RU2013141413A - Производные изоксазолина для борьбы с беспозвоночными паразитами - Google Patents
Производные изоксазолина для борьбы с беспозвоночными паразитами Download PDFInfo
- Publication number
- RU2013141413A RU2013141413A RU2013141413/04A RU2013141413A RU2013141413A RU 2013141413 A RU2013141413 A RU 2013141413A RU 2013141413/04 A RU2013141413/04 A RU 2013141413/04A RU 2013141413 A RU2013141413 A RU 2013141413A RU 2013141413 A RU2013141413 A RU 2013141413A
- Authority
- RU
- Russia
- Prior art keywords
- alkyl
- mono
- halogen
- cyano
- alkoxy
- Prior art date
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- 244000045947 parasite Species 0.000 title claims abstract 8
- -1 hydroxy- Chemical class 0.000 claims abstract 26
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract 25
- 229910052736 halogen Inorganic materials 0.000 claims abstract 24
- 150000002367 halogens Chemical class 0.000 claims abstract 22
- 125000004093 cyano group Chemical group *C#N 0.000 claims abstract 15
- 150000001875 compounds Chemical class 0.000 claims abstract 12
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims abstract 9
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims abstract 8
- 125000005420 sulfonamido group Chemical group S(=O)(=O)(N*)* 0.000 claims abstract 8
- 125000004076 pyridyl group Chemical group 0.000 claims abstract 6
- 125000000714 pyrimidinyl group Chemical group 0.000 claims abstract 5
- 125000005843 halogen group Chemical group 0.000 claims abstract 3
- 239000000203 mixture Substances 0.000 claims abstract 3
- XFXPMWWXUTWYJX-UHFFFAOYSA-N Cyanide Chemical compound N#[C-] XFXPMWWXUTWYJX-UHFFFAOYSA-N 0.000 claims abstract 2
- 150000001204 N-oxides Chemical class 0.000 claims abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims abstract 2
- 150000003839 salts Chemical class 0.000 claims abstract 2
- 125000000217 alkyl group Chemical group 0.000 claims 13
- 125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 claims 9
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 claims 9
- 125000004738 (C1-C6) alkyl sulfinyl group Chemical group 0.000 claims 8
- 125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 claims 8
- 125000006700 (C1-C6) alkylthio group Chemical group 0.000 claims 8
- 125000004737 (C1-C6) haloalkoxy group Chemical group 0.000 claims 8
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 claims 7
- 229910052799 carbon Inorganic materials 0.000 claims 7
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 7
- 229910052739 hydrogen Inorganic materials 0.000 claims 7
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 6
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 claims 6
- 229910052760 oxygen Inorganic materials 0.000 claims 5
- 229910052717 sulfur Inorganic materials 0.000 claims 5
- 125000006771 (C1-C6) haloalkylthio group Chemical group 0.000 claims 4
- XTFIVUDBNACUBN-UHFFFAOYSA-N 1,3,5-trinitro-1,3,5-triazinane Chemical compound [O-][N+](=O)N1CN([N+]([O-])=O)CN([N+]([O-])=O)C1 XTFIVUDBNACUBN-UHFFFAOYSA-N 0.000 claims 4
- 241001465754 Metazoa Species 0.000 claims 4
- 125000003545 alkoxy group Chemical group 0.000 claims 4
- 125000005119 alkyl cycloalkyl group Chemical group 0.000 claims 4
- 125000004306 triazinyl group Chemical group 0.000 claims 4
- 125000006650 (C2-C4) alkynyl group Chemical group 0.000 claims 3
- 125000003342 alkenyl group Chemical group 0.000 claims 3
- 125000000304 alkynyl group Chemical group 0.000 claims 3
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 claims 3
- 125000001188 haloalkyl group Chemical group 0.000 claims 3
- 125000000335 thiazolyl group Chemical group 0.000 claims 3
- 125000004767 (C1-C4) haloalkoxy group Chemical group 0.000 claims 2
- 125000004749 (C1-C6) haloalkylsulfinyl group Chemical group 0.000 claims 2
- 125000004741 (C1-C6) haloalkylsulfonyl group Chemical group 0.000 claims 2
- 125000006656 (C2-C4) alkenyl group Chemical group 0.000 claims 2
- 125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 claims 2
- 125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 claims 2
- 125000001963 4 membered heterocyclic group Chemical group 0.000 claims 2
- 125000000339 4-pyridyl group Chemical group N1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 claims 2
- 125000002373 5 membered heterocyclic group Chemical group 0.000 claims 2
- 125000004070 6 membered heterocyclic group Chemical group 0.000 claims 2
- 125000004453 alkoxycarbonyl group Chemical group 0.000 claims 2
- 125000004414 alkyl thio group Chemical group 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- 125000004438 haloalkoxy group Chemical group 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 125000004527 pyrimidin-4-yl group Chemical group N1=CN=C(C=C1)* 0.000 claims 2
- 125000004528 pyrimidin-5-yl group Chemical group N1=CN=CC(=C1)* 0.000 claims 2
- 125000004916 (C1-C6) alkylcarbonyl group Chemical group 0.000 claims 1
- 125000006645 (C3-C4) cycloalkyl group Chemical group 0.000 claims 1
- 125000001462 1-pyrrolyl group Chemical group [*]N1C([H])=C([H])C([H])=C1[H] 0.000 claims 1
- 125000000389 2-pyrrolyl group Chemical group [H]N1C([*])=C([H])C([H])=C1[H] 0.000 claims 1
- 125000001397 3-pyrrolyl group Chemical group [H]N1C([H])=C([*])C([H])=C1[H] 0.000 claims 1
- KDDQRKBRJSGMQE-UHFFFAOYSA-N 4-thiazolyl Chemical compound [C]1=CSC=N1 KDDQRKBRJSGMQE-UHFFFAOYSA-N 0.000 claims 1
- CWDWFSXUQODZGW-UHFFFAOYSA-N 5-thiazolyl Chemical group [C]1=CN=CS1 CWDWFSXUQODZGW-UHFFFAOYSA-N 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 claims 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims 1
- 239000002270 dispersing agent Substances 0.000 claims 1
- 125000002541 furyl group Chemical group 0.000 claims 1
- 125000005842 heteroatom Chemical group 0.000 claims 1
- 125000002883 imidazolyl group Chemical group 0.000 claims 1
- 125000001786 isothiazolyl group Chemical group 0.000 claims 1
- 125000000842 isoxazolyl group Chemical group 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 1
- 125000001715 oxadiazolyl group Chemical group 0.000 claims 1
- 125000002971 oxazolyl group Chemical group 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 125000003373 pyrazinyl group Chemical group 0.000 claims 1
- 125000003226 pyrazolyl group Chemical group 0.000 claims 1
- 125000002098 pyridazinyl group Chemical group 0.000 claims 1
- 125000000168 pyrrolyl group Chemical group 0.000 claims 1
- SNOOUWRIMMFWNE-UHFFFAOYSA-M sodium;6-[(3,4,5-trimethoxybenzoyl)amino]hexanoate Chemical compound [Na+].COC1=CC(C(=O)NCCCCCC([O-])=O)=CC(OC)=C1OC SNOOUWRIMMFWNE-UHFFFAOYSA-M 0.000 claims 1
- 125000003718 tetrahydrofuranyl group Chemical group 0.000 claims 1
- 125000001113 thiadiazolyl group Chemical group 0.000 claims 1
- 125000001544 thienyl group Chemical group 0.000 claims 1
- 125000002053 thietanyl group Chemical group 0.000 claims 1
- 125000001425 triazolyl group Chemical group 0.000 claims 1
- JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical compound O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/84—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms six-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,4
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/24—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing the groups, or; Thio analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Pest Control & Pesticides (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Agronomy & Crop Science (AREA)
- Veterinary Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH2472011 | 2011-02-10 | ||
| CH00247/2011 | 2011-02-10 | ||
| PCT/EP2012/052241 WO2012107533A1 (en) | 2011-02-10 | 2012-02-09 | Isoxazoline derivatives for controlling invertebrate pests |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2013141413A true RU2013141413A (ru) | 2015-03-20 |
Family
ID=45607737
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2013141413/04A RU2013141413A (ru) | 2011-02-10 | 2012-02-09 | Производные изоксазолина для борьбы с беспозвоночными паразитами |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20130324538A1 (enExample) |
| EP (1) | EP2673273A1 (enExample) |
| JP (1) | JP2014505089A (enExample) |
| CN (1) | CN103347880B (enExample) |
| AR (1) | AR085354A1 (enExample) |
| AU (1) | AU2012215440B2 (enExample) |
| BR (1) | BR112013020520A2 (enExample) |
| CA (1) | CA2826067A1 (enExample) |
| CL (1) | CL2013002296A1 (enExample) |
| CO (1) | CO6731114A2 (enExample) |
| MX (1) | MX2013009211A (enExample) |
| RU (1) | RU2013141413A (enExample) |
| TW (1) | TWI511966B (enExample) |
| WO (1) | WO2012107533A1 (enExample) |
| ZA (1) | ZA201305226B (enExample) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UY33403A (es) * | 2010-06-17 | 2011-12-30 | Novartis Ag | Compuestos orgánicos con novedosas isoxazolinas, sus n-óxidos, s-óxidos y sales |
| AR086113A1 (es) | 2011-04-30 | 2013-11-20 | Abbott Lab | Isoxazolinas como agentes terapeuticos |
| WO2012155352A1 (en) * | 2011-05-19 | 2012-11-22 | Eli Lilly And Company | Dihydroisoxazole compounds, parasiticidal uses and formulations thereof |
| RU2763496C2 (ru) | 2012-02-06 | 2021-12-29 | БЁРИНГЕР ИНГЕЛЬХАЙМ ЭНИМАЛ ХЕЛТ ЮЭсЭй ИНК. | Паразитицидные пероральные ветеринарные композиции, включающие системно действующие активные агенты, способы и применение этих композиций и способов |
| JO3626B1 (ar) | 2012-02-23 | 2020-08-27 | Merial Inc | تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها |
| PT2953942T (pt) | 2013-02-06 | 2018-01-17 | Bayer Cropscience Ag | Derivados de pirazol substituídos com halogéneo como agentes pesticidas |
| WO2014206909A1 (en) | 2013-06-24 | 2014-12-31 | Basf Se | Thiophene- or furan-substituted isothiazoline compounds as pesticides |
| AU2014342241B2 (en) | 2013-11-01 | 2017-09-14 | Boehringer Ingelheim Animal Health USA Inc. | Antiparasitic and pesticidal isoxazoline compounds |
| HUE055444T2 (hu) * | 2013-12-20 | 2021-11-29 | Intervet Int Bv | Izoxazolinszármazákok felhasználása baromfiak arthropodafertõzéseinek kezelésére vagy megelõzésére |
| ES2971061T3 (es) | 2013-12-20 | 2024-06-03 | Intervet Int Bv | Composiciones de isoxazolina y uso de las mismas en la prevención o el tratamiento de infestaciones parasitarias en animales |
| BR112016017527B1 (pt) | 2014-01-03 | 2021-01-05 | Bayer Animal Health Gmbh | compostos, usos de compostos, composições farmacêuticas, processo para produzir composições e método não terapêutico para controlar pragas |
| CN106455560B (zh) | 2014-04-17 | 2020-12-22 | 勃林格殷格翰动物保健美国公司 | 用于保护动物免受寄生物的丙二腈化合物的用途 |
| TW201607938A (zh) | 2014-07-15 | 2016-03-01 | 拜耳作物科學股份有限公司 | 作為殺蟲劑之新穎芳基三唑基吡啶類 |
| US20170232024A1 (en) | 2014-08-04 | 2017-08-17 | Jerry Tan Eye Surgery Pte Ltd | Pharmaceutical compositions for demodex related blepharitis and eyelid crusting |
| EP3018129A1 (en) * | 2014-11-10 | 2016-05-11 | Novartis Tiergesundheit AG | Diaryl isoxazoline compound |
| UY36570A (es) * | 2015-02-26 | 2016-10-31 | Merial Inc | Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas |
| WO2016164487A1 (en) * | 2015-04-08 | 2016-10-13 | Merial, Inc. | Extended release injectable formulations comprising an isoxazoline active agent, methods and uses thereof |
| HUE055535T2 (hu) | 2015-05-20 | 2021-12-28 | Boehringer Ingelheim Animal Health Usa Inc | Féreghajtó depszipeptid-vegyületek |
| UY37137A (es) | 2016-02-24 | 2017-09-29 | Merial Inc | Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos |
| BR112019002659A2 (pt) * | 2016-08-10 | 2019-05-21 | Bayer Cropscience Aktiengesellschaft | 2-heterociclilimidazolilcarboxamidas substituídas como pesticidas |
| CN110381738B (zh) | 2016-10-14 | 2021-07-16 | 勃林格殷格翰动物保健美国公司 | 农药的和杀寄生物的乙烯基异噁唑啉化合物 |
| JP2020504710A (ja) | 2016-11-16 | 2020-02-13 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | 駆虫性デプシペプチド化合物 |
| WO2018166855A1 (en) | 2017-03-16 | 2018-09-20 | Basf Se | Heterobicyclic substituted dihydroisoxazoles |
| JP2020530850A (ja) | 2017-08-14 | 2020-10-29 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | 殺有害生物および殺寄生生物ピラゾール−イソキサゾリン化合物 |
| MX2020006309A (es) | 2017-12-15 | 2021-01-29 | Tarsus Pharmaceuticals Inc | Fórmulaciones de parasiticida de isoxazolina y métodos para el tratamiento de la blefaritis. |
| TWI812673B (zh) * | 2018-02-12 | 2023-08-21 | 美商富曼西公司 | 用於防治無脊椎害蟲之萘異噁唑啉化合物 |
| IL279977B2 (en) | 2018-07-09 | 2024-06-01 | Boehringer Ingelheim Animal Health Usa Inc | Heterocyclic anthelmintic compounds |
| EP3846793B1 (en) | 2018-09-07 | 2024-01-24 | PIC Therapeutics, Inc. | Eif4e inhibitors and uses thereof |
| EP3883648A1 (en) | 2018-11-20 | 2021-09-29 | Boehringer Ingelheim Animal Health USA Inc. | Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof |
| WO2020191091A1 (en) | 2019-03-19 | 2020-09-24 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic aza-benzothiophene and aza-benzofuran compounds |
| EP3986377A4 (en) * | 2019-06-19 | 2023-07-19 | Tarsus Pharmaceuticals, Inc. | Isoxazoline parasiticide formulations and methods for treating blepharitis |
| US20220249445A1 (en) * | 2019-06-19 | 2022-08-11 | Tarsus Pharmaceuticals, Inc. | Isoxazoline parasiticide formulations and methods for treating blepharitis |
| US20230090439A1 (en) * | 2020-01-29 | 2023-03-23 | Bayer Animal Health Gmbh | Pharmaceutical composition for controlling parasites on non-human organisms |
| AU2021230289A1 (en) | 2020-03-03 | 2022-09-29 | PIC Therapeutics, Inc. | eIF4E inhibitors and uses thereof |
| US11964977B2 (en) | 2020-05-29 | 2024-04-23 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic heterocyclic compounds |
| US20240116854A1 (en) | 2021-01-27 | 2024-04-11 | Intervet Inc. | Cyclopropylamide compounds against parasites in fish |
| EP4284175A1 (en) | 2021-01-27 | 2023-12-06 | Intervet International B.V. | Cyclopropylamide compounds against parasites in fish |
| JP2024532276A (ja) | 2021-08-25 | 2024-09-05 | ピク セラピューティクス， インコーポレイテッド | ｅＩＦ４Ｅ阻害剤及びその使用 |
| CA3229560A1 (en) | 2021-08-25 | 2023-03-02 | Christopher L. Vandeusen | Eif4e inhibitors and uses thereof |
| AU2022377394A1 (en) | 2021-11-01 | 2024-06-13 | Boehringer Ingelheim Vetmedica Gmbh | Anthelmintic pyrrolopyridazine compounds |
| US12258193B2 (en) | 2022-02-17 | 2025-03-25 | Boehringer Ingelheim Vetmedica Gmbh | Method and system for providing a fluid product mailer |
| CN114853748A (zh) * | 2022-05-06 | 2022-08-05 | 武汉工程大学 | 一种含三氟甲烷异噁唑啉类衍生物、其制备方法和应用 |
| NO20240925A1 (en) | 2023-09-15 | 2025-03-17 | Evah Atlantic Inc | Dihydroisoxazole compound for use in reducing ectoparasite infestations on fish |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4026018A1 (de) * | 1990-08-17 | 1992-02-20 | Hoechst Ag | Isoxazoline oder isothiazoline enthaltende pflanzenschuetzende mittel und neue isoxazoline und isothiazoline |
| DE4331448A1 (de) * | 1993-09-16 | 1995-03-23 | Hoechst Schering Agrevo Gmbh | Substituierte Isoxazoline, Verfahren zu deren Herstellung, diese enthaltende Mittel und deren Verwendung als Safener |
| DE19935218A1 (de) * | 1999-07-27 | 2001-02-01 | Aventis Cropscience Gmbh | Isoxazolyl-substituierte Benzoylcyclohexandione, Verfahren zu ihrer Herstellung und ihre Verwendung als Herbizide und Pflanzenwachstumsregulatoren |
| KR100606083B1 (ko) | 2004-11-04 | 2006-07-31 | 삼성전자주식회사 | 광대역 무선 접속 통신 시스템에서 부채널 할당 시스템 및 방법 |
| ES2443690T3 (es) * | 2005-09-02 | 2014-02-20 | Nissan Chemical Industries, Ltd. | Compuesto de benzamida sustituido con isoxazolina y agente controlador de organismos dañinos |
| TW200803740A (en) * | 2005-12-16 | 2008-01-16 | Du Pont | 5-aryl isoxazolines for controlling invertebrate pests |
| TWI600639B (zh) | 2007-08-17 | 2017-10-01 | 杜邦股份有限公司 | 製備５-鹵烷基-４，５-二氫異唑衍生物之化合物 |
| WO2009071500A2 (en) | 2007-12-03 | 2009-06-11 | Novartis Ag | Organic compounds |
| TWI454472B (zh) * | 2008-12-19 | 2014-10-01 | Novartis Ag | 有機化合物 |
-
2012
- 2012-02-09 RU RU2013141413/04A patent/RU2013141413A/ru not_active Application Discontinuation
- 2012-02-09 BR BR112013020520A patent/BR112013020520A2/pt not_active IP Right Cessation
- 2012-02-09 EP EP12704256.2A patent/EP2673273A1/en not_active Withdrawn
- 2012-02-09 US US13/984,701 patent/US20130324538A1/en not_active Abandoned
- 2012-02-09 JP JP2013552962A patent/JP2014505089A/ja not_active Ceased
- 2012-02-09 AR ARP120100434A patent/AR085354A1/es unknown
- 2012-02-09 AU AU2012215440A patent/AU2012215440B2/en not_active Ceased
- 2012-02-09 CA CA2826067A patent/CA2826067A1/en not_active Abandoned
- 2012-02-09 MX MX2013009211A patent/MX2013009211A/es not_active Application Discontinuation
- 2012-02-09 WO PCT/EP2012/052241 patent/WO2012107533A1/en not_active Ceased
- 2012-02-09 CN CN201280008309.4A patent/CN103347880B/zh not_active Expired - Fee Related
- 2012-02-10 TW TW101104306A patent/TWI511966B/zh not_active IP Right Cessation
-
2013
- 2013-07-11 ZA ZA2013/05226A patent/ZA201305226B/en unknown
- 2013-07-12 CO CO13165984A patent/CO6731114A2/es unknown
- 2013-08-07 CL CL2013002296A patent/CL2013002296A1/es unknown
-
2015
- 2015-10-01 US US14/872,669 patent/US20160024062A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AR085354A1 (es) | 2013-09-25 |
| ZA201305226B (en) | 2014-03-26 |
| AU2012215440A1 (en) | 2013-08-01 |
| US20130324538A1 (en) | 2013-12-05 |
| CN103347880B (zh) | 2015-11-25 |
| CA2826067A1 (en) | 2012-08-16 |
| BR112013020520A2 (pt) | 2016-07-12 |
| MX2013009211A (es) | 2013-08-29 |
| EP2673273A1 (en) | 2013-12-18 |
| CO6731114A2 (es) | 2013-08-15 |
| US20160024062A1 (en) | 2016-01-28 |
| JP2014505089A (ja) | 2014-02-27 |
| NZ613191A (en) | 2015-06-26 |
| WO2012107533A1 (en) | 2012-08-16 |
| AU2012215440B2 (en) | 2015-08-27 |
| CL2013002296A1 (es) | 2014-03-14 |
| CN103347880A (zh) | 2013-10-09 |
| TWI511966B (zh) | 2015-12-11 |
| TW201309683A (zh) | 2013-03-01 |
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| HZ9A | Changing address for correspondence with an applicant | ||
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