RU2014143531A3 - - Google Patents
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- RU2014143531A3 RU2014143531A3 RU2014143531A RU2014143531A RU2014143531A3 RU 2014143531 A3 RU2014143531 A3 RU 2014143531A3 RU 2014143531 A RU2014143531 A RU 2014143531A RU 2014143531 A RU2014143531 A RU 2014143531A RU 2014143531 A3 RU2014143531 A3 RU 2014143531A3
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- RU
- Russia
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
- A61K39/005—Trypanosoma antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21061—Kexin (3.4.21.61), i.e. proprotein convertase subtilisin/kexin type 9
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Mycology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Tropical Medicine & Parasitology (AREA)
- Urology & Nephrology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23954109P | 2009-09-03 | 2009-09-03 | |
US61/239,541 | 2009-09-03 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2012107657/10A Division RU2538162C2 (ru) | 2009-09-03 | 2010-08-23 | Вакцина против pcsk9 |
Publications (2)
Publication Number | Publication Date |
---|---|
RU2014143531A RU2014143531A (ru) | 2016-05-20 |
RU2014143531A3 true RU2014143531A3 (ru) | 2018-06-22 |
Family
ID=43413463
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2012107657/10A RU2538162C2 (ru) | 2009-09-03 | 2010-08-23 | Вакцина против pcsk9 |
RU2014143531A RU2014143531A (ru) | 2009-09-03 | 2014-10-29 | Вакцина против PCSK9 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2012107657/10A RU2538162C2 (ru) | 2009-09-03 | 2010-08-23 | Вакцина против pcsk9 |
Country Status (30)
Country | Link |
---|---|
US (4) | US8889144B2 (ru) |
EP (3) | EP2473605B1 (ru) |
JP (5) | JP2013503623A (ru) |
KR (3) | KR101512053B1 (ru) |
CN (3) | CN104548089B (ru) |
AR (2) | AR078247A1 (ru) |
AU (1) | AU2010290931B2 (ru) |
BR (1) | BR112012004807A2 (ru) |
CA (2) | CA2846746A1 (ru) |
CO (1) | CO6501190A2 (ru) |
DK (1) | DK2473605T3 (ru) |
ES (1) | ES2670576T3 (ru) |
HK (3) | HK1174056A1 (ru) |
HU (1) | HUE037416T2 (ru) |
IL (2) | IL218229A (ru) |
MX (1) | MX2012002639A (ru) |
MY (1) | MY163512A (ru) |
NO (1) | NO2473605T3 (ru) |
NZ (3) | NZ599059A (ru) |
PE (3) | PE20161560A1 (ru) |
PH (2) | PH12016500004A1 (ru) |
PL (1) | PL2473605T3 (ru) |
PT (1) | PT2473605T (ru) |
RU (2) | RU2538162C2 (ru) |
SA (3) | SA110310687B1 (ru) |
SG (3) | SG10201401516XA (ru) |
SI (1) | SI2473605T1 (ru) |
TR (1) | TR201808222T4 (ru) |
TW (1) | TWI400085B (ru) |
WO (1) | WO2011027257A2 (ru) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101721904B1 (ko) | 2008-08-29 | 2017-04-11 | 오럴 헬스 오스트레일리아 피티와이 엘티디 | P.진지발리스 감염의 예방, 치료 및 진단 |
MY160201A (en) | 2008-12-09 | 2017-02-28 | Coley Pharm Group Inc | Immunostimulatory oligonucleotides |
US8552165B2 (en) * | 2008-12-09 | 2013-10-08 | Heather Davis | Immunostimulatory oligonucleotides |
GB201005005D0 (en) * | 2010-03-25 | 2010-05-12 | Angeletti P Ist Richerche Bio | New vaccine |
WO2012131504A1 (en) * | 2011-03-02 | 2012-10-04 | Pfizer Inc. | Pcsk9 vaccine |
EP2532359A1 (en) | 2011-06-10 | 2012-12-12 | Affiris AG | CETP fragments |
PL2570135T3 (pl) | 2011-09-13 | 2016-07-29 | Affiris Ag | Szczepionka PCSK9 |
US9255154B2 (en) | 2012-05-08 | 2016-02-09 | Alderbio Holdings, Llc | Anti-PCSK9 antibodies and use thereof |
EP2703483A1 (en) | 2012-08-29 | 2014-03-05 | Affiris AG | PCSK9 peptide vaccine |
KR20150072444A (ko) * | 2012-10-17 | 2015-06-29 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 하나 이상의 스트렙토코커스 뉴모니애 캡슐 사카라이드 컨쥬게이트 및 해모필루스 인플루엔자로부터의 단백질 E 및/또는 PilA를 포함하는 단백질 성분을 포함하는 면역원성 조성물 |
US10058630B2 (en) * | 2012-10-22 | 2018-08-28 | Concievalve, Llc | Methods for inhibiting stenosis, obstruction, or calcification of a stented heart valve or bioprosthesis |
US10117923B2 (en) | 2012-11-07 | 2018-11-06 | Vacplanta Limited | Production of an immunogen using a plant virus |
US20150274784A1 (en) * | 2012-11-07 | 2015-10-01 | Vacplanta Limted | Production of an Immunogen Using a Plant Virus |
TWI641382B (zh) * | 2013-01-31 | 2018-11-21 | 韓美藥品股份有限公司 | 於包含因子vii之組成物中使病毒失活之方法 |
CN104043120B (zh) | 2013-03-13 | 2017-05-31 | 南京赛威信生物医药有限公司 | 乙型肝炎疫苗 |
WO2015123291A1 (en) | 2014-02-11 | 2015-08-20 | The Usa, As Represented By The Secretary, Dept. Of Health And Human Services | Pcsk9 vaccine and methods of using the same |
CN106459209B (zh) * | 2014-02-28 | 2019-10-11 | 阿费里斯股份公司 | Pcsk9疫苗 |
CN104558199B (zh) * | 2014-09-05 | 2018-07-06 | 成都康弘生物科技有限公司 | 一种治疗高胆固醇血症的融合蛋白制备及其用途 |
JP6975132B2 (ja) * | 2015-07-20 | 2021-12-01 | ゾエティス・サービシーズ・エルエルシー | リポソームアジュバント組成物 |
MX2018004802A (es) | 2015-10-19 | 2018-09-06 | Cadila Healthcare Ltd | Nuevo adyuvante y composición de vacuna que contiene el mismo. |
KR20180079406A (ko) * | 2015-11-03 | 2018-07-10 | 아피리스 아게 | 인간 환자에서 자가-항원에 대한 예방접종을 위한 방법 |
WO2017164409A1 (ja) * | 2016-03-25 | 2017-09-28 | 国立大学法人大阪大学 | 疾患の要因となる生体内タンパク質を標的とするコンジュゲートワクチン |
KR102449308B1 (ko) * | 2016-06-24 | 2022-10-04 | 에프. 호프만-라 로슈 아게 | 심혈관 질환의 치료를 위한 조성물 및 방법 |
CN106822881A (zh) * | 2016-12-09 | 2017-06-13 | 四川大学 | 一种针对pcsk9的抗高血脂蛋白疫苗 |
CA3058567A1 (en) | 2017-04-13 | 2018-10-18 | Cadila Healthcare Limited | Novel peptide based pcsk9 vaccine |
CN107488215A (zh) * | 2017-07-19 | 2017-12-19 | 邱志华 | 人前蛋白转化酶枯草溶菌素9免疫原性肽段及其载体疫苗 |
MX2022000094A (es) * | 2019-07-04 | 2022-04-27 | Cadila Healthcare Ltd | Vacuna a base de angptl3 para el tratamiento de enfermedad hepática. |
BR112022014845A2 (pt) * | 2020-01-28 | 2022-12-13 | United Biomedical Inc | Imunógenos peptídicos de alvejamento de pcsk9 e formulações do mesmo para prevenção e tratamento de distúrbios mediados por pcsk9 |
IL296071A (en) | 2020-03-01 | 2022-11-01 | Valneva Austria Gmbh | Sars-cov-2 virus vaccine with adjuvant cytidine-phosphoguanosine |
WO2022147373A1 (en) * | 2020-12-31 | 2022-07-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Antibody-guided pcsk9-mimicking immunogens lacking 9-residue sequence overlap with human proteins |
WO2023161526A1 (en) | 2022-02-28 | 2023-08-31 | Tridem Bioscience Gmbh & Co Kg | A CONJUGATE CONSISTING OF OR COMPRISING AT LEAST A ß-GLUCAN OR A MANNAN |
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