Friesland Brands Bv Darmwandversterkend voedingsmiddel.
US6207638B1 (en) 2000-02-23 2001-03-27 Pacifichealth Laboratories, Inc. Nutritional intervention composition for enhancing and extending satiety
US7666996B2 (en) 2000-03-01 2010-02-23 Peptera Pharmaceuticals Ltd Casein derived peptides and uses thereof
IL134830A0 (en) 2000-03-01 2001-05-20 Chay 13 Medical Res Group N V Peptides and immunostimulatory and anti-bacterial pharmaceutical compositions containing them
TWI268138B (en) 2000-05-11 2006-12-11 Kanebo Seiyaku Ltd Composition containing peptide and electrolyte excretion enhancing substance, and food containing the same
WO2002000865A1 (fr) 2000-06-28 2002-01-03 Fuji Nihon Seito Corporation Nouvelle synthase d'inuline et procede de production d'insuline par cette derniere
GB0016189D0 (en) 2000-06-30 2000-08-23 Pepsyn Ltd Cosmetic composition
WO2002019832A1 (en) 2000-09-08 2002-03-14 New Zealand Dairy Board MILK CONTAINING β-CASEIN WITH PROLINE AT POSITION 67 DOES NOT AGGRAVATE NEUROLOGICAL DISORDERS
WO2002032231A1 (en) 2000-10-19 2002-04-25 Edens, Luppo Protein hydrolysates
WO2003005836A2 (en) 2001-07-10 2003-01-23 Trustees Of Boston University Modified-fat nutritional products useful for preventing or treating obesity
WO2003007730A1 (en) 2001-07-18 2003-01-30 Dsm Ip Assets B.V. Process for the hydrolysis of milk proteins
DE10149668A1 (de) 2001-10-09 2003-04-10 Numico Res B V Insulinmimetische Aminosäuresequenzen
JP2003137804A (ja) 2001-10-31 2003-05-14 Morinaga Milk Ind Co Ltd インターロイキン−18誘導剤
DE60218064T2 (de) 2001-11-21 2007-11-15 Morinaga Milk Industry Co. Ltd. Neues peptid mit angiotensinkonvertase hemmender wirkung
EP1359157A1 (en) 2002-04-29 2003-11-05 Société des Produits Nestlé S.A. Metallo-proteinase inhibitory agent
US7460960B2 (en) 2002-05-10 2008-12-02 Epitome Biosystems, Inc. Proteome epitope tags and methods of use thereof in protein modification analysis
US20050256057A1 (en) 2002-06-04 2005-11-17 Luppo Edens Protein hydrolysate rich in tripeptides
FR2841473B1 (fr) 2002-06-27 2004-09-17 Ingredia Utilisation d'au moins un peptide de la caseine s2 a activite inhbitrice de l'enzyme de conversion de l'engiotensine i pour la preparation de medicaments, d'aliments et de complements alimentaires
EP1534314B1 (en) 2002-09-04 2014-10-22 DSM IP Assets B.V. A nutritional and therapeutic composition of an insulin sensitizer and a peptide fraction
TWI317636B (en) 2002-11-22 2009-12-01 Meiji Dairies Corp Nutritional compositions for liver disease patients or for patients underhigh levels of invasive stress
EP1568377A1 (en) 2002-11-29 2005-08-31 Morinaga Milk Industry Co., Ltd. Cysteine protease inhibitor
EP1589106B1 (en) 2002-12-29 2010-12-01 Toudai Tlo, Ltd. Adiponectin receptor and gene coding for the same
CA2523410A1 (en) 2003-05-05 2004-11-18 Unilever Plc Hydrolysed casein product comprising tripeptides ipp and/or vpp
WO2005027953A2 (en) 2003-09-23 2005-03-31 Dsm Ip Assets B.V. Use of proline specific endoproteases to hydrolyse peptides and proteins
PT1721612E (pt) 2003-10-24 2009-09-02 Nutricia Nv Oligossacarídeos imunomoduladores
BE1015863A6 (nl) 2004-01-19 2005-10-04 Huybrechts Lucas Anticariogene proteinen & peptiden & sacchariden.
EP1718158B1 (en) 2004-01-28 2014-07-02 Andromeda Bio Tech Ltd. Hsp therapy in conjunction with a low antigenicity diet
EP1568707A1 (en) 2004-02-26 2005-08-31 Puleva Biotech, S.A. Antihypertensive peptides from casein hydrolysates
MXPA06010014A (es) 2004-03-01 2007-03-07 Peptera Pharmaceuticals Ltd Peptidos derivados de la caseina y usos terapeuticos de los mismos.
KR20070034528A (ko) 2004-05-27 2007-03-28 캄피나 네덜란드 홀딩 베.붸. Dpp-iv 매개 질병의 예방 및/또는 치료용 의약품제조를 위한 단백질 가수분해물의 용도
DE102004040452A1 (de) 2004-08-20 2006-02-23 N.V. Nutricia Peptidgemisch
KR100560127B1 (ko) 2004-09-04 2006-03-13 한국기초과학지원연구원 인산화 단백질 분석용 겔-내 표지화 및 겔-내 단리 방법및 이를 이용한 단백질의 인산화 위치 동정 방법
EP1811867A2 (en) 2004-11-12 2007-08-01 N.V. Nutricia Food composition comprising a protein- and a lipid fraction for rapidly attenuating inflammatory responses
ES2381118T3 (es) 2004-12-23 2012-05-23 Campina Nederland Holding B.V. Hidrolizado de proteínas enriquecido en péptidos de inhibición de DPP-IV y su uso
CN101106914B (zh) 2005-01-18 2012-12-26 帝斯曼知识产权资产管理有限公司 营养药物性组合物
EP1843778B1 (en) 2005-02-03 2009-12-23 DSM IP Assets B.V. Compositions comprising epigallocatechin gallate and protein hydrolysate
ATE425671T1 (de) 2005-02-09 2009-04-15 Unilever Nv Lebensmittelprodukte mit hydrolysierten milchfeststoffen mit verbessertem geschmack
JP2008539203A (ja) 2005-04-28 2008-11-13 ディーエスエム アイピー アセッツ ビー.ブイ. 新規栄養補助組成物
EP1874140B1 (en) 2005-04-28 2011-02-09 Unilever N.V. Peptides having a health benefit and compositions comprising them
WO2006118459A1 (en) 2005-04-29 2006-11-09 Campina Nederland Holding B.V. Antiviral peptides
ES2319475B1 (es) 2005-06-08 2010-02-16 Consejo Superior Investig. Cientificas Peptidos bioactivos identificados en hidrolizados enzimaticos de caseinas lacteas y procedimiento de obtencion.
CN101212911B (zh) 2005-07-01 2012-12-05 努特里希亚公司 含水解的蛋白质的婴儿营养品
GB0523806D0 (en) 2005-11-23 2006-01-04 Micromass Ltd Mass spectrometer
EP1954299B1 (en) 2005-11-30 2016-01-13 Campina Nederland Holding B.V. Use of a protein hydrolysate for enhancing activity of glucagon-like peptide-1
WO2008054192A1 (en) 2006-11-02 2008-05-08 N.V. Nutricia Use of nutritional compositions for preventing disorders
ATE509624T1 (de) 2005-12-23 2011-06-15 Nutricia Nv Zusammensetzung enthaltend mehrfach ungesättigte fettsäuren, proteine, mangan und/oder molybden und nukleotide/nukleoside, zur behandlung von demenz
US20100167979A1 (en) 2006-02-09 2010-07-01 Calpis Co. Ltd Rheumatoid arthritis-preventive agent for oral intake
WO2007107587A2 (en) 2006-03-22 2007-09-27 Dsm Ip Assets B.V. Cholesterol lowering protein hydrolysates
EP2003991A1 (en) 2006-04-12 2008-12-24 DSM IP Assets B.V. Novel nutraceutical compositions
EP2039366A4 (en) 2006-04-21 2010-01-06 Meiji Seika Kaisha COMPOSITION CONTAINING PEPTIDE AS ACTIVE INGREDIENT
WO2007125946A1 (ja) 2006-04-28 2007-11-08 Snow Brand Milk Products Co., Ltd. ペプチド
KR20080003637A (ko) 2006-07-03 2008-01-08 한상기 다이어트효과가 우수한 기능성 유산균발효조성물
US8691213B2 (en) 2006-08-04 2014-04-08 SHS International Protein free formula
ES2358367T3 (es) 2006-08-09 2011-05-10 Dsm Ip Assets B.V. Complejos de caseína.
NL1032840C2 (nl) 2006-11-09 2008-05-13 Friesland Brands Bv Probiotische hydrolysaatvoeding voor kinderen.
NL1033521C2 (nl) 2007-03-08 2008-09-09 Friesland Brands Bv Kindervoedingen met geoptimaliseerde aminozuursamenstelling.
US20090252729A1 (en) 2007-05-14 2009-10-08 Farrington Graham K Single-chain Fc (scFc) regions, binding polypeptides comprising same, and methods related thereto
WO2008147562A2 (en) 2007-05-25 2008-12-04 Childrens's Medical Center Corporation Dietary formulations and methods for treatment of inflammation and other disorders
WO2008153429A2 (en) 2007-06-11 2008-12-18 Uniwersytet Jagiellonski A protease from staphylococcus aureus, particularly spia or spib, peptides it recognises and their use
CA2699006A1 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
EP2230300A4 (en) 2007-10-24 2012-08-08 Otsuka Chemical Holdings Co Ltd POLYPEPTIDE WITH IMPROVED EFFECTOR FUNCTION
WO2009138762A2 (en) * 2008-05-15 2009-11-19 Regen Therapeutics Plc Therapeutic use of peptides
US8859210B2 (en) 2008-10-17 2014-10-14 Mead Johnson Nutrition Company Method for identifying allergenic proteins and peptides
JP5735734B2 (ja) 2009-04-16 2015-06-17 雪印メグミルク株式会社 脂質代謝改善剤
EP2253324A1 (en) 2009-04-30 2010-11-24 Consejo Superior De Investigaciones Cientificas Use of a casein-derived peptide and compositions thereof as antihypertensive
EP2295535A1 (en) 2009-09-11 2011-03-16 Mead Johnson Nutrition Company Probiotic material
ES2524067T3 (es) 2009-12-04 2014-12-03 Mjn U.S. Holdings Llc Formulación nutricional que comprende un hidrolizado que contiene péptidos de leche de vaca y/o péptidos derivados del mismo para la inducción de tolerancia
BR112012017978A2 (pt) 2010-01-19 2016-05-03 Abbott Lab fórmulas nutricionais contendo simbióticos
CA2790996A1 (en) 2010-02-24 2011-09-01 Morinaga Milk Industry Co. Ltd. Therapeutic agent for eating disorders
EP2514435A1 (en) 2011-04-19 2012-10-24 Nestec S.A. Infant formula for use in the prevention of cardiovascular diseases

Also Published As

Publication number Publication date
EP2968438A1 (en) 2016-01-20
CN105073126A (zh) 2015-11-18
US20140274892A1 (en) 2014-09-18
PH12015502100A1 (en) 2016-01-18
BR112015017909A2 (pt) 2017-11-21
US9289461B2 (en) 2016-03-22
PE20152003A1 (es) 2016-01-29
HK1216994A1 (zh) 2016-12-16
AR095335A1 (es) 2015-10-07
WO2014150566A1 (en) 2014-09-25
TW201521756A (zh) 2015-06-16
MX2015011927A (es) 2015-12-01
CA2905817A1 (en) 2014-09-25
AU2014237022A1 (en) 2015-08-13
SG11201505692QA (en) 2015-08-28
PH12015502100B1 (en) 2016-01-18

Similar Documents

Publication Publication Date Title
Donati Zeppa et al. Mutual interactions among exercise, sport supplements and microbiota
Li et al. Health benefits of docosahexaenoic acid and its bioavailability: A review
Diez-Gutiérrez et al. Gamma-aminobutyric acid and probiotics: Multiple health benefits and their future in the global functional food and nutraceuticals market
RU2015139359A (ru) Способ ослабления провоспалительной реакции
Marion-Letellier et al. IBD: in food we trust
Stadelmann et al. Arginine consumption by the intestinal parasite Giardia intestinalis reduces proliferation of intestinal epithelial cells
JP6852980B2 (ja) 低カロリー高タンパク質の栄養組成物及び該栄養組成物を用いる方法
RU2015139557A (ru) Уменьшение риска развития аутоимунного заболевания
Liu et al. Health benefits, food applications, and sustainability of microalgae-derived N-3 PUFA
Foolchand et al. Malnutrition and dietary habits alter the immune system which may consequently influence SARS-CoV-2 virulence: a review
Alcock et al. Fatty acids from diet and microbiota regulate energy metabolism
JP2016516419A (ja) 同時トレーニングに続いて筋タンパク質合成を高めるための方法
RU2013146517A (ru) Композиции и способы, пригодные для облегчения возрастных заболеваний
RU2014150662A (ru) Диетотерапия целиакии и пищевой аллергии
RU2012139658A (ru) Композиции и способы для доставки питательных веществ
RU2016140158A (ru) Лечение аутоиммунной реакции и рассеянного склероза
BR112015032572A2 (pt) composições e métodos para melhorar o desempenho durante exercícios
Qi et al. Beta-hydroxybutyrate: a dual function molecular and immunological barrier function regulator
Vilahur et al. Lactobacillus plantarum CECT 7315/7316 intake modulates the acute and chronic innate inflammatory response
Castro-López et al. Key stress response mechanisms of probiotics during their journey through the digestive system: a review
Kaur et al. Weight Loss Associated with High Protein Diet Intake in Obesity: Interactions of Gut Microbiota in Protein Sources Influencing this Positive Effect
RU2013128920A (ru) Способ ингибирования патогенов с использованием питательной композиции
RU2015133023A (ru) Активация адипонектина с использованием гидролизата казеина
Ma et al. Effects of in ovo feeding and dietary addition oils on growth performance and immune function of broiler chickens
Garibotto et al. How to overcome anabolic resistance in dialysis-treated patients?