RU2014114015A - Способы лечения воспалительных расстройств с использованием антител против m-csf - Google Patents

Способы лечения воспалительных расстройств с использованием антител против m-csf Download PDF

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Publication number
RU2014114015A
RU2014114015A RU2014114015/10A RU2014114015A RU2014114015A RU 2014114015 A RU2014114015 A RU 2014114015A RU 2014114015/10 A RU2014114015/10 A RU 2014114015/10A RU 2014114015 A RU2014114015 A RU 2014114015A RU 2014114015 A RU2014114015 A RU 2014114015A
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Russia
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ser
amino acid
acid sequence
antibody
seq
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RU2014114015/10A
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English (en)
Russian (ru)
Inventor
Мартин ХЕДЖЕН
Дебора Энн ЯНГ
Хит М. ГУЭЙ
Кириаки ДУНУССИ-ДЖОАННОПОУЛОС
Судхакар СРИДХАРАН
Аннетт ДАИХЛ
Гэйл КОМЕР
Марго Мэри О'ТУЛ
Джин Элизабет БИБ
Роберт ФОДЖЕЛ
Марек ХОНЧАРЕНКО
Дэвид БИДЛЕР
Падмалата Сункара РЕДДИ
ШАК Давид Йоганнес ФОН
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Пфайзер Инк.
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Publication of RU2014114015A publication Critical patent/RU2014114015A/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/243—Colony Stimulating Factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
RU2014114015/10A 2011-11-08 2012-11-02 Способы лечения воспалительных расстройств с использованием антител против m-csf RU2014114015A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161557175P 2011-11-08 2011-11-08
US61/557,175 2011-11-08
PCT/IB2012/056125 WO2013068902A1 (fr) 2011-11-08 2012-11-02 Procédés de traitement de troubles inflammatoires utilisant des anticorps anti-m-csf

Publications (1)

Publication Number Publication Date
RU2014114015A true RU2014114015A (ru) 2015-12-20

Family

ID=47216377

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2014114015/10A RU2014114015A (ru) 2011-11-08 2012-11-02 Способы лечения воспалительных расстройств с использованием антител против m-csf

Country Status (14)

Country Link
US (1) US20140286959A1 (fr)
EP (1) EP2776467A1 (fr)
JP (1) JP2013100281A (fr)
KR (1) KR20140076602A (fr)
CN (1) CN104271599A (fr)
AU (1) AU2012335247A1 (fr)
BR (1) BR112014011115A2 (fr)
CA (1) CA2856149A1 (fr)
HK (1) HK1205522A1 (fr)
IL (1) IL232190A0 (fr)
IN (1) IN2014CN04183A (fr)
MX (1) MX2014005570A (fr)
RU (1) RU2014114015A (fr)
WO (1) WO2013068902A1 (fr)

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SG11201507871XA (en) * 2013-04-12 2015-10-29 Morphosys Ag Antibodies targeting m-csf
WO2015160786A1 (fr) * 2014-04-14 2015-10-22 Brigham And Women's Hospital, Inc. Procédé de diagnostic, de pronostic et de traitement de la néphrite lupique
CN105985435B (zh) * 2015-01-30 2019-10-15 嘉和生物药业有限公司 全人源her2抗体的突变抗体及其编码基因和应用
MX2018010948A (es) 2016-03-11 2019-06-20 Scholar Rock Inc INMUNOGLOBULINAS DE ENLACE A TGFß1 Y USOS DE LAS MISMAS.
SG10201606949QA (en) 2016-08-19 2018-03-28 Singapore Health Serv Pte Ltd Immunosuppressive composition for use in treating immunological disorders
WO2018129329A1 (fr) * 2017-01-06 2018-07-12 Scholar Rock, Inc. INHIBITEURS SPÉCIFIQUES D'UNE ISOFORME, PERMISSIFS AU CONTEXTE DE TGFβ1 ET LEUR UTILISATION
WO2018183366A1 (fr) 2017-03-28 2018-10-04 Syndax Pharmaceuticals, Inc. Polythérapies d'anticorps csf-1r ou csf-1 et thérapie reposant sur des lymphocytes t
WO2018213665A1 (fr) 2017-05-19 2018-11-22 Syndax Pharmaceuticals, Inc. Polythérapies

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Also Published As

Publication number Publication date
HK1205522A1 (en) 2015-12-18
IL232190A0 (en) 2014-06-30
MX2014005570A (es) 2014-05-30
AU2012335247A1 (en) 2014-05-29
CA2856149A1 (fr) 2013-05-16
WO2013068902A1 (fr) 2013-05-16
EP2776467A1 (fr) 2014-09-17
US20140286959A1 (en) 2014-09-25
JP2013100281A (ja) 2013-05-23
KR20140076602A (ko) 2014-06-20
IN2014CN04183A (fr) 2015-07-17
CN104271599A (zh) 2015-01-07
BR112014011115A2 (pt) 2017-06-13

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