RU2014134845A - Терапевтическое средство против диабета - Google Patents
Терапевтическое средство против диабета Download PDFInfo
- Publication number
- RU2014134845A RU2014134845A RU2014134845A RU2014134845A RU2014134845A RU 2014134845 A RU2014134845 A RU 2014134845A RU 2014134845 A RU2014134845 A RU 2014134845A RU 2014134845 A RU2014134845 A RU 2014134845A RU 2014134845 A RU2014134845 A RU 2014134845A
- Authority
- RU
- Russia
- Prior art keywords
- therapeutic
- group
- impaired glucose
- prophylactic agent
- glucose metabolism
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title claims abstract 17
- 206010012601 diabetes mellitus Diseases 0.000 title claims abstract 6
- 230000000069 prophylactic effect Effects 0.000 claims abstract 16
- 239000003795 chemical substances by application Substances 0.000 claims abstract 13
- 201000010099 disease Diseases 0.000 claims abstract 10
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract 10
- 230000004153 glucose metabolism Effects 0.000 claims abstract 10
- 230000001771 impaired effect Effects 0.000 claims abstract 10
- WYKHSBAVLOPISI-UHFFFAOYSA-N 2-phenyl-1,3-thiazole Chemical class C1=CSC(C=2C=CC=CC=2)=N1 WYKHSBAVLOPISI-UHFFFAOYSA-N 0.000 claims abstract 4
- 150000003839 salts Chemical class 0.000 claims abstract 4
- 208000001072 type 2 diabetes mellitus Diseases 0.000 claims abstract 3
- 125000004195 4-methylpiperazin-1-yl group Chemical group [H]C([H])([H])N1C([H])([H])C([H])([H])N(*)C([H])([H])C1([H])[H] 0.000 claims abstract 2
- 208000002705 Glucose Intolerance Diseases 0.000 claims abstract 2
- 206010022489 Insulin Resistance Diseases 0.000 claims abstract 2
- 239000004480 active ingredient Substances 0.000 claims abstract 2
- 125000003545 alkoxy group Chemical group 0.000 claims abstract 2
- 239000003472 antidiabetic agent Substances 0.000 claims abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims abstract 2
- 229940125904 compound 1 Drugs 0.000 claims abstract 2
- 125000004093 cyano group Chemical group *C#N 0.000 claims abstract 2
- BQSJTQLCZDPROO-UHFFFAOYSA-N febuxostat Chemical compound C1=C(C#N)C(OCC(C)C)=CC=C1C1=NC(C)=C(C(O)=O)S1 BQSJTQLCZDPROO-UHFFFAOYSA-N 0.000 claims abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims abstract 2
- 229940126904 hypoglycaemic agent Drugs 0.000 claims abstract 2
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 claims abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims abstract 2
- 125000000587 piperidin-1-yl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 claims abstract 2
- 201000009104 prediabetes syndrome Diseases 0.000 claims abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 1
- 125000006828 (C2-C7) alkoxycarbonyl group Chemical group 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012015351 | 2012-01-27 | ||
| JP2012-015351 | 2012-01-27 | ||
| PCT/JP2013/051627 WO2013111870A1 (ja) | 2012-01-27 | 2013-01-25 | 糖尿病の治療薬 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2014134845A true RU2014134845A (ru) | 2016-03-20 |
Family
ID=48873581
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2014134845A RU2014134845A (ru) | 2012-01-27 | 2013-01-25 | Терапевтическое средство против диабета |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20150005506A1 (enExample) |
| EP (1) | EP2808018B1 (enExample) |
| JP (1) | JP5924699B2 (enExample) |
| KR (1) | KR20140134266A (enExample) |
| CN (1) | CN104066430A (enExample) |
| AR (1) | AR089812A1 (enExample) |
| AU (1) | AU2013212865A1 (enExample) |
| BR (1) | BR112014017902A2 (enExample) |
| CA (1) | CA2862602A1 (enExample) |
| HK (1) | HK1201209A1 (enExample) |
| IN (1) | IN2014DN05972A (enExample) |
| MX (1) | MX2014008484A (enExample) |
| RU (1) | RU2014134845A (enExample) |
| TW (1) | TW201334779A (enExample) |
| WO (1) | WO2013111870A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104628671B (zh) * | 2015-02-10 | 2016-04-13 | 佛山市赛维斯医药科技有限公司 | 含苯基脒结构的硝基苯噻唑羧酸酰胺类化合物及用途 |
| CN104610190B (zh) * | 2015-02-10 | 2016-08-17 | 佛山市赛维斯医药科技有限公司 | 一类含环丙基脒结构的卤代苯基噻唑羧酸酰胺类化合物及用途 |
| CN104610188B (zh) * | 2015-02-10 | 2016-07-27 | 佛山市赛维斯医药科技有限公司 | 含苯基脒结构的腈基苯噻唑羧酸酰胺类化合物、其制备及用途 |
| CN104628672A (zh) * | 2015-02-10 | 2015-05-20 | 佛山市赛维斯医药科技有限公司 | 一类含苯基脒结构的烷氧苯基噻唑羧酸酰胺类化合物及用途 |
| CN104628673A (zh) * | 2015-02-10 | 2015-05-20 | 佛山市赛维斯医药科技有限公司 | 一类含叔丁基脒结构的腈基苯噻唑羧酸酰胺类化合物及用途 |
| KR102473677B1 (ko) * | 2015-08-17 | 2022-12-02 | 삼성디스플레이 주식회사 | 액정 표시 장치 |
| JP6732004B2 (ja) | 2016-02-19 | 2020-07-29 | 国立大学法人鳥取大学 | 認知症治療薬または予防薬 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2073981C (en) * | 1990-11-30 | 2002-01-08 | Shiro Kondo | 2-arylthiazole derivatives and pharmaceutical composition thereof |
| HUP9902721A2 (hu) * | 1997-11-25 | 1999-12-28 | The Procter & Gamble Co. | Tömény textillágyító készítmény és ehhez alkalmazható magas telítetlenségű textillágyító vegyület |
| US20050074442A1 (en) * | 2002-03-13 | 2005-04-07 | Natarajan Ranganathan | Compositions and methods for augmenting kidney function |
| WO2007018687A1 (en) * | 2005-07-21 | 2007-02-15 | University Of Florida Research Foundation, Inc. | Compositions and methods for treatment and prevention of hyperuricemia related health consequences |
| US8557831B2 (en) * | 2004-07-21 | 2013-10-15 | University Of Florida Research Foundation, Inc. | Compositions and methods for treatment and prevention of insulin resistance |
| WO2007019153A2 (en) | 2005-08-03 | 2007-02-15 | Tap Pharmaceutical Products, Inc. | Methods for treating hypertension |
| CA2630639A1 (en) * | 2005-11-21 | 2007-05-31 | Tap Pharmaceutical Products, Inc. | Treatment of qt interval prolongation and diseases associated therewith |
| JP2007210978A (ja) * | 2006-02-13 | 2007-08-23 | Hiroshima Univ | 耐糖能障害、ｉｉ型糖尿病、高脂血症、メタボリックシンドローム、内臓脂肪型肥満、脂肪肝または非アルコール性脂肪性肝炎の予防・治療剤 |
| CA2669935A1 (en) | 2006-11-13 | 2008-05-29 | Takeda Pharmaceuticals North America, Inc. | Methods for preserving renal function using xanthine oxidoreductase inhibitors |
| BRPI0819847B1 (pt) * | 2007-11-27 | 2022-01-11 | Ardea Biosciences, Inc | Compostos e composições |
| PT2266989E (pt) * | 2008-03-31 | 2015-11-23 | C&C Res Lab | Derivados heterocíclicos |
| MX2010011603A (es) * | 2008-04-30 | 2011-01-25 | Wellstat Therapeutics Corp | Compuestos de tetrazol para reducir el acido urico. |
| EP2291189B1 (en) * | 2008-05-22 | 2014-10-01 | AstraZeneca AB | Method for treating hyperuricemia employing an sglt2 inhibitor and composition containing same |
| WO2010045636A1 (en) * | 2008-10-19 | 2010-04-22 | Johnson Richard J | Therapeutic compositions and methods for treating chronic kidney disease associated with a metabolic imbalance |
| WO2011022757A1 (en) * | 2009-08-24 | 2011-03-03 | Queensland University Of Technology | Purine-targeted diagnosis and therapy of wounds |
| EP2582812B1 (en) * | 2010-06-16 | 2018-01-24 | Takeda Pharmaceuticals U.S.A., Inc. | Novel modified release dosage forms of xanthine oxidoreductase inhibitor or xanthine oxidase inhibitors |
| AR082022A1 (es) * | 2010-06-25 | 2012-11-07 | Teijin Pharma Ltd | Agente terapeutico de liberacion sostenida para la hipertension y la disfuncion renal |
-
2013
- 2013-01-25 WO PCT/JP2013/051627 patent/WO2013111870A1/ja not_active Ceased
- 2013-01-25 US US14/372,961 patent/US20150005506A1/en not_active Abandoned
- 2013-01-25 JP JP2013555326A patent/JP5924699B2/ja not_active Expired - Fee Related
- 2013-01-25 CA CA2862602A patent/CA2862602A1/en not_active Abandoned
- 2013-01-25 IN IN5972DEN2014 patent/IN2014DN05972A/en unknown
- 2013-01-25 BR BR112014017902A patent/BR112014017902A2/pt not_active IP Right Cessation
- 2013-01-25 KR KR1020147020342A patent/KR20140134266A/ko not_active Withdrawn
- 2013-01-25 CN CN201380006730.6A patent/CN104066430A/zh active Pending
- 2013-01-25 HK HK15101890.2A patent/HK1201209A1/xx unknown
- 2013-01-25 EP EP13740913.2A patent/EP2808018B1/en not_active Not-in-force
- 2013-01-25 AU AU2013212865A patent/AU2013212865A1/en not_active Abandoned
- 2013-01-25 TW TW102102886A patent/TW201334779A/zh unknown
- 2013-01-25 MX MX2014008484A patent/MX2014008484A/es unknown
- 2013-01-25 RU RU2014134845A patent/RU2014134845A/ru not_active Application Discontinuation
- 2013-01-25 AR ARP130100233A patent/AR089812A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IN2014DN05972A (enExample) | 2015-06-26 |
| EP2808018A4 (en) | 2015-07-15 |
| EP2808018B1 (en) | 2018-03-14 |
| US20150005506A1 (en) | 2015-01-01 |
| AU2013212865A1 (en) | 2014-08-14 |
| HK1201209A1 (en) | 2015-08-28 |
| WO2013111870A1 (ja) | 2013-08-01 |
| CN104066430A (zh) | 2014-09-24 |
| JP5924699B2 (ja) | 2016-05-25 |
| JPWO2013111870A1 (ja) | 2015-05-11 |
| EP2808018A1 (en) | 2014-12-03 |
| TW201334779A (zh) | 2013-09-01 |
| CA2862602A1 (en) | 2013-08-01 |
| MX2014008484A (es) | 2014-10-14 |
| BR112014017902A2 (pt) | 2017-08-22 |
| KR20140134266A (ko) | 2014-11-21 |
| AR089812A1 (es) | 2014-09-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20160830 |